Result of FASTA (omim) for
pFN21AB8173
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8173, 358 aa
1>>>pF1KB8173 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.9707+/-0.000287; mu= 11.5231+/- 0.018
mean_var=158.2609+/-31.296, 0's: 0 Z-trim(122.9): 117 B-trim: 0 in 0/58
Lambda= 0.101950
statistics sampled from 41752 (41880) to 41752 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.491), width: 16
Scan time: 9.720
The best scores are: opt bits E(85289)
XP_016877694 (OMIM: 601740) PREDICTED: homeobox pr ( 306) 1007 159.1 1.2e-38
NP_758527 (OMIM: 601740) homeobox protein Meis2 is ( 306) 1007 159.1 1.2e-38
NP_002390 (OMIM: 601740) homeobox protein Meis2 is ( 381) 1007 159.2 1.3e-38
XP_006720588 (OMIM: 601740) PREDICTED: homeobox pr ( 393) 1007 159.3 1.4e-38
NP_733774 (OMIM: 601740) homeobox protein Meis2 is ( 394) 1007 159.3 1.4e-38
XP_016859635 (OMIM: 601739) PREDICTED: homeobox pr ( 246) 994 157.1 3.7e-38
XP_005264382 (OMIM: 601739) PREDICTED: homeobox pr ( 325) 994 157.3 4.5e-38
NP_002389 (OMIM: 601739) homeobox protein Meis1 [H ( 390) 994 157.3 5.2e-38
XP_005264380 (OMIM: 601739) PREDICTED: homeobox pr ( 406) 994 157.4 5.3e-38
NP_733776 (OMIM: 601740) homeobox protein Meis2 is ( 470) 953 151.4 3.8e-36
NP_001207411 (OMIM: 601740) homeobox protein Meis2 ( 470) 953 151.4 3.8e-36
XP_016859634 (OMIM: 601739) PREDICTED: homeobox pr ( 321) 936 148.7 1.7e-35
XP_016859633 (OMIM: 601739) PREDICTED: homeobox pr ( 321) 936 148.7 1.7e-35
XP_005264381 (OMIM: 601739) PREDICTED: homeobox pr ( 400) 936 148.8 1.9e-35
XP_005264379 (OMIM: 601739) PREDICTED: homeobox pr ( 465) 936 148.9 2.2e-35
XP_005264378 (OMIM: 601739) PREDICTED: homeobox pr ( 481) 936 148.9 2.2e-35
XP_006720592 (OMIM: 601740) PREDICTED: homeobox pr ( 255) 913 145.2 1.5e-34
XP_006720590 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 913 145.4 1.8e-34
XP_011519893 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 913 145.4 1.8e-34
NP_758526 (OMIM: 601740) homeobox protein Meis2 is ( 388) 913 145.4 2e-34
XP_006720589 (OMIM: 601740) PREDICTED: homeobox pr ( 389) 913 145.4 2e-34
XP_006720587 (OMIM: 601740) PREDICTED: homeobox pr ( 400) 913 145.4 2e-34
NP_733777 (OMIM: 601740) homeobox protein Meis2 is ( 401) 913 145.4 2e-34
XP_006720586 (OMIM: 601740) PREDICTED: homeobox pr ( 476) 913 145.5 2.3e-34
NP_733775 (OMIM: 601740) homeobox protein Meis2 is ( 477) 913 145.5 2.3e-34
XP_016859632 (OMIM: 601739) PREDICTED: homeobox pr ( 352) 849 136.0 1.3e-31
XP_016859631 (OMIM: 601739) PREDICTED: homeobox pr ( 417) 849 136.0 1.4e-31
XP_016859630 (OMIM: 601739) PREDICTED: homeobox pr ( 433) 849 136.1 1.5e-31
XP_006718957 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 373 65.9 1.5e-10
XP_016873600 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 373 65.9 1.5e-10
XP_011541249 (OMIM: 613066) PREDICTED: homeobox pr ( 339) 373 65.9 1.5e-10
XP_005271700 (OMIM: 613066) PREDICTED: homeobox pr ( 443) 373 66.1 1.8e-10
XP_011541247 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 373 66.1 1.8e-10
NP_071345 (OMIM: 613066) homeobox protein PKNOX2 [ ( 472) 373 66.1 1.8e-10
XP_005271699 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 373 66.1 1.8e-10
XP_011541246 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 373 66.1 1.8e-10
XP_016873599 (OMIM: 613066) PREDICTED: homeobox pr ( 472) 373 66.1 1.8e-10
NP_001273187 (OMIM: 602100) homeobox protein PKNOX ( 319) 368 65.2 2.3e-10
NP_001307623 (OMIM: 602100) homeobox protein PKNOX ( 435) 368 65.3 2.9e-10
NP_004562 (OMIM: 602100) homeobox protein PKNOX1 i ( 436) 368 65.3 2.9e-10
NP_620410 (OMIM: 300411) homeobox protein TGIF2LX ( 241) 268 50.4 5.1e-06
