Result of FASTA (omim) for
pFN21AB7247
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7247, 596 aa
1>>>pF1KB7247 596 - 596 aa - 596 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3926+/-0.000403; mu= 18.9491+/- 0.025
mean_var=77.6791+/-16.190, 0's: 0 Z-trim(111.8): 24 B-trim: 0 in 0/54
Lambda= 0.145520
statistics sampled from 20442 (20462) to 20442 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.588), E-opt: 0.2 (0.24), width: 16
Scan time: 10.260
The best scores are: opt bits E(85289)
NP_839947 (OMIM: 607828) otopetrin-3 isoform 1 [Ho ( 596) 3998 849.5 0
XP_011523046 (OMIM: 607828) PREDICTED: otopetrin-3 ( 567) 3773 802.2 0
NP_001258934 (OMIM: 607828) otopetrin-3 isoform 2 ( 578) 3771 801.8 0
XP_011523781 (OMIM: 607827) PREDICTED: otopetrin-2 ( 562) 556 126.8 1.9e-28
NP_835454 (OMIM: 607827) otopetrin-2 [Homo sapiens ( 562) 556 126.8 1.9e-28
NP_819056 (OMIM: 607806) otopetrin-1 [Homo sapiens ( 612) 297 72.5 4.7e-12
>>NP_839947 (OMIM: 607828) otopetrin-3 isoform 1 [Homo s (596 aa)
initn: 3998 init1: 3998 opt: 3998 Z-score: 4536.7 bits: 849.5 E(85289): 0
Smith-Waterman score: 3998; 100.0% identity (100.0% similar) in 596 aa overlap (1-596:1-596)
10 20 30 40 50 60
pF1KB7 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 TRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 LLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 LLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEY
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 CLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 CLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQI
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 EASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 EASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB7 GAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 GAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWET
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB7 VPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 VPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNIT
490 500 510 520 530 540
550 560 570 580 590
pF1KB7 LWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_839 LWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
550 560 570 580 590
>>XP_011523046 (OMIM: 607828) PREDICTED: otopetrin-3 iso (567 aa)
initn: 3770 init1: 3770 opt: 3773 Z-score: 4281.7 bits: 802.2 E(85289): 0
Smith-Waterman score: 3773; 99.6% identity (99.8% similar) in 565 aa overlap (32-596:4-567)
10 20 30 40 50 60
pF1KB7 GRGARAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAAT
:: .::::::::::::::::::::::::::
XP_011 MPLPA-SEAQETEAAPEKENRVDVGAEERAAAT
10 20 30
70 80 90 100 110 120
pF1KB7 RPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKVAVTLGDV
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 WILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFRV
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 GYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNLL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 LWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLYPFSTEYC
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 LICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCVFVLFQIE
280 290 300 310 320 330
370 380 390 400 410 420
pF1KB7 ASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSLDVVLLMG
340 350 360 370 380 390
430 440 450 460 470 480
pF1KB7 AALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHRRPLWETV
400 410 420 430 440 450
490 500 510 520 530 540
pF1KB7 PEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITL
460 470 480 490 500 510
550 560 570 580 590
pF1KB7 WMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
520 530 540 550 560
>>NP_001258934 (OMIM: 607828) otopetrin-3 isoform 2 [Hom (578 aa)
initn: 3770 init1: 3770 opt: 3771 Z-score: 4279.3 bits: 801.8 E(85289): 0
Smith-Waterman score: 3771; 98.6% identity (98.8% similar) in 573 aa overlap (30-596:6-578)
