Result of FASTA (omim) for
pFN21AB8726
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8726, 358 aa
1>>>pF1KB8726 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.5442+/-0.000666; mu= -3.7667+/- 0.039
mean_var=667.3320+/-158.026, 0's: 0 Z-trim(113.9): 1712 B-trim: 378 in 1/57
Lambda= 0.049648
statistics sampled from 21185 (23493) to 21185 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.643), E-opt: 0.2 (0.275), width: 16
Scan time: 8.100
The best scores are: opt bits E(85289)
NP_443732 (OMIM: 610710) testis-specific serine/th ( 358) 2393 187.3 4.5e-47
NP_114417 (OMIM: 610709) testis-specific serine/th ( 367) 1597 130.3 6.6e-30
NP_443073 (OMIM: 607660) testis-specific serine/th ( 268) 893 79.7 8.6e-15
NP_114426 (OMIM: 610712) testis-specific serine/th ( 273) 818 74.3 3.6e-13
XP_011527776 (OMIM: 605705,616341) PREDICTED: seri ( 734) 670 64.4 8.9e-10
NP_775490 (OMIM: 605705,616341) serine/threonine-p ( 783) 670 64.5 9.2e-10
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765) 632 61.8 6e-09
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765) 632 61.8 6e-09
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765) 632 61.8 6e-09
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 630 61.5 6.1e-09
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 630 61.6 6.4e-09
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 630 61.6 6.4e-09
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 630 61.6 6.4e-09
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 630 61.6 6.5e-09
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 630 61.6 6.5e-09
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660) 629 61.4 6.5e-09
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 630 61.6 6.5e-09
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 630 61.6 6.5e-09
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 630 61.6 6.5e-09
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 630 61.6 6.5e-09
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 630 61.6 6.6e-09
NP_056006 (OMIM: 608973) serine/threonine-protein ( 926) 629 61.7 7.6e-09
NP_001156769 (OMIM: 600526) serine/threonine-prote ( 709) 624 61.1 8.6e-09
XP_016872913 (OMIM: 614776) PREDICTED: serine/thre (1213) 629 61.9 8.7e-09
NP_001156768 (OMIM: 600526) serine/threonine-prote ( 719) 624 61.1 8.7e-09
NP_004945 (OMIM: 600526) serine/threonine-protein ( 724) 624 61.1 8.7e-09
XP_011543100 (OMIM: 600526) PREDICTED: serine/thre ( 729) 624 61.1 8.7e-09
XP_016872800 (OMIM: 600526) PREDICTED: serine/thre ( 738) 624 61.2 8.8e-09
XP_011543099 (OMIM: 600526) PREDICTED: serine/thre ( 739) 624 61.2 8.8e-09
XP_011543098 (OMIM: 600526) PREDICTED: serine/thre ( 744) 624 61.2 8.8e-09
NP_059672 (OMIM: 600526) serine/threonine-protein ( 745) 624 61.2 8.8e-09
XP_011543097 (OMIM: 600526) PREDICTED: serine/thre ( 745) 624 61.2 8.8e-09
NP_001268678 (OMIM: 614776) serine/threonine-prote (1261) 629 61.9 8.8e-09
XP_005271541 (OMIM: 614776) PREDICTED: serine/thre (1261) 629 61.9 8.8e-09
XP_011543096 (OMIM: 600526) PREDICTED: serine/thre ( 753) 624 61.2 8.9e-09
XP_016872799 (OMIM: 600526) PREDICTED: serine/thre ( 763) 624 61.2 8.9e-09
XP_011541024 (OMIM: 614776) PREDICTED: serine/thre (1309) 629 61.9 9e-09
NP_001273055 (OMIM: 606511) serine/threonine-prote ( 780) 624 61.2 9e-09
XP_005273191 (OMIM: 606511) PREDICTED: serine/thre ( 781) 624 61.2 9e-09
NP_079440 (OMIM: 614776) serine/threonine-protein (1321) 629 62.0 9e-09
XP_005271539 (OMIM: 614776) PREDICTED: serine/thre (1321) 629 62.0 9e-09
