Result of FASTA (omim) for
pFN21AB8885
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8885, 193 aa
1>>>pF1KB8885 193 - 193 aa - 193 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.4185+/-0.000298; mu= -4.0374+/- 0.019
mean_var=205.3358+/-43.351, 0's: 0 Z-trim(123.6): 9 B-trim: 1992 in 1/56
Lambda= 0.089504
statistics sampled from 43697 (43712) to 43697 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.811), E-opt: 0.2 (0.513), width: 16
Scan time: 6.300
The best scores are: opt bits E(85289)
NP_001138358 (OMIM: 300149) cbp/p300-interacting t ( 193) 1281 176.5 2.3e-44
NP_001138359 (OMIM: 300149) cbp/p300-interacting t ( 193) 1281 176.5 2.3e-44
NP_004134 (OMIM: 300149) cbp/p300-interacting tran ( 193) 1281 176.5 2.3e-44
XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-in ( 219) 1281 176.5 2.6e-44
NP_001138357 (OMIM: 300149) cbp/p300-interacting t ( 219) 1281 176.5 2.6e-44
NP_001161860 (OMIM: 602937,614431,614433) cbp/p300 ( 270) 258 44.5 0.00018
NP_006070 (OMIM: 602937,614431,614433) cbp/p300-in ( 270) 258 44.5 0.00018
NP_001161861 (OMIM: 602937,614431,614433) cbp/p300 ( 275) 258 44.5 0.00018
NP_597724 (OMIM: 606815) cbp/p300-interacting tran ( 184) 254 43.9 0.00019
>>NP_001138358 (OMIM: 300149) cbp/p300-interacting trans (193 aa)
initn: 1281 init1: 1281 opt: 1281 Z-score: 917.4 bits: 176.5 E(85289): 2.3e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_001 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
130 140 150 160 170 180
190
pF1KB8 NEFDFTADFPSSC
:::::::::::::
NP_001 NEFDFTADFPSSC
190
>>NP_001138359 (OMIM: 300149) cbp/p300-interacting trans (193 aa)
initn: 1281 init1: 1281 opt: 1281 Z-score: 917.4 bits: 176.5 E(85289): 2.3e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_001 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
130 140 150 160 170 180
190
pF1KB8 NEFDFTADFPSSC
:::::::::::::
NP_001 NEFDFTADFPSSC
190
>>NP_004134 (OMIM: 300149) cbp/p300-interacting transact (193 aa)
initn: 1281 init1: 1281 opt: 1281 Z-score: 917.4 bits: 176.5 E(85289): 2.3e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:1-193)
10 20 30 40 50 60
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMQLQKLNSQYQGMAAATPGQPGEAGP
:::::::::::::::::::::::::::::::::::.::::::::::::::::::::::::
NP_004 PTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLASMHLQKLNSQYQGMAAATPGQPGEAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRANELPELWLGQ
130 140 150 160 170 180
190
pF1KB8 NEFDFTADFPSSC
:::::::::::::
NP_004 NEFDFTADFPSSC
190
>>XP_011529260 (OMIM: 300149) PREDICTED: cbp/p300-intera (219 aa)
initn: 1281 init1: 1281 opt: 1281 Z-score: 916.6 bits: 176.5 E(85289): 2.6e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:27-219)
10 20 30
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
::::::::::::::::::::::::::::::::::
XP_011 MEPSAQQLQLAASLPANLSNFCQGSEMPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 MQLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
130 140 150 160 170 180
160 170 180 190
pF1KB8 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
:::::::::::::::::::::::::::::::::::::::
XP_011 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
190 200 210
>>NP_001138357 (OMIM: 300149) cbp/p300-interacting trans (219 aa)
initn: 1281 init1: 1281 opt: 1281 Z-score: 916.6 bits: 176.5 E(85289): 2.6e-44
Smith-Waterman score: 1281; 99.5% identity (100.0% similar) in 193 aa overlap (1-193:27-219)
10 20 30
pF1KB8 MPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
::::::::::::::::::::::::::::::::::
NP_001 MEPSAQQLQLAASLPANLSNFCQGSEMPTTSRPALDVKGGTSPAKEDANQEMSSVAYSNL
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPPTKPPSFNLHPAPHLLAS
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 MQLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MHLQKLNSQYQGMAAATPGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVD
130 140 150 160 170 180
160 170 180 190
pF1KB8 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
:::::::::::::::::::::::::::::::::::::::
NP_001 EEVLMSLVVELGLDRANELPELWLGQNEFDFTADFPSSC
190 200 210
>>NP_001161860 (OMIM: 602937,614431,614433) cbp/p300-int (270 aa)
initn: 344 init1: 248 opt: 258 Z-score: 201.3 bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:89-259)
20 30 40 50 60 70
pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
:.. :... : :..:.:. . .