10 20 30 40 50
pF1KB7 MGRGARAAAAQSRWGRASRASVSPGRTIRSAPA------VGEAQETEAAPEKENRVDVGA
:::: .:::::::::::::::::::
NP_001 MPLPASAPAEATPMPSSEAQETEAAPEKENRVDVGA
10 20 30
60 70 80 90 100 110
pF1KB7 EERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNKV
40 50 60 70 80 90
120 130 140 150 160 170
pF1KB7 AVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTF
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB7 CLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLML
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB7 TLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLATNLLLWVLAVTNDSMHREIEAELGILMEKSTGNETNTCLCLNATACEAFRRGFLMLY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB7 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV
280 290 300 310 320 330
360 370 380 390 400 410
pF1KB7 FVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVLFQIEASGPAIACQYFTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRSL
340 350 360 370 380 390
420 430 440 450 460 470
pF1KB7 DVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLHR
400 410 420 430 440 450
480 490 500 510 520 530
pF1KB7 RPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPLWETVPEGLAGKQEAEPPRRGSLLELGQGLQRASLAYIHSYSHLNWKRRALKEISLFL
460 470 480 490 500 510
540 550 560 570 580 590
pF1KB7 ILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILCNITLWMMPAFGIHPEFENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYL
520 530 540 550 560 570
pF1KB7 GA
::
NP_001 GA
>>XP_011523781 (OMIM: 607827) PREDICTED: otopetrin-2 iso (562 aa)
initn: 1445 init1: 556 opt: 556 Z-score: 631.7 bits: 126.8 E(85289): 1.9e-28
Smith-Waterman score: 1455; 43.0% identity (71.9% similar) in 540 aa overlap (84-594:25-560)
60 70 80 90 100 110
pF1KB7 AEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNK
.:.:.:.: :::.::..:. ..: . :::
XP_011 MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNK
10 20 30 40 50
120 130 140 150 160 170
pF1KB7 VAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCT
::: ::. ::... .:. ::.:.:. :.: : :: :.: ::::.:.::.::::: ::
XP_011 VAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICT
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB7 FCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLM
. ...:..:: : ..:.: . .. .:. ::. .::. :: ::::.:. ..: ::::
XP_011 LIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLM
120 130 140 150 160 170
240 250 260 270 280
pF1KB7 LTLATNLLLWVLAVTNDSMHRE--------IEAELGILMEKSTGNET--NTCLCLNATAC
.::.::: .:. ::...:.:. .. .. .. . : . ..::: .:. :
XP_011 FTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAV-C
180 190 200 210 220 230
290 300 310 320 330 340
pF1KB7 EAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIF--GP
. :..:...::::. :: :. ..:.:::::::: .: : . .: : : ::
XP_011 QIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGP
240 250 260 270 280 290
350 360 370 380 390 400
pF1KB7 LLGLLVLLAGVCVFVLFQIEASGPAIAC-QYFTLYYAFYVAVLPTMSLACLAGTAIHGLE
.::::....:. ::.......:: . : ...::.: .. : .:. :.:. :. ..
XP_011 VLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFD
300 310 320 330 340 350
410 420 430 440 450 460
pF1KB7 ERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQ
.: .: :::::.:::.:::::::::..:.:.::::.:: :..:: : :...::.: :
XP_011 RRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQ
360 370 380 390 400 410
470 480 490 500
pF1KB7 HIAQNLFIIEGLHRRPLWETVPEGLAGKQE----------------AEPPRRGSLLELGQ
: ::.::::.::: : :.. :. : :: : :. .
XP_011 HTFQNMFIIESLHRGPPGAE-PHSTHPKEPCQDLTFTNLDALHTLSACPPNPG-LVSPSP
420 430 440 450 460 470
510 520 530 540 550 560
pF1KB7 GLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGY
. :: ..: . : . .:.:. ::.:::::.:::. ::.::::: .:.: : .: :::::
XP_011 SDQREAVAIV-STPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGY
480 490 500 510 520 530
570 580 590
pF1KB7 QIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
..: .:::. ::.:.:::::.:..:.:::.
