Result of FASTA (omim) for
pFN21AB8694
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8694, 455 aa
1>>>pF1KB8694 455 - 455 aa - 455 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4839+/-0.000462; mu= 16.8742+/- 0.028
mean_var=75.2866+/-14.709, 0's: 0 Z-trim(110.3): 163 B-trim: 18 in 1/53
Lambda= 0.147814
statistics sampled from 18442 (18626) to 18442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.578), E-opt: 0.2 (0.218), width: 16
Scan time: 7.770
The best scores are: opt bits E(85289)
NP_057439 (OMIM: 615428) probable ATP-dependent RN ( 455) 2918 632.2 8.6e-181
NP_957518 (OMIM: 615428) probable ATP-dependent RN ( 406) 1595 350.0 6.7e-96
NP_060365 (OMIM: 616621) probable ATP-dependent RN ( 796) 913 204.8 7e-52
NP_004389 (OMIM: 601235) probable ATP-dependent RN ( 875) 768 173.9 1.5e-42
NP_055555 (OMIM: 268305,608546) eukaryotic initiat ( 411) 759 171.8 3.1e-42
NP_006764 (OMIM: 606355) ATP-dependent RNA helicas ( 670) 758 171.7 5.4e-42
XP_016879601 (OMIM: 613369) PREDICTED: ATP-depende ( 775) 753 170.7 1.3e-41
XP_016879600 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 753 170.7 1.5e-41
XP_006721720 (OMIM: 613369) PREDICTED: ATP-depende ( 938) 753 170.7 1.5e-41
NP_987095 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 753 170.7 1.5e-41
NP_031398 (OMIM: 613369) ATP-dependent RNA helicas ( 938) 753 170.7 1.5e-41
XP_011522561 (OMIM: 613369) PREDICTED: ATP-depende ( 674) 745 168.9 3.7e-41
XP_005271474 (OMIM: 600326) PREDICTED: probable AT ( 483) 741 168.0 5.1e-41
NP_004388 (OMIM: 600326) probable ATP-dependent RN ( 483) 741 168.0 5.1e-41
NP_001244120 (OMIM: 600326) probable ATP-dependent ( 483) 741 168.0 5.1e-41
NP_006377 (OMIM: 608469) probable ATP-dependent RN ( 729) 742 168.3 6.2e-41
NP_001091974 (OMIM: 608469) probable ATP-dependent ( 731) 742 168.3 6.2e-41
NP_542165 (OMIM: 142560) spliceosome RNA helicase ( 428) 731 165.8 2e-40
NP_004631 (OMIM: 142560) spliceosome RNA helicase ( 428) 731 165.8 2e-40
NP_001958 (OMIM: 601102) eukaryotic initiation fac ( 407) 718 163.0 1.3e-39
NP_004387 (OMIM: 180630) probable ATP-dependent RN ( 614) 720 163.6 1.4e-39
NP_001307524 (OMIM: 180630) probable ATP-dependent ( 614) 720 163.6 1.4e-39
NP_001307525 (OMIM: 180630) probable ATP-dependent ( 614) 720 163.6 1.4e-39
NP_001307526 (OMIM: 180630) probable ATP-dependent ( 614) 720 163.6 1.4e-39
NP_076977 (OMIM: 611665) ATP-dependent RNA helicas ( 881) 715 162.6 3.9e-39
NP_001104792 (OMIM: 611665) ATP-dependent RNA heli ( 882) 715 162.6 3.9e-39
XP_016866492 (OMIM: 606286) PREDICTED: probable AT ( 439) 704 160.1 1.1e-38
XP_011534229 (OMIM: 606286) PREDICTED: probable AT ( 529) 704 160.1 1.3e-38
XP_011534230 (OMIM: 606286) PREDICTED: probable AT ( 529) 704 160.1 1.3e-38
XP_011534228 (OMIM: 606286) PREDICTED: probable AT ( 604) 704 160.1 1.5e-38
NP_061135 (OMIM: 606286) probable ATP-dependent RN ( 648) 704 160.2 1.5e-38
NP_001407 (OMIM: 602641) eukaryotic initiation fac ( 406) 698 158.7 2.6e-38
XP_016857921 (OMIM: 174300,615464) PREDICTED: prob ( 619) 698 158.9 3.6e-38
XP_011508337 (OMIM: 174300,615464) PREDICTED: prob ( 619) 698 158.9 3.6e-38
NP_001026895 (OMIM: 174300,615464) probable ATP-de ( 619) 698 158.9 3.6e-38
XP_016857920 (OMIM: 174300,615464) PREDICTED: prob ( 619) 698 158.9 3.6e-38
NP_001307110 (OMIM: 174300,615464) probable ATP-de ( 567) 615 141.1 7.2e-33
XP_016884803 (OMIM: 300160,300958) PREDICTED: ATP- ( 475) 614 140.9 7.2e-33
XP_006711625 (OMIM: 174300,615464) PREDICTED: prob ( 557) 614 140.9 8.2e-33
NP_001289481 (OMIM: 400010,415000) ATP-dependent R ( 657) 614 141.0 9.4e-33
