Result of FASTA (omim) for
pFN21AB8632
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8632, 838 aa
1>>>pF1KB8632 838 - 838 aa - 838 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1105+/-0.000467; mu= 12.7463+/- 0.029
mean_var=129.4801+/-26.435, 0's: 0 Z-trim(113.6): 112 B-trim: 469 in 1/50
Lambda= 0.112713
statistics sampled from 22831 (22947) to 22831 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.617), E-opt: 0.2 (0.269), width: 16
Scan time: 11.180
The best scores are: opt bits E(85289)
NP_001171805 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4 0
NP_001004051 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4 0
NP_612446 (OMIM: 300969) G-protein coupled recepto ( 838) 5566 917.4 0
NP_001171804 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4 0
NP_001171803 (OMIM: 300969) G-protein coupled rece ( 838) 5566 917.4 0
NP_001092881 (OMIM: 300417) G-protein coupled rece (1395) 2043 344.7 1.8e-93
XP_016885471 (OMIM: 300417) PREDICTED: G-protein c (1395) 2043 344.7 1.8e-93
NP_001092880 (OMIM: 300417) G-protein coupled rece (1395) 2043 344.7 1.8e-93
XP_016885470 (OMIM: 300417) PREDICTED: G-protein c (1395) 2043 344.7 1.8e-93
NP_055525 (OMIM: 300417) G-protein coupled recepto (1395) 2043 344.7 1.8e-93
NP_001171656 (OMIM: 300417) G-protein coupled rece (1395) 2043 344.7 1.8e-93
NP_001136001 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_085142 (OMIM: 300921) protein BHLHb9 [Homo sapi ( 547) 824 146.2 3.9e-34
NP_001136000 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_001135997 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_001135999 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_001136002 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_001135996 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_001135998 (OMIM: 300921) protein BHLHb9 [Homo s ( 547) 824 146.2 3.9e-34
NP_057692 (OMIM: 300362) armadillo repeat-containi ( 453) 424 81.1 1.3e-14
NP_808817 (OMIM: 300364) armadillo repeat-containi ( 379) 415 79.5 3.1e-14
XP_005262198 (OMIM: 300364) PREDICTED: armadillo r ( 379) 415 79.5 3.1e-14
NP_808816 (OMIM: 300364) armadillo repeat-containi ( 379) 415 79.5 3.1e-14
NP_057691 (OMIM: 300364) armadillo repeat-containi ( 379) 415 79.5 3.1e-14
XP_016868176 (OMIM: 611864) PREDICTED: armadillo r ( 273) 404 77.7 8.1e-14
XP_011514904 (OMIM: 611864) PREDICTED: armadillo r ( 280) 404 77.7 8.3e-14
NP_001154481 (OMIM: 611864) armadillo repeat-conta ( 308) 404 77.7 9e-14
XP_011514903 (OMIM: 611864) PREDICTED: armadillo r ( 316) 404 77.7 9.1e-14
NP_114111 (OMIM: 611864) armadillo repeat-containi ( 343) 404 77.7 9.8e-14
XP_016868173 (OMIM: 611864) PREDICTED: armadillo r ( 352) 404 77.7 1e-13
XP_005278172 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885477 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_005278171 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_005278168 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885481 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
NP_055597 (OMIM: 300363) armadillo repeat-containi ( 632) 321 64.4 1.8e-09
XP_016885479 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885478 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
NP_808818 (OMIM: 300363) armadillo repeat-containi ( 632) 321 64.4 1.8e-09
XP_016885476 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885486 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885484 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_005278173 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885482 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_005278166 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_005278174 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_011529373 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
NP_001269160 (OMIM: 300363) armadillo repeat-conta ( 632) 321 64.4 1.8e-09
XP_005278167 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
XP_016885485 (OMIM: 300363) PREDICTED: armadillo r ( 632) 321 64.4 1.8e-09
>>NP_001171805 (OMIM: 300969) G-protein coupled receptor (838 aa)
initn: 5566 init1: 5566 opt: 5566 Z-score: 4898.5 bits: 917.4 E(85289): 0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
730 740 750 760 770 780
790 800 810 820 830
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
790 800 810 820 830
>>NP_001004051 (OMIM: 300969) G-protein coupled receptor (838 aa)
