Result of FASTA (omim) for
pFN21AB8689
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8689, 450 aa
1>>>pF1KB8689 450 - 450 aa - 450 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0986+/-0.000322; mu= 19.4974+/- 0.020
mean_var=71.0887+/-14.381, 0's: 0 Z-trim(116.1): 21 B-trim: 0 in 0/54
Lambda= 0.152116
statistics sampled from 27002 (27023) to 27002 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.317), width: 16
Scan time: 9.660
The best scores are: opt bits E(85289)
NP_064596 (OMIM: 607362) repulsive guidance molecu ( 450) 3089 686.9 2.9e-197
NP_001159755 (OMIM: 607362) repulsive guidance mol ( 458) 3055 679.4 5.1e-195
NP_001159759 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
NP_001159761 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
NP_001159760 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
NP_001159758 (OMIM: 607362) repulsive guidance mol ( 434) 2972 661.2 1.5e-189
XP_011541648 (OMIM: 612687) PREDICTED: RGM domain ( 396) 1307 295.8 1.4e-79
XP_005272023 (OMIM: 612687) PREDICTED: RGM domain ( 477) 1307 295.9 1.6e-79
XP_011541647 (OMIM: 612687) PREDICTED: RGM domain ( 478) 1307 295.9 1.6e-79
XP_016864880 (OMIM: 612687) PREDICTED: RGM domain ( 478) 1307 295.9 1.6e-79
XP_016864879 (OMIM: 612687) PREDICTED: RGM domain ( 478) 1307 295.9 1.6e-79
NP_001012779 (OMIM: 612687) RGM domain family memb ( 478) 1307 295.9 1.6e-79
NP_998818 (OMIM: 602390,608374) hemojuvelin isofor ( 426) 1002 228.9 2.1e-59
XP_005272989 (OMIM: 602390,608374) PREDICTED: hemo ( 426) 1002 228.9 2.1e-59
NP_660320 (OMIM: 602390,608374) hemojuvelin isofor ( 313) 779 179.8 8.7e-45
XP_011541649 (OMIM: 612687) PREDICTED: RGM domain ( 273) 632 147.5 4e-35
NP_973733 (OMIM: 602390,608374) hemojuvelin isofor ( 200) 366 89.1 1.2e-17
NP_998817 (OMIM: 602390,608374) hemojuvelin isofor ( 200) 366 89.1 1.2e-17
NP_001303696 (OMIM: 602390,608374) hemojuvelin iso ( 200) 366 89.1 1.2e-17
>>NP_064596 (OMIM: 607362) repulsive guidance molecule A (450 aa)
initn: 3089 init1: 3089 opt: 3089 Z-score: 3662.6 bits: 686.9 E(85289): 2.9e-197
Smith-Waterman score: 3089; 100.0% identity (100.0% similar) in 450 aa overlap (1-450:1-450)
10 20 30 40 50 60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
370 380 390 400 410 420
430 440 450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
::::::::::::::::::::::::::::::
NP_064 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
430 440 450
>>NP_001159755 (OMIM: 607362) repulsive guidance molecul (458 aa)
initn: 3055 init1: 3055 opt: 3055 Z-score: 3622.1 bits: 679.4 E(85289): 5.1e-195
Smith-Waterman score: 3055; 100.0% identity (100.0% similar) in 446 aa overlap (5-450:13-458)
10 20 30 40 50
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILK
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGGLGPRRAGTSRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 CNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNSEFWSATSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQ
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 HNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HNCSKDGPTSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLR
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 TFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFTDRFQTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 QAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEMDELPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTF
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 AVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVRMPEEVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 ETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPYETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLH
370 380 390 400 410 420
420 430 440 450
pF1KB8 LYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
::::::::::::::::::::::::::::::::::::::
NP_001 LYERTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
430 440 450
>>NP_001159759 (OMIM: 607362) repulsive guidance molecul (434 aa)
initn: 2972 init1: 2972 opt: 2972 Z-score: 3524.0 bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)
10 20 30 40 50 60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
10 20 30 40
70 80 90 100 110 120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
350 360 370 380 390 400
430 440 450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
410 420 430
>>NP_001159761 (OMIM: 607362) repulsive guidance molecul (434 aa)
initn: 2972 init1: 2972 opt: 2972 Z-score: 3524.0 bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)
10 20 30 40 50 60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
10 20 30 40
70 80 90 100 110 120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
350 360 370 380 390 400
430 440 450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
410 420 430
>>NP_001159760 (OMIM: 607362) repulsive guidance molecul (434 aa)
initn: 2972 init1: 2972 opt: 2972 Z-score: 3524.0 bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)
