Result of FASTA (omim) for
pFN21AB8225
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8225, 142 aa
1>>>pF1KB8225 142 - 142 aa - 142 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4913+/-0.000355; mu= 12.3341+/- 0.022
mean_var=92.8119+/-18.187, 0's: 0 Z-trim(115.1): 14 B-trim: 262 in 1/52
Lambda= 0.133129
statistics sampled from 25345 (25358) to 25345 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.297), width: 16
Scan time: 4.760
The best scores are: opt bits E(85289)
NP_776170 (OMIM: 609768) biogenesis of lysosome-re ( 142) 873 177.0 9.2e-45
NP_001269368 (OMIM: 609768) biogenesis of lysosome ( 141) 855 173.5 1e-43
NP_001001342 (OMIM: 609768) biogenesis of lysosome ( 99) 605 125.3 2.2e-29
NP_001269366 (OMIM: 609768) biogenesis of lysosome ( 99) 605 125.3 2.2e-29
NP_001269367 (OMIM: 609768) biogenesis of lysosome ( 99) 605 125.3 2.2e-29
XP_016871591 (OMIM: 609768) PREDICTED: biogenesis ( 114) 547 114.3 5.5e-26
NP_001269365 (OMIM: 609768) biogenesis of lysosome ( 95) 520 109.0 1.8e-24
>>NP_776170 (OMIM: 609768) biogenesis of lysosome-relate (142 aa)
initn: 873 init1: 873 opt: 873 Z-score: 924.6 bits: 177.0 E(85289): 9.2e-45
Smith-Waterman score: 873; 100.0% identity (100.0% similar) in 142 aa overlap (1-142:1-142)
10 20 30 40 50 60
pF1KB8 MAAAAEGVLATRSDEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 MAAAAEGVLATRSDEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_776 EDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQ
70 80 90 100 110 120
130 140
pF1KB8 AAYKLDAYSKKLEAKYKKLEKR
::::::::::::::::::::::
NP_776 AAYKLDAYSKKLEAKYKKLEKR
130 140
>>NP_001269368 (OMIM: 609768) biogenesis of lysosome-rel (141 aa)
initn: 853 init1: 812 opt: 855 Z-score: 905.9 bits: 173.5 E(85289): 1e-43
Smith-Waterman score: 855; 99.3% identity (99.3% similar) in 142 aa overlap (1-142:1-141)
10 20 30 40 50 60
pF1KB8 MAAAAEGVLATRSDEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAAAAEGVLATRSDEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 EDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDYKLLENMNKLTSLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQ
70 80 90 100 110 120
130 140
pF1KB8 AAYKLDAYSKKLEAKYKKLEKR
:::::::::::: :::::::::
NP_001 AAYKLDAYSKKL-AKYKKLEKR
130 140
>>NP_001001342 (OMIM: 609768) biogenesis of lysosome-rel (99 aa)
initn: 605 init1: 605 opt: 605 Z-score: 648.5 bits: 125.3 E(85289): 2.2e-29
Smith-Waterman score: 605; 100.0% identity (100.0% similar) in 99 aa overlap (44-142:1-99)
20 30 40 50 60 70
pF1KB8 DEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLT
::::::::::::::::::::::::::::::
NP_001 MFSKMATYLTGELTATSEDYKLLENMNKLT
10 20 30
80 90 100 110 120 130
pF1KB8 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
40 50 60 70 80 90
140
pF1KB8 AKYKKLEKR
:::::::::
NP_001 AKYKKLEKR
>>NP_001269366 (OMIM: 609768) biogenesis of lysosome-rel (99 aa)
initn: 605 init1: 605 opt: 605 Z-score: 648.5 bits: 125.3 E(85289): 2.2e-29
Smith-Waterman score: 605; 100.0% identity (100.0% similar) in 99 aa overlap (44-142:1-99)
20 30 40 50 60 70
pF1KB8 DEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLT
::::::::::::::::::::::::::::::
NP_001 MFSKMATYLTGELTATSEDYKLLENMNKLT
10 20 30
80 90 100 110 120 130
pF1KB8 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
40 50 60 70 80 90
140
pF1KB8 AKYKKLEKR
:::::::::
NP_001 AKYKKLEKR
>>NP_001269367 (OMIM: 609768) biogenesis of lysosome-rel (99 aa)
initn: 605 init1: 605 opt: 605 Z-score: 648.5 bits: 125.3 E(85289): 2.2e-29
Smith-Waterman score: 605; 100.0% identity (100.0% similar) in 99 aa overlap (44-142:1-99)
20 30 40 50 60 70
pF1KB8 DEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLT
::::::::::::::::::::::::::::::
NP_001 MFSKMATYLTGELTATSEDYKLLENMNKLT
10 20 30
80 90 100 110 120 130
pF1KB8 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
40 50 60 70 80 90
140
pF1KB8 AKYKKLEKR
:::::::::
NP_001 AKYKKLEKR
>>XP_016871591 (OMIM: 609768) PREDICTED: biogenesis of l (114 aa)
initn: 547 init1: 547 opt: 547 Z-score: 587.4 bits: 114.3 E(85289): 5.5e-26
Smith-Waterman score: 547; 95.7% identity (97.8% similar) in 93 aa overlap (44-136:1-93)
20 30 40 50 60 70
pF1KB8 DEPARDDAAVETAEEAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLT
::::::::::::::::::::::::::::::
XP_016 MFSKMATYLTGELTATSEDYKLLENMNKLT
10 20 30
80 90 100 110 120 130
pF1KB8 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLE
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLKYLEMKDIAINISRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLG
40 50 60 70 80 90
140
pF1KB8 AKYKKLEKR
..
XP_016 NRFYFCFDVIKTASCQHILSKHNS
100 110
>>NP_001269365 (OMIM: 609768) biogenesis of lysosome-rel (95 aa)
initn: 520 init1: 520 opt: 520 Z-score: 560.5 bits: 109.0 E(85289): 1.8e-24
Smith-Waterman score: 520; 100.0% identity (100.0% similar) in 85 aa overlap (58-142:11-95)
30 40 50 60 70 80
pF1KB8 EAKEPAEADITELCRDMFSKMATYLTGELTATSEDYKLLENMNKLTSLKYLEMKDIAINI
::::::::::::::::::::::::::::::
NP_001 MRLPRKSLEVATSEDYKLLENMNKLTSLKYLEMKDIAINI
10 20 30 40
90 100 110 120 130 140
pF1KB8 SRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SRNLKDLNQKYAGLQPYLDQINVIEEQVAALEQAAYKLDAYSKKLEAKYKKLEKR
50 60 70 80 90
142 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:43:46 2016 done: Fri Nov 4 10:43:47 2016
Total Scan time: 4.760 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]