initn: 5566 init1: 5566 opt: 5566 Z-score: 4898.5 bits: 917.4 E(85289): 0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
730 740 750 760 770 780
790 800 810 820 830
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
790 800 810 820 830
>>NP_612446 (OMIM: 300969) G-protein coupled receptor-as (838 aa)
initn: 5566 init1: 5566 opt: 5566 Z-score: 4898.5 bits: 917.4 E(85289): 0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
730 740 750 760 770 780
790 800 810 820 830
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_612 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
790 800 810 820 830
>>NP_001171804 (OMIM: 300969) G-protein coupled receptor (838 aa)
initn: 5566 init1: 5566 opt: 5566 Z-score: 4898.5 bits: 917.4 E(85289): 0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
730 740 750 760 770 780
790 800 810 820 830
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
790 800 810 820 830
>>NP_001171803 (OMIM: 300969) G-protein coupled receptor (838 aa)
initn: 5566 init1: 5566 opt: 5566 Z-score: 4898.5 bits: 917.4 E(85289): 0
Smith-Waterman score: 5566; 100.0% identity (100.0% similar) in 838 aa overlap (1-838:1-838)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETFPGTQGQKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWTGE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETSVRSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWVGENT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNLFRPRVREEANIRSKLRTNREDCFESESEDEFYKQSWVLPGEEANSRFRHRDKEDPNT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALKLRAQKDVDSDRVKQEPRFEEEVIIGSWFWAEKEASLEGGASAICESEPGTEEGAIGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIPEEASEMLEAKPKNLELSPEGEEQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB8 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESLLQPDQPSPEFTFQYDPSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEE
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB8 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLLLMDKIRDPFIHEISKIAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLE
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB8 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NMIHMAPPYPNLNMIETFICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYM
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB8 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGFLSLLTTANARTKFHVLKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIV
730 740 750 760 770 780
790 800 810 820 830
pF1KB8 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IKMFQNISNIIKSGKMSLIDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
790 800 810 820 830
>>NP_001092881 (OMIM: 300417) G-protein coupled receptor (1395 aa)
initn: 2409 init1: 1468 opt: 2043 Z-score: 1799.2 bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)
10 20 30 40 50 60
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
.: .: : ::: .: ... .. .:
NP_001 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
530 540 550 560 570 580
70 80 90 100 110 120
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
:.. : .: ..: ::. : . : :. ...: . : . ::.. . : :
NP_001 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
590 600 610 620 630 640
130 140 150 160 170
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
:. .. . :: . . :. .:: . : : .:. ::. ....:
NP_001 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
650 660 670 680 690 700
180 190 200 210 220 230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
: . :. . : :. ::.:. :. .. ..::. .: ::. :: :
NP_001 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
710 720 730 740 750 760
240 250 260 270 280
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
. : .:: .. :: .. ..: . .: ..: ...:. : :: :...:.
NP_001 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
770 780 790 800 810 820
290 300 310 320 330
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
. .: ... :...:: : .. ..: :::. :.:. :
NP_001 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
830 840 850 860 870
340 350 360 370 380
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
: : :::. . . :. .. . . .. :. .:..: :. .::.:.
NP_001 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
880 890 900 910 920 930
390 400 410 420 430 440
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
::::.. .: : :. : :::.: .::::: :: . ::. ... :. .. .
