Result of FASTA (omim) for
pFN21AB8451
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8451, 364 aa
1>>>pF1KB8451 364 - 364 aa - 364 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.9947+/-0.000499; mu= -5.7868+/- 0.030
mean_var=573.7319+/-127.776, 0's: 0 Z-trim(119.4): 1396 B-trim: 33 in 1/56
Lambda= 0.053545
statistics sampled from 31242 (33387) to 31242 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.391), width: 16
Scan time: 9.260
The best scores are: opt bits E(85289)
NP_002742 (OMIM: 602898) mitogen-activated protein ( 364) 2425 202.4 1.3e-51
NP_620581 (OMIM: 600289) mitogen-activated protein ( 360) 1857 158.5 2.1e-38
NP_001306 (OMIM: 600289) mitogen-activated protein ( 360) 1821 155.8 1.4e-37
XP_011529008 (OMIM: 602898) PREDICTED: mitogen-act ( 256) 1720 147.7 2.7e-35
XP_011512612 (OMIM: 600289) PREDICTED: mitogen-act ( 401) 1651 142.7 1.4e-33
NP_002960 (OMIM: 602399) mitogen-activated protein ( 367) 1592 138.1 3.1e-32
NP_620582 (OMIM: 600289) mitogen-activated protein ( 297) 1509 131.5 2.3e-30
XP_016865790 (OMIM: 600289) PREDICTED: mitogen-act ( 301) 1509 131.5 2.4e-30
XP_016865788 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 1509 131.6 2.5e-30
NP_002745 (OMIM: 602899) mitogen-activated protein ( 365) 1485 129.8 9.5e-30
XP_016865789 (OMIM: 600289) PREDICTED: mitogen-act ( 328) 1473 128.8 1.7e-29
XP_006715061 (OMIM: 600289) PREDICTED: mitogen-act ( 283) 1458 127.6 3.5e-29
XP_016865793 (OMIM: 600289) PREDICTED: mitogen-act ( 258) 1405 123.4 5.7e-28
NP_620583 (OMIM: 600289) mitogen-activated protein ( 307) 1406 123.6 5.9e-28
XP_016865792 (OMIM: 600289) PREDICTED: mitogen-act ( 270) 1305 115.7 1.2e-25
XP_016865791 (OMIM: 600289) PREDICTED: mitogen-act ( 273) 1305 115.7 1.2e-25
NP_002737 (OMIM: 601795) mitogen-activated protein ( 379) 1065 97.4 5.7e-20
NP_620602 (OMIM: 602521) mitogen-activated protein ( 816) 1062 97.7 1e-19
NP_002740 (OMIM: 602521) mitogen-activated protein ( 816) 1062 97.7 1e-19
NP_620603 (OMIM: 602521) mitogen-activated protein ( 816) 1062 97.7 1e-19
NP_620407 (OMIM: 176948) mitogen-activated protein ( 360) 1051 96.3 1.2e-19
NP_002736 (OMIM: 176948) mitogen-activated protein ( 360) 1051 96.3 1.2e-19
NP_001035145 (OMIM: 601795) mitogen-activated prot ( 357) 998 92.2 2e-18
NP_001290181 (OMIM: 602399) mitogen-activated prot ( 357) 955 88.9 2e-17
NP_001310254 (OMIM: 601158) mitogen-activated prot ( 384) 954 88.8 2.2e-17
NP_620634 (OMIM: 601158) mitogen-activated protein ( 384) 954 88.8 2.2e-17
NP_001310250 (OMIM: 601158) mitogen-activated prot ( 384) 954 88.8 2.2e-17
NP_001310251 (OMIM: 601158) mitogen-activated prot ( 427) 954 88.9 2.3e-17
NP_001310259 (OMIM: 601158) mitogen-activated prot ( 427) 954 88.9 2.3e-17
NP_001310252 (OMIM: 601158) mitogen-activated prot ( 427) 954 88.9 2.3e-17
NP_001265476 (OMIM: 601158) mitogen-activated prot ( 427) 954 88.9 2.3e-17
NP_001310253 (OMIM: 601158) mitogen-activated prot ( 384) 945 88.1 3.5e-17
NP_001310256 (OMIM: 601158) mitogen-activated prot ( 384) 945 88.1 3.5e-17
NP_001310231 (OMIM: 601158) mitogen-activated prot ( 384) 945 88.1 3.5e-17
NP_001310255 (OMIM: 601158) mitogen-activated prot ( 384) 945 88.1 3.5e-17
NP_620637 (OMIM: 601158) mitogen-activated protein ( 427) 945 88.2 3.7e-17
NP_001310257 (OMIM: 601158) mitogen-activated prot ( 427) 945 88.2 3.7e-17
NP_001310260 (OMIM: 601158) mitogen-activated prot ( 427) 945 88.2 3.7e-17
NP_001310258 (OMIM: 601158) mitogen-activated prot ( 427) 945 88.2 3.7e-17
XP_016863927 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_016863926 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_016863923 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_016863928 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_016863929 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_016863924 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_016863925 (OMIM: 602897) PREDICTED: mitogen-act ( 384) 935 87.4 6e-17