NP_631960 (OMIM: 400025) homeobox protein TGIF2LY ( 185) 262 49.4 7.8e-06
NP_001186444 (OMIM: 607294) homeobox protein TGIF2 ( 237) 256 48.6 1.7e-05
NP_001186443 (OMIM: 607294) homeobox protein TGIF2 ( 237) 256 48.6 1.7e-05
NP_068581 (OMIM: 607294) homeobox protein TGIF2 [H ( 237) 256 48.6 1.7e-05
NP_001186442 (OMIM: 607294) homeobox protein TGIF2 ( 237) 256 48.6 1.7e-05
NP_733796 (OMIM: 142946,602630) homeobox protein T ( 401) 254 48.5 3.1e-05
NP_001265611 (OMIM: 142946,602630) homeobox protei ( 275) 249 47.6 3.9e-05
NP_775300 (OMIM: 142946,602630) homeobox protein T ( 272) 246 47.2 5.2e-05
XP_016881447 (OMIM: 142946,602630) PREDICTED: home ( 272) 246 47.2 5.2e-05
>>XP_016877694 (OMIM: 601740) PREDICTED: homeobox protei (306 aa)
initn: 1077 init1: 659 opt: 1007 Z-score: 815.1 bits: 159.1 E(85289): 1.2e-38
Smith-Waterman score: 1377; 67.8% identity (84.1% similar) in 314 aa overlap (69-358:1-306)
40 50 60 70 80 90
pF1KB8 RPPQPLPPGLDSDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGD
.::::::::::::.::. . : :::
XP_016 MALVFEKCELATCTPREPGVA------GGD
10 20
100 110 120 130 140
pF1KB8 VCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK---------
::::::::::::.::::::.:.:::::::::::::::::::::::::::::
XP_016 VCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFC
30 40 50 60 70 80
150 160 170 180 190
pF1KB8 --------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LG
:::::::::..:::. . : :. .: .: :.: . : :::.:. :.: :
XP_016 HRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAG
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNI
:::::::: :::::::::.::::::.:::::..: .:.: :....:.:::::::::::::
XP_016 TPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNI
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB8 MRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGA
:::::::::.::::::::::::::::::::::::::::::::::::::::::::. .:::
XP_016 MRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGA
210 220 230 240 250 260
320 330 340 350
pF1KB8 AFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
:.::::::.:... . : :...:: : ..::.....:.:::.
XP_016 AYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
270 280 290 300
>>NP_758527 (OMIM: 601740) homeobox protein Meis2 isofor (306 aa)
initn: 1077 init1: 659 opt: 1007 Z-score: 815.1 bits: 159.1 E(85289): 1.2e-38
Smith-Waterman score: 1377; 67.8% identity (84.1% similar) in 314 aa overlap (69-358:1-306)
40 50 60 70 80 90
pF1KB8 RPPQPLPPGLDSDGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGD
.::::::::::::.::. . : :::
NP_758 MALVFEKCELATCTPREPGVA------GGD
10 20
100 110 120 130 140
pF1KB8 VCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK---------
::::::::::::.::::::.:.:::::::::::::::::::::::::::::
NP_758 VCSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFC
30 40 50 60 70 80
150 160 170 180 190
pF1KB8 --------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LG
:::::::::..:::. . : :. .: .: :.: . : :::.:. :.: :
NP_758 HRYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAG
90 100 110 120 130 140
200 210 220 230 240 250
pF1KB8 TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNI
:::::::: :::::::::.::::::.:::::..: .:.: :....:.:::::::::::::
NP_758 TPGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNI
150 160 170 180 190 200
260 270 280 290 300 310
pF1KB8 MRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGA
:::::::::.::::::::::::::::::::::::::::::::::::::::::::. .:::
NP_758 MRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGA
210 220 230 240 250 260
320 330 340 350
pF1KB8 AFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
:.::::::.:... . : :...:: : ..::.....:.:::.