NP_001 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
940 950 960 970 980 990
450 460 470 480 490 500
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
:.::: ::::: ::: :. :: ::... : ..: : . : :::.:.::::.::::
NP_001 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
1000 1010 1020 1030 1040 1050
510 520 530 540 550
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
. ::: : ::: .:.::. ::. .::.:. ::::::.:::::::::::::: ::::
NP_001 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
1060 1070 1080 1090 1100 1110
560 570 580 590 600 610
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
NP_001 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
1120 1130 1140 1150 1160 1170
620 630 640 650 660 670
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
NP_001 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
1180 1190 1200 1210 1220 1230
680 690 700 710 720 730
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
NP_001 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
1240 1250 1260 1270 1280 1290
740 750 760 770 780 790
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
:::::::::: ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. . .
NP_001 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
1300 1310 1320 1330 1340 1350
800 810 820 830
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::..:::::::.. :..::.::.. ::::::: :..
NP_001 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
1360 1370 1380 1390
>--
initn: 922 init1: 376 opt: 883 Z-score: 779.8 bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::: .::.::::: ::::..: : ::::::::::::::::
NP_001 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
: : :::::.. .:: :: :.:.. :::::: :. ::::: .
NP_001 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
50 60 70 80
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
: :.::: ::: .::.: .:..: :::: .: ::....: :.:.: :: ::::::.:.
NP_001 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
90 100 110 120 130 140
190 200 210 220 230
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
:.:: .. : :.:: : ::::::::: :: ...::: .: : .:. :..: ::.
NP_001 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
:.:.... : : ....:: : :....: :: ...:: :. : ::::::. . ::.
NP_001 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
..::. :: :. : ::..:...: :: : : : . .:: :.::. : . :
NP_001 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
270 280 290 300 310 320
360 370 380 390 400
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
.. :. . ::... .: : .:.: : ::.. : .::: ..
NP_001 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
330 340 350 360 370 380
410 420 430 440 450
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
: : ..: .:: :. :. .:: ..::.. : :.. . :.:.:.::::: ..
NP_001 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
::
NP_001 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
450 460 470 480 490 500
>>XP_016885471 (OMIM: 300417) PREDICTED: G-protein coupl (1395 aa)
initn: 2409 init1: 1468 opt: 2043 Z-score: 1799.2 bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)
10 20 30 40 50 60
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
.: .: : ::: .: ... .. .:
XP_016 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
530 540 550 560 570 580
70 80 90 100 110 120
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
:.. : .: ..: ::. : . : :. ...: . : . ::.. . : :
XP_016 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
590 600 610 620 630 640
130 140 150 160 170
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
:. .. . :: . . :. .:: . : : .:. ::. ....:
XP_016 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
650 660 670 680 690 700
180 190 200 210 220 230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
: . :. . : :. ::.:. :. .. ..::. .: ::. :: :
XP_016 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
710 720 730 740 750 760
240 250 260 270 280
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
. : .:: .. :: .. ..: . .: ..: ...:. : :: :...:.
XP_016 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
770 780 790 800 810 820
290 300 310 320 330
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
. .: ... :...:: : .. ..: :::. :.:. :
XP_016 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
830 840 850 860 870
340 350 360 370 380
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
: : :::. . . :. .. . . .. :. .:..: :. .::.:.
XP_016 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
880 890 900 910 920 930
390 400 410 420 430 440
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
::::.. .: : :. : :::.: .::::: :: . ::. ... :. .. .
XP_016 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
940 950 960 970 980 990
450 460 470 480 490 500
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
:.::: ::::: ::: :. :: ::... : ..: : . : :::.:.::::.::::
XP_016 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
1000 1010 1020 1030 1040 1050
510 520 530 540 550
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
. ::: : ::: .:.::. ::. .::.:. ::::::.:::::::::::::: ::::
XP_016 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
1060 1070 1080 1090 1100 1110
560 570 580 590 600 610
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
XP_016 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
1120 1130 1140 1150 1160 1170
620 630 640 650 660 670
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
XP_016 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
1180 1190 1200 1210 1220 1230
680 690 700 710 720 730
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
XP_016 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
1240 1250 1260 1270 1280 1290
740 750 760 770 780 790
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
:::::::::: ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. . .
