Result of FASTA (omim) for
pFN21AB8599
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8599, 244 aa
1>>>pF1KB8599 244 - 244 aa - 244 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.2224+/-0.000443; mu= 9.5563+/- 0.027
mean_var=147.6411+/-33.222, 0's: 0 Z-trim(114.3): 220 B-trim: 1378 in 2/51
Lambda= 0.105553
statistics sampled from 23675 (24030) to 23675 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.662), E-opt: 0.2 (0.282), width: 16
Scan time: 5.830
The best scores are: opt bits E(85289)
XP_016879922 (OMIM: 610091) PREDICTED: WD repeat a ( 383) 1626 259.7 5.3e-69
NP_056441 (OMIM: 610091) WD repeat and SOCS box-co ( 421) 1626 259.7 5.7e-69
NP_599027 (OMIM: 610091) WD repeat and SOCS box-co ( 275) 515 90.3 3.6e-18
NP_001290177 (OMIM: 609540) WD repeat-containing p ( 212) 244 48.9 8.1e-06
NP_001290176 (OMIM: 609540) WD repeat-containing p ( 305) 244 49.1 1e-05
XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-c ( 305) 244 49.1 1e-05
NP_079510 (OMIM: 609540) WD repeat-containing prot ( 305) 244 49.1 1e-05
XP_016878126 (OMIM: 609540) PREDICTED: WD repeat-c ( 270) 233 47.4 3e-05
XP_016879923 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 230 46.8 3.6e-05
XP_005258020 (OMIM: 610091) PREDICTED: WD repeat a ( 216) 230 46.8 3.6e-05
XP_016880191 (OMIM: 601545,607432) PREDICTED: plat ( 345) 215 44.8 0.00024
XP_016880188 (OMIM: 601545,607432) PREDICTED: plat ( 410) 215 44.9 0.00027
NP_000421 (OMIM: 601545,607432) platelet-activatin ( 410) 215 44.9 0.00027
XP_016880190 (OMIM: 601545,607432) PREDICTED: plat ( 410) 215 44.9 0.00027
XP_016880189 (OMIM: 601545,607432) PREDICTED: plat ( 410) 215 44.9 0.00027
XP_011522203 (OMIM: 601545,607432) PREDICTED: plat ( 428) 215 44.9 0.00028
XP_011522204 (OMIM: 601545,607432) PREDICTED: plat ( 428) 215 44.9 0.00028
XP_011522205 (OMIM: 601545,607432) PREDICTED: plat ( 428) 215 44.9 0.00028
NP_001186706 (OMIM: 614784,615973) POC1 centriolar ( 436) 206 43.5 0.00072
NP_758440 (OMIM: 614784,615973) POC1 centriolar pr ( 478) 206 43.6 0.00077
NP_438172 (OMIM: 609012) WD repeat-containing prot ( 334) 195 41.7 0.0019
XP_005272220 (OMIM: 609012) PREDICTED: WD repeat-c ( 334) 195 41.7 0.0019
NP_060058 (OMIM: 609012) WD repeat-containing prot ( 334) 195 41.7 0.0019
NP_006444 (OMIM: 605915) transducin beta-like prot ( 808) 196 42.3 0.0031
XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 186 40.3 0.0045
NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 186 40.3 0.0049
NP_001188402 (OMIM: 611668) coronin-7 isoform 3 [H ( 840) 189 41.3 0.0067
NP_001151 (OMIM: 602233) apoptotic protease-activa (1194) 191 41.7 0.0068
NP_863658 (OMIM: 602233) apoptotic protease-activa (1205) 191 41.7 0.0069
NP_620640 (OMIM: 601787) transcription initiation ( 745) 188 41.0 0.0069
NP_037361 (OMIM: 602233) apoptotic protease-activa (1237) 191 41.7 0.007
NP_863651 (OMIM: 602233) apoptotic protease-activa (1248) 191 41.8 0.007
NP_001188401 (OMIM: 611668) coronin-7 isoform 2 [H ( 907) 189 41.3 0.007
NP_078811 (OMIM: 611668) coronin-7 isoform 1 [Homo ( 925) 189 41.3 0.0071
NP_008882 (OMIM: 601787) transcription initiation ( 800) 188 41.1 0.0072
>>XP_016879922 (OMIM: 610091) PREDICTED: WD repeat and S (383 aa)
initn: 1626 init1: 1626 opt: 1626 Z-score: 1359.7 bits: 259.7 E(85289): 5.3e-69
Smith-Waterman score: 1626; 98.7% identity (99.6% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KB8 MASFPPRVNEKEIVRLRTIGELLAPAAPFDKKCGRENWTVAFAPDGSYFAWSQGHRTVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MASFPPRVNEKEIVRLRTIGELLAPAAPFDKKCGRENWTVAFAPDGSYFAWSQGHRTVKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHIIDCGDIVWSLAFGSSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHIIDCGDIVWSLAFGSSVP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLNLVDHTGVVRDLTFAP
::::::::::::::::::::::::::::.::::::::::::::::::::: :::::::::
XP_016 EKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 DGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVVA
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
XP_016 DGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFL
190 200 210 220 230 240
pF1KB8 AILV
XP_016 WNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGMVRFW
250 260 270 280 290 300
>>NP_056441 (OMIM: 610091) WD repeat and SOCS box-contai (421 aa)
initn: 1626 init1: 1626 opt: 1626 Z-score: 1359.3 bits: 259.7 E(85289): 5.7e-69
Smith-Waterman score: 1626; 98.7% identity (99.6% similar) in 238 aa overlap (1-238:1-238)
10 20 30 40 50 60
pF1KB8 MASFPPRVNEKEIVRLRTIGELLAPAAPFDKKCGRENWTVAFAPDGSYFAWSQGHRTVKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MASFPPRVNEKEIVRLRTIGELLAPAAPFDKKCGRENWTVAFAPDGSYFAWSQGHRTVKL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 VPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHIIDCGDIVWSLAFGSSVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHIIDCGDIVWSLAFGSSVP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 EKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLNLVDHTGVVRDLTFAP
::::::::::::::::::::::::::::.::::::::::::::::::::: :::::::::
NP_056 EKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 DGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVVA
::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::
NP_056 DGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFL
190 200 210 220 230 240
pF1KB8 AILV
NP_056 WNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPP
250 260 270 280 290 300
>>NP_599027 (OMIM: 610091) WD repeat and SOCS box-contai (275 aa)
initn: 515 init1: 515 opt: 515 Z-score: 447.1 bits: 90.3 E(85289): 3.6e-18
Smith-Waterman score: 515; 97.5% identity (98.7% similar) in 79 aa overlap (160-238:14-92)
130 140 150 160 170 180
pF1KB8 EWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLNLVDHTGVVRDLTFAPDGSLILVSA
::::::::::: ::::::::::::::::::
NP_599 MASFPPRVNEKEIGKLLLNLVDHTEVVRDLTFAPDGSLILVSA
10 20 30 40
190 200 210 220 230 240
pF1KB8 SRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVVAAILV
:::::::::::.:::::::::::::::::::::::::::::::::::::
NP_599 SRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMI
50 60 70 80 90 100
NP_599 RKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGA
110 120 130 140 150 160
>>NP_001290177 (OMIM: 609540) WD repeat-containing prote (212 aa)
initn: 404 init1: 129 opt: 244 Z-score: 225.4 bits: 48.9 E(85289): 8.1e-06
Smith-Waterman score: 244; 39.8% identity (70.9% similar) in 103 aa overlap (136-238:63-163)
110 120 130 140 150 160
pF1KB8 CGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLN
.. : ::.: .: :.:.:. ::::: .
NP_001 HVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 LVDHTGVVRDLTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPD
: :. .:.:::.:: : .::.:: : ....:.. .:. .: :: .:: . :: ::
NP_001 LEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDVQH-ANLAGTLSGHASWVLNVAFCPD
100 110 120 130 140 150
230 240
pF1KB8 SSMLCSVGASKAVVAAILV
.. . : ...:.:
NP_001 DTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDC
160 170 180 190 200 210
>>NP_001290176 (OMIM: 609540) WD repeat-containing prote (305 aa)
initn: 404 init1: 129 opt: 244 Z-score: 223.5 bits: 49.1 E(85289): 1e-05
Smith-Waterman score: 244; 39.8% identity (70.9% similar) in 103 aa overlap (136-238:156-256)
110 120 130 140 150 160
pF1KB8 CGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLN
.. : ::.: .: :.:.:. ::::: .