NP_758 AYSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
270 280 290 300
>>NP_002390 (OMIM: 601740) homeobox protein Meis2 isofor (381 aa)
initn: 1231 init1: 659 opt: 1007 Z-score: 813.9 bits: 159.2 E(85289): 1.3e-38
Smith-Waterman score: 1522; 63.8% identity (79.1% similar) in 378 aa overlap (9-358:14-381)
10 20 30 40 50
pF1KB8 MARRYDELPHYPGIVDGPAALASFPETVPAVPGPYGPHRP-PQPLPPGLDS---D
:: : . : : . :: : : :. .: .. : :
NP_002 MDGVGVPASMYGDPHAPRPIPPVHHLNHGPPL--HATQHYGAHAPHPNVMPASMGSAVND
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 GLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAA
.:::.:: ::::::::::::::::::::::.::. . : :::::::::::::::.
NP_002 ALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVA------GGDVCSSDSFNEDIAV
60 70 80 90 100 110
120 130 140 150
pF1KB8 FAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK-----------------GKMPI
::::::.:.::::::::::::::::::::::::::::: :::::
NP_002 FAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRYISCLKGKMPI
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB8 DLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGTPGPSSGGLASQS
::::..:::. . : :. .: .: :.: . : :::.:. :.: ::::::::: ::::
NP_002 DLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGTPGPSSGGHASQS
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB8 GDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAWLFQHLSHPY
:::::.::::::.:::::..: .:.: :....:.::::::::::::::::::::::.:::
NP_002 GDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIMRAWLFQHLTHPY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB8 PSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAAFSPEGQPIGGYT
:::::::::::::::::::::::::::::::::::::::::. .::::.::::::.:...
NP_002 PSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAAYSPEGQPMGSFV
300 310 320 330 340 350
340 350
pF1KB8 -ETQPHVAVRPPG---SVGMSLNLEGEWHYL
. : :...:: : ..::.....:.:::.
NP_002 LDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
360 370 380
>>XP_006720588 (OMIM: 601740) PREDICTED: homeobox protei (393 aa)
initn: 1280 init1: 659 opt: 1007 Z-score: 813.8 bits: 159.3 E(85289): 1.4e-38
Smith-Waterman score: 1570; 63.2% identity (78.9% similar) in 399 aa overlap (5-358:4-393)
10 20 30 40
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETVPAVP-------GP-------YGPHRP-PQ
::::::: :. :: ::.. . :.. .: :: :: : : :.
XP_006 MFLYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN
10 20 30 40 50
50 60 70 80 90
pF1KB8 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV
.: .. : :.:::.:: ::::::::::::::::::::::.::. . :: :::
XP_006 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV
60 70 80 90 100 110
100 110 120 130 140
pF1KB8 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK----------
:::::::::::.::::::.:.:::::::::::::::::::::::::::::
XP_006 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 -------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT
:::::::::..:::. . : :. .: .: :.: . : :::.:. :.: ::
XP_006 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM
::::::: :::::::::.::::::.:::::..: .:.: :....:.::::::::::::::
XP_006 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAA
::::::::.::::::::::::::::::::::::::::::::::::::::::::. .::::
XP_006 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
300 310 320 330 340 350
320 330 340 350
pF1KB8 FSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
.::::::.:... . : :...:: : ..::.....:.:::.
XP_006 YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
360 370 380 390
>>NP_733774 (OMIM: 601740) homeobox protein Meis2 isofor (394 aa)
initn: 1300 init1: 659 opt: 1007 Z-score: 813.7 bits: 159.3 E(85289): 1.4e-38
Smith-Waterman score: 1590; 63.3% identity (79.2% similar) in 403 aa overlap (1-358:1-394)
10 20 30 40
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETVPAVP-------GP-------YGPHRP-PQ
::.:::::::: :. :: ::.. . :.. .: :: :: : : :.