XP_011543095 (OMIM: 600526) PREDICTED: serine/thre ( 784) 624 61.2 9e-09
XP_011507863 (OMIM: 606511) PREDICTED: serine/thre ( 788) 624 61.2 9.1e-09
NP_001034558 (OMIM: 600526) serine/threonine-prote ( 788) 624 61.2 9.1e-09
XP_011543094 (OMIM: 600526) PREDICTED: serine/thre ( 793) 624 61.2 9.1e-09
NP_061120 (OMIM: 606511) serine/threonine-protein ( 795) 624 61.2 9.1e-09
NP_001273053 (OMIM: 606511) serine/threonine-prote ( 796) 624 61.2 9.1e-09
XP_011543093 (OMIM: 600526) PREDICTED: serine/thre ( 798) 624 61.2 9.1e-09
XP_011543092 (OMIM: 600526) PREDICTED: serine/thre ( 799) 624 61.2 9.1e-09
XP_011543091 (OMIM: 600526) PREDICTED: serine/thre ( 808) 624 61.2 9.2e-09
>>NP_443732 (OMIM: 610710) testis-specific serine/threon (358 aa)
initn: 2393 init1: 2393 opt: 2393 Z-score: 966.1 bits: 187.3 E(85289): 4.5e-47
Smith-Waterman score: 2393; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
250 260 270 280 290 300
310 320 330 340 350
pF1KB8 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_443 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
310 320 330 340 350
>>NP_114417 (OMIM: 610709) testis-specific serine/threon (367 aa)
initn: 1602 init1: 1566 opt: 1597 Z-score: 657.9 bits: 130.3 E(85289): 6.6e-30
Smith-Waterman score: 1597; 71.8% identity (89.4% similar) in 330 aa overlap (1-330:1-327)
10 20 30 40 50 60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
::::.::...::..:::::.:::::::::::::::::::.:::::::.:.::.:.:::::
NP_114 MDDAAVLKRRGYLLGINLGEGSYAKVKSAYSERLKFNVAIKIIDRKKAPADFLEKFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
..::: .:: :::::::::::: :..::.:::.:::::::.:: .:::::: ::: :.::
NP_114 IEILAMLNHCSIIKTYEIFETSHGKVYIVMELAVQGDLLELIKTRGALHEDEARKKFHQL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
: :.:::::::.:::::::.:::::::::::::::.::::::::..::. :::::::: :
NP_114 SLAIKYCHDLDVVHRDLKCDNLLLDKDFNIKLSDFSFSKRCLRDDSGRMALSKTFCGSPA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
::::::::.::::::::::::::::::::::::::::::.:.:::::::::::.:::::.
NP_114 YAAPEVLQGIPYQPKVYDIWSLGVILYIMVCGSMPYDDSNIKKMLRIQKEHRVNFPRSKH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
:: :::::::.::::::..:::::::::: :.:: : ... :.....:::.. .:
NP_114 LTGECKDLIYHMLQPDVNRRLHIDEILSHCWMQP-KARGSPSVAINKEGESSRGTEPLWT
250 260 270 280 290
310 320 330 340 350
pF1KB8 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
. : :.. :: . . . . ::..
NP_114 PEPG--SDKKSATKLEPEGEAQPQAQPETKPEGTAMQMSRQSEILGFPSKPSTMETEEGP
300 310 320 330 340 350
>>NP_443073 (OMIM: 607660) testis-specific serine/threon (268 aa)
initn: 843 init1: 458 opt: 893 Z-score: 386.5 bits: 79.7 E(85289): 8.6e-15
Smith-Waterman score: 893; 47.4% identity (77.9% similar) in 272 aa overlap (1-272:1-265)
10 20 30 40 50 60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
:.: : ..:: .: ..:.:.:.::: :.:.. . .::.:.::. : .:..::::::
NP_443 MED--FLLSNGYQLGKTIGEGTYSKVKEAFSKKHQRKVAIKVIDKMGGPEEFIQRFLPRE
10 20 30 40 50
70 80 90 100 110 120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
..:. :..: .::..::..:..::.: ..:::. ::... . : : :. :. .:::.
NP_443 LQIVRTLDHKNIIQVYEMLESADGKICLVMELAEGGDVFDCVLNGGPLPESRAKALFRQM
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSNGRIILSKTFCGSAA
:..::: ..:::::::: :: . ::.::.::::.: : :. . ::.:::::.:
NP_443 VEAIRYCHGCGVAHRDLKCENALL-QGFNLKLTDFGFAK-VLPKSHRE--LSQTFCGSTA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB8 YAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSKN
::::::::.::.. : :.::.::.::.:.:.:.:.::.:: ::: :... :.:: .
