Result of FASTA (omim) for
pFN21AB8657
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8657, 454 aa
1>>>pF1KB8657 454 - 454 aa - 454 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2861+/-0.000436; mu= 17.2005+/- 0.027
mean_var=74.3897+/-15.071, 0's: 0 Z-trim(110.8): 115 B-trim: 0 in 0/51
Lambda= 0.148702
statistics sampled from 19067 (19177) to 19067 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.595), E-opt: 0.2 (0.225), width: 16
Scan time: 6.150
The best scores are: opt bits E(85289)
NP_056425 (OMIM: 609225) WD repeat domain phosphoi ( 454) 2982 649.7 4.5e-186
NP_057087 (OMIM: 609225) WD repeat domain phosphoi ( 436) 2705 590.3 3.4e-168
NP_001028690 (OMIM: 609225) WD repeat domain phosp ( 443) 2661 580.9 2.4e-165
NP_001028691 (OMIM: 609225) WD repeat domain phosp ( 425) 2384 521.4 1.8e-147
NP_001028692 (OMIM: 609225) WD repeat domain phosp ( 384) 2208 483.6 3.8e-136
NP_001265228 (OMIM: 609225) WD repeat domain phosp ( 310) 2059 451.6 1.3e-126
XP_006715748 (OMIM: 609225) PREDICTED: WD repeat d ( 310) 2059 451.6 1.3e-126
XP_016867441 (OMIM: 609225) PREDICTED: WD repeat d ( 299) 1738 382.7 7e-106
NP_060453 (OMIM: 609224) WD repeat domain phosphoi ( 446) 1574 347.7 3.8e-95
NP_001307701 (OMIM: 609224) WD repeat domain phosp ( 364) 1367 303.2 7.5e-82
XP_016880297 (OMIM: 609224) PREDICTED: WD repeat d ( 318) 1115 249.1 1.3e-65
NP_062559 (OMIM: 609226) WD repeat domain phosphoi ( 344) 388 93.2 1.2e-18
XP_005256434 (OMIM: 609226) PREDICTED: WD repeat d ( 310) 367 88.6 2.5e-17
XP_016880351 (OMIM: 609226) PREDICTED: WD repeat d ( 226) 322 78.9 1.6e-14
XP_016880352 (OMIM: 609226) PREDICTED: WD repeat d ( 226) 322 78.9 1.6e-14
NP_001025067 (OMIM: 300526,300894) WD repeat domai ( 360) 319 78.4 3.6e-14
NP_009006 (OMIM: 300526,300894) WD repeat domain p ( 361) 319 78.4 3.6e-14
NP_620640 (OMIM: 601787) transcription initiation ( 745) 159 44.3 0.0014
NP_008882 (OMIM: 601787) transcription initiation ( 800) 159 44.3 0.0014
>>NP_056425 (OMIM: 609225) WD repeat domain phosphoinosi (454 aa)
initn: 2982 init1: 2982 opt: 2982 Z-score: 3461.6 bits: 649.7 E(85289): 4.5e-186
Smith-Waterman score: 2982; 100.0% identity (100.0% similar) in 454 aa overlap (1-454:1-454)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
370 380 390 400 410 420
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
NP_056 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
430 440 450
>>NP_057087 (OMIM: 609225) WD repeat domain phosphoinosi (436 aa)
initn: 2851 init1: 2705 opt: 2705 Z-score: 3140.7 bits: 590.3 E(85289): 3.4e-168
Smith-Waterman score: 2819; 96.0% identity (96.0% similar) in 454 aa overlap (1-454:1-436)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::: :::::::::::::::::
NP_057 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS
10 20 30 40
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
350 360 370 380 390 400
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
NP_057 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
410 420 430
>>NP_001028690 (OMIM: 609225) WD repeat domain phosphoin (443 aa)
initn: 2895 init1: 2661 opt: 2661 Z-score: 3089.6 bits: 580.9 E(85289): 2.4e-165
Smith-Waterman score: 2877; 97.6% identity (97.6% similar) in 454 aa overlap (1-454:1-443)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
:::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT
370 380 390 400
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
NP_001 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
410 420 430 440
>>NP_001028691 (OMIM: 609225) WD repeat domain phosphoin (425 aa)
initn: 2764 init1: 2384 opt: 2384 Z-score: 2768.7 bits: 521.4 E(85289): 1.8e-147
Smith-Waterman score: 2714; 93.6% identity (93.6% similar) in 454 aa overlap (1-454:1-425)
10 20 30 40 50 60
pF1KB8 MNLASQSGEAGAGQLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSS
::::::::::::::::::::::::: :::::::::::::::::