NP_733 MAQRYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN
10 20 30 40 50
50 60 70 80 90
pF1KB8 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV
.: .. : :.:::.:: ::::::::::::::::::::::.::. . :: :::
NP_733 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV
60 70 80 90 100 110
100 110 120 130 140
pF1KB8 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK----------
:::::::::::.::::::.:.:::::::::::::::::::::::::::::
NP_733 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 -------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT
:::::::::..:::. . : :. .: .: :.: . : :::.:. :.: ::
NP_733 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM
::::::: :::::::::.::::::.:::::..: .:.: :....:.::::::::::::::
NP_733 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAA
::::::::.::::::::::::::::::::::::::::::::::::::::::::. .::::
NP_733 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
300 310 320 330 340 350
320 330 340 350
pF1KB8 FSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
.::::::.:... . : :...:: : ..::.....:.:::.
NP_733 YSPEGQPMGSFVLDGQQHMGIRPAGPMSGMGMNMGMDGQWHYM
360 370 380 390
>>XP_016859635 (OMIM: 601739) PREDICTED: homeobox protei (246 aa)
initn: 901 init1: 506 opt: 994 Z-score: 806.0 bits: 157.1 E(85289): 3.7e-38
Smith-Waterman score: 1048; 65.1% identity (82.7% similar) in 249 aa overlap (133-358:1-246)
110 120 130 140
pF1KB8 DSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK-------------
:::::::::::::::::
XP_016 MIQAIQVLRFHLLELEKVHELCDNFCHRYI
10 20 30
150 160 170 180 190 200
pF1KB8 ----GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQNNMWIRDHEDSGSVHLG-TPGPS
:::::::::.::.:: . : :: : .: :: . : :::.:..:.. : :::::
XP_016 SCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTDQPS-WNRDHDDTASTRSGGTPGPS
40 50 60 70 80
210 220 230 240 250 260
pF1KB8 SGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAWL
::: .:.::::::.::::::.::::::.: .:.: :....:.::::::::::::::::::
XP_016 SGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPDKDKKRHKKRGIFPKVATNIMRAWL
90 100 110 120 130 140
270 280 290 300 310 320
pF1KB8 FQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAAFSPE
::::.::::::::::::::::::::::::::::::::::::::::::::. .::. ..:.
XP_016 FQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNPD
150 160 170 180 190 200
330 340 350
pF1KB8 GQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
:::.::.. . : :...: :: ..::....::.:::.
XP_016 GQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
210 220 230 240
>>XP_005264382 (OMIM: 601739) PREDICTED: homeobox protei (325 aa)
initn: 1127 init1: 506 opt: 994 Z-score: 804.5 bits: 157.3 E(85289): 4.5e-38
Smith-Waterman score: 1410; 65.5% identity (83.2% similar) in 333 aa overlap (50-358:2-325)
20 30 40 50 60 70
pF1KB8 ALASFPETVPAVPGPYGPHRPPQPLPPGLDSDGLKREKDEIYG-HPLFPLLALVFEKCEL
..::. . .. : :::::::::.::::::
XP_005 MAQGLRLQGSRRKGRHPLFPLLALIFEKCEL
10 20 30
80 90 100 110 120 130
pF1KB8 ATCSPRDGAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQ
:::.::. . :: ::::::.:::::::.::::.:.:.::::::::::::::::::
XP_005 ATCTPREPGVAG------GDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQ
40 50 60 70 80
140 150 160 170 180
pF1KB8 VLRFHLLELEK-----------------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPD
::::::::::: :::::::::.::.:: . : :: : .: :
XP_005 VLRFHLLELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTD
90 100 110 120 130 140
190 200 210 220 230 240
pF1KB8 QNNMWIRDHEDSGSVHLG-TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLD
: . : :::.:..:.. : :::::::: .:.::::::.::::::.::::::.: .:.: :
XP_005 QPS-WNRDHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPD
150 160 170 180 190 200
250 260 270 280 290 300
pF1KB8 QERRRNKKRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINAR
....:.::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 KDKKRHKKRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINAR
210 220 230 240 250 260
310 320 330 340 350
pF1KB8 RRIVQPMIDQSNRT-GQGAAFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEW
:::::::::::::. .::. ..:.:::.::.. . : :...: :: ..::....::.:
XP_005 RRIVQPMIDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQW
270 280 290 300 310 320
pF1KB8 HYL
::.
