Result of FASTA (omim) for
pFN21AB8156
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8156, 404 aa
1>>>pF1KB8156 404 - 404 aa - 404 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8441+/-0.000402; mu= 16.1369+/- 0.025
mean_var=105.6701+/-21.307, 0's: 0 Z-trim(113.6): 68 B-trim: 0 in 0/53
Lambda= 0.124767
statistics sampled from 22950 (23008) to 22950 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.27), width: 16
Scan time: 5.100
The best scores are: opt bits E(85289)
NP_055241 (OMIM: 605937) sorting nexin-5 isoform a ( 404) 2600 478.8 1e-134
NP_689413 (OMIM: 605937) sorting nexin-5 isoform a ( 404) 2600 478.8 1e-134
NP_001269383 (OMIM: 605937) sorting nexin-5 isofor ( 299) 1903 353.2 4.7e-97
NP_689419 (OMIM: 606098) sorting nexin-6 isoform b ( 418) 1772 329.8 7.6e-90
XP_006720287 (OMIM: 606098) PREDICTED: sorting nex ( 381) 1409 264.4 3.3e-70
NP_067072 (OMIM: 606098) sorting nexin-6 isoform a ( 290) 1253 236.2 7.7e-62
NP_001265128 (OMIM: 605929) sorting nexin-2 isofor ( 402) 201 47.0 9.8e-05
NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 ( 519) 201 47.1 0.00012
XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387) 179 43.0 0.0015
XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387) 179 43.0 0.0015
XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387) 179 43.0 0.0015
XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387) 179 43.0 0.0015
XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387) 179 43.0 0.0015
NP_003090 (OMIM: 601272) sorting nexin-1 isoform a ( 522) 180 43.3 0.0016
NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451) 179 43.1 0.0017
NP_001229862 (OMIM: 601272) sorting nexin-1 isofor ( 557) 180 43.3 0.0017
XP_005254668 (OMIM: 601272) PREDICTED: sorting nex ( 399) 169 41.2 0.0053
NP_683758 (OMIM: 601272) sorting nexin-1 isoform b ( 457) 169 41.3 0.0059
>>NP_055241 (OMIM: 605937) sorting nexin-5 isoform a [Ho (404 aa)
initn: 2600 init1: 2600 opt: 2600 Z-score: 2539.7 bits: 478.8 E(85289): 1e-134
Smith-Waterman score: 2600; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE
310 320 330 340 350 360
370 380 390 400
pF1KB8 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
::::::::::::::::::::::::::::::::::::::::::::
NP_055 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
370 380 390 400
>>NP_689413 (OMIM: 605937) sorting nexin-5 isoform a [Ho (404 aa)
initn: 2600 init1: 2600 opt: 2600 Z-score: 2539.7 bits: 478.8 E(85289): 1e-134
Smith-Waterman score: 2600; 100.0% identity (100.0% similar) in 404 aa overlap (1-404:1-404)
10 20 30 40 50 60
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTVHTKTTLPTFQS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 PEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 EMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 ADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYML
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 NIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEE
310 320 330 340 350 360
370 380 390 400
pF1KB8 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
::::::::::::::::::::::::::::::::::::::::::::
NP_689 LINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
370 380 390 400
>>NP_001269383 (OMIM: 605937) sorting nexin-5 isoform b (299 aa)
initn: 1903 init1: 1903 opt: 1903 Z-score: 1863.3 bits: 353.2 E(85289): 4.7e-97
Smith-Waterman score: 1903; 100.0% identity (100.0% similar) in 299 aa overlap (106-404:1-299)
80 90 100 110 120 130
pF1KB8 HDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAV
::::::::::::::::::::::::::::::
NP_001 MQKLGEGEGSMTKEEFAKMKQELEAEYLAV
10 20 30
140 150 160 170 180 190
pF1KB8 FKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSAD
40 50 60 70 80 90
200 210 220 230 240 250
pF1KB8 EVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLA
100 110 120 130 140 150
260 270 280 290 300 310
pF1KB8 LEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEPTVIKKYLLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKA
160 170 180 190 200 210
320 330 340 350 360 370
pF1KB8 LIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIDYENSNKALDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKN
220 230 240 250 260 270
380 390 400
pF1KB8 LIEMSELEIKHARNNVSLLQSCIDLFKNN
:::::::::::::::::::::::::::::
NP_001 LIEMSELEIKHARNNVSLLQSCIDLFKNN
280 290
>>NP_689419 (OMIM: 606098) sorting nexin-6 isoform b [Ho (418 aa)
initn: 1767 init1: 1739 opt: 1772 Z-score: 1734.0 bits: 329.8 E(85289): 7.6e-90
Smith-Waterman score: 1772; 64.5% identity (90.0% similar) in 400 aa overlap (5-404:21-417)
10 20 30 40
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDK
:..: .::::. :....:::. : .::.:: ::::::::
NP_689 MRACAGPRLGAAMMEGLDDGPDFL--SEEDRG-LKAINVDLQSDAALQVDISDALSERDK
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE
::::::::..::.:.. ::::.::::.:.::::...:. :::: :::::: .::::. ::
NP_689 VKFTVHTKSSLPNFKQNEFSVVRQHEEFIWLHDSFVENEDYAGYIIPPAPPRPDFDASRE
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB8 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV
:.:::::::::::::::.::::::::::::.:::::. ::::: :...::.: .: ::::
NP_689 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB8 FLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIK
::::.:::::: :: :: . :::..::::: :. .:::.::::::.:..::..:.::.:
NP_689 FLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVK
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB8 DSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVS
:. .:.:.::::::..:::: . .. :..:. .. : : :..:::.:::.: ::.:.:::
NP_689 DASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB8 SDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQ
.::::::..::.::. . .:::::::::...:.::::.:::::::: :.::: ::. ::
NP_689 ADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQ
300 310 320 330 340 350
350 360 370 380 390 400
pF1KB8 ECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
::::::..:::::.:::.:: .:::::::::.:..:::.:::..:..:::.:. .....
NP_689 LCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGD
360 370 380 390 400 410
NP_689 T
>>XP_006720287 (OMIM: 606098) PREDICTED: sorting nexin-6 (381 aa)
initn: 1561 init1: 1409 opt: 1409 Z-score: 1381.4 bits: 264.4 E(85289): 3.3e-70
Smith-Waterman score: 1510; 59.0% identity (81.5% similar) in 400 aa overlap (5-404:21-380)
10 20 30 40
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDK
:..: .::::. :....:::. : .::.:: ::::::::
XP_006 MRACAGPRLGAAMMEGLDDGPDFL--SEEDRG-LKAINVDLQSDAALQVDISDALSERDK
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 VKFTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPRE
:::::::: ::::: .::::. ::
XP_006 VKFTVHTK-------------------------------------IPPAPPRPDFDASRE
60 70 80
110 120 130 140 150 160
pF1KB8 KMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHV
:.:::::::::::::::.::::::::::::.:::::. ::::: :...::.: .: ::::
XP_006 KLQKLGEGEGSMTKEEFTKMKQELEAEYLAIFKKTVAMHEVFLCRVAAHPILRRDLNFHV
90 100 110 120 130 140
170 180 190 200 210 220
pF1KB8 FLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIK
::::.:::::: :: :: . :::..::::: :. .:::.::::::.:..::..:.::.:
XP_006 FLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDVDDFFEHERTFLLEYHNRVK
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB8 DSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKYLLKVAELFEKLRKVEGRVS
:. .:.:.::::::..:::: . .. :..:. .. : : :..:::.:::.: ::.:.:::
XP_006 DASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKFFLKVSELFDKTRKIEARVS
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB8 SDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQ
.::::::..::.::. . .:::::::::...:.::::.:::::::: :.::: ::. ::
XP_006 ADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKALDKARAKNKDVLQAETSQQ
270 280 290 300 310 320
350 360 370 380 390 400
pF1KB8 ECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
::::::..:::::.:::.:: .:::::::::.:..:::.:::..:..:::.:. .....