NP_001 MNLASQSGEAGAGQLLFANFNQDNT------------------SLAVGSKSGYKFFSLSS
10 20 30 40
70 80 90 100 110 120
pF1KB8 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTIL
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB8 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSAT
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB8 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB8 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLM
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB8 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLD
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB8 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYT
:::::::::::::::::::::::::::::::::::::::::::::: :::
NP_001 PQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK-----------AYT
350 360 370 380 390
430 440 450
pF1KB8 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::
NP_001 DDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
400 410 420
>>NP_001028692 (OMIM: 609225) WD repeat domain phosphoin (384 aa)
initn: 2442 init1: 2208 opt: 2208 Z-score: 2565.2 bits: 483.6 E(85289): 3.8e-136
Smith-Waterman score: 2424; 97.1% identity (97.1% similar) in 383 aa overlap (72-454:13-384)
50 60 70 80 90 100
pF1KB8 VWSLAVGSKSGYKFFSLSSVDKLEQIYECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKV
::::::::::::::::::::::::::::::
NP_001 MFTHVLPFVISADTEDVCIVERLFSSSLVAIVSLKAPRKLKV
10 20 30 40
110 120 130 140 150 160
pF1KB8 CHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CHFKKGTEICNYSYSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGL
50 60 70 80 90 100
170 180 190 200 210 220
pF1KB8 CALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CALSINNDNCYLAYPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATAS
110 120 130 140 150 160
230 240 250 260 270 280
pF1KB8 EKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKGTVIRVFSIPEGQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVK
170 180 190 200 210 220
290 300 310 320 330 340
pF1KB8 EKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKPPEEPTTWTGYFGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQK
230 240 250 260 270 280
350 360 370 380 390 400
pF1KB8 IPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPRLLVGAADGYLYMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYG
290 300 310 320 330 340
410 420 430 440 450
pF1KB8 AAAGKGTYVPSSPTRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::: :::::::::::::::::::::::::::::::::::::
NP_001 AAAGK-----------AYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
350 360 370 380
>>NP_001265228 (OMIM: 609225) WD repeat domain phosphoin (310 aa)
initn: 2059 init1: 2059 opt: 2059 Z-score: 2393.8 bits: 451.6 E(85289): 1.3e-126
Smith-Waterman score: 2059; 100.0% identity (100.0% similar) in 310 aa overlap (145-454:1-310)
120 130 140 150 160 170
pF1KB8 YSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLA
::::::::::::::::::::::::::::::
NP_001 MKVLHTIRETPPNPAGLCALSINNDNCYLA
10 20 30
180 190 200 210 220 230
pF1KB8 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB8 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGY
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB8 FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYL
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB8 YMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSP
220 230 240 250 260 270
420 430 440 450
pF1KB8 TRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::::::::
NP_001 TRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
280 290 300 310
>>XP_006715748 (OMIM: 609225) PREDICTED: WD repeat domai (310 aa)
initn: 2059 init1: 2059 opt: 2059 Z-score: 2393.8 bits: 451.6 E(85289): 1.3e-126
Smith-Waterman score: 2059; 100.0% identity (100.0% similar) in 310 aa overlap (145-454:1-310)
120 130 140 150 160 170
pF1KB8 YSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLA
::::::::::::::::::::::::::::::