XP_006714332 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 935 87.4 6.3e-17
XP_005263192 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 935 87.4 6.3e-17
XP_016863919 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 935 87.4 6.3e-17
XP_016863921 (OMIM: 602897) PREDICTED: mitogen-act ( 422) 935 87.4 6.3e-17
>>NP_002742 (OMIM: 602898) mitogen-activated protein kin (364 aa)
initn: 2425 init1: 2425 opt: 2425 Z-score: 1047.5 bits: 202.4 E(85289): 1.3e-51
Smith-Waterman score: 2425; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364)
10 20 30 40 50 60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
310 320 330 340 350 360
pF1KB8 EIEQ
::::
NP_002 EIEQ
>>NP_620581 (OMIM: 600289) mitogen-activated protein kin (360 aa)
initn: 1857 init1: 1857 opt: 1857 Z-score: 810.4 bits: 158.5 E(85289): 2.1e-38
Smith-Waterman score: 1857; 75.5% identity (91.7% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
:: : :::::::::.::::.: :.: :::::::::::.:.:.. .:::::::::::
NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
:.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
NP_620 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
:.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
NP_620 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
NP_620 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
::. :.: ::::: ::.::::: ::. .....: ::::::.::: .:::::::.:..::
NP_620 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
.:::::::.:::::.::: :.:::.: :... ..::: :::.::.:: ::
NP_620 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
310 320 330 340 350 360
pF1KB8 EIEQ
>>NP_001306 (OMIM: 600289) mitogen-activated protein kin (360 aa)
initn: 1821 init1: 1821 opt: 1821 Z-score: 795.4 bits: 155.8 E(85289): 1.4e-37
Smith-Waterman score: 1821; 73.2% identity (91.5% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
:: : :::::::::.::::.: :.: :::::::::::.:.:.. .:::::::::::
NP_001 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
:.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
NP_001 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
:.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
NP_001 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
::::::::::::::::::::::::::::::::::::: :..::::.:.:.::..::...:
NP_001 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHINQLQQIMRLTG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
:: .. .. :..::.::::: ::. .....: ::::::.::: .:::::::.:..::
NP_001 TPPAYLINRMPSHEARNYIQSLTQMPKMNFANVFIGANPLAVDLLEKMLVLDSDKRITAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
.:::::::.:::::.::: :.:::.: :... ..::: :::.::.:: ::
NP_001 QALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDEVISFVPPPLDQEEMES
310 320 330 340 350 360
pF1KB8 EIEQ
>>XP_011529008 (OMIM: 602898) PREDICTED: mitogen-activat (256 aa)
initn: 1720 init1: 1720 opt: 1720 Z-score: 754.7 bits: 147.7 E(85289): 2.7e-35
Smith-Waterman score: 1720; 100.0% identity (100.0% similar) in 256 aa overlap (109-364:1-256)
80 90 100 110 120 130
pF1KB8 KHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGL
::::::::::::::::::::::::::::::
XP_011 MGADLNNIVKCQALSDEHVQFLVYQLLRGL
10 20 30
140 150 160 170 180 190
pF1KB8 KYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMTGYVATRWYRAPEIMLNWM
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 HYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTY
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB8 IQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEP
160 170 180 190 200 210
320 330 340 350 360
pF1KB8 EAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSLEIEQ
220 230 240 250
>>XP_011512612 (OMIM: 600289) PREDICTED: mitogen-activat (401 aa)
initn: 1631 init1: 1631 opt: 1651 Z-score: 724.0 bits: 142.7 E(85289): 1.4e-33
Smith-Waterman score: 1652; 71.8% identity (88.7% similar) in 337 aa overlap (24-351:56-392)
10 20 30 40
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRP-VGSGAYGSVCS--------AYDA
:: : . .: ..::: :.:.