NP_443 YAAPEVLQGIPHDSKKGDVWSMGVVLYVMLCASLPFDDTDIPKMLW-QQQKGVSFPTHLS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB8 LTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKLD
.. .:.::. :.:.::. : :.:. : ::
NP_443 ISADCQDLLKRLLEPDMILRPSIEEVSWHPWLAST
240 250 260
310 320 330 340 350
pF1KB8 TKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
>>NP_114426 (OMIM: 610712) testis-specific serine/threon (273 aa)
initn: 765 init1: 292 opt: 818 Z-score: 357.4 bits: 74.3 E(85289): 3.6e-13
Smith-Waterman score: 818; 46.4% identity (74.5% similar) in 274 aa overlap (1-273:1-268)
10 20 30 40 50 60
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDFVERFLPRE
:. .: . :: .: ..:.:::.::: : :.. : .::.:..::...: :::..:::::
NP_114 MSGDKLLSELGYKLGRTIGEGSYSKVKVATSKKYKGTVAIKVVDRRRAPPDFVNKFLPRE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 MDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQGALHEDVARKMFRQL
..:: : : :....:..:. .:..::.:: .. :::. .. .: . :: .: :.
NP_114 LSILRGVRHPHIVHVFEFIEVCNGKLYIVME-AAATDLLQAVQRNGRIPGVQARDLFAQI
70 80 90 100 110
130 140 150 160 170
pF1KB8 SSAVKYCHDLDIVHRDLKCENLLLDKDFN-IKLSDFGFSKRCLRDSNGRIILSKTFCGSA
..::.: :: .:::::::::.::. : .::.::::. :...: :: :.::::
NP_114 AGAVRYLHDHHLVHRDLKCENVLLSPDERRVKLTDFGFG----RQAHGYPDLSTTYCGSA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 AYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKEHRVDFPRSK
:::.:::: .:::.:: ::.::.::.::.:: : ::.::::: . : ::. : .:..
NP_114 AYASPEVLLGIPYDPKKYDVWSMGVVLYVMVTGCMPFDDSDIAGLPRRQKRG-VLYPEGL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 NLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSASFKREGEGKYRAECKL
.:. .:: :: ..:: . : : .. . ::.
NP_114 ELSERCKALIAELLQFSPSARPSAGQVARNCWLRAGDSG
240 250 260 270
300 310 320 330 340 350
pF1KB8 DTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHISGAEVGKAST
>>XP_011527776 (OMIM: 605705,616341) PREDICTED: serine/t (734 aa)
initn: 621 init1: 267 opt: 670 Z-score: 296.5 bits: 64.4 E(85289): 8.9e-10
Smith-Waterman score: 670; 41.1% identity (68.4% similar) in 285 aa overlap (7-285:22-297)
10 20 30 40
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDR
:: : . .::::..: :: : . : .::.::::.
XP_011 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 KKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQ
. .. .:.. ::.... .:: ::: :...::.: .::. :.. .:...... .
XP_011 TRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSN
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 GALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDS
: : :. ::: : :. :::.:::: ::::::: :::::: ...:::.::::.. .
XP_011 GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 NGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML
.:. . .:.::: ::::::... :. :::::::.::..::::.:.: .. .
XP_011 SGEPL--STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLR
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 RIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL--QP--PKPK--A
. : : .: .. .:..:: ::: : ..:. : .: .: :. .: : : :
XP_011 QRVLEGRFRIPFF--MSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 TSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAE
:. :.
XP_011 FSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVEVPQEGLSTDPFRPALLCPQPQTLVQSV
300 310 320 330 340 350
>>NP_775490 (OMIM: 605705,616341) serine/threonine-prote (783 aa)
initn: 621 init1: 267 opt: 670 Z-score: 296.3 bits: 64.5 E(85289): 9.2e-10
Smith-Waterman score: 670; 41.1% identity (68.4% similar) in 285 aa overlap (7-285:22-297)
10 20 30 40
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDR
:: : . .::::..: :: : . : .::.::::.
NP_775 MVIMSEFSADPAGQGQGQQKPLRVGFYDIERTLGKGNFAVVKLARHRVTKTQVAIKIIDK
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 KKTPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQ
. .. .:.. ::.... .:: ::: :...::.: .::. :.. .:...... .
