Result of FASTA (ccds) for
pFN21AB8638
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8638, 374 aa
1>>>pF1KB8638 374 - 374 aa - 374 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4159+/-0.000669; mu= 16.0665+/- 0.041
mean_var=66.1039+/-13.789, 0's: 0 Z-trim(110.1): 143 B-trim: 418 in 1/50
Lambda= 0.157747
statistics sampled from 11234 (11396) to 11234 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.35), width: 16
Scan time: 2.720
The best scores are: opt bits E(32554)
CCDS11551.1 SPOP gene_id:8405|Hs108|chr17 ( 374) 2515 580.8 6.4e-166
CCDS33298.1 SPOPL gene_id:339745|Hs108|chr2 ( 392) 1932 448.2 5.8e-126
CCDS34609.1 KLHL7 gene_id:55975|Hs108|chr7 ( 586) 279 72.1 1.4e-12
CCDS3245.2 KLHL6 gene_id:89857|Hs108|chr3 ( 621) 272 70.5 4.6e-12
CCDS5378.2 KLHL7 gene_id:55975|Hs108|chr7 ( 538) 265 68.9 1.2e-11
CCDS47418.1 BTBD9 gene_id:114781|Hs108|chr6 ( 612) 258 67.3 4.1e-11
CCDS30575.1 KLHL21 gene_id:9903|Hs108|chr1 ( 597) 254 66.4 7.5e-11
>>CCDS11551.1 SPOP gene_id:8405|Hs108|chr17 (374 aa)
initn: 2515 init1: 2515 opt: 2515 Z-score: 3092.3 bits: 580.8 E(32554): 6.4e-166
Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 374 aa overlap (1-374:1-374)
10 20 30 40 50 60
pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS11 NAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSHPHLVAEAYRSLASAQ
310 320 330 340 350 360
370
pF1KB8 CPFLGPPRKRLKQS
::::::::::::::
CCDS11 CPFLGPPRKRLKQS
370
>>CCDS33298.1 SPOPL gene_id:339745|Hs108|chr2 (392 aa)
initn: 2177 init1: 1932 opt: 1932 Z-score: 2374.9 bits: 448.2 E(32554): 5.8e-126
Smith-Waterman score: 2144; 80.6% identity (91.6% similar) in 392 aa overlap (1-374:1-392)
10 20 30 40 50 60
pF1KB8 MSRVPSPPPPAEMSSGPVAESWCYTQIKVVKFSYMWTINNFSFCREEMGEVIKSSTFSSG
::: :.:: :..::.::.::::::::.::::::::::::::::::::::::.::::::::
CCDS33 MSREPTPPLPGDMSTGPIAESWCYTQVKVVKFSYMWTINNFSFCREEMGEVLKSSTFSSG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 ANDKLKWCLRVNPKGLDEESKDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQ
.::.::::::::::::.:::::::::::::::::::::::::::.:::: :::::::::
CCDS33 PSDKMKWCLRVNPKGLDDESKDYLSLYLLLVSCPKSEVRAKFKFSLLNAKREETKAMESQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK
::::::::::::::::::::::::::::::::::::::::::::::::::::... : .:
CCDS33 RAYRFVQGKDWGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGHTNTNTLK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEESKKNR
:::::::..::.::::.::::: . : ::::.:::..::::::::.::::::::::::::
CCDS33 VPECRLAEDLGNLWENTRFTDCSFFVRGQEFKAHKSVLAARSPVFNAMFEHEMEESKKNR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 VEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCSNLSVE
:::::..:::::::: :::::.:::::::::.::::::::::::::::::.:::::::::
CCDS33 VEINDLDPEVFKEMMRFIYTGRAPNLDKMADNLLAAADKYALERLKVMCEEALCSNLSVE
250 260 270 280 290 300
310 320 330 340
pF1KB8 NAAEILILADLHSADQLKTQAVDFINY------------------HASDVLETSGWKSMV
:.:. :.:::::::.:::.::.:::: .:.:..::::::::.