XP_006 MKVLHTIRETPPNPAGLCALSINNDNCYLA
10 20 30
180 190 200 210 220 230
pF1KB8 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB8 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGY
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB8 FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYL
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB8 YMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 YMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSP
220 230 240 250 260 270
420 430 440 450
pF1KB8 TRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
::::::::::::::::::::::::::::::::::::::::
XP_006 TRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
280 290 300 310
>>XP_016867441 (OMIM: 609225) PREDICTED: WD repeat domai (299 aa)
initn: 1972 init1: 1738 opt: 1738 Z-score: 2021.8 bits: 382.7 E(85289): 7e-106
Smith-Waterman score: 1954; 96.5% identity (96.5% similar) in 310 aa overlap (145-454:1-299)
120 130 140 150 160 170
pF1KB8 YSNTILAVKLNRQRLIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLA
::::::::::::::::::::::::::::::
XP_016 MKVLHTIRETPPNPAGLCALSINNDNCYLA
10 20 30
180 190 200 210 220 230
pF1KB8 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YPGSATIGEVQVFDTINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPE
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB8 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GQKLFEFRRGVKRCVSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGY
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB8 FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FGKVLMASTSYLPSQVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYL
160 170 180 190 200 210
360 370 380 390 400 410
pF1KB8 YMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSP
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YMYNLDPQEGGECALMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGK--------
220 230 240 250 260
420 430 440 450
pF1KB8 TRLAYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
:::::::::::::::::::::::::::::::::::::
XP_016 ---AYTDDLGAVGGACLEDEASALRLDEDSEHPPMILRTD
270 280 290
>>NP_060453 (OMIM: 609224) WD repeat domain phosphoinosi (446 aa)
initn: 1540 init1: 1499 opt: 1574 Z-score: 1829.2 bits: 347.7 E(85289): 3.8e-95
Smith-Waterman score: 1574; 58.9% identity (84.9% similar) in 411 aa overlap (44-451:28-434)
20 30 40 50 60 70
pF1KB8 QLLFANFNQDNTEVKGASRAAGLGRRAVVWSLAVGSKSGYKFFSLSSVDKLEQIYECTDT
:::.:.:.:::.::::::..:.:.. ..
NP_060 MEAEAADAPPGGVESALSCFSFNQDCTSLATGTKAGYKLFSLSSVEQLDQVHGSNEI
10 20 30 40 50
80 90 100 110 120 130
pF1KB8 EDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQRLIVCL
:: :::::::::::..:: ::...: ::::::::::::::..::...::::::.:::
NP_060 PDVYIVERLFSSSLVVVVSHTKPRQMNVYHFKKGTEICNYSYSSNILSIRLNRQRLLVCL
60 70 80 90 100 110
140 150 160 170 180 190
pF1KB8 EESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFDTINLR
:::.:::::.:::.:.:. . : ::.::::::::..: ::::::: : ::. ..: .:.
NP_060 EESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYDGNSLK
120 130 140 150 160 170
200 210 220 230 240 250
pF1KB8 AANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRCVSICS
.. : ::.. :::..:.:::.:::.::::::::::::.:.::::.:::::.:: :.: :
NP_060 TVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRYVTISS
180 190 200 210 220 230
260 270 280 290 300 310
pF1KB8 LAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPSQVTEM
:.::::..:: :::::::::::::: : .. ::::.::.::.::..::.:.:::.::..:
NP_060 LVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPTQVSDM
240 250 260 270 280 290
320 330 340 350 360 370
pF1KB8 FNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECALMKQH
..: :::::.:: : :..:::.:.::::.:::::....:.:::::::::.::::.:.: :
NP_060 MHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECVLIKTH
300 310 320 330 340 350
380 390 400 410 420 430
pF1KB8 RLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGGACLED
: :: ::.: .. . : . :.:.:.... . . :. : .:..: ::. : . .