NP_775 TRLDSSNLEKIY-REVQLMKLLNHPHIIKLYQVMETKD-MLYIVTEFAKNGEMFDYLTSN
70 80 90 100 110
110 120 130 140 150 160
pF1KB8 GALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDS
: : :. ::: : :. :::.:::: ::::::: :::::: ...:::.::::.. .
NP_775 GHLSENEARKKFWQILSAVEYCHDHHIVHRDLKTENLLLDGNMDIKLADFGFGN---FYK
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 NGRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML
.:. . .:.::: ::::::... :. :::::::.::..::::.:.: .. .
NP_775 SGEPL--STWCGSPPYAAPEVFEGKEYEGPQLDIWSLGVVLYVLVCGSLPFDGPNLPTLR
180 190 200 210 220 230
230 240 250 260 270
pF1KB8 RIQKEHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWL--QP--PKPK--A
. : : .: .. .:..:: ::: : ..:. : .: .: :. .: : : :
NP_775 QRVLEGRFRIPFF--MSQDCESLIRRMLVVDPARRITIAQIRQHRWMRAEPCLPGPACPA
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 TSSASFKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAE
:. :.
NP_775 FSAHSYTSNLGDYDEQALGIMQTLGVDRQRTVESLQNSSYNHFAAIYYLLLERLKEYRNA
300 310 320 330 340 350
>>NP_001094064 (OMIM: 612760) SNF-related serine/threoni (765 aa)
initn: 557 init1: 178 opt: 632 Z-score: 281.6 bits: 61.8 E(85289): 6e-09
Smith-Waterman score: 632; 39.9% identity (68.3% similar) in 281 aa overlap (9-277:5-276)
10 20 30 40 50
pF1KB8 MDDATVLRKKGY---IVGI-----NLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDF
:.:: :.:. .::.: .: :: : .::::.::. : : .
NP_001 MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT-L
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 VERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI-KCQGALHED
. : .:. . :.: .:.. ::...:. ..:.:.::: ::....: : . .:.::
NP_001 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQT-KLYLILELGDGGDMFDYIMKHEEGLNED
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL-DKDFNIKLSDFGFSKRCLRDSNGRII
.:.:.: :. :..::: : .:::::: ::... .:. .::.:::::.. . :. .
NP_001 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKF---QPGKKL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE
: ::: ::.:::.: . :. . :::::::::...:::. :..... . : . .
NP_001 --TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD
180 190 200 210 220
240 250 260 270 280
pF1KB8 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ--PPKPKATSSASFKRE
. : .... :::::: :::: : ..: ..:: .: ::: :.:
NP_001 CKYTVP--SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSY
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 GEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHI
NP_001 KNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQT
290 300 310 320 330 340
>>NP_060189 (OMIM: 612760) SNF-related serine/threonine- (765 aa)
initn: 557 init1: 178 opt: 632 Z-score: 281.6 bits: 61.8 E(85289): 6e-09
Smith-Waterman score: 632; 39.9% identity (68.3% similar) in 281 aa overlap (9-277:5-276)
10 20 30 40 50
pF1KB8 MDDATVLRKKGY---IVGI-----NLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDF
:.:: :.:. .::.: .: :: : .::::.::. : : .
NP_060 MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT-L
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 VERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI-KCQGALHED
. : .:. . :.: .:.. ::...:. ..:.:.::: ::....: : . .:.::
NP_060 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQT-KLYLILELGDGGDMFDYIMKHEEGLNED
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL-DKDFNIKLSDFGFSKRCLRDSNGRII
.:.:.: :. :..::: : .:::::: ::... .:. .::.:::::.. . :. .
NP_060 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKF---QPGKKL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE
: ::: ::.:::.: . :. . :::::::::...:::. :..... . : . .
NP_060 --TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD
180 190 200 210 220
240 250 260 270 280
pF1KB8 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ--PPKPKATSSASFKRE
. : .... :::::: :::: : ..: ..:: .: ::: :.:
NP_060 CKYTVP--SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSY
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 GEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHI
NP_060 KNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQT
290 300 310 320 330 340
>>XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ser (765 aa)
initn: 557 init1: 178 opt: 632 Z-score: 281.6 bits: 61.8 E(85289): 6e-09
Smith-Waterman score: 632; 39.9% identity (68.3% similar) in 281 aa overlap (9-277:5-276)
10 20 30 40 50
pF1KB8 MDDATVLRKKGY---IVGI-----NLGKGSYAKVKSAYSERLKFNVAVKIIDRKKTPTDF
:.:: :.:. .::.: .: :: : .::::.::. : : .
