Result of FASTA (ccds) for
pFN21AB8911
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8911, 250 aa
1>>>pF1KB8911 250 - 250 aa - 250 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.3240+/-0.000824; mu= 8.3995+/- 0.050
mean_var=197.1792+/-41.948, 0's: 0 Z-trim(114.0): 142 B-trim: 863 in 1/53
Lambda= 0.091336
statistics sampled from 14426 (14584) to 14426 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.785), E-opt: 0.2 (0.448), width: 16
Scan time: 2.600
The best scores are: opt bits E(32554)
CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17 ( 250) 1718 237.9 5e-63
CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 ( 260) 714 105.6 3.5e-23
CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 ( 272) 592 89.5 2.5e-18
CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 ( 352) 475 74.2 1.3e-13
CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2 ( 340) 432 68.6 6.4e-12
CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12 ( 342) 427 67.9 1e-11
CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7 ( 410) 416 66.5 3.1e-11
>>CCDS11534.1 HOXB9 gene_id:3219|Hs108|chr17 (250 aa)
initn: 1718 init1: 1718 opt: 1718 Z-score: 1244.9 bits: 237.9 E(32554): 5e-63
Smith-Waterman score: 1718; 100.0% identity (100.0% similar) in 250 aa overlap (1-250:1-250)
10 20 30 40 50 60
pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 LLGAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 HARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKM
190 200 210 220 230 240
250
pF1KB8 KKMNKEQGKE
::::::::::
CCDS11 KKMNKEQGKE
250
>>CCDS8869.1 HOXC9 gene_id:3225|Hs108|chr12 (260 aa)
initn: 769 init1: 485 opt: 714 Z-score: 529.7 bits: 105.6 E(32554): 3.5e-23
Smith-Waterman score: 778; 51.9% identity (68.7% similar) in 262 aa overlap (1-247:1-254)
10 20 30 40 50
pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFP-SGQY-ASSRQPGHAEHL-EFPSCSFQPKAP
:: .: .:.:::::.:::..:: ..:: .: . :..: : . .:::::: ::
CCDS88 MSATGPISNYYVDSLISHDNEDLLASRFPATGAHPAAARPSGLVPDCSDFPSCSFAPKPA
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 VFGASWAPLSPHASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP----GQGQ
::..::::. ..: ::::: :: :..::.:::::: . . : : .
CCDS88 VFSTSWAPVPSQSS----VVYHPY-GPQPHLGADTRYMRTWLEPLSGAVSFPSFPAGGRH
70 80 90 100 110
120 130 140 150 160
pF1KB8 AAVKAEPLLG-----APGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKE
:.: . : .::: .. :.: . : :. . : . ::. ::
CCDS88 YALKPDAYPGRRADCGPGE--GRSYPDY-MYGSPGELRDRAPQTLPSPEADALAGSKHKE
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 RP---DQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLS
. : .:: :::.::::.::::::::::::::::::::::::::::::.::::.:::.
CCDS88 EKADLDPSNPVANWIHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARVLNLT
180 190 200 210 220 230
230 240 250
pF1KB8 ERQVKIWFQNRRMKMKKMNKEQGKE
:::::::::::::::::::::.
CCDS88 ERQVKIWFQNRRMKMKKMNKEKTDKEQS
240 250 260
>>CCDS5409.1 HOXA9 gene_id:3205|Hs108|chr7 (272 aa)
initn: 704 init1: 485 opt: 592 Z-score: 442.6 bits: 89.5 E(32554): 2.5e-18
Smith-Waterman score: 761; 49.5% identity (69.5% similar) in 275 aa overlap (1-250:1-271)
10 20 30 40 50
pF1KB8 MSISGTLSSYYVDSIISHESEDAPPAKFPSGQYASSR--QPGH-----AEHLEFPSCSFQ
:. .:.:..:::::.. . :: .. :.:: . :: . ::: .: ::::
CCDS54 MATTGALGNYYVDSFLL--GADAAD-ELSVGRYAPGTLGQPPRQAATLAEHPDFSPCSFQ
10 20 30 40 50
60 70 80 90 100
pF1KB8 PKAPVFGASWAPLSPHASGSLPS-VYH-----PYIQPQGVPPA----ESRYLRTWLEPAP
:: :::::: :. .....:. ::: ::..::. : : ..::.:.::::.:
CCDS54 SKATVFGASWNPVHAAGANAVPAAVYHHHHHHPYVHPQA-PVAAAAPDGRYMRSWLEPTP
60 70 80 90 100 110
110 120 130 140 150
pF1KB8 RG---EAAPGQGQAAVKAEPLLGAPGELLKQGTPEYSLETSA-GREAVLSNQRPGYG---
. . :.. ..: ::: . :. : :: : : : ...:. :
CCDS54 GALSFAGLPSSRPYGIKPEPLSARRGDCPTLDTHTLSLTDYACGSPPVDREKQPSEGAFS
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 -DNKICEGSEDKERPDQTNPSANWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRR
.: :.. :: : .::.::::::::.:::::::::.::::::::::::::::::::
CCDS54 ENNAENESGGDKPPIDPNNPAANWLHARSTRKKRCPYTKHQTLELEKEFLFNMYLTRDRR
180 190 200 210 220 230
220 230 240 250
pF1KB8 HEVARLLNLSERQVKIWFQNRRMKMKKMNKEQGKE
.::::::::.:::::::::::::::::.::...:.
