Result of FASTA (omim) for
pFN21AB8105
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB8105, 117 aa
1>>>pF1KB8105 117 - 117 aa - 117 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8095+/-0.000294; mu= 12.7491+/- 0.018
mean_var=53.9627+/-10.815, 0's: 0 Z-trim(117.2): 18 B-trim: 5 in 1/55
Lambda= 0.174593
statistics sampled from 28968 (28986) to 28968 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.34), width: 16
Scan time: 3.510
The best scores are: opt bits E(85289)
NP_113600 (OMIM: 607420) gamma-aminobutyric acid r ( 117) 793 206.9 6.1e-54
NP_009209 (OMIM: 605125) gamma-aminobutyric acid r ( 117) 698 183.0 9.8e-47
XP_005253401 (OMIM: 607420) PREDICTED: gamma-amino ( 146) 650 170.9 5.1e-43
NP_009216 (OMIM: 607452) gamma-aminobutyric acid r ( 117) 479 127.8 3.9e-30
NP_001004343 (OMIM: 609605) microtubule-associated ( 147) 309 85.0 3.7e-17
XP_005273196 (OMIM: 609605) PREDICTED: microtubule ( 147) 309 85.0 3.7e-17
NP_115903 (OMIM: 601242) microtubule-associated pr ( 121) 270 75.2 2.8e-14
XP_011527387 (OMIM: 601242) PREDICTED: microtubule ( 182) 270 75.3 4e-14
XP_011527385 (OMIM: 601242) PREDICTED: microtubule ( 223) 270 75.3 4.8e-14
XP_011527386 (OMIM: 601242) PREDICTED: microtubule ( 223) 270 75.3 4.8e-14
NP_852610 (OMIM: 601242) microtubule-associated pr ( 125) 257 71.9 2.8e-13
NP_073729 (OMIM: 609604) microtubule-associated pr ( 125) 255 71.4 4e-13
>>NP_113600 (OMIM: 607420) gamma-aminobutyric acid recep (117 aa)
initn: 793 init1: 793 opt: 793 Z-score: 1089.4 bits: 206.9 E(85289): 6.1e-54
Smith-Waterman score: 793; 100.0% identity (100.0% similar) in 117 aa overlap (1-117:1-117)
10 20 30 40 50 60
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_113 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
70 80 90 100 110
>>NP_009209 (OMIM: 605125) gamma-aminobutyric acid recep (117 aa)
initn: 698 init1: 698 opt: 698 Z-score: 960.1 bits: 183.0 E(85289): 9.8e-47
Smith-Waterman score: 698; 87.1% identity (96.6% similar) in 116 aa overlap (1-116:1-116)
10 20 30 40 50 60
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
::: :::.:::: :..::::::::::::::::::::::::. ::::.:::::::::::::
NP_009 MKFVYKEEHPFEKRRSEGEKIRKKYPDRVPVIVEKAPKARIGDLDKKKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
::::::::::: ::::::::::.::::::::::::...::::.:::.:::::::::
NP_009 YFLIRKRIHLRAEDALFFFVNNVIPPTSATMGQLYQEHHEEDFFLYIAYSDESVYGL
70 80 90 100 110
>>XP_005253401 (OMIM: 607420) PREDICTED: gamma-aminobuty (146 aa)
initn: 650 init1: 650 opt: 650 Z-score: 893.3 bits: 170.9 E(85289): 5.1e-43
Smith-Waterman score: 650; 100.0% identity (100.0% similar) in 96 aa overlap (1-96:1-96)
10 20 30 40 50 60
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
::::::::::::::::::::::::::::::::::::
XP_005 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEVMVLVAQYWMPSSAVWHPLALVLD
70 80 90 100 110 120
XP_005 ALITHLRSGAEGVIYPDPLTYGSVRL
130 140
>>NP_009216 (OMIM: 607452) gamma-aminobutyric acid recep (117 aa)
initn: 514 init1: 479 opt: 479 Z-score: 661.9 bits: 127.8 E(85289): 3.9e-30
Smith-Waterman score: 479; 61.2% identity (86.2% similar) in 116 aa overlap (1-116:1-116)
10 20 30 40 50 60
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKARVPDLDKRKYLVPSDLTVGQF
::...:::: .:.: :. ::: ::::::::::::. ... :.::::::::::.::.::
NP_009 MKWMFKEDHSLEHRCVESAKIRAKYPDRVPVIVEKVSGSQIVDIDKRKYLVPSDITVAQF
10 20 30 40 50 60
70 80 90 100 110
pF1KB8 YFLIRKRIHLRPEDALFFFVNNTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYGK
...:::::.: : :.:.::..:.: .: ::::::: ...:: ::::::: :...:
NP_009 MWIIRKRIQLPSEKAIFLFVDKTVPQSSLTMGQLYEKEKDEDGFLYVAYSGENTFGF
70 80 90 100 110
>>NP_001004343 (OMIM: 609605) microtubule-associated pro (147 aa)
initn: 308 init1: 142 opt: 309 Z-score: 429.0 bits: 85.0 E(85289): 3.7e-17
Smith-Waterman score: 309; 39.5% identity (76.3% similar) in 114 aa overlap (5-116:13-126)
10 20 30 40 50
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKAR-VPDLDKRKYLV
.:. . . :..: :: :.:...::.::. :. .: ::: :.::
NP_001 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 PSDLTVGQFYFLIRKRIHLRPEDALFFFVNN-TIPPTSATMGQLYEDNHEEDYFLYVAYS
:..::. :: .::.:. :: .:....::: .. ::::...:.: ..:: :.:..:.