NP_001116137 (OMIM: 400010,415000) ATP-dependent R ( 660) 614 141.0 9.4e-33
NP_004651 (OMIM: 400010,415000) ATP-dependent RNA ( 660) 614 141.0 9.4e-33
NP_001180345 (OMIM: 300160,300958) ATP-dependent R ( 661) 614 141.0 9.4e-33
XP_016884802 (OMIM: 300160,300958) PREDICTED: ATP- ( 476) 608 139.6 1.7e-32
NP_001180346 (OMIM: 300160,300958) ATP-dependent R ( 646) 608 139.7 2.2e-32
NP_001347 (OMIM: 300160,300958) ATP-dependent RNA ( 662) 608 139.7 2.3e-32
XP_011542194 (OMIM: 300160,300958) PREDICTED: ATP- ( 598) 607 139.4 2.4e-32
NP_001278405 (OMIM: 612500) probable ATP-dependent ( 491) 591 136.0 2.2e-31
XP_011522534 (OMIM: 612500) PREDICTED: probable AT ( 581) 591 136.0 2.5e-31
NP_008941 (OMIM: 612500) probable ATP-dependent RN ( 599) 591 136.0 2.6e-31
>>NP_057439 (OMIM: 615428) probable ATP-dependent RNA he (455 aa)
initn: 2918 init1: 2918 opt: 2918 Z-score: 3366.7 bits: 632.2 E(85289): 8.6e-181
Smith-Waterman score: 2918; 99.8% identity (99.8% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GRDIIGLAETGPGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
370 380 390 400 410 420
430 440 450
pF1KB8 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
:::::::::::::::::::::::::::::::::::
NP_057 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
430 440 450
>>NP_957518 (OMIM: 615428) probable ATP-dependent RNA he (406 aa)
initn: 1587 init1: 1587 opt: 1595 Z-score: 1842.7 bits: 350.0 E(85289): 6.7e-96
Smith-Waterman score: 2487; 89.0% identity (89.0% similar) in 455 aa overlap (1-455:1-406)
10 20 30 40 50 60
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_957 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 GRDIIGLAETGPGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_957 GRDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_957 VQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRIL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_957 NMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVSSKYQTVEKLQQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 YYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQS
:::::::::: :
NP_957 YYIFIPSKFK-------------------------------------------------S
250
310 320 330 340 350 360
pF1KB8 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_957 KRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRS
260 270 280 290 300 310
370 380 390 400 410 420
pF1KB8 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_957 GKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQRFARMELREHGEK
320 330 340 350 360 370
430 440 450
pF1KB8 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
:::::::::::::::::::::::::::::::::::
NP_957 KKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
380 390 400
>>NP_060365 (OMIM: 616621) probable ATP-dependent RNA he (796 aa)
initn: 908 init1: 401 opt: 913 Z-score: 1052.4 bits: 204.8 E(85289): 7e-52
Smith-Waterman score: 913; 37.2% identity (69.3% similar) in 417 aa overlap (21-431:215-631)
10 20 30 40 50
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKI
.:. .:.:.... : .: .:. .:: :
NP_060 KADTLKVKDRKKKKKKGQEAGGFFEDASQYDENLSFQDMNLSRPLLKAITAMGFKQPTPI
190 200 210 220 230 240
60 70 80 90 100
pF1KB8 QIEAIPLALQGRDIIGLAETGPGKTGAFALPILNALLETPQR---LFALVLTPTRELAFQ
: ::..: :.:: . : :: :::.:::::.:. :. :.. .:::.:::::..:
NP_060 QKACIPVGLLGKDICACAATGTGKTAAFALPVLERLIYKPRQAPVTRVLVLVPTRELGIQ
250 260 270 280 290 300
110 120 130 140 150 160
pF1KB8 ISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRA
. . :.. .. . . :::.: :: :: : :.:::::::::::.: .:.: .