CCDS54 YEVARLLNLTERQVKIWFQNRRMKMKKINKDRAKDE
240 250 260 270
>>CCDS2267.2 HOXD9 gene_id:3235|Hs108|chr2 (352 aa)
initn: 674 init1: 467 opt: 475 Z-score: 358.0 bits: 74.2 E(32554): 1.3e-13
Smith-Waterman score: 536; 39.9% identity (57.6% similar) in 278 aa overlap (54-247:70-347)
30 40 50 60 70 80
pF1KB8 PPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWA--PLSPHASGSLPSVYHPY
:.. ::.:::. : .: :.... ..::::
CCDS22 PPGPGAQGRPAGVADGPAATAAEFASCSFAPRSAVFSASWSAVPSQPPAAAAMSGLYHPY
40 50 60 70 80 90
90 100 110 120
pF1KB8 IQPQGVPPAES---RYLRTWLEPAPR-----------GEAAPGQGQAAVKAEPLLG----
. : . . : ::.:.:.:: : : ..::.: . . : :
CCDS22 VPPPPLAASASEPGRYVRSWMEPLPGFPGGAGGGGGGGGGGPGRGPSPGPSGPANGRHYG
100 110 120 130 140 150
130 140
pF1KB8 -------APGELL--------------------------KQGT--PEYSLETSAGREAVL
::. .::. ::.: .. ..:.
CCDS22 IKPETRAAPAPATAASTTSSSSTSLSSSSKRTECSVARESQGSSGPEFSCNSFLQEKAAA
160 170 180 190 200 210
150 160 170
pF1KB8 SN--QRPGYG-----------------DNKI--CEGSEDKER---PDQ-----TNPSANW
.. :: : :. : : .:.... :.: .::.:::
CCDS22 ATGGTGPGAGIGAATGTGGSSEPSACSDHPIPGCSLKEEEKQHSQPQQQQLDPNNPAANW
220 230 240 250 260 270
180 190 200 210 220 230
pF1KB8 LHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMK
.::::.::::::::::::::::::::::::::::::.::::.:::.::::::::::::::
CCDS22 IHARSTRKKRCPYTKYQTLELEKEFLFNMYLTRDRRYEVARILNLTERQVKIWFQNRRMK
280 290 300 310 320 330
240 250
pF1KB8 MKKMNKEQGKE
::::.::.
CCDS22 MKKMSKEKCPKGD
340 350
>>CCDS2266.1 HOXD10 gene_id:3236|Hs108|chr2 (340 aa)
initn: 478 init1: 401 opt: 432 Z-score: 327.5 bits: 68.6 E(32554): 6.4e-12
Smith-Waterman score: 436; 39.4% identity (64.2% similar) in 218 aa overlap (35-246:125-327)
10 20 30 40 50 60
pF1KB8 GTLSSYYVDSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQ-PKAPVFGASW
:.. :.. ..: :: . :..:: : .
CCDS22 TQQVPTCSFTTNIKEESNCCMYSDKRNKLISAEVPSY-QRLVPESCPVENPEVPVPG--Y
100 110 120 130 140 150
70 80 90 100 110 120
pF1KB8 APLSP-HASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAPGQGQAAVKAEPLL
:: .:.:. . .:.: . :. ::: : : . : .. : .