CCDS33 NVADTLVLADLHSAEQLKAQAIDFINRCSVLRQLGCKDGKNWNSNQATDIMETSGWKSMI
310 320 330 340 350 360
350 360 370
pF1KB8 VSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
:::::::::.:.::::::: .: ::::::::
CCDS33 QSHPHLVAEAFRALASAQCPQFGIPRKRLKQS
370 380 390
>>CCDS34609.1 KLHL7 gene_id:55975|Hs108|chr7 (586 aa)
initn: 297 init1: 273 opt: 279 Z-score: 339.1 bits: 72.1 E(32554): 1.4e-12
Smith-Waterman score: 279; 32.2% identity (64.9% similar) in 174 aa overlap (183-351:23-196)
160 170 180 190 200
pF1KB8 DKLTLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSR----FTDCCLCVAG
: .: . :. .: : . : : :
CCDS34 MAASGVEKSSKKKTEKKLAAREEAKLLAGFMGVMNNMRKQKTLCDVILMVQE
10 20 30 40 50
210 220 230 240 250 260
pF1KB8 QEFQAHKAILAARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDK
... ::...::: : :. :: .: :::. .::..:.::....... : ::.. ..
CCDS34 RKIPAHRVVLAAASHFFNLMFTTNMLESKSFEVELKDAEPDIIEQLVEFAYTARISVNSN
60 70 80 90 100 110
270 280 290 300 310 320
pF1KB8 MADDLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYH
...:: ::..: .: .: :: : : .... : : .::. . .::. : :::. :
CCDS34 NVQSLLDAANQYQIEPVKKMCVDFLKEQVDASNCLGISVLAECLDCPELKATADDFIHQH
120 130 140 150 160 170
330 340 350 360 370
pF1KB8 ASDVLETSGWKSMVVSH-PHLVAEAYRSLASAQCPFLGPPRKRLKQS
..: .:. . .. :.. ::. .
CCDS34 FTEVYKTDEFLQLDVKRVTHLLNQDTLTVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAK
180 190 200 210 220 230
>>CCDS3245.2 KLHL6 gene_id:89857|Hs108|chr3 (621 aa)
initn: 262 init1: 262 opt: 272 Z-score: 330.1 bits: 70.5 E(32554): 4.6e-12
Smith-Waterman score: 272; 33.5% identity (64.5% similar) in 155 aa overlap (195-349:68-221)
170 180 190 200 210 220
pF1KB8 QDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPV
::. .:: ::: :::. :...::: :
CCDS32 LVEILNGEKVKFDDAGLSLILQNGLETLRMENA-LTDVILCVDIQEFSCHRVVLAAASNY
40 50 60 70 80 90
230 240 250 260 270 280
pF1KB8 FSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALER
: ::: ....:. ..:. :. :. :... .. . ::.:: . .. .: ::. . . :
CCDS32 FRAMFCNDLKEKYEKRIIIKGVDAETMHTLLDYTYTSKALITKQNVQRVLEAANLFQFLR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KB8 LKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVS
. : . : :. :: . :: ::: :: :.:: :. ..: . ..:.. . .. :.
CCDS32 MVDACASFLTEALNPENCVGILRLADTHSLDSLKKQVQSYIIQNFVQILNSEEFLDLPVD
160 170 180 190 200 210
350 360 370
pF1KB8 HPHLVAEAYRSLASAQCPFLGPPRKRLKQS
: .
CCDS32 TLHHILKSDDLYVTEEAQVFETVMSWVRHKPSERLCLLPYVLENVRLPLLDPWYFVETVE
220 230 240 250 260 270
>>CCDS5378.2 KLHL7 gene_id:55975|Hs108|chr7 (538 aa)
initn: 286 init1: 262 opt: 265 Z-score: 322.5 bits: 68.9 E(32554): 1.2e-11
Smith-Waterman score: 265; 33.3% identity (68.7% similar) in 147 aa overlap (206-351:2-148)
180 190 200 210 220 230
pF1KB8 MNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFEHEMEE
: ... ::...::: : :. :: .: :
CCDS53 MVQERKIPAHRVVLAAASHFFNLMFTTNMLE
10 20 30
240 250 260 270 280 290
pF1KB8 SKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKYALERLKVMCEDALCS
::. .::..:.::....... : ::.. .. ...:: ::..: .: .: :: : :
CCDS53 SKSFEVELKDAEPDIIEQLVEFAYTARISVNSNNVQSLLDAANQYQIEPVKKMCVDFLKE
40 50 60 70 80 90
300 310 320 330 340 350
pF1KB8 NLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGWKSMVVSH-PHLVAEAYR
.... : : .::. . .::. : :::. : ..: .:. . .. :.. ::. .