NP_060 VHSVTRQLAQFCNITTCLAVGGLDVKSQEAALRAAPDILIATPGRLIDHLHNCPSFHLSS
310 320 330 340 350 360
170 180 190 200 210 220
pF1KB8 LKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCA
.. :..:::::.:. :: .. .:... . :.:.::::::: .:. : ..:::::.
NP_060 IEVLILDEADRMLDEYFEEQMKEIIRMCSHHRQTMLFSATMTDEVKDLASVSLKNPVRIF
370 380 390 400 410 420
230 240 250 260 270 280
pF1KB8 VSSKYQTVEKLQQYYIFI-PSKFKDTYLVY--ILNELAGNSFMIFCSTCNNTQRTALLLR
:.:. ... :.: .: : :.. : . .:.. . :.: .: ....: .::
NP_060 VNSNTDVAPFLRQEFIRIRPNREGDREAIVAALLTRTFTDHVMLFTQTKKQAHRMHILLG
430 440 450 460 470 480
290 300 310 320 330 340
pF1KB8 NLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHS
.:. . :::..::..:: .: .:: . .::.:::::.::::: : .:.:: .:.
NP_060 LMGLQVGELHGNLSQTQRLEALRRFKDEQIDILVATDVAARGLDIEGVKTVINFTMPNTI
490 500 510 520 530 540
350 360 370 380 390 400
pF1KB8 KDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVA
: :.:::::::::::.:.....: . . .....: . . . .: .. . ...
NP_060 KHYVHRVGRTARAGRAGRSVSLVGEDERKMLKEIVKAAKAPVKARILPQDVILKFRDKIE
550 560 570 580 590 600
410 420 430 440 450
pF1KB8 EAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
. .. . :. ..:.:. .. .: :
NP_060 KMEKDVYAVLQLEAEEKEMQQSEAQINTAKRLLEKGKEAVVQEPERSWFQTKEERKKEKI
610 620 630 640 650 660
>>NP_004389 (OMIM: 601235) probable ATP-dependent RNA he (875 aa)
initn: 709 init1: 264 opt: 768 Z-score: 884.7 bits: 173.9 E(85289): 1.5e-42
Smith-Waterman score: 768; 33.9% identity (65.9% similar) in 416 aa overlap (18-425:63-469)
10 20 30 40
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKP
.. .: :.:. .. .. .. .