XP_005 MAGFKRGYDGKIAGLYDLDKTLGRGHFAVVKLARHVFTGEKVAVKVIDKTKLDT-L
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 VERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFI-KCQGALHED
. : .:. . :.: .:.. ::...:. ..:.:.::: ::....: : . .:.::
XP_005 ATGHLFQEVRCMKLVQHPNIVRLYEVIDTQT-KLYLILELGDGGDMFDYIMKHEEGLNED
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB8 VARKMFRQLSSAVKYCHDLDIVHRDLKCENLLL-DKDFNIKLSDFGFSKRCLRDSNGRII
.:.:.: :. :..::: : .:::::: ::... .:. .::.:::::.. . :. .
XP_005 LAKKYFAQIVHAISYCHKLHVVHRDLKPENVVFFEKQGLVKLTDFGFSNKF---QPGKKL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB8 LSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKMLRIQKE
: ::: ::.:::.: . :. . :::::::::...:::. :..... . : . .
XP_005 --TTSCGSLAYSAPEILLGDEYDAPAVDIWSLGVILFMLVCGQPPFQEANDSETLTMIMD
180 190 200 210 220
240 250 260 270 280
pF1KB8 HRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQ--PPKPKATSSASFKRE
. : .... :::::: :::: : ..: ..:: .: ::: :.:
XP_005 CKYTVP--SHVSKECKDLITRMLQRDPKRRASLEEIENHPWLQGVDPSPATKYNIPLVSY
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB8 GEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAKDHHI
XP_005 KNLSEEEHNSIIQRMVLGDIADRDAIVEALETNRYNHITATYFLLAERILREKQEKEIQT
290 300 310 320 330 340
>>XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtubule (643 aa)
initn: 530 init1: 275 opt: 630 Z-score: 281.5 bits: 61.5 E(85289): 6.1e-09
Smith-Waterman score: 630; 40.3% identity (70.5% similar) in 258 aa overlap (18-272:62-307)
10 20 30 40
pF1KB8 MDDATVLRKKGYIVGINLGKGSYAKVKSAYSERLKFNVAVKIIDRKK
.:::..:::: : .::.::::. .
XP_005 TSRSGARCRNSIASCADEQPHIGNYRLLKTIGKGNFAKVKLARHILTGREVAIKIIDKTQ
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB8 -TPTDFVERFLPREMDILATVNHGSIIKTYEIFETSDGRIYIIMELGVQGDLLEFIKCQG
.::.. . : ::. :. .:: .:.: .:..:: . .:.::: . :...... .:
XP_005 LNPTSLQKLF--REVRIMKILNHPNIVKLFEVIET-EKTLYLIMEYASGGEVFDYLVAHG
100 110 120 130 140
110 120 130 140 150 160
pF1KB8 ALHEDVARKMFRQLSSAVKYCHDLDIVHRDLKCENLLLDKDFNIKLSDFGFSKRCLRDSN
..: ::. :::. :::.:::. ::::::: :::::: :.:::..:::::.. .
XP_005 RMKEKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFT--VG
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 GRIILSKTFCGSAAYAAPEVLQSIPYQPKVYDIWSLGVILYIMVCGSMPYDDSDIRKML-
:.. ::::: :::::..:. :. :.:::::::: .: ::.:.: ......
XP_005 GKL---DTFCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSLPFDGQNLKELRE
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB8 RIQK-EHRVDFPRSKNLTCECKDLIYRMLQPDVSQRLHIDEILSHSWLQPPKPKATSSAS
:. . ..:. : .. .:..:. :.: . .: ...:.. :.
XP_005 RVLRGKYRIPF----YMSTDCENLLKRFLVLNPIKRGTLEQIMKDRWINAGHEEDELKPF
270 280 290 300 310
290 300 310 320 330 340
pF1KB8 FKREGEGKYRAECKLDTKTGLRPDHRPDHKLGAKTQHRLLVVPENENRMEDRLAETSRAK
XP_005 VEPELDISDQKRIDIMVGMGYSQEEIQESLSKMKYDEITATYLLLGRKSSELDASDSSSS
320 330 340 350 360 370
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:58:29 2016 done: Fri Nov 4 14:58:30 2016
Total Scan time: 8.100 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]