NP_001 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
pF1KB8 DESVYGK
.. ..:
NP_001 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>XP_005273196 (OMIM: 609605) PREDICTED: microtubule-ass (147 aa)
initn: 308 init1: 142 opt: 309 Z-score: 429.0 bits: 85.0 E(85289): 3.7e-17
Smith-Waterman score: 309; 39.5% identity (76.3% similar) in 114 aa overlap (5-116:13-126)
10 20 30 40 50
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAPKAR-VPDLDKRKYLV
.:. . . :..: :: :.:...::.::. :. .: ::: :.::
XP_005 MPPPQKIPSVRPFKQRKSLAIRQEEVAGIRAKFPNKIPVVVERYPRETFLPPLDKTKFLV
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 PSDLTVGQFYFLIRKRIHLRPEDALFFFVNN-TIPPTSATMGQLYEDNHEEDYFLYVAYS
:..::. :: .::.:. :: .:....::: .. ::::...:.: ..:: :.:..:.
XP_005 PQELTMTQFLSIIRSRMVLRATEAFYLLVNNKSLVSMSATMAEIYRDYKDEDGFVYMTYA
70 80 90 100 110 120
pF1KB8 DESVYGK
.. ..:
XP_005 SQETFGCLESAAPRDGSSLEDRPCNPL
130 140
>>NP_115903 (OMIM: 601242) microtubule-associated protei (121 aa)
initn: 260 init1: 123 opt: 270 Z-score: 377.2 bits: 75.2 E(85289): 2.8e-14
Smith-Waterman score: 270; 34.2% identity (78.9% similar) in 114 aa overlap (5-116:7-120)
10 20 30 40 50
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVEKAP-KARVPDLDKRKYLVPSDLTV
.:. . : : :: ..:: ..:...:::.:. . ..: ::: :.:::. ...
NP_115 MPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIERYKGEKQLPVLDKTKFLVPDHVNM
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB8 GQFYFLIRKRIHLRPEDALFFFVN-NTIPPTSATMGQLYEDNHEEDYFLYVAYSDESVYG
... .::.:..: : .:.:..:: ... .:. ....::....:: :::..:... ..:
NP_115 SELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIADIYEQEKDEDGFLYMVYASQETFG
70 80 90 100 110 120
pF1KB8 K
NP_115 F
>>XP_011527387 (OMIM: 601242) PREDICTED: microtubule-ass (182 aa)
initn: 260 init1: 123 opt: 270 Z-score: 374.5 bits: 75.3 E(85289): 4e-14
Smith-Waterman score: 270; 34.2% identity (78.9% similar) in 114 aa overlap (5-116:68-181)
10 20 30
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVE
.:. . : : :: ..:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB8 KAP-KARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVN-NTIPPTSATMG
. . ..: ::: :.:::. ...... .::.:..: : .:.:..:: ... .:. ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
100 110 120 130 140 150
100 110
pF1KB8 QLYEDNHEEDYFLYVAYSDESVYGK
..::....:: :::..:... ..:
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
160 170 180
>>XP_011527385 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 260 init1: 123 opt: 270 Z-score: 373.2 bits: 75.3 E(85289): 4.8e-14
Smith-Waterman score: 270; 34.2% identity (78.9% similar) in 114 aa overlap (5-116:109-222)
10 20 30
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVE
.:. . : : :: ..:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 KAP-KARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVN-NTIPPTSATMG
. . ..: ::: :.:::. ...... .::.:..: : .:.:..:: ... .:. ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
140 150 160 170 180 190
100 110
pF1KB8 QLYEDNHEEDYFLYVAYSDESVYGK
..::....:: :::..:... ..:
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
200 210 220
>>XP_011527386 (OMIM: 601242) PREDICTED: microtubule-ass (223 aa)
initn: 260 init1: 123 opt: 270 Z-score: 373.2 bits: 75.3 E(85289): 4.8e-14
Smith-Waterman score: 270; 34.2% identity (78.9% similar) in 114 aa overlap (5-116:109-222)
10 20 30
pF1KB8 MKFQYKEDHPFEYRKKEGEKIRKKYPDRVPVIVE
.:. . : : :: ..:: ..:...:::.:
XP_011 RSPQTADTSPRPRAPACAPSRARAMPSDRPFKQRRSFADRCKEVQQIRDQHPSKIPVIIE
80 90 100 110 120 130
40 50 60 70 80 90
pF1KB8 KAP-KARVPDLDKRKYLVPSDLTVGQFYFLIRKRIHLRPEDALFFFVN-NTIPPTSATMG
. . ..: ::: :.:::. ...... .::.:..: : .:.:..:: ... .:. ..
XP_011 RYKGEKQLPVLDKTKFLVPDHVNMSELVKIIRRRLQLNPTQAFFLLVNQHSMVSVSTPIA
140 150 160 170 180 190
100 110
pF1KB8 QLYEDNHEEDYFLYVAYSDESVYGK
..::....:: :::..:... ..:
XP_011 DIYEQEKDEDGFLYMVYASQETFGF
200 210 220
117 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 09:31:09 2016 done: Fri Nov 4 09:31:10 2016
Total Scan time: 3.510 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]