NP_004 KKKQLRKQLKKPEWQVERESISRLMQNYEKINVNEITRFSDFPLSKKTLKGLQEAQYRLV
40 50 60 70 80 90
50 60 70 80 90 100
pF1KB8 TKIQIEAIPLALQGRDIIGLAETGPGKTGAFALPILNALLE----TPQRLFALVLTPTRE
:.:: ..: :::::.:..: :.:: ::: :: .:.:.:: . . . : .:...::::
NP_004 TEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEALYRLQWTSTDGLGVLIISPTRE
100 110 120 130 140 150
110 120 130 140 150 160
pF1KB8 LAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGF
::.: : .. .:.. ....:.:: : ... .. .:.. :::::..:...: .:
NP_004 LAYQTFEVLRKVGKNHDFSAGLIIGGKD-LKHEAERINNINILVCTPGRLLQHMDETVSF
160 170 180 190 200 210
170 180 190 200 210 220
pF1KB8 NLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNP
. :..::.:::::::.: : .. ... .:. :.:.:::::.::.:. : : .::::
NP_004 HATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQTLLFSATQTKSVKDLARLSLKNP
220 230 240 250 260 270
230 240 250 260 270 280
pF1KB8 VKCAV--SSKYQTVEKLQQYYIFIPSKFKDTYLVYILNELAGNSFMIFCSTCNNTQRTAL
: ..::.: :.: :: . : . : .: .. ..: :.:...:
NP_004 EYVWVHEKAKYSTPATLEQNYIVCELQQKISVLYSFLRSHLKKKSIVFFSSCKEVQYLYR
280 290 300 310 320 330
290 300 310 320 330
pF1KB8 LLRNL--GFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFD
.. : : . . :::...: .:. :.: : ..:.:::.:.::::.: :. :..::
NP_004 VFCRLRPGVSILALHGRQQQMRRMEVYNEFVRKRAAVLFATDIAARGLDFPAVNWVLQFD
340 350 360 370 380 390
340 350 360 370 380 390
pF1KB8 IPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMML
: .. ::::.::::: ..:.:. .. . . :. :. ::.: :. .
NP_004 CPEDANTYIHRAGRTARYKEDGEALLILLPSEKAMVQQ---LLQKKVP-----VKEIKIN
400 410 420 430 440
400 410 420 430 440 450
pF1KB8 TERVAEAQRFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
:.. ..:. . : . . :.:..
NP_004 PEKLIDVQKKLESILAQDQDLKERAQRCFVSYVRSVYLMKDKEVFDVSKLPIPEYALSLG
450 460 470 480 490 500
>>NP_055555 (OMIM: 268305,608546) eukaryotic initiation (411 aa)
initn: 639 init1: 531 opt: 759 Z-score: 879.1 bits: 171.8 E(85289): 3.1e-42
Smith-Waterman score: 759; 31.9% identity (68.4% similar) in 373 aa overlap (19-390:33-404)
10 20 30 40
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPT
: . : :: .:. . : .. :. ::.
NP_055 TTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPS
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB8 KIQIEAIPLALQGRDIIGLAETGPGKTGAFALPILNALLETPQRLFALVLTPTRELAFQI
:: .:: ..:::.:. ...: :::..:.. .:. : .. ::.:.:::::: ::
NP_055 AIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQI
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB8 SEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRAL
.. . :::. ..:: . .:: . . : :.. .::::..: .. ... ::.
NP_055 QKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 KYLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV
:.::.::::..:: :. .. . . .: .. :.:::. ... .. . .:.. :
NP_055 KMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILV
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB8 SSKYQTVEKLQQYYIFIPSK-FKDTYLVYILNELAGNSFMIFCSTCNNTQRTALLLRNLG
. :.: ..:... . . .: : . . :. .. .:::.: ... . .:. .
NP_055 KRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREAN
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB8 FTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSKDY
::. .::.: :..: . ...:.. : .:..::: .::::.:.:....:.:.:.. . :
NP_055 FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELY
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB8 IHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAEAQ
:::.::..: ::.: ::.:: . :..... ::. . .. .:
NP_055 IHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI
370 380 390 400 410
410 420 430 440 450
pF1KB8 RFARMELREHGEKKKRSREDAGDNDDTEGAIGVRNKVAGGKMKKRKGR
>>NP_006764 (OMIM: 606355) ATP-dependent RNA helicase DD (670 aa)
initn: 778 init1: 356 opt: 758 Z-score: 874.9 bits: 171.7 E(85289): 5.4e-42
Smith-Waterman score: 760; 34.7% identity (64.8% similar) in 458 aa overlap (4-442:154-603)
10 20 30
pF1KB8 MAAPEEHDSPTEA-SQPI--VEEEETKTFKDLG
:.. .. .:. : :. . : .: .:
NP_006 DTKKAKTENKGKSEEESAETTKETENNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLC
130 140 150 160 170 180
40 50 60 70 80
pF1KB8 --VTDVLCEACDQLGWTKPTKIQIEAI-PLALQGRDIIGLAETGPGKTGAFALPILNALL
:.. .: ..:.:. :.:: ..: :: :.:::... :.:: ::: :: .: .. ..