NP_001 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
60 70 80 90 100 110
80 90 100 110
pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE
. :: :: :: :. :.. :.... ...::: ::
NP_001 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG
120 130 140 150 160 170
120 130 140 150 160
pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.:::
NP_001 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD
180 190 200 210 220 230
170 180 190
pF1KB8 RANELPELWLGQNEFDFTADFPSSC
: .:::::::::::::: .::
NP_001 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
240 250 260 270
>>NP_006070 (OMIM: 602937,614431,614433) cbp/p300-intera (270 aa)
initn: 344 init1: 248 opt: 258 Z-score: 201.3 bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:89-259)
20 30 40 50 60 70
pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
:.. :... : :..:.:. . .
NP_006 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
60 70 80 90 100 110
80 90 100 110
pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE
. :: :: :: :. :.. :.... ...::: ::
NP_006 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG
120 130 140 150 160 170
120 130 140 150 160
pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.:::
NP_006 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD
180 190 200 210 220 230
170 180 190
pF1KB8 RANELPELWLGQNEFDFTADFPSSC
: .:::::::::::::: .::
NP_006 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
240 250 260 270
>>NP_001161861 (OMIM: 602937,614431,614433) cbp/p300-int (275 aa)
initn: 344 init1: 248 opt: 258 Z-score: 201.2 bits: 44.5 E(85289): 0.00018
Smith-Waterman score: 308; 36.3% identity (59.1% similar) in 171 aa overlap (48-189:94-264)
20 30 40 50 60 70
pF1KB8 AKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSSGSPIGSPTTTPP
:.. :... : :..:.:. . .
NP_001 GAGNMNATSGIRHAMGPGTVNGGHPPSALAPAARFNNSQFMGPPVASQGGSLPASMQLQK
70 80 90 100 110 120
80 90 100 110
pF1KB8 TKPPSFNLHPAPHL--------LASMQLQKLNSQYQGM------AAATPG------QPGE
. :: :: :: :. :.. :.... ...::: ::
NP_001 LNNQYFNHHPYPHNHYMPDLHPAAGHQMNGTNQHFRDCNPKHSGGSSTPGGSGGSSTPGG
130 140 150 160 170 180
120 130 140 150 160
pF1KB8 AGPLQNWDFGAQAGGAESLS---PSAGAQSPA------IIDSDPVDEEVLMSLVVELGLD
.: .. :.. .:. : : :.. :. :: .::.: .:::::::::.:.:::
NP_001 SGSSSGGGAGSSNSGGGSGSGNMPASVAHVPAAMLPPNVIDTDFIDEEVLMSLVIEMGLD
190 200 210 220 230 240
170 180 190
pF1KB8 RANELPELWLGQNEFDFTADFPSSC
: .:::::::::::::: .::
NP_001 RIKELPELWLGQNEFDFMTDFVCKQQPSRVSC
250 260 270
>>NP_597724 (OMIM: 606815) cbp/p300-interacting transact (184 aa)
initn: 230 init1: 147 opt: 254 Z-score: 201.0 bits: 43.9 E(85289): 0.00019
Smith-Waterman score: 254; 34.5% identity (55.0% similar) in 171 aa overlap (36-192:14-176)
10 20 30 40 50 60
pF1KB8 RPALDVKGGTSPAKEDANQEMSSVAYSNLAVKDRKAVAILHYPGVASNGTKASGAPTSSS
:. ..: : : . . .: .:.
NP_597 MADHLMLAEGYRLVQRPPSAAAAHGPHALRTLPPYAGPGLDSG
10 20 30 40
70 80 90 100 110
pF1KB8 GSPIGSPTTTPPTK-----------PPS-FNLHPA--PHLLASMQLQKLNSQYQGMAAAT
: :.: :: . ::: :. :: : . .:: . . : : :::
NP_597 LRPRGAPLGPPPPRQPGALAYGAFGPPSSFQPFPAVPPPAAGIAHLQPVATPYPGRAAAP
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB8 PGQPGEAGPLQNWDFGAQAGGAESLSPSAGAQSPAIIDSDPVDEEVLMSLVVELGLDRAN
:. :: :: : : . . . .: :.. . .:.. .:::.: :: .:::: :.
NP_597 PNAPG--GPP-----GPQPAPSAA-APPPPAHALGGMDAELIDEEALTSLELELGLHRVR
110 120 130 140 150
180 190
pF1KB8 ELPELWLGQNEFDFTADFPSSC
:::::.:::.::: .:. :.
NP_597 ELPELFLGQSEFDCFSDLGSAPPAGSVSC
160 170 180
193 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:19:47 2016 done: Fri Nov 4 16:19:48 2016
Total Scan time: 6.300 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]