XP_016 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
1300 1310 1320 1330 1340 1350
800 810 820 830
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::..:::::::.. :..::.::.. ::::::: :..
XP_016 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
1360 1370 1380 1390
>--
initn: 922 init1: 376 opt: 883 Z-score: 779.8 bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::: .::.::::: ::::..: : ::::::::::::::::
XP_016 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
: : :::::.. .:: :: :.:.. :::::: :. ::::: .
XP_016 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
50 60 70 80
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
: :.::: ::: .::.: .:..: :::: .: ::....: :.:.: :: ::::::.:.
XP_016 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
90 100 110 120 130 140
190 200 210 220 230
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
:.:: .. : :.:: : ::::::::: :: ...::: .: : .:. :..: ::.
XP_016 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
:.:.... : : ....:: : :....: :: ...:: :. : ::::::. . ::.
XP_016 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
..::. :: :. : ::..:...: :: : : : . .:: :.::. : . :
XP_016 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
270 280 290 300 310 320
360 370 380 390 400
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
.. :. . ::... .: : .:.: : ::.. : .::: ..
XP_016 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
330 340 350 360 370 380
410 420 430 440 450
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
: : ..: .:: :. :. .:: ..::.. : :.. . :.:.:.::::: ..
XP_016 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
::
XP_016 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
450 460 470 480 490 500
>>NP_001092880 (OMIM: 300417) G-protein coupled receptor (1395 aa)
initn: 2409 init1: 1468 opt: 2043 Z-score: 1799.2 bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)
10 20 30 40 50 60
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
.: .: : ::: .: ... .. .:
NP_001 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
530 540 550 560 570 580
70 80 90 100 110 120
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
:.. : .: ..: ::. : . : :. ...: . : . ::.. . : :
NP_001 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
590 600 610 620 630 640
130 140 150 160 170
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
:. .. . :: . . :. .:: . : : .:. ::. ....:
NP_001 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
650 660 670 680 690 700
180 190 200 210 220 230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
: . :. . : :. ::.:. :. .. ..::. .: ::. :: :
NP_001 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
710 720 730 740 750 760
240 250 260 270 280
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
. : .:: .. :: .. ..: . .: ..: ...:. : :: :...:.
NP_001 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
770 780 790 800 810 820
290 300 310 320 330
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
. .: ... :...:: : .. ..: :::. :.:. :
NP_001 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
830 840 850 860 870
340 350 360 370 380
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
: : :::. . . :. .. . . .. :. .:..: :. .::.:.
NP_001 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
880 890 900 910 920 930
390 400 410 420 430 440
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
::::.. .: : :. : :::.: .::::: :: . ::. ... :. .. .
NP_001 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
940 950 960 970 980 990
450 460 470 480 490 500
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
:.::: ::::: ::: :. :: ::... : ..: : . : :::.:.::::.::::
NP_001 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
1000 1010 1020 1030 1040 1050
510 520 530 540 550
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
. ::: : ::: .:.::. ::. .::.:. ::::::.:::::::::::::: ::::
NP_001 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
1060 1070 1080 1090 1100 1110
560 570 580 590 600 610
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
NP_001 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
1120 1130 1140 1150 1160 1170
620 630 640 650 660 670
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
NP_001 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
1180 1190 1200 1210 1220 1230
680 690 700 710 720 730
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
NP_001 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
1240 1250 1260 1270 1280 1290
740 750 760 770 780 790
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
:::::::::: ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. . .
NP_001 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
1300 1310 1320 1330 1340 1350
800 810 820 830
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::..:::::::.. :..::.::.. ::::::: :..