XP_011 PAPLLSVASSGRNFPRGRALLPLRALPVLHLQHPSPCTHAGMRSTVCSTQVRCESAAFDT
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB8 RLRQKVAVKKLSRPFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYL
. .::::::::::::.:::.:::::::::::.::::::::::::::: :.:.:..:::
XP_011 KTGLRVAVKKLSRPFQSIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYL
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB8 VTTLMGADLNNIVKCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCEL
:: ::::::::::::: :.:.:::::.::.:::::::::: ::::::::::.::::::::
XP_011 VTHLMGADLNNIVKCQKLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCEL
150 160 170 180 190 200
170 180 190 200 210 220
pF1KB8 RILDFGLARQADEEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFP
.::::::::..:.:::::::::::::::::::::::::::::::::::::::: :..:::
XP_011 KILDFGLARHTDDEMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFP
210 220 230 240 250 260
230 240 250 260 270 280
pF1KB8 GSDYIDQLKRIMEVVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDL
:.:.::::: :...::::. :.: ::::: ::.::::: ::. .....: ::::::.::
XP_011 GTDHIDQLKLILRLVGTPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLAVDL
270 280 290 300 310 320
290 300 310 320 330 340
pF1KB8 LGRMLVLDSDQRVSAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQE
: .:::::::.:..::.:::::::.:::::.::: :.:::.: :... ..::: :::.:
XP_011 LEKMLVLDSDKRITAAQALAHAYFAQYHDPDDEPVADPYDQSFESRDLLIDEWKSLTYDE
330 340 350 360 370 380
350 360
pF1KB8 VLSFKPPEPPKPPGSLEIEQ
:.:: ::
XP_011 VISFVPPPLDQEEMES
390 400
>>NP_002960 (OMIM: 602399) mitogen-activated protein kin (367 aa)
initn: 1586 init1: 1586 opt: 1592 Z-score: 699.7 bits: 138.1 E(85289): 3.1e-32
Smith-Waterman score: 1592; 63.6% identity (88.4% similar) in 354 aa overlap (1-351:1-354)
10 20 30 40 50
pF1KB8 MSGP---RAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSR
::.: :.::::::..::.::: . :.::::::::.:::: :.: :::.::: :
NP_002 MSSPPPARSGFYRQEVTKTAWEVRAVYRDLQPVGSGAYGAVCSAVDGRTGAKVAIKKLYR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 PFQSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIV
:::: . :.:.:::::::::..::::::::::::: ...::.. ::: .::.::....
NP_002 PFQSELFAKRAYRELRLLKHMRHENVIGLLDVFTPDETLDDFTDFYLVMPFMGTDLGKLM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 KCQALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADE
: . :.....::::::.:.::.:::.::::::::::.:.::::::::.:::::::::::
NP_002 KHEKLGEDRIQFLVYQMLKGLRYIHAAGIIHRDLKPGNLAVNEDCELKILDFGLARQADS
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 EMTGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIME
::::::.::::::::..::::.:.::::::::::::::.. ::.:: :::..::::.::.
NP_002 EMTGYVVTRWYRAPEVILNWMRYTQTVDIWSVGCIMAEMITGKTLFKGSDHLDQLKEIMK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 VVGTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRV
:.::: : . ...:..:..:...:: . .::..::. .:.:::..:: .:::::..:::
NP_002 VTGTPPAEFVQRLQSDEAKNYMKGLPELEKKDFASILTNASPLAVNLLEKMLVLDAEQRV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 SAAEALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPP
.:.::::: :: . :: ::::... ::.: . .:::.:::..::.::::::::
NP_002 TAGEALAHPYFESLHDTEDEPQVQKYDDSFDDVDRTLDEWKRVTYKEVLSFKPPRQLGAR
310 320 330 340 350 360
360
pF1KB8 GSLEIEQ
NP_002 VSKETPL
>>NP_620582 (OMIM: 600289) mitogen-activated protein kin (297 aa)
initn: 1509 init1: 1509 opt: 1509 Z-score: 666.0 bits: 131.5 E(85289): 2.3e-30
Smith-Waterman score: 1509; 77.9% identity (92.1% similar) in 280 aa overlap (1-280:1-280)
10 20 30 40 50 60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
:: : :::::::::.::::.: :.: :::::::::::.:.:.. .:::::::::::
NP_620 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
:.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
NP_620 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
:.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
NP_620 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
NP_620 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
::. :.: ::::: ::.::::: ::. .....: :::::
NP_620 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGKLTIYPHLMDIELVMI
250 260 270 280 290