10 20 30 40 50 60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
10 20 30 40
70 80 90 100 110 120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
350 360 370 380 390 400
430 440 450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
410 420 430
>>NP_001159758 (OMIM: 607362) repulsive guidance molecul (434 aa)
initn: 2972 init1: 2972 opt: 2972 Z-score: 3524.0 bits: 661.2 E(85289): 1.5e-189
Smith-Waterman score: 2972; 100.0% identity (100.0% similar) in 434 aa overlap (17-450:1-434)
10 20 30 40 50 60
pF1KB8 MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSA
10 20 30 40
70 80 90 100 110 120
pF1KB8 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSGSHAPASDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGP
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSQPRLRTLPPAGDSQERSDSPEICHYEKSFHKHSATPNYTHCGLFGDPHLRTFTDRFQT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELP
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEV
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETA
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDL
350 360 370 380 390 400
430 440 450
pF1KB8 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
::::::::::::::::::::::::::::::
NP_001 PGRAAAGLPLAPRPLLGALVPLLALLPVFC
410 420 430
>>XP_011541648 (OMIM: 612687) PREDICTED: RGM domain fami (396 aa)
initn: 1137 init1: 525 opt: 1307 Z-score: 1549.8 bits: 295.8 E(85289): 1.4e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:7-384)
10 20 30 40 50 60
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
:. :: :.: ::...: : :: .. .
XP_011 MPPNCDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
10 20 30
70 80 90 100 110 120
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
. ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::
XP_011 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
40 50 60 70 80
130 140 150 160 170
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
: .::. : ..:.:... :.: :::::::::::: : :
XP_011 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
90 100 110 120 130
180 190 200 210 220 230
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
:::::.:::::::::::.:::::.::.:::.::::.:.::::: .::.::::::: :.
XP_011 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
140 150 160 170 180 190
240 250 260 270 280 290
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
::::::::. .:::. :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_011 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
200 210 220 230 240 250
300 310 320 330 340 350
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
... . : .:: : ::. ::::...:: ...: . :. . : . ...:
XP_011 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
260 270 280 290 300
360 370 380 390 400 410
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. :: :.. :..
XP_011 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
310 320 330 340 350 360
420 430 440 450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
. . :... : ..
XP_011 SSGNGTPRGGSDLSVSLGLTCLILIVFL
370 380 390
>>XP_005272023 (OMIM: 612687) PREDICTED: RGM domain fami (477 aa)
initn: 1137 init1: 525 opt: 1307 Z-score: 1548.7 bits: 295.9 E(85289): 1.6e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:88-465)
10 20 30 40 50 60
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
:. :: :.: ::...: : :: .. .
XP_005 EQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
60 70 80 90 100 110
70 80 90 100 110 120
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
. ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::
XP_005 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
120 130 140 150 160
130 140 150 160 170
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
: .::. : ..:.:... :.: :::::::::::: : :
XP_005 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
170 180 190 200 210
180 190 200 210 220 230
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
:::::.:::::::::::.:::::.::.:::.::::.:.::::: .::.::::::: :.
XP_005 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
220 230 240 250 260 270
240 250 260 270 280 290
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
::::::::. .:::. :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_005 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
... . : .:: : ::. ::::...:: ...: . :. . : . ...:
XP_005 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
340 350 360 370 380
360 370 380 390 400 410
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. :: :.. :..
XP_005 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
390 400 410 420 430 440
420 430 440 450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
. . :... : ..
XP_005 SSGNGTPRGGSDLSVSLGLTCLILIVFL
450 460 470
>>XP_011541647 (OMIM: 612687) PREDICTED: RGM domain fami (478 aa)
initn: 1137 init1: 525 opt: 1307 Z-score: 1548.7 bits: 295.9 E(85289): 1.6e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:89-466)
10 20 30 40 50 60
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
:. :: :.: ::...: : :: .. .