NP_001 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
1360 1370 1380 1390
>--
initn: 922 init1: 376 opt: 883 Z-score: 779.8 bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::: .::.::::: ::::..: : ::::::::::::::::
NP_001 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
: : :::::.. .:: :: :.:.. :::::: :. ::::: .
NP_001 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
50 60 70 80
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
: :.::: ::: .::.: .:..: :::: .: ::....: :.:.: :: ::::::.:.
NP_001 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
90 100 110 120 130 140
190 200 210 220 230
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
:.:: .. : :.:: : ::::::::: :: ...::: .: : .:. :..: ::.
NP_001 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
:.:.... : : ....:: : :....: :: ...:: :. : ::::::. . ::.
NP_001 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
..::. :: :. : ::..:...: :: : : : . .:: :.::. : . :
NP_001 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
270 280 290 300 310 320
360 370 380 390 400
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
.. :. . ::... .: : .:.: : ::.. : .::: ..
NP_001 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
330 340 350 360 370 380
410 420 430 440 450
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
: : ..: .:: :. :. .:: ..::.. : :.. . :.:.:.::::: ..
NP_001 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
::
NP_001 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
450 460 470 480 490 500
>>XP_016885470 (OMIM: 300417) PREDICTED: G-protein coupl (1395 aa)
initn: 2409 init1: 1468 opt: 2043 Z-score: 1799.2 bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)
10 20 30 40 50 60
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
.: .: : ::: .: ... .. .:
XP_016 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
530 540 550 560 570 580
70 80 90 100 110 120
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
:.. : .: ..: ::. : . : :. ...: . : . ::.. . : :
XP_016 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
590 600 610 620 630 640
130 140 150 160 170
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
:. .. . :: . . :. .:: . : : .:. ::. ....:
XP_016 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
650 660 670 680 690 700
180 190 200 210 220 230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
: . :. . : :. ::.:. :. .. ..::. .: ::. :: :
XP_016 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
710 720 730 740 750 760
240 250 260 270 280
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
. : .:: .. :: .. ..: . .: ..: ...:. : :: :...:.
XP_016 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
770 780 790 800 810 820
290 300 310 320 330
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
. .: ... :...:: : .. ..: :::. :.:. :
XP_016 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
830 840 850 860 870
340 350 360 370 380
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
: : :::. . . :. .. . . .. :. .:..: :. .::.:.
XP_016 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
880 890 900 910 920 930
390 400 410 420 430 440
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
::::.. .: : :. : :::.: .::::: :: . ::. ... :. .. .
XP_016 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
940 950 960 970 980 990
450 460 470 480 490 500
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
:.::: ::::: ::: :. :: ::... : ..: : . : :::.:.::::.::::
XP_016 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
1000 1010 1020 1030 1040 1050
510 520 530 540 550
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
. ::: : ::: .:.::. ::. .::.:. ::::::.:::::::::::::: ::::
XP_016 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
1060 1070 1080 1090 1100 1110
560 570 580 590 600 610
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
XP_016 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
1120 1130 1140 1150 1160 1170
620 630 640 650 660 670
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
XP_016 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
1180 1190 1200 1210 1220 1230
680 690 700 710 720 730
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
XP_016 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
1240 1250 1260 1270 1280 1290
740 750 760 770 780 790
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
:::::::::: ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. . .
XP_016 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
1300 1310 1320 1330 1340 1350
800 810 820 830
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::..:::::::.. :..::.::.. ::::::: :..
XP_016 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
1360 1370 1380 1390
>--
initn: 922 init1: 376 opt: 883 Z-score: 779.8 bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::: .::.::::: ::::..: : ::::::::::::::::
XP_016 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
: : :::::.. .:: :: :.:.. :::::: :. ::::: .
XP_016 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
50 60 70 80
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
: :.::: ::: .::.: .:..: :::: .: ::....: :.:.: :: ::::::.:.
XP_016 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
90 100 110 120 130 140
190 200 210 220 230
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
:.:: .. : :.:: : ::::::::: :: ...::: .: : .:. :..: ::.