XP_006 LCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELKHAKGNLQLLQNCLAVLNGD
330 340 350 360 370 380
XP_006 T
>>NP_067072 (OMIM: 606098) sorting nexin-6 isoform a [Ho (290 aa)
initn: 1253 init1: 1253 opt: 1253 Z-score: 1231.2 bits: 236.2 E(85289): 7.7e-62
Smith-Waterman score: 1253; 63.7% identity (90.0% similar) in 289 aa overlap (116-404:1-289)
90 100 110 120 130 140
pF1KB8 AGLIIPPAPTKPDFDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEV
::::::.::::::::::::.:::::. :::
NP_067 MTKEEFTKMKQELEAEYLAIFKKTVAMHEV
10 20 30
150 160 170 180 190 200
pF1KB8 FLQRLSSHPVLSKDRNFHVFLEYDQDLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEV
:: :...::.: .: ::::::::.:::::: :: :: . :::..::::: :. .:::.:
NP_067 FLCRVAAHPILRRDLNFHVFLEYNQDLSVRGKNKKEKLEDFFKNMVKSADGVIVSGVKDV
40 50 60 70 80 90
210 220 230 240 250 260
pF1KB8 DDFFEQEKNFLINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLALEEPTVIKKY
:::::.:..::..:.::.::. .:.:.::::::..:::: . .. :..:. .. : : :.
NP_067 DDFFEHERTFLLEYHNRVKDASAKSDRMTRSHKSAADDYNRIGSSLYALGTQDSTDICKF
100 110 120 130 140 150
270 280 290 300 310 320
pF1KB8 LLKVAELFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKA
.:::.:::.: ::.:.:::.::::::..::.::. . .:::::::::...:.::::.:::
NP_067 FLKVSELFDKTRKIEARVSADEDLKLSDLLKYYLRESQAAKDLLYRRSRSLVDYENANKA
160 170 180 190 200 210
330 340 350 360 370 380
pF1KB8 LDKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIK
::::: :.::: ::. :: ::::::..:::::.:::.:: .:::::::::.:..:::.:
NP_067 LDKARAKNKDVLQAETSQQLCCQKFEKISESAKQELIDFKTRRVAAFRKNLVELAELELK
220 230 240 250 260 270
390 400
pF1KB8 HARNNVSLLQSCIDLFKNN
::..:..:::.:. .....
NP_067 HAKGNLQLLQNCLAVLNGDT
280 290
>>NP_001265128 (OMIM: 605929) sorting nexin-2 isoform 2 (402 aa)
initn: 236 init1: 149 opt: 201 Z-score: 206.0 bits: 47.0 E(85289): 9.8e-05
Smith-Waterman score: 360; 26.8% identity (57.6% similar) in 396 aa overlap (14-381:8-378)
10 20 30 40 50
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDP-SLQIDIPDALSERDKVK----FTVHTKTTL
:::. . . . : : ...: . : . : .. . : :::.:
NP_001 MSAPVIFDRSR-EEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSL
10 20 30 40 50
60 70 80 90 100 110
pF1KB8 PTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKLGEGEGS
:.. :::: :. ::. ::. : ..: :.:::: : .. : : :. :. .
NP_001 SMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEK-SIVG----MTKVKVGKED
60 70 80 90 100
120 130 140 150 160 170
pF1KB8 MTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYDQDLSVR
.. ::.. .. .. : .::: .::.: .: ... ::: ...: :
NP_001 SSSTEFVEKRR--------------AALERYLQRTVKHPTLLQDPDLRQFLE-SSELP-R
110 120 130 140 150
180 190 200 210 220 230
pF1KB8 RKNTKEMFG-GFFKSVVKSADEVLFTGVK--EVDDFFEQEKNFLINYYNRIKDSCVKADK
::. . : :... : :.:: : .: : : .::.... . : .... :...
NP_001 AVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEA
160 170 180 190 200 210
240 250 260 270 280
pF1KB8 MTRSHKNVADDYIHTAACLHSLAL----EEPTVIKKYLLKVAELFEKLRKVEGRVSSDED
.. .:... . ::: .: :. :. :.... : ..::. ::. ... . . .
