Result of FASTA (omim) for
pFN21AB8335
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8335, 440 aa
1>>>pF1KB8335 440 - 440 aa - 440 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7964+/-0.000354; mu= 15.6325+/- 0.022
mean_var=88.6486+/-18.433, 0's: 0 Z-trim(115.6): 182 B-trim: 214 in 1/54
Lambda= 0.136219
statistics sampled from 25957 (26148) to 25957 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.677), E-opt: 0.2 (0.307), width: 16
Scan time: 7.040
The best scores are: opt bits E(85289)
NP_056980 (OMIM: 607070,615444) zinc finger MYND d ( 440) 2968 593.4 3.9e-169
NP_001295308 (OMIM: 607070,615444) zinc finger MYN ( 435) 2716 543.8 3.2e-154
XP_005265273 (OMIM: 607070,615444) PREDICTED: zinc ( 361) 2467 494.9 1.5e-139
NP_787127 (OMIM: 603870) protein CBFA2T3 isoform 2 ( 567) 160 41.6 0.0063
XP_005256380 (OMIM: 603870) PREDICTED: protein CBF ( 628) 160 41.6 0.0068
NP_005178 (OMIM: 603870) protein CBFA2T3 isoform 1 ( 653) 160 41.7 0.0071
>>NP_056980 (OMIM: 607070,615444) zinc finger MYND domai (440 aa)
initn: 2968 init1: 2968 opt: 2968 Z-score: 3157.4 bits: 593.4 E(85289): 3.9e-169
Smith-Waterman score: 2968; 99.3% identity (99.8% similar) in 440 aa overlap (1-440:1-440)
10 20 30 40 50 60
pF1KB8 MGDLELLLPGEAEVLVRGLRSFPLREMGSEGWNQRHENLEKLNMQAILDATVSQGEPIQE
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_056 MGDLELLLPGEAEVLVRGLRSFPLREMGSEGWNQQHENLEKLNMQAILDATVSQGEPIQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPMQELQKQAELME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPMQELQKQAELME
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 FEIALKALSVLRYITDCVDSLSLSTLSRMLSAHNLPCLLVELLEHSPWSRREGGKLQQFE
:::::::::::::::::::::::::::::::.::::::::::::::::::::::::::::
NP_056 FEIALKALSVLRYITDCVDSLSLSTLSRMLSTHNLPCLLVELLEHSPWSRREGGKLQQFE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 GSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRLLKLRAFLTDTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 GSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRLLKLRAFLTDTL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 LDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKWQAIAKHQLQHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 LDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKWQAIAKHQLQHV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 FSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWYCCRECQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 FSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWYCCRECQV
370 380 390 400 410 420
430 440
pF1KB8 KHWEKHGKTCVPAAQGDRAK
::::::::::: ::::::::
NP_056 KHWEKHGKTCVLAAQGDRAK
430 440
>>NP_001295308 (OMIM: 607070,615444) zinc finger MYND do (435 aa)
initn: 2735 init1: 1429 opt: 2716 Z-score: 2889.9 bits: 543.8 E(85289): 3.2e-154
Smith-Waterman score: 2722; 92.4% identity (94.2% similar) in 447 aa overlap (1-440:1-435)
10 20 30 40 50 60
pF1KB8 MGDLELLLPGEAEVLVRGLRSFPLREMGSEGWNQRHENLEKLNMQAILDATVSQGEPIQE
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
NP_001 MGDLELLLPGEAEVLVRGLRSFPLREMGSEGWNQQHENLEKLNMQAILDATVSQGEPIQE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 LLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHHEASIINLLETV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPMQELQKQAELME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPMQELQKQAELME
130 140 150 160 170 180
190 200 210 220 230
pF1KB8 FEIALKALSVLRYITDCVD---SLS----LSTLSRMLSAHNLPCLLVELLEHSPWSRREG
::::::::::::::::::: :.: :. :.:. : . : .. ::
NP_001 FEIALKALSVLRYITDCVDRQWSVSQPPQLAHLKRIQRLHPV-CWFL-----SP------
190 200 210 220
240 250 260 270 280 290
pF1KB8 GKLQQFEGSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRLLKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKLQQFEGSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRLLKLR
230 240 250 260 270 280
300 310 320 330 340 350
pF1KB8 AFLTDTLLDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKWQAIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AFLTDTLLDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKWQAIA
290 300 310 320 330 340
360 370 380 390 400 410
pF1KB8 KHQLQHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHQLQHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQNEWY
350 360 370 380 390 400
420 430 440
pF1KB8 CCRECQVKHWEKHGKTCVPAAQGDRAK
:::::::::::::::::: ::::::::
NP_001 CCRECQVKHWEKHGKTCVLAAQGDRAK
410 420 430
>>XP_005265273 (OMIM: 607070,615444) PREDICTED: zinc fin (361 aa)
