Result of FASTA (omim) for
pFN21AB8133
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8133, 566 aa
1>>>pF1KB8133 566 - 566 aa - 566 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8847+/-0.000395; mu= 16.0902+/- 0.025
mean_var=110.9702+/-23.677, 0's: 0 Z-trim(113.6): 90 B-trim: 78 in 1/55
Lambda= 0.121751
statistics sampled from 22996 (23085) to 22996 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.646), E-opt: 0.2 (0.271), width: 16
Scan time: 8.320
The best scores are: opt bits E(85289)
NP_061871 (OMIM: 609072) F-box/WD repeat-containin ( 566) 3849 687.7 2.6e-197
XP_005266146 (OMIM: 609072) PREDICTED: F-box/WD re ( 576) 3029 543.7 6e-154
XP_016870301 (OMIM: 609072) PREDICTED: F-box/WD re ( 548) 2366 427.2 6.6e-119
XP_011517091 (OMIM: 609072) PREDICTED: F-box/WD re ( 558) 1546 283.2 1.5e-75
>>NP_061871 (OMIM: 609072) F-box/WD repeat-containing pr (566 aa)
initn: 3849 init1: 3849 opt: 3849 Z-score: 3663.3 bits: 687.7 E(85289): 2.6e-197
Smith-Waterman score: 3849; 99.8% identity (100.0% similar) in 566 aa overlap (1-566:1-566)
10 20 30 40 50 60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB8 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB8 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB8 RDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
NP_061 RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
490 500 510 520 530 540
550 560
pF1KB8 PRTMRVLQAPRPRPRTFFSWLASQRR
::::::::::::::::::::::::::
NP_061 PRTMRVLQAPRPRPRTFFSWLASQRR
550 560
>>XP_005266146 (OMIM: 609072) PREDICTED: F-box/WD repeat (576 aa)
initn: 3029 init1: 3029 opt: 3029 Z-score: 2884.8 bits: 543.7 E(85289): 6e-154
Smith-Waterman score: 3819; 98.1% identity (98.3% similar) in 576 aa overlap (1-566:1-576)
10 20 30 40 50 60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVK---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKAIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 -------IWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TAAPAEQIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKY
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB8 LIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB8 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB8 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTAS
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_005 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTAS
490 500 510 520 530 540
540 550 560
pF1KB8 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
::::::::::::::::::::::::::::::::::::
XP_005 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
550 560 570
>>XP_016870301 (OMIM: 609072) PREDICTED: F-box/WD repeat (548 aa)
initn: 3709 init1: 2350 opt: 2366 Z-score: 2255.7 bits: 427.2 E(85289): 6.6e-119
Smith-Waterman score: 3677; 96.6% identity (96.8% similar) in 566 aa overlap (1-566:1-548)
10 20 30 40 50 60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKIWS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEIAVISLDSFAL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB8 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESENVNVVKRLFK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB8 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVVAGPAPAHAKE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB8 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKYLIFTTGCLTY
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKS------------
310 320 330 340
370 380 390 400 410 420
pF1KB8 SPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ------IKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGLSPDNRYLYVN
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB8 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPNDECFFIFLDVS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB8 RDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::::
XP_016 RDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTASDDATIKAWRS
470 480 490 500 510 520
550 560
pF1KB8 PRTMRVLQAPRPRPRTFFSWLASQRR
::::::::::::::::::::::::::
XP_016 PRTMRVLQAPRPRPRTFFSWLASQRR
530 540
>>XP_011517091 (OMIM: 609072) PREDICTED: F-box/WD repeat (558 aa)
initn: 2889 init1: 1530 opt: 1546 Z-score: 1477.2 bits: 283.2 E(85289): 1.5e-75
Smith-Waterman score: 3647; 95.0% identity (95.1% similar) in 576 aa overlap (1-566:1-558)
10 20 30 40 50 60
pF1KB8 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDEGGTPLLPDSLVYQIFLSLGPADVLAAGLVCRQWQAVSRDEFLWREQFYRYYQVARDV
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVK---
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRHPAAMSWYEEFQRLYDTVPCVEVQTLREHTDQVLHLSFSHSGYQFASCSKDCTVKAIT
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB8 -------IWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TAAPAEQIWSNDLTISLLHSADMRPYNWSYTQFSQFNKDDSLLLASGVFLGPHNSSSGEI
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB8 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVISLDSFALLSRVRNKPYDVFGCWLTETSLISGNLHRIGDITSCSVLWLNNAFQDVESE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB8 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NVNVVKRLFKIQNLNASTVRTVMVADCSRFDSPDLLLEAGDPATSPCRIFDLGSDNEEVV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB8 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKSKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGPAPAHAKEGLRHFLDRVLEGRAQPQLSERMLETKVAELLAQGHTKPPERSATGAKS--
310 320 330 340 350
360 370 380 390 400 410
pF1KB8 LIFTTGCLTYSPHQIGIKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
::::::::::::::::::::::::::::::::::::::::::::
XP_011 ----------------IKQILPHQMTTAGPVLGEGRGSDAFFDALDHVIDIHGHIIGMGL
360 370 380 390 400
420 430 440 450 460 470
pF1KB8 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPDNRYLYVNSRAWPNGAVVADPMQPPPIAEEIDLLVFDLKTMREVRRALRAHRAYTPND
410 420 430 440 450 460
480 490 500 510 520 530
pF1KB8 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLQHEDVVNSVVFSPQEQELLLTAS
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_011 ECFFIFLDVSRDFVASGAEDRHGYIWDRHYNICLARLRHEDVVNSVVFSPQEQELLLTAS
470 480 490 500 510 520
540 550 560
pF1KB8 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
::::::::::::::::::::::::::::::::::::
XP_011 DDATIKAWRSPRTMRVLQAPRPRPRTFFSWLASQRR
530 540 550
566 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:51:06 2016 done: Fri Nov 4 09:51:07 2016
Total Scan time: 8.320 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]