FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB8300, 463 aa
  1>>>pF1KB8300 463 - 463 aa - 463 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2410+/-0.00121; mu= 12.9476+/- 0.072
 mean_var=75.0978+/-14.856, 0's: 0 Z-trim(101.3): 47  B-trim: 0 in 0/50
 Lambda= 0.148000
 statistics sampled from 6452 (6472) to 6452 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.549), E-opt: 0.2 (0.199), width:  16
 Scan time:  1.940

The best scores are:                                      opt bits E(32554)
CCDS42588.1 RUVBL2 gene_id:10856|Hs108|chr19       ( 463) 2907 630.6  1e-180
CCDS3047.1 RUVBL1 gene_id:8607|Hs108|chr3          ( 456)  747 169.4 6.8e-42
CCDS82833.1 RUVBL1 gene_id:8607|Hs108|chr3         ( 315)  545 126.3 4.7e-29


>>CCDS42588.1 RUVBL2 gene_id:10856|Hs108|chr19            (463 aa)
 initn: 2907 init1: 2907 opt: 2907  Z-score: 3358.0  bits: 630.6 E(32554): 1e-180
Smith-Waterman score: 2907; 100.0% identity (100.0% similar) in 463 aa overlap (1-463:1-463)

               10        20        30        40        50        60
pF1KB8 MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVL
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB8 EMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 EMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALT
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB8 QAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 QAFRRSIGVRIKEETEIIEGEVVEIQIDRPATGTGSKVGKLTLKTTEMETIYDLGTKMIE
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB8 SLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 SLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKRKEVVH
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB8 TVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 TVSLHEIDVINSRTQGFLALFSGDTGEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDE
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB8 VHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTT
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 VHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGTSYQSPHGIPIDLLDRLLIVSTT
              310       320       330       340       350       360

              370       380       390       400       410       420
pF1KB8 PYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS42 PYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTE
              370       380       390       400       410       420

              430       440       450       460   
pF1KB8 VQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS
       :::::::::::::::::::::::::::::::::::::::::::
CCDS42 VQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS
              430       440       450       460   

>>CCDS3047.1 RUVBL1 gene_id:8607|Hs108|chr3               (456 aa)
 initn: 1229 init1: 483 opt: 747  Z-score: 865.6  bits: 169.4 E(32554): 6.8e-42
Smith-Waterman score: 1267; 43.0% identity (73.7% similar) in 456 aa overlap (9-451:2-455)

               10        20        30        40        50        60
pF1KB8 MATVTATTKVPEIRDVTRIERIGAHSHIRGLGLDDALEPRQASQGMVGQLAARRAAGVVL
               :. :....:. .::..:::..:::::..   .::..:.:::  ::.: ::..
CCDS30        MKIEEVKSTTKTQRIASHSHVKGLGLDESGLAKQAASGLVGQENAREACGVIV
                      10        20        30        40        50   

               70        80        90       100       110       120
pF1KB8 EMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALT
       :.:.  :.::::::.:: :::::::.:...:: ::  .::  ..:::..: :..:::.: 
CCDS30 ELIKSKKMAGRAVLLAGPPGTGKTALALAIAQELGSKVPFCPMVGSEVYSTEIKKTEVLM
            60        70        80        90       100       110   

              130       140          150       160         170     
pF1KB8 QAFRRSIGVRIKEETEIIEGEVVEI---QIDRPATGTGSKVGKLT--LKTTEMETIYDLG
       . :::.::.::::  :. ::::.:.   . . :  : :. ....   :::..      : 
CCDS30 ENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGYGKTISHVIIGLKTAKGTKQLKLD
           120       130       140       150       160       170   

         180       190       200       210       220       230     
pF1KB8 TKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRARDYDAMGSQTKFVQCPDGELQKR
        ...::: :..:.::::: :.  .: ... ::  : : ..:  . .  .:  : :...:.
CCDS30 PSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYATEFDLEAEE--YVPLPKGDVHKK
           180       190       200       210         220       230 

         240       250       260              270       280        
pF1KB8 KEVVHTVSLHEIDVINSRTQGFLALFS--GDT-----GEIKSEVREQINAKVAEWREEGK
       ::... :.::..:: :.: ::   ..:  :.       :: ...: .::  : .. ..: 
CCDS30 KEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKKTEITDKLRGEINKVVNKYIDQGI
             240       250       260       270       280       290 