XP_016 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
:.:.... : : ....:: : :....: :: ...:: :. : ::::::. . ::.
XP_016 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
..::. :: :. : ::..:...: :: : : : . .:: :.::. : . :
XP_016 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
270 280 290 300 310 320
360 370 380 390 400
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
.. :. . ::... .: : .:.: : ::.. : .::: ..
XP_016 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
330 340 350 360 370 380
410 420 430 440 450
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
: : ..: .:: :. :. .:: ..::.. : :.. . :.:.:.::::: ..
XP_016 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
::
XP_016 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
450 460 470 480 490 500
>>NP_055525 (OMIM: 300417) G-protein coupled receptor-as (1395 aa)
initn: 2409 init1: 1468 opt: 2043 Z-score: 1799.2 bits: 344.7 E(85289): 1.8e-93
Smith-Waterman score: 2128; 47.2% identity (69.2% similar) in 850 aa overlap (39-838:559-1395)
10 20 30 40 50 60
pF1KB8 SAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTG--ARPKTETKSVPAARPKTEA
.: .: : ::: .: ... .. .:
NP_055 SVESGVGVSCESRTRSEEEEVIGPWFWSGEQVDIEAGIGEEARPGAEEETIFGSWFWAEN
530 540 550 560 570 580
70 80 90 100 110 120
pF1KB8 QAMSGARPKTEVQVMGGARPKTEAQGITGAR--PKTDARAVGGARSKTDAKAIPGAR-PK
:.. : .: ..: ::. : . : :. ...: . : . ::.. . : :
NP_055 QTYMDCRAETSCDTMQGAE---EEEPIIGSWFWTRVEACVEGDVNSKSSLEDKEEAMIPC
590 600 610 620 630 640
130 140 150 160 170
pF1KB8 DEAQAWAQSEFGTEAVSQ-AEGVSQTNAVA--W----PLATAESGSVTKSKGLSMDRELV
:. .. . :: . . :. .:: . : : .:. ::. ....:
NP_055 FGAKEEVSMKHGTGVRCRFMAGAEETNNKSCFWAEKEPCMYPAGGGSWKSRP-EEEEDIV
650 660 670 680 690 700
180 190 200 210 220 230
pF1KB8 NVDAETFPGTQGQKGIQPWFGPGEETNM-GSWCYSRPRAREEASNESGFWSADE-----T
: . :. . : :. ::.:. :. .. ..::. .: ::. :: :
NP_055 NSWFWSRKYTKPEAIIGSWLWATEESNIDGTGEKAKLLTEEETIINSWFWKEDEAISEAT
710 720 730 740 750 760
240 250 260 270 280
pF1KB8 STASSFWTGEETSV-RSWPREESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEAS
. : .:: .. :: .. ..: . .: ..: ...:. : :: :...:.
NP_055 DREESRPEAEEGDIIGSW--FWAGEEDRLEPAAETREEDRLAAEKEGIVGSWFGAREET-
770 780 790 800 810 820
290 300 310 320 330
pF1KB8 NPFSFWVGENTNNLFRPRVREEANIRSKLRTNREDC--------FESES---EDEFYKQS
. .: ... :...:: : .. ..: :::. :.:. :
NP_055 --IRREAGSCSKS--SPKAEEEEVIIGSWFWEEEASPEAVAGVGFESKPGTEEEEITVGS
830 840 850 860 870
340 350 360 370 380
pF1KB8 WVLPGEEANSRFRHRDKEDPNTALK---LRAQKDVDSDRVKQE--------PRFEEEVII
: : :::. . . :. .. . . .. :. .:..: :. .::.:.