NP_060 SLLGS-GTTEE--NKENDLRPSLPQSYAATVARPS-ASSASTVPGYSEDGGALRGEVIPE
360 370 380 390 400 410
440 450
pF1KB8 EASA---LRLDEDSEHPPMILRTD
. : . ::...: ::.::
NP_060 HEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
420 430 440
>>NP_001307701 (OMIM: 609224) WD repeat domain phosphoin (364 aa)
initn: 1333 init1: 1292 opt: 1367 Z-score: 1590.5 bits: 303.2 E(85289): 7.5e-82
Smith-Waterman score: 1367; 58.7% identity (84.8% similar) in 356 aa overlap (99-451:1-352)
70 80 90 100 110 120
pF1KB8 ECTDTEDVCIVERLFSSSLVAIVSLKAPRKLKVCHFKKGTEICNYSYSNTILAVKLNRQR
..: ::::::::::::::..::...:::::
NP_001 MNVYHFKKGTEICNYSYSSNILSIRLNRQR
10 20 30
130 140 150 160 170 180
pF1KB8 LIVCLEESLYIHNIRDMKVLHTIRETPPNPAGLCALSINNDNCYLAYPGSATIGEVQVFD
:.::::::.:::::.:::.:.:. . : ::.::::::::..: ::::::: : ::. ..:
NP_001 LLVCLEESIYIHNIKDMKLLKTLLDIPANPTGLCALSINHSNSYLAYPGSLTSGEIVLYD
40 50 60 70 80 90
190 200 210 220 230 240
pF1KB8 TINLRAANMIPAHDSPLAALAFDASGTKLATASEKGTVIRVFSIPEGQKLFEFRRGVKRC
.:... : ::.. :::..:.:::.:::.::::::::::::.:.::::.:::::.::
NP_001 GNSLKTVCTIAAHEGTLAAITFNASGSKLASASEKGTVIRVFSVPDGQKLYEFRRGMKRY
100 110 120 130 140 150
250 260 270 280 290 300
pF1KB8 VSICSLAFSMDGMFLSASSNTETVHIFKLETVKEKPPEEPTTWTGYFGKVLMASTSYLPS
:.: ::.::::..:: :::::::::::::: : .. ::::.::.::.::..::.:.:::.
NP_001 VTISSLVFSMDSQFLCASSNTETVHIFKLEQVTNSRPEEPSTWSGYMGKMFMAATNYLPT
160 170 180 190 200 210
310 320 330 340 350 360
pF1KB8 QVTEMFNQGRAFATVRLPFCGHKNICSLATIQKIPRLLVGAADGYLYMYNLDPQEGGECA
::..:..: :::::.:: : :..:::.:.::::.:::::....:.:::::::::.::::.
NP_001 QVSDMMHQDRAFATARLNFSGQRNICTLSTIQKLPRLLVASSSGHLYMYNLDPQDGGECV
220 230 240 250 260 270
370 380 390 400 410 420
pF1KB8 LMKQHRLDGSLETTNEILDSASHDCPLVTQTYGAAAGKGTYVPSSPTRLAYTDDLGAVGG
:.: : : :: ::.: .. . : . :.:.:.... . . :. : .:..: ::. :
NP_001 LIKTHSLLGS-GTTEE--NKENDLRPSLPQSYAATVARPS-ASSASTVPGYSEDGGALRG
280 290 300 310 320
430 440 450
pF1KB8 ACLEDEASA---LRLDEDSEHPPMILRTD
. .. : . ::...: ::.::
NP_001 EVIPEHEFATGPVCLDDENEFPPIILCRGNQKGKTKQS
330 340 350 360
454 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:14:16 2016 done: Fri Nov 4 14:14:17 2016
Total Scan time: 6.150 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]