NP_001 HVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 LVDHTGVVRDLTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPD
: :. .:.:::.:: : .::.:: : ....:.. .:. .: :: .:: . :: ::
NP_001 LEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDVQH-ANLAGTLSGHASWVLNVAFCPD
190 200 210 220 230 240
230 240
pF1KB8 SSMLCSVGASKAVVAAILV
.. . : ...:.:
NP_001 DTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDC
250 260 270 280 290 300
>>XP_011520396 (OMIM: 609540) PREDICTED: WD repeat-conta (305 aa)
initn: 404 init1: 129 opt: 244 Z-score: 223.5 bits: 49.1 E(85289): 1e-05
Smith-Waterman score: 244; 39.8% identity (70.9% similar) in 103 aa overlap (136-238:156-256)
110 120 130 140 150 160
pF1KB8 CGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLN
.. : ::.: .: :.:.:. ::::: .
XP_011 HVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 LVDHTGVVRDLTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPD
: :. .:.:::.:: : .::.:: : ....:.. .:. .: :: .:: . :: ::
XP_011 LEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDVQH-ANLAGTLSGHASWVLNVAFCPD
190 200 210 220 230 240
230 240
pF1KB8 SSMLCSVGASKAVVAAILV
.. . : ...:.:
XP_011 DTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDC
250 260 270 280 290 300
>>NP_079510 (OMIM: 609540) WD repeat-containing protein (305 aa)
initn: 404 init1: 129 opt: 244 Z-score: 223.5 bits: 49.1 E(85289): 1e-05
Smith-Waterman score: 244; 39.8% identity (70.9% similar) in 103 aa overlap (136-238:156-256)
110 120 130 140 150 160
pF1KB8 CGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLN
.. : ::.: .: :.:.:. ::::: .
NP_079 HVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 LVDHTGVVRDLTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPD
: :. .:.:::.:: : .::.:: : ....:.. .:. .: :: .:: . :: ::
NP_079 LEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDVQH-ANLAGTLSGHASWVLNVAFCPD
190 200 210 220 230 240
230 240
pF1KB8 SSMLCSVGASKAVVAAILV
.. . : ...:.:
NP_079 DTHFVSSSSDKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYDC
250 260 270 280 290 300
>>XP_016878126 (OMIM: 609540) PREDICTED: WD repeat-conta (270 aa)
initn: 386 init1: 129 opt: 233 Z-score: 215.1 bits: 47.4 E(85289): 3e-05
Smith-Waterman score: 233; 40.6% identity (69.8% similar) in 96 aa overlap (136-231:156-249)
110 120 130 140 150 160
pF1KB8 CGDIVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNSGRIKIWDVYTGKLLLN
.. : ::.: .: :.:.:. ::::: .
XP_016 HVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHT
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB8 LVDHTGVVRDLTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPD
: :. .:.:::.:: : .::.:: : ....:.. .:. .: :: .:: . :: ::
XP_016 LEGHAMPIRSLTFSPD-SQLLVTASDDGYIKIYDVQH-ANLAGTLSGHASWVLNVAFCPD
190 200 210 220 230 240
230 240
pF1KB8 SSMLCSVGASKAVVAAILV
.. . :
XP_016 DTHFVSRSQCWSGLGWPRQLESRRWTT
250 260 270
>>XP_016879923 (OMIM: 610091) PREDICTED: WD repeat and S (216 aa)
initn: 230 init1: 230 opt: 230 Z-score: 213.8 bits: 46.8 E(85289): 3.6e-05
Smith-Waterman score: 230; 100.0% identity (100.0% similar) in 33 aa overlap (206-238:1-33)
180 190 200 210 220 230
pF1KB8 LTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGAS
::::::::::::::::::::::::::::::
XP_016 MMKVLRGHQNWVYSCAFSPDSSMLCSVGAS
10 20 30
240
pF1KB8 KAVVAAILV
:::
XP_016 KAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFG
40 50 60 70 80 90
>>XP_005258020 (OMIM: 610091) PREDICTED: WD repeat and S (216 aa)
initn: 230 init1: 230 opt: 230 Z-score: 213.8 bits: 46.8 E(85289): 3.6e-05
Smith-Waterman score: 230; 100.0% identity (100.0% similar) in 33 aa overlap (206-238:1-33)
180 190 200 210 220 230
pF1KB8 LTFAPDGSLILVSASRDKTLRVWDLRDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGAS
::::::::::::::::::::::::::::::
XP_005 MMKVLRGHQNWVYSCAFSPDSSMLCSVGAS
10 20 30
240
pF1KB8 KAVVAAILV
:::
XP_005 KAVFLWNMDKYTMIRKLEGHHHDVVACDFSPDGALLATASYDTRVYIWDPHNGDILMEFG
40 50 60 70 80 90
244 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:39:05 2016 done: Fri Nov 4 13:39:06 2016
Total Scan time: 5.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]