NP_055 WFWPEEEASIQAGSQAVEEMESETEEETIFGSWFWDGKEVSEEAGPCCVSKPEDDEEMIV
880 890 900 910 920 930
390 400 410 420 430 440
pF1KB8 GSWFWAEKEASLEGGASAICESEPGTEEGAIGGSAYWAEE----KSSLGAVAREEAKPES
::::.. .: : :. : :::.: .::::: :: . ::. ... :. .. .
NP_055 ESWFWSRDKAIKETGTVATCESKPENEEGAIVGSWFEAEDEVDNRTDNGSNCGSRTLAD-
940 950 960 970 980 990
450 460 470 480 490 500
pF1KB8 EEEAIFGSWFWDRDEACFDLNPCPVYKVSDRFRDAAE-ELNASSRPQTWDEVTVEFKPGL
:.::: ::::: ::: :. :: ::... : ..: : . : :::.:.::::.::::
NP_055 EDEAIVGSWFWAGDEAHFESNPSPVFRAICRSTCSVEQEPDPSRRPQSWEEVTVQFKPGP
1000 1010 1020 1030 1040 1050
510 520 530 540 550
pF1KB8 FHGVGFRSTSPFGIPEEAS----EMLEAKPKNLELSPEGEEQESLLQPDQPSPEFTFQYD
. ::: : ::: .:.::. ::. .::.:. ::::::.:::::::::::::: ::::
NP_055 WGRVGFPSISPFRFPKEAASLFCEMFGGKPRNMVLSPEGEDQESLLQPDQPSPEFPFQYD
1060 1070 1080 1090 1100 1110
560 570 580 590 600 610
pF1KB8 PSYRSVREIREHLRARESAESESWSCSCIQCELKIGSEEFEEFLLLMDKIRDPFIHEISK
::::::.::::::::.::.: :: ::.:::::::::::::::.::::.::::::::::::
NP_055 PSYRSVQEIREHLRAKESTEPESSSCNCIQCELKIGSEEFEELLLLMEKIRDPFIHEISK
1120 1130 1140 1150 1160 1170
620 630 640 650 660 670
pF1KB8 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIHMAPPYPNLNMIETF
:::::::::::::::::::::::::::::::::::::::::::::.:::::::::.:.:.
NP_055 IAMGMRSASQFTRDFIRDSGVVSLIETLLNYPSSRVRTSFLENMIRMAPPYPNLNIIQTY
1180 1190 1200 1210 1220 1230
680 690 700 710 720 730
pF1KB8 ICQVCEETLAHSVDSLEQLTGIRMLRHLTMTIDYHTLIANYMSGFLSLLTTANARTKFHV
::.:::::::.:::: :::.::::.:::: : :::::.:::::::::::.:.::.:.:::
NP_055 ICKVCEETLAYSVDSPEQLSGIRMIRHLTTTTDYHTLVANYMSGFLSLLATGNAKTRFHV
1240 1250 1260 1270 1280 1290
740 750 760 770 780 790
pF1KB8 LKMLLNLSENPAVAKKLFSAKALSIFVGLFNIEETNDNIQIVIKMFQNISNIIKSGKMSL
:::::::::: ..:.:.::.:.: :.:::: ::::::::::. .:.::.: ::. . .
NP_055 LKMLLNLSENLFMTKELLSAEAVSEFIGLFNREETNDNIQIVLAIFENIGNNIKK-ETVF
1300 1310 1320 1330 1340 1350
800 810 820 830
pF1KB8 IDDDFSLEPLISAFREFEELAKQLQAQIDNQNDPEVGQQS
::::..:::::::.. :..::.::.. ::::::: :..
