Result of FASTA (omim) for
pFN21AB8760
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8760, 203 aa
1>>>pF1KB8760 203 - 203 aa - 203 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6842+/-0.00029; mu= 13.5845+/- 0.018
mean_var=117.4036+/-24.794, 0's: 0 Z-trim(121.1): 78 B-trim: 1194 in 1/57
Lambda= 0.118368
statistics sampled from 37086 (37178) to 37086 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.793), E-opt: 0.2 (0.436), width: 16
Scan time: 5.330
The best scores are: opt bits E(85289)
XP_005266707 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 1416 251.7 6e-67
XP_005266709 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 1416 251.7 6e-67
XP_011524180 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 1416 251.7 6e-67
XP_016881102 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 1416 251.7 6e-67
NP_775828 (OMIM: 616512) E3 ubiquitin-protein liga ( 203) 1416 251.7 6e-67
XP_016881101 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 1416 251.7 6e-67
XP_011524181 (OMIM: 616512) PREDICTED: E3 ubiquiti ( 203) 1416 251.7 6e-67
NP_061935 (OMIM: 617163) RING finger protein 186 [ ( 227) 202 44.4 0.00017
XP_016869975 (OMIM: 254110,602290,615988) PREDICTE ( 653) 207 45.8 0.00019
XP_005251870 (OMIM: 254110,602290,615988) PREDICTE ( 653) 207 45.8 0.00019
NP_001093149 (OMIM: 254110,602290,615988) E3 ubiqu ( 653) 207 45.8 0.00019
XP_011516700 (OMIM: 254110,602290,615988) PREDICTE ( 653) 207 45.8 0.00019
NP_036342 (OMIM: 254110,602290,615988) E3 ubiquiti ( 653) 207 45.8 0.00019
>>XP_005266707 (OMIM: 616512) PREDICTED: E3 ubiquitin-pr (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
XP_005 FLLGIVLHNMSCISKRFTVISCG
190 200
>>XP_005266709 (OMIM: 616512) PREDICTED: E3 ubiquitin-pr (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
XP_005 FLLGIVLHNMSCISKRFTVISCG
190 200
>>XP_011524180 (OMIM: 616512) PREDICTED: E3 ubiquitin-pr (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
XP_011 FLLGIVLHNMSCISKRFTVISCG
190 200
>>XP_016881102 (OMIM: 616512) PREDICTED: E3 ubiquitin-pr (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
XP_016 FLLGIVLHNMSCISKRFTVISCG
190 200
>>NP_775828 (OMIM: 616512) E3 ubiquitin-protein ligase R (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
NP_775 FLLGIVLHNMSCISKRFTVISCG
190 200
>>XP_016881101 (OMIM: 616512) PREDICTED: E3 ubiquitin-pr (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
XP_016 FLLGIVLHNMSCISKRFTVISCG
190 200
>>XP_011524181 (OMIM: 616512) PREDICTED: E3 ubiquitin-pr (203 aa)
initn: 1416 init1: 1416 opt: 1416 Z-score: 1322.9 bits: 251.7 E(85289): 6e-67
Smith-Waterman score: 1416; 100.0% identity (100.0% similar) in 203 aa overlap (1-203:1-203)
10 20 30 40 50 60
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTCCSVCLQQMRTSQKDVRCPWCRGVTKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFIKLPSNGCYMLPLPISKERALLPGDMGCR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSSTWSGVCTVILVACVLV
130 140 150 160 170 180
190 200
pF1KB8 FLLGIVLHNMSCISKRFTVISCG
:::::::::::::::::::::::
XP_011 FLLGIVLHNMSCISKRFTVISCG
190 200
>>NP_061935 (OMIM: 617163) RING finger protein 186 [Homo (227 aa)
initn: 182 init1: 129 opt: 202 Z-score: 201.9 bits: 44.4 E(85289): 0.00017
Smith-Waterman score: 202; 38.6% identity (60.2% similar) in 83 aa overlap (5-84:33-114)
10 20 30
pF1KB8 METLSQDSLLECQICFNYYSPRRRPKLLDCKHTC
: . ::: .: . :: : :::: :.:.
NP_061 CTKTLQQSQPISAGATTTTTAVAPAGGHSGSTECDLECLVCREPYSCPRLPKLLACQHAF
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB8 CSVCLQQMRTSQKD---VRCPWCRGVTKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVF
:..::. . : . . :: :: :: .: :. . .: : :.. .: : :
NP_061 CAICLKLLLCVQDNTWSITCPLCRKVTAVPGGL-ICSLRDHEAVVGQLAQPCTEVSLCPQ
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB8 IKLPSNGCYMLPLPISKERALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQGGAPQEAV
NP_061 GLVDPADLAAGHPSLVGEDGQDEVSANHVAARRLAAHLLLLALLIILIGPFIYPGVLRWV
130 140 150 160 170 180
>>XP_016869975 (OMIM: 254110,602290,615988) PREDICTED: E (653 aa)
initn: 201 init1: 92 opt: 207 Z-score: 201.0 bits: 45.8 E(85289): 0.00019
Smith-Waterman score: 207; 35.5% identity (61.7% similar) in 107 aa overlap (4-99:9-112)
10 20 30 40 50
pF1KB8 METLSQDSL---LECQICFNYYSPRR-RPKLLDCKHTCCSVCLQQMRTSQKD-VR
:. :.: ::: ::.. .. .. ::::: : :: : ::... .:. . ::
XP_016 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
60 70 80 90 100
pF1KB8 CPWCRGVTKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFI------KLPSNGCYMLPL
::.: .:.. :..:: :. :: .: :: . ... .:: . :
XP_016 CPFCSKITRIT---SLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGL
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 PISKERALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSS
XP_016 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL
120 130 140 150 160 170
>>XP_005251870 (OMIM: 254110,602290,615988) PREDICTED: E (653 aa)
initn: 201 init1: 92 opt: 207 Z-score: 201.0 bits: 45.8 E(85289): 0.00019
Smith-Waterman score: 207; 35.5% identity (61.7% similar) in 107 aa overlap (4-99:9-112)
10 20 30 40 50
pF1KB8 METLSQDSL---LECQICFNYYSPRR-RPKLLDCKHTCCSVCLQQMRTSQKD-VR
:. :.: ::: ::.. .. .. ::::: : :: : ::... .:. . ::
XP_005 MAAAAASHLNLDALREVLECPICMESFTEEQLRPKLLHCGHTICRQCLEKLLASSINGVR
10 20 30 40 50 60
60 70 80 90 100
pF1KB8 CPWCRGVTKLPPGFSVSQLPDDPEVLAVIAIPHTSEHTPVFI------KLPSNGCYMLPL
::.: .:.. :..:: :. :: .: :: . ... .:: . :
XP_005 CPFCSKITRIT---SLTQLTDNLTVLKIIDTAGLSEAVGLLMCRSCGRRLPRQFCRSCGL
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 PISKERALLPGDMGCRLLPGSQQKSVTVVTIPAEQQPLQGGAPQEAVEEEQDRRGVVKSS
XP_005 VLCEPCREADHQPPGHCTLPVKEAAEERRRDFGEKLTRLRELMGELQRRKAALEGVSKDL
120 130 140 150 160 170
203 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 15:21:18 2016 done: Fri Nov 4 15:21:19 2016
Total Scan time: 5.330 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]