CCDS53 QVDASNCLGISVLAECLDCPELKATADDFIHQHFTEVYKTDEFLQLDVKRVTHLLNQDTL
100 110 120 130 140 150
360 370
pF1KB8 SLASAQCPFLGPPRKRLKQS
CCDS53 TVRAEDQVYDAAVRWLKYDEPNRQPFMVDILAKVRFPLISKNFLSKTVQAEPLIQDNPEC
160 170 180 190 200 210
>>CCDS47418.1 BTBD9 gene_id:114781|Hs108|chr6 (612 aa)
initn: 174 init1: 98 opt: 258 Z-score: 313.0 bits: 67.3 E(32554): 4.1e-11
Smith-Waterman score: 258; 29.4% identity (64.4% similar) in 160 aa overlap (186-341:22-181)
160 170 180 190 200 210
pF1KB8 TLFCEVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAGQEFQAHK
:....:.: . .. : . : ..: ::.
CCDS47 MSNSHPLRPFTAVGEIDHVHILSEHIGALLIGEEYGDVTFVVEKKRFPAHR
10 20 30 40 50
220 230 240 250 260 270
pF1KB8 AILAARSPVFSAMFEHEMEESK-KNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMAD---
.::::: : :.. :.::. . .. ..:. :.: .. .::::.: :. .
CCDS47 VILAARCQYFRALLYGGMRESQPEAEIPLQDTTAEAFTMLLKYIYTGRATLTDEKEEVLL
60 70 80 90 100 110
280 290 300 310 320 330
pF1KB8 DLLAAADKYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASD
:.:. : ::.. .:. . ::. :...:. . .:.:.: .: . :.. .:..
CCDS47 DFLSLAHKYGFPELEDSTSEYLCTILNIQNVCMTFDVASLYSLPKLTCMCCMFMDRNAQE
120 130 140 150 160 170
340 350 360 370
pF1KB8 VLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
:: . :. :.
CCDS47 VLSSEGFLSLSKTALLNIVLRDSFAAPEKDIFLALLNWCKHNSKENHAEIMQAVRLPLMS
180 190 200 210 220 230
>>CCDS30575.1 KLHL21 gene_id:9903|Hs108|chr1 (597 aa)
initn: 232 init1: 232 opt: 254 Z-score: 308.3 bits: 66.4 E(32554): 7.5e-11
Smith-Waterman score: 254; 33.3% identity (61.8% similar) in 144 aa overlap (190-332:25-168)
160 170 180 190 200 210
pF1KB8 EVSVVQDSVNISGQNTMNMVKVPECRLADELGGLWENSRFTDCCLCVAG-QEFQAHKAIL
:. : . .: : : .:: ..: ::.:.:
CCDS30 MERPAPLAVLPFSDPAHALSLLRGLSQLRAERKFLDVTLEAAGGRDFPAHRAVL
10 20 30 40 50
220 230 240 250 260 270
pF1KB8 AARSPVFSAMFEHEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAAD
:: :: : ::: ...::. .::... : :.... .. : :::.. :. :: :::
CCDS30 AAASPYFRAMFAGQLRESRAERVRLHGVPPDMLQLLLDFSYTGRVAVSGDNAEPLLRAAD
60 70 80 90 100 110
280 290 300 310 320 330
pF1KB8 KYALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHASDVLETSGW
. .: : : ..:.. : .. .:. : . : . : :: :....
CCDS30 LLQFPAVKEACGAFLQQQLDLANCLDMQDFAEAFSCSGLASAAQRFILRHVGELGAEQLE
120 130 140 150 160 170
340 350 360 370
pF1KB8 KSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
CCDS30 RLPLARLLRYLRDDGLCVPKEEAAYQLALRWVRADPPRRAAHWPQLLEAVRLPFVRRFYL
180 190 200 210 220 230
374 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:05:33 2016 done: Fri Nov 4 14:05:34 2016
Total Scan time: 2.720 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]