NP_001 LVCHRKELSAN---TAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADF
220 230 240 250 260
290 300 310 320 330
pF1KB8 LKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKAL----------------DKARLK
..::: :. : :.: .. .: : .:... .: :: .
NP_001 YMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMMVANKPDKIQQA
270 280 290 300 310 320
340 350 360 370 380 390
pF1KB8 SKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVS
..... ::. :. . :::.:.. ..:. :...:: :. .:.. :
NP_001 KNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIK
330 340 350 360 370 380
400
pF1KB8 LLQSCIDLFKNN
NP_001 YWEAFLPEAKAIA
390 400
>>NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 [Ho (519 aa)
initn: 236 init1: 149 opt: 201 Z-score: 204.5 bits: 47.1 E(85289): 0.00012
Smith-Waterman score: 360; 26.8% identity (57.6% similar) in 396 aa overlap (14-381:125-495)
10 20 30 40
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDP-SLQIDIPDALSER
:::. . . . : : ...: . : .
NP_003 EPSPAVTPVTPTTLIAPRIESKSMSAPVIFDRSR-EEIEEEANGDIFDIEIGVSDPEKVG
100 110 120 130 140 150
50 60 70 80 90
pF1KB8 DKVK----FTVHTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPD
: .. . : :::.: :.. :::: :. ::. ::. : ..: :.:::: : .
NP_003 DGMNAYMAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEK-S
160 170 180 190 200 210
100 110 120 130 140 150
pF1KB8 FDGPREKMQKLGEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSK
. : : :. :. . .. ::.. .. .. : .::: .::.: .
NP_003 IVG----MTKVKVGKEDSSSTEFVEKRR--------------AALERYLQRTVKHPTLLQ
220 230 240 250
160 170 180 190 200 210
pF1KB8 DRNFHVFLEYDQDLSVRRKNTKEMFG-GFFKSVVKSADEVLFTGVK--EVDDFFEQEKNF
: ... ::: ...: : ::. . : :... : :.:: : .: : : .::....
NP_003 DPDLRQFLE-SSELP-RAVNTQALSGAGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQ
260 270 280 290 300 310
220 230 240 250 260 270
pF1KB8 LINYYNRIKDSCVKADKMTRSHKNVADDYIHTAACLHSLAL----EEPTVIKKYLLKVAE
. : .... :... .. .:... . ::: .: :. :. :.... : ..::
NP_003 FENLDQQLRKLHVSVEALVCHRKELSAN---TAAFAKSAAMLGNSEDHTALSRALSQLAE
320 330 340 350 360
280 290 300 310 320
pF1KB8 LFEKLRKVEGRVSSDEDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKAL-----
. ::. ... . . . ..::: :. : :.: .. .: : .:... .:
NP_003 VEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDHRMKCWQKWEDAQITLLKKRE
370 380 390 400 410 420
330 340 350 360 370
pF1KB8 -----------DKARLKSKDVKLAEAHQQECCQKFEQLSESAKEELINFKRKRVAAFRKN
:: . ..... ::. :. . :::.:.. ..:. :...:: :.
NP_003 AEAKMMVANKPDKIQQAKNEIREWEAKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTV
430 440 450 460 470 480
380 390 400
pF1KB8 LIEMSELEIKHARNNVSLLQSCIDLFKNN
.:.. :
NP_003 IIKYLESLVQTQQQLIKYWEAFLPEAKAIA
490 500 510
>>XP_006710741 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 213 init1: 95 opt: 179 Z-score: 184.8 bits: 43.0 E(85289): 0.0015
Smith-Waterman score: 219; 21.5% identity (53.5% similar) in 391 aa overlap (9-396:20-369)
10 20 30 40
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTV
: . ::. :... . .. .: .. ... . . .
XP_006 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVD-EPESHVTTIETF-----ITYRI
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 HTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKL
:::. :.: :: : :...::.::. : :. . ::::: : : : :..
XP_006 ITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMVERF---
60 70 80 90 100
110 120 130 140 150 160
pF1KB8 GEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYD
...: .:.. :. : ::.:...::.:. ...:..:: .