NP_006 NLVNENTLKAIKEMGFTNMTEIQHKSIRPL-LEGRDLLAAAKTGSGKTLAFLIPAVELIV
190 200 210 220 230 240
90 100 110 120 130 140
pF1KB8 ET---PQR-LFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKP
. :. .:.:.::::::.: .. : . ..:.:: . ... :..
NP_006 KLRFMPRNGTGVLILSPTRELAMQTFGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGI
250 260 270 280 290 300
150 160 170 180 190 200
pF1KB8 HIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRDRKTFL
.::.::::::.::..:: :: . :. ::.:::::::.. :: :. .:.:..: :.:.:
NP_006 NIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTML
310 320 330 340 350 360
210 220 230 240 250 260
pF1KB8 FSATMTKKVQKLQRAALKN-PVKCAVSSKYQ--TVEKLQQYYIFIPSKFKDTYLVYILNE
::::.:.::. : : .::. :. .:.. ::. :.: :. ::. . : .:..
NP_006 FSATQTRKVEDLARISLKKEPLYVGVDDDKANATVDGLEQGYVVCPSEKRFLLLFTFLKK
370 380 390 400 410 420
270 280 290 300 310 320
pF1KB8 LAGNSFMIFCSTCNNTQRTALLLRNLGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLAT
...:.: :.: ... :: . . .. .::...:.:: .. .: . :: :
NP_006 NRKKKLMVFFSSCMSVKYHYELLNYIDLPVLAIHGKQKQNKRTTTFFQFCNADSGTLLCT
430 440 450 460 470 480
330 340 350 360 370
pF1KB8 DVASRGLDIPHVDVVVNFDIPTHSKDYIHRVGRTARAGRSGKAITFVTQYDVEL-FQRIE
:::.::::::.:: .:..: : :.:::::::::: : .:.. ... :: : :
NP_006 DVAARGLDIPEVDWIVQYDPPDDPKEYIHRVGRTAR-GLNGRGHALLILRPEELGFLR--
490 500 510 520 530
380 390 400 410 420 430
pF1KB8 HLIGKKLP----GFP-TQDDEVMMLTERVAEAQRFARMELREHGEKKKRSREDAGDNDDT
.: .:.: : .. .... :.. : . : :.. ... .: : :. .
NP_006 YLKQSKVPLSEFDFSWSKISDIQSQLEKLIEKNYF----LHKSAQEAYKSYIRAYDSHSL
540 550 560 570 580 590
440 450
pF1KB8 EGAIGVRNKVAGGKMKKRKGR
. ..: :
NP_006 KQIFNVNNLNLPQVALSFGFKVPPFVDLNVNSNEGKQKKRGGGGGFGYQKTKKVEKSKIF
600 610 620 630 640 650
>>XP_016879601 (OMIM: 613369) PREDICTED: ATP-dependent R (775 aa)
initn: 750 init1: 252 opt: 753 Z-score: 868.2 bits: 170.7 E(85289): 1.3e-41
Smith-Waterman score: 753; 37.9% identity (68.3% similar) in 356 aa overlap (25-371:91-443)
10 20 30 40 50
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEA
.: .: . : . . .:.:: :: ..
XP_016 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQG
70 80 90 100 110 120
60 70 80 90 100
pF1KB8 IPLALQGRDIIGLAETGPGKTGAFALPILNAL-----LETPQRLFALVLTPTRELAFQIS
.:.::.:::.::.:.:: :::.:: :.: . :: . .:... ::::: ::
XP_016 VPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIH
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB8 EQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALK
. . .:.. ...:... :: . :. :: . .:.. ::::::::... :. ::. ..