310 320 330 340 350 360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
>>XP_016865790 (OMIM: 600289) PREDICTED: mitogen-activat (301 aa)
initn: 1509 init1: 1509 opt: 1509 Z-score: 665.9 bits: 131.5 E(85289): 2.4e-30
Smith-Waterman score: 1509; 77.9% identity (92.1% similar) in 280 aa overlap (1-280:1-280)
10 20 30 40 50 60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
:: : :::::::::.::::.: :.: :::::::::::.:.:.. .:::::::::::
XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
:.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
:.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
::. :.: ::::: ::.::::: ::. .....: :::::
XP_016 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
XP_016 K
>>XP_016865788 (OMIM: 600289) PREDICTED: mitogen-activat (328 aa)
initn: 1509 init1: 1509 opt: 1509 Z-score: 665.5 bits: 131.6 E(85289): 2.5e-30
Smith-Waterman score: 1509; 77.9% identity (92.1% similar) in 280 aa overlap (1-280:1-280)
10 20 30 40 50 60
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPFQ
:: : :::::::::.::::.: :.: :::::::::::.:.:.. .:::::::::::
XP_016 MSQERPTFYRQELNKTIWEVPERYQNLSPVGSGAYGSVCAAFDTKTGLRVAVKKLSRPFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 SLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKCQ
:.:::.:::::::::::.::::::::::::::: :.:.:..::::: :::::::::::::
XP_016 SIIHAKRTYRELRLLKHMKHENVIGLLDVFTPARSLEEFNDVYLVTHLMGADLNNIVKCQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 ALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEMT
:.:.:::::.::.:::::::::: ::::::::::.::::::::.::::::::..:.:::
XP_016 KLTDDHVQFLIYQILRGLKYIHSADIIHRDLKPSNLAVNEDCELKILDFGLARHTDDEMT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVVG
::::::::::::::::::::::::::::::::::::: :..::::.:.::::: :...::
XP_016 GYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLTGRTLFPGTDHIDQLKLILRLVG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 TPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSAA
::. :.: ::::: ::.::::: ::. .....: :::::
XP_016 TPGAELLKKISSESARNYIQSLTQMPKMNFANVFIGANPLGSQSVAQPGELFYLLSCDPG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 EALAHAYFSQYHDPEDEPEAEPYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPGSL
XP_016 KCQHSRDCPRHEGELGLHISCTQTEMQR
310 320
>>NP_002745 (OMIM: 602899) mitogen-activated protein kin (365 aa)
initn: 1362 init1: 908 opt: 1485 Z-score: 655.1 bits: 129.8 E(85289): 9.5e-30
Smith-Waterman score: 1485; 60.5% identity (86.2% similar) in 347 aa overlap (5-350:6-351)
10 20 30 40 50
pF1KB8 MSGPRAGFYRQELNKTVWEVPQRLQGLRPVGSGAYGSVCSAYDARLRQKVAVKKLSRPF
. :::.:..:::.::.:. . :::::::::::: : : .:::.:::::::
NP_002 MSLIRKKGFYKQDVNKTAWELPKTYVSPTHVGSGAYGSVCSAIDKRSGEKVAIKKLSRPF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 QSLIHARRTYRELRLLKHLKHENVIGLLDVFTPATSIEDFSEVYLVTTLMGADLNNIVKC
:: : :.:.:::: ::::..::::::::::::::.:...: . ::: .: .::..:.
NP_002 QSEIFAKRAYRELLLLKHMQHENVIGLLDVFTPASSLRNFYDFYLVMPFMQTDLQKIMGM
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 QALSDEHVQFLVYQLLRGLKYIHSAGIIHRDLKPSNVAVNEDCELRILDFGLARQADEEM
. .:.:..:.::::.:.:::::::::..::::::.:.::::::::.::::::::.:: ::
NP_002 E-FSEEKIQYLVYQMLKGLKYIHSAGVVHRDLKPGNLAVNEDCELKILDFGLARHADAEM
130 140 150 160 170
180 190 200 210 220 230
pF1KB8 TGYVATRWYRAPEIMLNWMHYNQTVDIWSVGCIMAELLQGKALFPGSDYIDQLKRIMEVV
::::.::::::::..:.:::::::::::::::::::.: ::.:: :.::.::: .:..:.
NP_002 TGYVVTRWYRAPEVILSWMHYNQTVDIWSVGCIMAEMLTGKTLFKGKDYLDQLTQILKVT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB8 GTPSPEVLAKISSEHARTYIQSLPPMPQKDLSSIFRGANPLAIDLLGRMLVLDSDQRVSA
:.:. : . :.... :..:::::: :.::....: :.: : ::: .:: :: :.:..:
NP_002 GVPGTEFVQKLNDKAAKSYIQSLPQTPRKDFTQLFPRASPQAADLLEKMLELDVDKRLTA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB8 AEALAHAYFSQYHDPEDEPEAE-PYDESVEAKERTLEEWKELTYQEVLSFKPPEPPKPPG
:.::.: .: ..:::.: ::. :.:.:.: .. :..:::. :.:...:.:
NP_002 AQALTHPFFEPFRDPEEETEAQQPFDDSLEHEKLTVDEWKQHIYKEIVNFSPIARKDSRR
300 310 320 330 340 350
360
pF1KB8 SLEIEQ
NP_002 RSGMKL
360
364 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 13:01:04 2016 done: Fri Nov 4 13:01:06 2016
Total Scan time: 9.260 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]