XP_011 SLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS
540 550 560
>>NP_835454 (OMIM: 607827) otopetrin-2 [Homo sapiens] (562 aa)
initn: 1445 init1: 556 opt: 556 Z-score: 631.7 bits: 126.8 E(85289): 1.9e-28
Smith-Waterman score: 1455; 43.0% identity (71.9% similar) in 540 aa overlap (84-594:25-560)
60 70 80 90 100 110
pF1KB7 AEERAAATRPRQKSWLVRHFSLLLRRDRQAQKAGQLFSGLLALNVVFLGGAFICSMIFNK
.:.:.:.: :::.::..:. ..: . :::
NP_835 MSEELAQGPKESPPAPRAGPREVWKKGGRLLSVLLAVNVLLLACTLISGGAFNK
10 20 30 40 50
120 130 140 150 160 170
pF1KB7 VAVTLGDVWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCT
::: ::. ::... .:. ::.:.:. :.: : :: :.: ::::.:.::.::::: ::
NP_835 VAVYDTDVFALLTAMMLLATLWILFYLLRTVRCPCAVPYRDAHAGPIWLRGGLVLFGICT
60 70 80 90 100 110
180 190 200 210 220 230
pF1KB7 FCLNIFRVGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLM
. ...:..:: : ..:.: . .. .:. ::. .::. :: ::::.:. ..: ::::
NP_835 LIMDVFKTGYYSSFFECQSAIKILHPLIQAVFVIIQTYFLWVSAKDCVHVHLDLTWCGLM
120 130 140 150 160 170
240 250 260 270 280
pF1KB7 LTLATNLLLWVLAVTNDSMHRE--------IEAELGILMEKSTGNET--NTCLCLNATAC
.::.::: .:. ::...:.:. .. .. .. . : . ..::: .:. :
NP_835 FTLTTNLAIWMAAVVDESVHQSHSYSSSHSNASHARLISDQHADNPVGGDSCLCSTAV-C
180 190 200 210 220 230
290 300 310 320 330 340
pF1KB7 EAFRRGFLMLYPFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIF--GP
. :..:...::::. :: :. ..:.:::::::: .: : . .: : : ::
NP_835 QIFQQGYFYLYPFNIEYSLFASTMLYVMWKNVGRFLASTPGHSHTPTPVSLFRETFFAGP
240 250 260 270 280 290
350 360 370 380 390 400
pF1KB7 LLGLLVLLAGVCVFVLFQIEASGPAIAC-QYFTLYYAFYVAVLPTMSLACLAGTAIHGLE
.::::....:. ::.......:: . : ...::.: .. : .:. :.:. :. ..
NP_835 VLGLLLFVVGLAVFIIYEVQVSGDGSRTRQALVIYYSFNIVCLGLTTLVSLSGSIIYRFD
300 310 320 330 340 350
410 420 430 440 450 460
pF1KB7 ERELDTVKNPTRSLDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQ
.: .: :::::.:::.:::::::::..:.:.::::.:: :..:: : :...::.: :
NP_835 RRAMDHHKNPTRTLDVALLMGAALGQYAISYYSIVAVVAGTPQDLLAGLNLTHALLMIAQ
360 370 380 390 400 410
470 480 490 500
pF1KB7 HIAQNLFIIEGLHRRPLWETVPEGLAGKQE----------------AEPPRRGSLLELGQ
: ::.::::.::: : :.. :. : :: : :. .
NP_835 HTFQNMFIIESLHRGPPGAE-PHSTHPKEPCQDLTFTNLDALHTLSACPPNPG-LVSPSP
420 430 440 450 460 470
510 520 530 540 550 560
pF1KB7 GLQRASLAYIHSYSHLNWKRRALKEISLFLILCNITLWMMPAFGIHPEFENGLEKDFYGY
. :: ..: . : . .:.:. ::.:::::.:::. ::.::::: .:.: : .: :::::
NP_835 SDQREAVAIV-STPRSQWRRQCLKDISLFLLLCNVILWIMPAFGARPHFSNTVEVDFYGY
480 490 500 510 520 530
570 580 590
pF1KB7 QIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
..: .:::. ::.:.:::::.:..:.:::.
NP_835 SLWAVIVNICLPFGIFYRMHAVSSLLEVYVLS
540 550 560
>>NP_819056 (OMIM: 607806) otopetrin-1 [Homo sapiens] (612 aa)
initn: 926 init1: 297 opt: 297 Z-score: 337.3 bits: 72.5 E(85289): 4.7e-12
Smith-Waterman score: 960; 32.1% identity (59.9% similar) in 611 aa overlap (36-593:3-609)
10 20 30 40 50 60
pF1KB7 RAAAAQSRWGRASRASVSPGRTIRSAPAVGEAQETEAAPEKENRVDVGAEERAAATRPRQ
:. . :.:. ..:.. :: : .