CCDS22 FRLSQTYATGKTQEYNN---SPEGSSTV-------MLQLNPRGAAKPQLSAAQLQMEKKM
160 170 180 190 200
130 140 150 160 170
pF1KB8 GAPGELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKIC----EGSEDKERPDQTNPSAN
. : . : . : : .. : ..: .. .. . .:.::. . .:..:
CCDS22 NEP--VSGQEPTKVSQVESPEAKGGLPEERSCLAEVSVSSPEVQEKESKEEIKSDTPTSN
210 220 230 240 250
180 190 200 210 220 230
pF1KB8 WLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRM
:: :.:.:::::::::.:::::::::::::::::.:: :... .::..::::::::::::
CCDS22 WLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKSVNLTDRQVKIWFQNRRM
260 270 280 290 300 310
240 250
pF1KB8 KMKKMNKEQGKE
:.:::..:
CCDS22 KLKKMSRENRIRELTANLTFS
320 330 340
>>CCDS8868.1 HOXC10 gene_id:3226|Hs108|chr12 (342 aa)
initn: 429 init1: 404 opt: 427 Z-score: 323.9 bits: 67.9 E(32554): 1e-11
Smith-Waterman score: 451; 41.7% identity (65.4% similar) in 211 aa overlap (43-246:140-329)
20 30 40 50 60 70
pF1KB8 DSIISHESEDAPPAKFPSGQYASSRQPGHAEHLEFPSCSFQPKAPVFGASWAPLSPHASG
:: : : :. .: ..: .:: ::
CCDS88 VCCMYSAEKRAKSGPEAALYSHPLPESCLGEH-EVPVPSYYRASPSYSA--LDKTPHCSG
110 120 130 140 150 160
80 90 100 110 120
pF1KB8 SLPSVYHPYIQPQGVPPA----ESRYL--RTWLEPAPRGEA-APGQGQAAVKAEPLLGAP
. . :. : .. : :: : .. . .:.... .:. .. .:.: :..:
CCDS88 A-NDFEAPFEQRASLNPRAEHLESPQLGGKVSFPETPKSDSQTPSPNE--IKTEQSLAGP
170 180 190 200 210 220
130 140 150 160 170 180
pF1KB8 GELLKQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSANWLHARSS
.:.: : . ..: ... : .:: : ::. : ..::: :.:.
CCDS88 -----KGSPSESEK----ERAKAADSSPDTSDN------EAKEEIKAENTTGNWLTAKSG
230 240 250 260
190 200 210 220 230 240
pF1KB8 RKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRRMKMKKMNK
:::::::::.:::::::::::::::::.:: :... .::..:::::::::::::.::::.
CCDS88 RKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISKTINLTDRQVKIWFQNRRMKLKKMNR
270 280 290 300 310 320
250
pF1KB8 EQGKE
:
CCDS88 ENRIRELTSNFNFT
330 340
>>CCDS5410.2 HOXA10 gene_id:3206|Hs108|chr7 (410 aa)
initn: 447 init1: 390 opt: 416 Z-score: 315.2 bits: 66.5 E(32554): 3.1e-11
Smith-Waterman score: 416; 47.8% identity (68.6% similar) in 159 aa overlap (100-246:244-397)
70 80 90 100 110 120
pF1KB8 ASGSLPSVYHPYIQPQGVPPAESRYLRTWLEPAPRGEAAP-----GQGQAAVKAEPLLGA
.: :: : :...:: : . : .
CCDS54 FRLSQAYGTAKGYGSGGGGAQQLGAGPFPAQPPGRGFDLPPALASGSADAARKERALDSP
220 230 240 250 260 270
130 140 150 160 170
pF1KB8 PGELL-------KQGTPEYSLETSAGREAVLSNQRPGYGDNKICEGSEDKERPDQTNPSA
: : .:: : .::..: :: :. .... .:. .. . .:
CCDS54 PPPTLACGSGGGSQGDEEAHASSSAAEE--LS---PAPSESSKASPEKDSLGNSKGENAA
280 290 300 310 320
180 190 200 210 220 230
pF1KB8 NWLHARSSRKKRCPYTKYQTLELEKEFLFNMYLTRDRRHEVARLLNLSERQVKIWFQNRR
::: :.:.:::::::::.:::::::::::::::::.:: :..: ..:..:::::::::::
CCDS54 NWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRR
330 340 350 360 370 380
240 250
pF1KB8 MKMKKMNKEQGKE
::.::::.:
CCDS54 MKLKKMNRENRIRELTANFNFS
390 400 410
250 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:27:54 2016 done: Fri Nov 4 16:27:55 2016
Total Scan time: 2.600 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]