XP_011 EQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
60 70 80 90 100 110
70 80 90 100 110 120
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
. ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::
XP_011 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
120 130 140 150 160
130 140 150 160 170
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
: .::. : ..:.:... :.: :::::::::::: : :
XP_011 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
170 180 190 200 210
180 190 200 210 220 230
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
:::::.:::::::::::.:::::.::.:::.::::.:.::::: .::.::::::: :.
XP_011 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
220 230 240 250 260 270
240 250 260 270 280 290
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
::::::::. .:::. :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_011 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
... . : .:: : ::. ::::...:: ...: . :. . : . ...:
XP_011 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. :: :.. :..
XP_011 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
400 410 420 430 440 450
420 430 440 450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
. . :... : ..
XP_011 SSGNGTPRGGSDLSVSLGLTCLILIVFL
460 470
>>XP_016864880 (OMIM: 612687) PREDICTED: RGM domain fami (478 aa)
initn: 1137 init1: 525 opt: 1307 Z-score: 1548.7 bits: 295.9 E(85289): 1.6e-79
Smith-Waterman score: 1331; 51.5% identity (74.1% similar) in 406 aa overlap (39-431:89-466)
10 20 30 40 50 60
pF1KB8 VVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSPCKILKCNSEFWSATSGSHAPA
:. :: :.: ::...: : :: .. .
XP_016 EQRRSPGLCPPPLELLLLLLFSLGLLHAGDCQQPAQ---CRIQKCTTDFVSLTSHLNSAV
60 70 80 90 100 110
70 80 90 100 110 120
pF1KB8 SDDTPEFCAALRSYALCTRRTARTCRGDLAYHSAVHGIEDLMSQHNCSKDGPTSQPRLRT
. ::: :::.:: ::.::...:::.:.::::: :: :::::.:::::::::
XP_016 DGFDSEFCKALRAYAGCTQRTSKACRGNLVYHSAVLGISDLMSQRNCSKDGPTS------
120 130 140 150 160
130 140 150 160 170
pF1KB8 LPPAGDSQERSDSPEICHYEKSFHKHSAT----------PNYTHCGLFGDPHLRTFTDRF
: .::. : ..:.:... :.: :::::::::::: : :
XP_016 ----------STNPEVTHDPCNYHSHAGAREHRRGDQNPPSYLFCGLFGDPHLRTFKDNF
170 180 190 200 210
180 190 200 210 220 230
pF1KB8 QTCKVQGAWPLIDNNYLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDE
:::::.:::::::::::.:::::.::.:::.::::.:.::::: .::.::::::: :.
XP_016 QTCKVEGAWPLIDNNYLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDD
220 230 240 250 260 270
240 250 260 270 280 290
pF1KB8 LPAAFVDGSKNGGDKHGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPE
::::::::. .:::. :.::.:.:. ::..::..:.:::::. :::::::::.:.::::
XP_016 LPAAFVDGTTSGGDSD-AKSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPE
280 290 300 310 320 330
300 310 320 330 340 350
pF1KB8 EVVNAVEDWDSQGLYLCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFP--
... . : .:: : ::. ::::...:: ...: . :. . : . ...:
XP_016 DLAMSYE--ESQDLQLCVNGCPLSERID------DGQGQVSAILGHSLPRTSLVQAWPGY
340 350 360 370 380 390
360 370 380 390 400 410
pF1KB8 -YETAVAKCKEKLPVEDLYYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYE
::: ..:.::.::.:.:.:.::::::::::.::: ::. :::::. :: :.. :..
XP_016 TLETANTQCHEKMPVKDIYFQSCVFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFP
400 410 420 430 440 450
420 430 440 450
pF1KB8 RTRDLPGRAAAGLPLAPRPLLGALVPLLALLPVFC
. . :... : ..
XP_016 SSGNGTPRGGSDLSVSLGLTCLILIVFL
460 470
450 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:36:50 2016 done: Fri Nov 4 14:36:51 2016
Total Scan time: 9.660 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]