XP_005 HYM
>>NP_002389 (OMIM: 601739) homeobox protein Meis1 [Homo (390 aa)
initn: 1192 init1: 506 opt: 994 Z-score: 803.5 bits: 157.3 E(85289): 5.2e-38
Smith-Waterman score: 1535; 61.2% identity (79.2% similar) in 400 aa overlap (1-358:1-390)
10 20 30 40
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETV----PAVPGPYGP----HRPPQP-----L
::.:::.:::: :. :: :... . :... :. .:: :. :. .
NP_002 MAQRYDDLPHYGGM-DGVGIPSTMYGDPHAARSMQPVHHLNHGPPLHSHQYPHTAHTNAM
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 PPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDVCS
:.. : :.:::.:: ::::::::::::.:::::::::.::. . :: :::::
NP_002 APSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPREPGVAG------GDVCS
60 70 80 90 100 110
110 120 130 140
pF1KB8 SDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK------------
:.:::::::.::::.:.:.:::::::::::::::::::::::::::::
NP_002 SESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCHRY
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 -----GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQNNMWIRDHEDSGSVHLG-TPGP
:::::::::.::.:: . : :: : .: :: . : :::.:..:.. : ::::
NP_002 ISCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTDQPS-WNRDHDDTASTRSGGTPGP
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 SSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIMRAW
:::: .:.::::::.::::::.::::::.: .:.: :....:.:::::::::::::::::
NP_002 SSGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPDKDKKRHKKRGIFPKVATNIMRAW
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB8 LFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAAFSP
:::::.::::::::::::::::::::::::::::::::::::::::::::. .::. ..:
NP_002 LFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGTPYNP
300 310 320 330 340 350
330 340 350
pF1KB8 EGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
.:::.::.. . : :...: :: ..::....::.:::.
NP_002 DGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
360 370 380 390
>>XP_005264380 (OMIM: 601739) PREDICTED: homeobox protei (406 aa)
initn: 1172 init1: 506 opt: 994 Z-score: 803.2 bits: 157.4 E(85289): 5.3e-38
Smith-Waterman score: 1515; 61.1% identity (79.0% similar) in 396 aa overlap (5-358:21-406)
10 20 30
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETV----PAVPGPYGP
::.:::: :. :: :... . :... :. .::
XP_005 MAQRRKMESCAFAFEFALNLYDDLPHYGGM-DGVGIPSTMYGDPHAARSMQPVHHLNHGP
10 20 30 40 50
40 50 60 70 80
pF1KB8 ----HRPPQP-----LPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRD
:. :. . :.. : :.:::.:: ::::::::::::.:::::::::.::.
XP_005 PLHSHQYPHTAHTNAMAPSMGSSVNDALKRDKDAIYGHPLFPLLALIFEKCELATCTPRE
60 70 80 90 100 110
90 100 110 120 130 140
pF1KB8 GAGAGLGTPPGGDVCSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLL
. :: ::::::.:::::::.::::.:.:.:::::::::::::::::::::::::
XP_005 PGVAG------GDVCSSESFNEDIAVFAKQIRAEKPLFSSNPELDNLMIQAIQVLRFHLL
120 130 140 150 160 170
150 160 170 180
pF1KB8 ELEK-----------------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQNNMWIR
:::: :::::::::.::.:: . : :: : .: :: . : :
XP_005 ELEKVHELCDNFCHRYISCLKGKMPIDLVIDDREGGSKSDSEDITRSA-NLTDQPS-WNR
180 190 200 210 220 230
190 200 210 220 230 240
pF1KB8 DHEDSGSVHLG-TPGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNK
::.:..:.. : :::::::: .:.::::::.::::::.::::::.: .:.: :....:.:
XP_005 DHDDTASTRSGGTPGPSSGGHTSHSGDNSSEQGDGLDNSVASPSTG-DDDDPDKDKKRHK
240 250 260 270 280 290
250 260 270 280 290 300
pF1KB8 KRGIFPKVATNIMRAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPM
:::::::::::::::::::::.::::::::::::::::::::::::::::::::::::::
XP_005 KRGIFPKVATNIMRAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPM
300 310 320 330 340 350
310 320 330 340 350
pF1KB8 IDQSNRT-GQGAAFSPEGQPIGGYT-ETQPHVAVRPPG---SVGMSLNLEGEWHYL
::::::. .::. ..:.:::.::.. . : :...: :: ..::....::.:::.