NP_055 SDDDFNIEPLISAFHKVEKFAKELQGKTDNQNDPEGDQEN
1360 1370 1380 1390
>--
initn: 922 init1: 376 opt: 883 Z-score: 779.8 bits: 156.0 E(85289): 1.1e-36
Smith-Waterman score: 1039; 42.5% identity (64.7% similar) in 482 aa overlap (1-459:1-445)
10 20 30 40 50 60
pF1KB8 MTGAEIEPSAQAKPEKKAGEEVIAGPERENDVPLVVRPKVRTQATTGARPKTETKSVPAA
::::::: .::.::::: ::::..: : ::::::::::::::::
NP_055 MTGAEIESGAQVKPEKKPGEEVVGGAEIENDVPLVVRPKVRTQA----------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 RPKTEAQAMSGARPKTEVQVMGGARPKTEAQGITGARPKTDARAVGGARSKTDAKAIPGA
: : :::::.. .:: :: :.:.. :::::: :. ::::: .
NP_055 ------QIMPGARPKNKSKVMPGASTKVETS------------AVGGARPKSKAKAIPVS
50 60 70 80
130 140 150 160 170 180
pF1KB8 RPKDEAQAWAQSEFGTEAVSQAEGVSQTNAVAWPLATAESGSVTKSKGLSMDRELVNVDA
: :.::: ::: .::.: .:..: :::: .: ::....: :.:.: :: ::::::.:.
NP_055 RFKEEAQMWAQPRFGAERLSKTERNSQTNIIASPLVSTDSVLVAKTKYLSEDRELVNTDT
90 100 110 120 130 140
190 200 210 220 230
pF1KB8 ETFPGTQG--QKGIQPWFGPGEETNMGSWCYSRPRAREEASNESGFWSADETSTASSFWT
:.:: .. : :.:: : ::::::::: :: ...::: .: : .:. :..: ::.
NP_055 ESFPRRKAHYQAGFQPSFRSKEETNMGSWCCPRPTSKQEASPNSDFKWVDK-SVSSLFWS
150 160 170 180 190 200
240 250 260 270 280 290
pF1KB8 GEETSVRSWP--REESNTRSRHRAKHQTNPRSRPRSKQEAYVDSWSGSEDEASNPFSFWV
:.:.... : : ....:: : :....: :: ...:: :. : ::::::. . ::.
NP_055 GDEVTAKFHPGNRVKDSNRSMHMANQEANTMSRSQTNQELYIASSSGSEDESVKTPWFWA
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB8 GENTNNLFRPRVREEANIRSKLRTNREDCFESES--EDEFYKQSWVLPGEEANSRFRHRD
..::. :: :. : ::..:...: :: : : : . .:: :.::. : . :
NP_055 RDKTNTWSGPR--EDPNSRSRFRSKKEVYVESSSGSEHEDHLESWFGAGKEAKFRSKMRA
270 280 290 300 310 320
360 370 380 390 400
pF1KB8 KEDPNTALKLRAQKD--VDS-----DRVKQEPRF--EEEVIIGSWFWAEKEASLEG----
.. :. . ::... .: : .:.: : ::.. : .::: ..
NP_055 GKEANNRARHRAKREACIDFMPGSIDVIKKESCFWPEENANTFSRPMIKKEARARAMTKE
330 340 350 360 370 380
410 420 430 440 450
pF1KB8 ----GASAICESEPGTEEGAIGGSAYWAEEKSSLGAVAREEAKPESEEEAIFGSWFWDRD
: : ..: .:: :. :. .:: ..::.. : :.. . :.:.:.::::: ..
NP_055 EAKTKARARAKQEARSEEEALIGTWFWATDESSMADEASIESSLQVEDESIIGSWFWTEE
390 400 410 420 430 440
460 470 480 490 500 510
pF1KB8 EACFDLNPCPVYKVSDRFRDAAEELNASSRPQTWDEVTVEFKPGLFHGVGFRSTSPFGIP
::
NP_055 EASMGTGASSKSRPRTDGERIGDSLFGAREKTSMKTGAEATSESILAADDEQVIIGSWFW
450 460 470 480 490 500
838 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 14:00:25 2016 done: Fri Nov 4 14:00:27 2016
Total Scan time: 11.180 Total Display time: 0.330
Function used was FASTA [36.3.4 Apr, 2011]