NP_819 MLEGLGSPASPRAAASASVAGSSGPAACSPPS
10 20 30
70 80 90 100 110 120
pF1KB7 KSWLVRHFSLLLRRD--RQA--QKAGQLFSGLLALNVVFLGGAFIC-SMIFNKVAVTLGD
.: : :: : . :: ....:. .: .::..: .. . . ..:. .:
NP_819 SSAPRSPESPAPRRGGVRASVPQKLAEMLSSQYGL-IVFVAGLLLLLAWAVHAAGVSKSD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 VWILLATLKVLSLLWLLYYVASTTRRPHAVLYQDPHAGPLWVRGSLVLFGSCTFCLNIFR
. .:..: .:.:::.:.::. .. . . .: ::: :.:::..::. : :. ..
NP_819 LLCFLTALMLLQLLWMLWYVGRSSAHRRLFRLKDTHAGAGWLRGSITLFAVITVILGCLK
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 VGYDVSHIRCKSQLDLVFSVIEMVFIGVQTWVLWKHCKDCVRVQTNFTRCGLMLTLATNL
.:: .. .: : . :: : . : .:.. :: : :: .. .. : :.. .. :::
NP_819 IGYFIGFSECLSATEGVFPVTHSVHTLLQVYFLWGHAKDIIQSFKTLERFGVIHSVFTNL
160 170 180 190 200 210
250 260 270 280 290
pF1KB7 LLWVLAVTNDSMHREIEAE-----LGIL-MEKSTGNETNTCLCLNATACEAFRRGFLMLY
:::. .: :.: :. : . ::. . ..: : : : : :. .:. .::
NP_819 LLWANGVLNESKHQLNEHKERLITLGFGNITTVLDDHTPQCNCTPPTLCTAISHGIYYLY
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB7 PFSTEYCLICCAVLFVMWKNVGRHVAPHMGAHPATAPFHLHGAIFGPLLGLLVLLAGVCV
::. :: .. ..:.:.:::.::.: :. : :. :.. : .::: :: : . :
NP_819 PFNIEYQILASTMLYVLWKNIGRKVDSHQ--HQKMQ-FKSDGVMVGAVLGLTVLAATIAV
280 290 300 310 320
360 370 380 390 400 410
pF1KB7 FVLFQIEASGPAIACQY-FTLYYAFYVAVLPTMSLACLAGTAIHGLEERELDTVKNPTRS
:.. :. . . . ..: . ...: :. : ::: :. ..:. :: :::.:.
NP_819 VVVYLIHIGRSKTKSESALIMFYLYAITLLMLMGAAGLAGIRIYRIDEKSLDESKNPARK
330 340 350 360 370 380
420 430 440 450 460 470
pF1KB7 LDVVLLMGAALGQMGIAYFSIVAIVAKRPHELLNRLILAYSLLLILQHIAQNLFIIEGLH
:: ::.:.: :. :.. ::.::. . : . : ::.: :... :::::.:..:
NP_819 LDSDLLVGTASGSWLISWGSILAILCAEGHPRYTWYNLPYSILAIVEKYIQNLFIFESIH
390 400 410 420 430 440
480 490 500 510
pF1KB7 RRP--LWE--------TVPEGLAGKQEAEPPRRGSLLE----LGQGLQRASLAYI-HSYS
:.: : : :: .: . . :. :.. . :. . :. . . :
NP_819 REPEKLSEDIQTLRVVTVCNGNTMPLASSCPKSGGVARDVAPQGKDMPPAANGNVCMRES
450 460 470 480 490 500
520 530 540 550
pF1KB7 H---------LNW-----------------KRRALKEISLFLILCNITLWMMPAFGIHPE
: .: ::..:..:. ::.::::.::. :::: .::
NP_819 HDKEEEKQEESSWGGSPSPVRLPRFLQGNAKRKVLRNIAAFLFLCNISLWIPPAFGCRPE
510 520 530 540 550 560
560 570 580 590
pF1KB7 FENGLEKDFYGYQIWFAIVNFGLPLGVFYRMHSVGGLVEVYLGA
..::::. .:.. :. .::...:...:::::....: :::
NP_819 YDNGLEEIVFGFEPWIIVVNLAMPFSIFYRMHAAASLFEVYCKI
570 580 590 600 610
596 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 06:18:17 2016 done: Fri Nov 4 06:18:18 2016
Total Scan time: 10.260 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]