initn: 2467 init1: 2467 opt: 2467 Z-score: 2626.6 bits: 494.9 E(85289): 1.5e-139
Smith-Waterman score: 2467; 99.4% identity (99.7% similar) in 361 aa overlap (80-440:1-361)
50 60 70 80 90 100
pF1KB8 ATVSQGEPIQELLVTHGKVPTLVEELIAVEMWKQKVFPVFCRVEDFKPQNTFPIYMVVHH
::::::::::::::::::::::::::::::
XP_005 MWKQKVFPVFCRVEDFKPQNTFPIYMVVHH
10 20 30
110 120 130 140 150 160
pF1KB8 EASIINLLETVFFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EASIINLLETVFFHKEVCESAEDTVLDLVDYCHRKLTLLVAQSGCGGPPEGEGSQDSNPM
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB8 QELQKQAELMEFEIALKALSVLRYITDCVDSLSLSTLSRMLSAHNLPCLLVELLEHSPWS
::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::
XP_005 QELQKQAELMEFEIALKALSVLRYITDCVDSLSLSTLSRMLSTHNLPCLLVELLEHSPWS
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB8 RREGGKLQQFEGSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RREGGKLQQFEGSRWHTVAPSEQQKLSKLDGQVWIALYNLLLSPEAQARYCLTSFAKGRL
160 170 180 190 200 210
290 300 310 320 330 340
pF1KB8 LKLRAFLTDTLLDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LKLRAFLTDTLLDQLPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPEIWERLERENRGKW
220 230 240 250 260 270
350 360 370 380 390 400
pF1KB8 QAIAKHQLQHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAIAKHQLQHVFSPSEQDLRLQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSRCQ
280 290 300 310 320 330
410 420 430 440
pF1KB8 NEWYCCRECQVKHWEKHGKTCVPAAQGDRAK
:::::::::::::::::::::: ::::::::
XP_005 NEWYCCRECQVKHWEKHGKTCVLAAQGDRAK
340 350 360
>>NP_787127 (OMIM: 603870) protein CBFA2T3 isoform 2 [Ho (567 aa)
initn: 153 init1: 125 opt: 160 Z-score: 173.5 bits: 41.6 E(85289): 0.0063
Smith-Waterman score: 171; 30.3% identity (50.8% similar) in 122 aa overlap (334-439:396-515)
310 320 330 340 350 360
pF1KB8 LPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPE-IWERLERE-NRGKWQAIAKHQLQHVF
.:: ::.. :. :. : ::.. .::..
NP_787 AARPRSSSAGPEGPQLDVPREFLPRTLTGYVPEDIWRKAEEAVNEVKRQAMS--ELQKAV
370 380 390 400 410 420
370 380 390 400
pF1KB8 SPSEQDLR--------------LQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSR
: .:. . .:.: : : :.. : :. .::. ::
NP_787 SDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSG
430 440 450 460 470 480
410 420 430 440
pF1KB8 CQNEWYCCRECQVKHWEKHGKTCVPAAQGDRAK
:. :: :: . :::: ..: . :: :
NP_787 CNAARYCGSFCQHRDWEKHHHVCGQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPS
490 500 510 520 530 540
NP_787 EAGSAGPSRPGSPSPPGPLDTVPR
550 560
>>XP_005256380 (OMIM: 603870) PREDICTED: protein CBFA2T3 (628 aa)
initn: 153 init1: 125 opt: 160 Z-score: 172.9 bits: 41.6 E(85289): 0.0068
Smith-Waterman score: 171; 30.3% identity (50.8% similar) in 122 aa overlap (334-439:457-576)
310 320 330 340 350 360
pF1KB8 LPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPE-IWERLERE-NRGKWQAIAKHQLQHVF
.:: ::.. :. :. : ::.. .::..
XP_005 AARPRSSSAGPEGPQLDVPREFLPRTLTGYVPEDIWRKAEEAVNEVKRQAMS--ELQKAV
430 440 450 460 470 480
370 380 390 400
pF1KB8 SPSEQDLR--------------LQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSR
: .:. . .:.: : : :.. : :. .::. ::
XP_005 SDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSG
490 500 510 520 530 540
410 420 430 440
pF1KB8 CQNEWYCCRECQVKHWEKHGKTCVPAAQGDRAK
:. :: :: . :::: ..: . :: :
XP_005 CNAARYCGSFCQHRDWEKHHHVCGQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPS
550 560 570 580 590 600
XP_005 EAGSAGPSRPGSPSPPGPLDTVPR
610 620
>>NP_005178 (OMIM: 603870) protein CBFA2T3 isoform 1 [Ho (653 aa)
initn: 181 init1: 125 opt: 160 Z-score: 172.6 bits: 41.7 E(85289): 0.0071
Smith-Waterman score: 171; 30.3% identity (50.8% similar) in 122 aa overlap (334-439:482-601)
310 320 330 340 350 360
pF1KB8 LPNLAHLQSFLAHLTLTETQPPKKDLVLEQIPE-IWERLERE-NRGKWQAIAKHQLQHVF
.:: ::.. :. :. : ::.. .::..
NP_005 AARPRSSSAGPEGPQLDVPREFLPRTLTGYVPEDIWRKAEEAVNEVKRQAMS--ELQKAV
460 470 480 490 500
370 380 390 400
pF1KB8 SPSEQDLR--------------LQARRWAETYRLDVLEAVAPERPRCAYCSAEASKRCSR
: .:. . .:.: : : :.. : :. .::. ::
NP_005 SDAERKAHELITTERAKMERALAEAKRQASEDALTVINQQEDSSESCWNCGRKASETCSG
510 520 530 540 550 560
410 420 430 440
pF1KB8 CQNEWYCCRECQVKHWEKHGKTCVPAAQGDRAK
:. :: :: . :::: ..: . :: :
NP_005 CNAARYCGSFCQHRDWEKHHHVCGQSLQGPTAVVADPVPGPPEAAHSLGPSLPVGAASPS
570 580 590 600 610 620
NP_005 EAGSAGPSRPGSPSPPGPLDTVPR
630 640 650
440 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 11:52:13 2016 done: Fri Nov 4 11:52:14 2016
Total Scan time: 7.040 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]