      290       300       310       320       330        340       
pF1KB8 AEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLIMATNRGITRIRGT-SYQSPHGIP
       ::..:::::.::::::::: :..:.:::::..::..:.:.:::   :::: .  ::::::
CCDS30 AELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVIFASNRGNCVIRGTEDITSPHGIP
             300       310       320       330       340       350 

       350       360       370       380       390       400       
pF1KB8 IDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSEDAYTVLTRIGLETSLRYAIQLIT
       .:::::..:. :  :. .. :::..:: . : ...::.: . : .:: .:.:::..::.:
CCDS30 LDLLDRVMIIRTMLYTPQEMKQIIKIRAQTEGINISEEALNHLGEIGTKTTLRYSVQLLT
             360       370       380       390       400       410 

       410       420       430       440       450       460   
pF1KB8 AASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMKEYQDAFLFNELKGETMDTS
        :.:. .      .. . ....  :: : . :.. . . :: ..            
CCDS30 PANLLAKINGKDSIEKEHVEEISELFYDAKSSAKILADQQDKYMK           
             420       430       440       450                 

>>CCDS82833.1 RUVBL1 gene_id:8607|Hs108|chr3              (315 aa)
 initn: 886 init1: 310 opt: 545  Z-score: 635.1  bits: 126.3 E(32554): 4.7e-29
Smith-Waterman score: 895; 45.6% identity (73.4% similar) in 316 aa overlap (68-370:1-314)

        40        50        60        70        80        90       
pF1KB8 EPRQASQGMVGQLAARRAAGVVLEMIREGKIAGRAVLIAGQPGTGKTAIAMGMAQALGPD
                                     .::::::.:: :::::::.:...:: ::  
CCDS82                               MAGRAVLLAGPPGTGKTALALAIAQELGSK
                                             10        20        30

       100       110       120       130       140          150    
pF1KB8 TPFTAIAGSEIFSLEMSKTEALTQAFRRSIGVRIKEETEIIEGEVVEI---QIDRPATGT
       .::  ..:::..: :..:::.: . :::.::.::::  :. ::::.:.   . . :  : 
CCDS82 VPFCPMVGSEVYSTEIKKTEVLMENFRRAIGLRIKETKEVYEGEVTELTPCETENPMGGY
               40        50        60        70        80        90

          160         170       180       190       200       210  
pF1KB8 GSKVGKLT--LKTTEMETIYDLGTKMIESLTKDKVQAGDVITIDKATGKISKLGRSFTRA
       :. ....   :::..      :  ...::: :..:.::::: :.  .: ... ::  : :
CCDS82 GKTISHVIIGLKTAKGTKQLKLDPSIFESLQKERVEAGDVIYIEANSGAVKRQGRCDTYA
              100       110       120       130       140       150

            220       230       240       250       260            
pF1KB8 RDYDAMGSQTKFVQCPDGELQKRKEVVHTVSLHEIDVINSRTQGFLALFS--GDT-----
        ..:  . .  .:  : :...:.::... :.::..:: :.: ::   ..:  :.      
CCDS82 TEFDLEAEE--YVPLPKGDVHKKKEIIQDVTLHDLDVANARPQGGQDILSMMGQLMKPKK
                160       170       180       190       200        

         270       280       290       300       310       320     
pF1KB8 GEIKSEVREQINAKVAEWREEGKAEIIPGVLFIDEVHMLDIESFSFLNRALESDMAPVLI
        :: ...: .::  : .. ..: ::..:::::.::::::::: :..:.:::::..::..:
CCDS82 TEITDKLRGEINKVVNKYIDQGIAELVPGVLFVDEVHMLDIECFTYLHRALESSIAPIVI
      210       220       230       240       250       260        

         330        340       350       360       370       380    
pF1KB8 MATNRGITRIRGT-SYQSPHGIPIDLLDRLLIVSTTPYSEKDTKQILRIRCEEEDVEMSE
       .:.:::   :::: .  ::::::.:::::..:. :  :. .. ::.              
CCDS82 FASNRGNCVIRGTEDITSPHGIPLDLLDRVMIIRTMLYTPQEMKQVP             
      270       280       290       300       310                  

          390       400       410       420       430       440    
pF1KB8 DAYTVLTRIGLETSLRYAIQLITAASLVCRKRKGTEVQVDDIKRVYSLFLDESRSTQYMK




463 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 11:30:13 2016 done: Fri Nov  4 11:30:13 2016
 Total Scan time:  1.940 Total Display time:  0.000

Function used was FASTA [36.3.4 Apr, 2011]