XP_016 AECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVS
190 200 210 220 230
170 180 190 200 210 220
pF1KB8 YLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVS
:::.:::::...: :: .: .: . . ::.:.:::::. ::..:: : : .:.. . .
XP_016 YLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQG
240 250 260 270 280 290
230 240 250 260 270 280
pF1KB8 SKYQTVEKLQQYYIFI---PSKFKDTYLVYILNELAGN-SFMIFCSTCNNTQRTALLLRN
. .. : . : .. :::. ..:. : :.... : ..: . :... : :..
XP_016 DIGEANEDVTQIVEILHSGPSKW--NWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ
300 310 320 330 340 350
290 300 310 320 330 340
pF1KB8 LGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSK
: . :::.:.::.: .. :: : .:.:::::.:::::: . .:.:.:.
XP_016 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID
360 370 380 390 400 410
350 360 370 380 390 400
pF1KB8 DYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAE
. ::.:::.:::..: : :..: :
XP_016 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK
420 430 440 450 460 470
>>XP_016879600 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa)
initn: 716 init1: 252 opt: 753 Z-score: 867.0 bits: 170.7 E(85289): 1.5e-41
Smith-Waterman score: 753; 37.9% identity (68.3% similar) in 356 aa overlap (25-371:254-606)
10 20 30 40 50
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEA
.: .: . : . . .:.:: :: ..
XP_016 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQG
230 240 250 260 270 280
60 70 80 90 100
pF1KB8 IPLALQGRDIIGLAETGPGKTGAFALPILNAL-----LETPQRLFALVLTPTRELAFQIS
.:.::.:::.::.:.:: :::.:: :.: . :: . .:... ::::: ::
XP_016 VPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIH
290 300 310 320 330 340
110 120 130 140 150 160
pF1KB8 EQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALK
. . .:.. ...:... :: . :. :: . .:.. ::::::::... :. ::. ..
XP_016 AECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVS
350 360 370 380 390 400
170 180 190 200 210 220
pF1KB8 YLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVS
:::.:::::...: :: .: .: . . ::.:.:::::. ::..:: : : .:.. . .
XP_016 YLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQG
410 420 430 440 450 460
230 240 250 260 270 280
pF1KB8 SKYQTVEKLQQYYIFI---PSKFKDTYLVYILNELAGN-SFMIFCSTCNNTQRTALLLRN
. .. : . : .. :::. ..:. : :.... : ..: . :... : :..
XP_016 DIGEANEDVTQIVEILHSGPSKW--NWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ
470 480 490 500 510 520
290 300 310 320 330 340
pF1KB8 LGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSK
: . :::.:.::.: .. :: : .:.:::::.:::::: . .:.:.:.
XP_016 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID
530 540 550 560 570 580
350 360 370 380 390 400
pF1KB8 DYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAE
. ::.:::.:::..: : :..: :
XP_016 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK
590 600 610 620 630 640
>>XP_006721720 (OMIM: 613369) PREDICTED: ATP-dependent R (938 aa)
initn: 716 init1: 252 opt: 753 Z-score: 867.0 bits: 170.7 E(85289): 1.5e-41
Smith-Waterman score: 753; 37.9% identity (68.3% similar) in 356 aa overlap (25-371:254-606)
10 20 30 40 50
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEA
.: .: . : . . .:.:: :: ..
XP_006 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQG
230 240 250 260 270 280
60 70 80 90 100
pF1KB8 IPLALQGRDIIGLAETGPGKTGAFALPILNAL-----LETPQRLFALVLTPTRELAFQIS
.:.::.:::.::.:.:: :::.:: :.: . :: . .:... ::::: ::
XP_006 VPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIH
290 300 310 320 330 340
110 120 130 140 150 160
pF1KB8 EQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALK
. . .:.. ...:... :: . :. :: . .:.. ::::::::... :. ::. ..
XP_006 AECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVS
350 360 370 380 390 400
170 180 190 200 210 220
pF1KB8 YLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVS
:::.:::::...: :: .: .: . . ::.:.:::::. ::..:: : : .:.. . .