XP_005 IDQSNRAVSQGTPYNPDGQPMGGFVMDGQQHMGIRAPGPMSGMGMNMGMEGQWHYM
360 370 380 390 400
>>NP_733776 (OMIM: 601740) homeobox protein Meis2 isofor (470 aa)
initn: 1203 init1: 659 opt: 953 Z-score: 769.8 bits: 151.4 E(85289): 3.8e-36
Smith-Waterman score: 1536; 64.3% identity (78.7% similar) in 389 aa overlap (1-347:1-380)
10 20 30 40
pF1KB8 MARRYDELPHYPGIVDG---PAALASFPETVPAVP-------GP-------YGPHRP-PQ
::.:::::::: :. :: ::.. . :.. .: :: :: : : :.
NP_733 MAQRYDELPHYGGM-DGVGVPASMYGDPHAPRPIPPVHHLNHGPPLHATQHYGAHAPHPN
10 20 30 40 50
50 60 70 80 90
pF1KB8 PLPPGLDS---DGLKREKDEIYGHPLFPLLALVFEKCELATCSPRDGAGAGLGTPPGGDV
.: .. : :.:::.:: ::::::::::::::::::::::.::. . :: :::
NP_733 VMPASMGSAVNDALKRDKDAIYGHPLFPLLALVFEKCELATCTPREPGVAG------GDV
60 70 80 90 100 110
100 110 120 130 140
pF1KB8 CSSDSFNEDIAAFAKQVRSERPLFSSNPELDNLMIQAIQVLRFHLLELEK----------
:::::::::::.::::::.:.:::::::::::::::::::::::::::::
NP_733 CSSDSFNEDIAVFAKQVRAEKPLFSSNPELDNLMIQAIQVLRFHLLELEKVHELCDNFCH
120 130 140 150 160 170
150 160 170 180 190 200
pF1KB8 -------GKMPIDLVIEDRDGGCREDFEDYPASCPSLPDQN-NMWIRDHEDSGSVH-LGT
:::::::::..:::. . : :. .: .: :.: . : :::.:. :.: ::
NP_733 RYISCLKGKMPIDLVIDERDGSSKSDHEELSGSSTNLADHNPSSW-RDHDDATSTHSAGT
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB8 PGPSSGGLASQSGDNSSDQGDGLDTSVASPSSGGEDEDLDQERRRNKKRGIFPKVATNIM
::::::: :::::::::.::::::.:::::..: .:.: :....:.::::::::::::::
NP_733 PGPSSGGHASQSGDNSSEQGDGLDNSVASPGTG-DDDDPDKDKKRQKKRGIFPKVATNIM
240 250 260 270 280 290
270 280 290 300 310
pF1KB8 RAWLFQHLSHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRT-GQGAA
::::::::.::::::::::::::::::::::::::::::::::::::::::::. .::::
NP_733 RAWLFQHLTHPYPSEEQKKQLAQDTGLTILQVNNWFINARRRIVQPMIDQSNRAVSQGAA
300 310 320 330 340 350
320 330 340 350
pF1KB8 FSPEGQPIGGYT-ETQPHVAVRPPGSVGMSLNLEGEWHYL
.::::::.:... . : :...:: : .:
NP_733 YSPEGQPMGSFVLDGQQHMGIRPAGLQSMPGDYVSQGGPMGMSMAQPSYTPPQMTPHPTQ
360 370 380 390 400 410
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:14:35 2016 done: Fri Nov 4 10:14:36 2016
Total Scan time: 9.720 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]