XP_006 --------NDDF------IETRRKALHK--------FLNRIADHPTLTFNEDFKIFLTAQ
110 120 130 140
170 180 190 200 210 220
pF1KB8 Q-DLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCV
.:: ..:. ... . ..: :. . :::. . : . .::. . ..:.
XP_006 AWELSSHKKQGPGLLSRMGQTVRAVASSM--RGVKNRPEEFMEMNNFIELFSQKINLIDK
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB8 KADKMTRSHKNVADDYIHTAACLHSL--ALEEPTVIKKYLLKVAELFEKLRKVEGRVSSD
.... . ... :. .. . .: : : :: : : :: ... :. . :
XP_006 ISQRIYKEEREYFDE-MKEYGPIHILWSASEEDLV--DTLKDVASCIDRCCKATEKRMSG
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB8 EDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQEC
. : ... :.: : .. :: . . ... ..: :. :. : . .
XP_006 LSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL---TYKKADTDLLPEEIGKL
270 280 290 300 310
350 360 370 380 390 400
pF1KB8 CQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
.: : ... : . .:.. .. . .:.: .:.. .. .. .:
XP_006 EDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHL
320 330 340 350 360 370
XP_006 EEASEDKP
380
>>XP_016856915 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa)
initn: 213 init1: 95 opt: 179 Z-score: 184.8 bits: 43.0 E(85289): 0.0015
Smith-Waterman score: 219; 21.5% identity (53.5% similar) in 391 aa overlap (9-396:20-369)
10 20 30 40
pF1KB8 MAAVPELLQQQEEDRSKLRSVSVDLNVDPSLQIDIPDALSERDKVKFTV
: . ::. :... . .. .: .. ... . . .
XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVD-EPESHVTTIETF-----ITYRI
10 20 30 40 50
50 60 70 80 90 100
pF1KB8 HTKTTLPTFQSPEFSVTRQHEDFVWLHDTLIETTDYAGLIIPPAPTKPDFDGPREKMQKL
:::. :.: :: : :...::.::. : :. . ::::: : : : :..
XP_016 ITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMVERF---
60 70 80 90 100
110 120 130 140 150 160
pF1KB8 GEGEGSMTKEEFAKMKQELEAEYLAVFKKTVSSHEVFLQRLSSHPVLSKDRNFHVFLEYD
...: .:.. :. : ::.:...::.:. ...:..:: .
XP_016 --------NDDF------IETRRKALHK--------FLNRIADHPTLTFNEDFKIFLTAQ
110 120 130 140
170 180 190 200 210 220
pF1KB8 Q-DLSVRRKNTKEMFGGFFKSVVKSADEVLFTGVKEVDDFFEQEKNFLINYYNRIKDSCV
.:: ..:. ... . ..: :. . :::. . : . .::. . ..:.
XP_016 AWELSSHKKQGPGLLSRMGQTVRAVASSM--RGVKNRPEEFMEMNNFIELFSQKINLIDK
150 160 170 180 190 200
230 240 250 260 270 280
pF1KB8 KADKMTRSHKNVADDYIHTAACLHSL--ALEEPTVIKKYLLKVAELFEKLRKVEGRVSSD
.... . ... :. .. . .: : : :: : : :: ... :. . :
XP_016 ISQRIYKEEREYFDE-MKEYGPIHILWSASEEDLV--DTLKDVASCIDRCCKATEKRMSG
210 220 230 240 250 260
290 300 310 320 330 340
pF1KB8 EDLKLTELLRYYMLNIEAAKDLLYRRTKALIDYENSNKALDKARLKSKDVKLAEAHQQEC
. : ... :.: : .. :: . . ... ..: :. :. : . .
XP_016 LSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVEVL---TYKKADTDLLPEEIGKL
270 280 290 300 310
350 360 370 380 390 400
pF1KB8 CQKFEQLSESAKEELINFKRKRVAAFRKNLIEMSELEIKHARNNVSLLQSCIDLFKNN
.: : ... : . .:.. .. . .:.: .:.. .. .. .:
XP_016 EDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHL
320 330 340 350 360 370
XP_016 EEASEDKP
380
404 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 10:04:30 2016 done: Fri Nov 4 10:04:31 2016
Total Scan time: 5.100 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]