XP_006 YLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQG
410 420 430 440 450 460
230 240 250 260 270 280
pF1KB8 SKYQTVEKLQQYYIFI---PSKFKDTYLVYILNELAGN-SFMIFCSTCNNTQRTALLLRN
. .. : . : .. :::. ..:. : :.... : ..: . :... : :..
XP_006 DIGEANEDVTQIVEILHSGPSKW--NWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ
470 480 490 500 510 520
290 300 310 320 330 340
pF1KB8 LGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSK
: . :::.:.::.: .. :: : .:.:::::.:::::: . .:.:.:.
XP_006 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID
530 540 550 560 570 580
350 360 370 380 390 400
pF1KB8 DYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAE
. ::.:::.:::..: : :..: :
XP_006 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK
590 600 610 620 630 640
>>NP_987095 (OMIM: 613369) ATP-dependent RNA helicase DD (938 aa)
initn: 716 init1: 252 opt: 753 Z-score: 867.0 bits: 170.7 E(85289): 1.5e-41
Smith-Waterman score: 753; 37.9% identity (68.3% similar) in 356 aa overlap (25-371:254-606)
10 20 30 40 50
pF1KB8 MAAPEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEA
.: .: . : . . .:.:: :: ..
NP_987 ITNLTPQQLIDLRHKLNLRVSGAAPPRPGSSFAHFGFDEQLMHQIRKSEYTQPTPIQCQG
230 240 250 260 270 280
60 70 80 90 100
pF1KB8 IPLALQGRDIIGLAETGPGKTGAFALPILNAL-----LETPQRLFALVLTPTRELAFQIS
.:.::.:::.::.:.:: :::.:: :.: . :: . .:... ::::: ::
NP_987 VPVALSGRDMIGIAKTGSGKTAAFIWPMLIHIMDQKELEPGDGPIAVIVCPTRELCQQIH
290 300 310 320 330 340
110 120 130 140 150 160
pF1KB8 EQFEALGSSIGVQSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALK
. . .:.. ...:... :: . :. :: . .:.. ::::::::... :. ::. ..
NP_987 AECKRFGKAYNLRSVAVYGGGSMWEQAKALQEGAEIVVCTPGRLIDHVKK-KATNLQRVS
350 360 370 380 390 400
170 180 190 200 210 220
pF1KB8 YLVMDEADRILNMDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAVS
:::.:::::...: :: .: .: . . ::.:.:::::. ::..:: : : .:.. . .
NP_987 YLVFDEADRMFDMGFEYQVRSIASHVRPDRQTLLFSATFRKKIEKLARDILIDPIRVVQG
410 420 430 440 450 460
230 240 250 260 270 280
pF1KB8 SKYQTVEKLQQYYIFI---PSKFKDTYLVYILNELAGN-SFMIFCSTCNNTQRTALLLRN
. .. : . : .. :::. ..:. : :.... : ..: . :... : :..
NP_987 DIGEANEDVTQIVEILHSGPSKW--NWLTRRLVEFTSSGSVLLFVTKKANAEELANNLKQ
470 480 490 500 510 520
290 300 310 320 330 340
pF1KB8 LGFTAIPLHGQMSQSKRLGSLNKFKAKARSILLATDVASRGLDIPHVDVVVNFDIPTHSK
: . :::.:.::.: .. :: : .:.:::::.:::::: . .:.:.:.
NP_987 EGHNLGLLHGDMDQSERNKVISDFKKKDIPVLVATDVAARGLDIPSIKTVINYDVARDID
530 540 550 560 570 580
350 360 370 380 390 400
pF1KB8 DYIHRVGRTARAGRSGKAITFVTQYDVELFQRIEHLIGKKLPGFPTQDDEVMMLTERVAE
. ::.:::.:::..: : :..: :
NP_987 THTHRIGRTGRAGEKGVAYTLLTPKDSNFAGDLVRNLEGANQHVSKELLDLAMQNAWFRK
590 600 610 620 630 640
455 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:40:30 2016 done: Fri Nov 4 14:40:31 2016
Total Scan time: 7.770 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]