Result of FASTA (omim) for
pFN21AB8122
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8122, 214 aa
1>>>pF1KB8122 214 - 214 aa - 214 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.0466+/-0.000351; mu= -2.1529+/- 0.022
mean_var=236.6351+/-46.782, 0's: 0 Z-trim(121.9): 20 B-trim: 320 in 1/55
Lambda= 0.083375
statistics sampled from 39073 (39093) to 39073 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.458), width: 16
Scan time: 5.830
The best scores are: opt bits E(85289)
NP_877724 (OMIM: 608073) nucleoplasmin-2 isoform 1 ( 214) 1380 177.9 1.1e-44
XP_016868438 (OMIM: 608073) PREDICTED: nucleoplasm ( 214) 1380 177.9 1.1e-44
XP_011542664 (OMIM: 608073) PREDICTED: nucleoplasm ( 214) 1380 177.9 1.1e-44
XP_016868437 (OMIM: 608073) PREDICTED: nucleoplasm ( 214) 1380 177.9 1.1e-44
NP_001273609 (OMIM: 608073) nucleoplasmin-2 isofor ( 214) 1380 177.9 1.1e-44
XP_011542665 (OMIM: 608073) PREDICTED: nucleoplasm ( 214) 1380 177.9 1.1e-44
XP_011542662 (OMIM: 608073) PREDICTED: nucleoplasm ( 289) 1268 164.5 1.6e-40
XP_011542666 (OMIM: 608073) PREDICTED: nucleoplasm ( 156) 994 131.3 8.4e-31
NP_001273610 (OMIM: 608073) nucleoplasmin-2 isofor ( 136) 804 108.4 5.8e-24
XP_016868439 (OMIM: 608073) PREDICTED: nucleoplasm ( 172) 789 106.7 2.4e-23
XP_016868436 (OMIM: 608073) PREDICTED: nucleoplasm ( 247) 789 106.8 3.2e-23
NP_008924 (OMIM: 606456) nucleoplasmin-3 [Homo sap ( 178) 304 48.4 9e-06
XP_005265977 (OMIM: 164040) PREDICTED: nucleophosm ( 230) 257 42.8 0.00055
NP_954654 (OMIM: 164040) nucleophosmin isoform 2 [ ( 265) 257 42.8 0.00061
NP_001032827 (OMIM: 164040) nucleophosmin isoform ( 259) 255 42.6 0.00071
NP_002511 (OMIM: 164040) nucleophosmin isoform 1 [ ( 294) 255 42.6 0.00078
>>NP_877724 (OMIM: 608073) nucleoplasmin-2 isoform 1 [Ho (214 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 923.0 bits: 177.9 E(85289): 1.1e-44
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_877 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
130 140 150 160 170 180
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
NP_877 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
190 200 210
>>XP_016868438 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (214 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 923.0 bits: 177.9 E(85289): 1.1e-44
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
130 140 150 160 170 180
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
XP_016 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
190 200 210
>>XP_011542664 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (214 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 923.0 bits: 177.9 E(85289): 1.1e-44
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
130 140 150 160 170 180
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
XP_011 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
190 200 210
>>XP_016868437 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (214 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 923.0 bits: 177.9 E(85289): 1.1e-44
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
130 140 150 160 170 180
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
XP_016 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
190 200 210
>>NP_001273609 (OMIM: 608073) nucleoplasmin-2 isoform 1 (214 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 923.0 bits: 177.9 E(85289): 1.1e-44
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
130 140 150 160 170 180
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
NP_001 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
190 200 210
>>XP_011542665 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (214 aa)
initn: 1380 init1: 1380 opt: 1380 Z-score: 923.0 bits: 177.9 E(85289): 1.1e-44
Smith-Waterman score: 1380; 100.0% identity (100.0% similar) in 214 aa overlap (1-214:1-214)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
130 140 150 160 170 180
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
XP_011 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
190 200 210
>>XP_011542662 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (289 aa)
initn: 1268 init1: 1268 opt: 1268 Z-score: 848.4 bits: 164.5 E(85289): 1.6e-40
Smith-Waterman score: 1268; 100.0% identity (100.0% similar) in 195 aa overlap (20-214:95-289)
10 20 30 40
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTI
::::::::::::::::::::::::::::::
XP_011 PPGSPPHPTCPLRLSAGDLTVLETGLARSHGCELSQERRTWTFRPQLEGKQSCRLLLHTI
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB8 CLGEKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLGEKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAG
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB8 SGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVP
190 200 210 220 230 240
170 180 190 200 210
pF1KB8 QKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 QKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
250 260 270 280
>>XP_011542666 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (156 aa)
initn: 994 init1: 994 opt: 994 Z-score: 674.0 bits: 131.3 E(85289): 8.4e-31
Smith-Waterman score: 994; 100.0% identity (100.0% similar) in 156 aa overlap (59-214:1-156)
30 40 50 60 70 80
pF1KB8 TWTFRPQLEGKQSCRLLLHTICLGEKAKEEMHRVEILPPANQEDKKMQPVTIASLQASVL
::::::::::::::::::::::::::::::
XP_011 MHRVEILPPANQEDKKMQPVTIASLQASVL
10 20 30
90 100 110 120 130 140
pF1KB8 PMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMVSMVGVQLSPPVTFQLRAGSGPVFLSGQERYEASDLTWEEEEEEEGEEEEEEEEDDED
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB8 EDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDADISLEEQSPVKQVKRLVPQKQASVAKKKKLEKEEEEIRASVRDKSPVKKAKATARAK
100 110 120 130 140 150
210
pF1KB8 KPGFKK
::::::
XP_011 KPGFKK
>>NP_001273610 (OMIM: 608073) nucleoplasmin-2 isoform 2 (136 aa)
initn: 804 init1: 804 opt: 804 Z-score: 551.2 bits: 108.4 E(85289): 5.8e-24
Smith-Waterman score: 804; 100.0% identity (100.0% similar) in 122 aa overlap (1-122:1-122)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::
NP_001 YEKKAGKRRRGNKSQR
130
>>XP_016868439 (OMIM: 608073) PREDICTED: nucleoplasmin-2 (172 aa)
initn: 789 init1: 789 opt: 789 Z-score: 540.1 bits: 106.7 E(85289): 2.4e-23
Smith-Waterman score: 1012; 80.4% identity (80.4% similar) in 214 aa overlap (1-214:1-172)
10 20 30 40 50 60
pF1KB8 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHTICLGEKAKEEMH
::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNLSSASSTEEKAVTTVLWGCELSQERRTWTFRPQLEGKQSCRLLLHT------------
10 20 30 40
70 80 90 100 110 120
pF1KB8 RVEILPPANQEDKKMQPVTIASLQASVLPMVSMVGVQLSPPVTFQLRAGSGPVFLSGQER
::::::::::::::::::::::::::::::
XP_016 ------------------------------VSMVGVQLSPPVTFQLRAGSGPVFLSGQER
50 60 70
130 140 150 160 170 180
pF1KB8 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEASDLTWEEEEEEEGEEEEEEEEDDEDEDADISLEEQSPVKQVKRLVPQKQASVAKKKK
80 90 100 110 120 130
190 200 210
pF1KB8 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
::::::::::::::::::::::::::::::::::
XP_016 LEKEEEEIRASVRDKSPVKKAKATARAKKPGFKK
140 150 160 170
214 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:43:59 2016 done: Fri Nov 4 09:44:00 2016
Total Scan time: 5.830 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]