Result of FASTA (omim) for
pFN21AB7205
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7205, 426 aa
1>>>pF1KB7205 426 - 426 aa - 426 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.7598+/-0.000313; mu= 11.5998+/- 0.020
mean_var=116.8307+/-23.183, 0's: 0 Z-trim(119.9): 18 B-trim: 13 in 1/52
Lambda= 0.118658
statistics sampled from 34554 (34572) to 34554 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.748), E-opt: 0.2 (0.405), width: 16
Scan time: 10.580
The best scores are: opt bits E(85289)
NP_149059 (OMIM: 606362) testicular acid phosphata ( 426) 2922 510.8 2.6e-144
NP_001601 (OMIM: 171650,200950) lysosomal acid pho ( 423) 1112 201.0 4.9e-51
NP_001289418 (OMIM: 171650,200950) lysosomal acid ( 395) 1072 194.1 5.3e-49
NP_001090 (OMIM: 171790) prostatic acid phosphatas ( 386) 1034 187.6 4.7e-47
XP_011511248 (OMIM: 171790) PREDICTED: prostatic a ( 387) 1034 187.6 4.8e-47
NP_001127666 (OMIM: 171790) prostatic acid phospha ( 418) 1034 187.6 5.1e-47
NP_001289419 (OMIM: 171650,200950) lysosomal acid ( 391) 942 171.8 2.6e-42
NP_001289421 (OMIM: 171650,200950) lysosomal acid ( 236) 514 98.4 2e-20
NP_001289420 (OMIM: 171650,200950) lysosomal acid ( 360) 513 98.4 3.2e-20
NP_001278966 (OMIM: 171790) prostatic acid phospha ( 353) 479 92.6 1.8e-18
XP_011511249 (OMIM: 171790) PREDICTED: prostatic a ( 385) 479 92.6 1.9e-18
NP_057445 (OMIM: 611471) lysophosphatidic acid pho ( 428) 211 46.7 0.00013
XP_016856911 (OMIM: 611471) PREDICTED: lysophospha ( 386) 209 46.4 0.00015
XP_011507903 (OMIM: 611471) PREDICTED: lysophospha ( 401) 209 46.4 0.00016
NP_001310554 (OMIM: 611471) lysophosphatidic acid ( 403) 209 46.4 0.00016
>>NP_149059 (OMIM: 606362) testicular acid phosphatase p (426 aa)
initn: 2922 init1: 2922 opt: 2922 Z-score: 2711.8 bits: 510.8 E(85289): 2.6e-144
Smith-Waterman score: 2922; 100.0% identity (100.0% similar) in 426 aa overlap (1-426:1-426)
10 20 30 40 50 60
pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVAS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 TLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 TLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 AGLFPEAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 AGLFPEAAPGSPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 GWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISAL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 DIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLALQGALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 DIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLALQGALG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 RFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 RFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLR
370 380 390 400 410 420
pF1KB7 ALGGPV
::::::
NP_149 ALGGPV
>>NP_001601 (OMIM: 171650,200950) lysosomal acid phospha (423 aa)
initn: 705 init1: 544 opt: 1112 Z-score: 1037.3 bits: 201.0 E(85289): 4.9e-51
Smith-Waterman score: 1112; 44.4% identity (68.9% similar) in 428 aa overlap (1-417:1-412)
10 20 30 40 50
pF1KB7 MAGL-GFWGHPAGPLLLLL---LLVLPP-RALPEGPLVFVALVFRHGDRAPLASYPMDPH
::: . :.. :. : ::: :.:.:: :: : ::.:..:::::.:. .:: ::.
NP_001 MAGKRSGWSR-AALLQLLLGVNLVVMPPTRA---RSLRFVTLLYRHGDRSPVKTYPKDPY
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 KEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLES
.: ::.:.:::: ::. :. :::. ::.::..::. :.:.:::.::::::::: :
NP_001 QEEE---WPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AQANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAA
:.:::::::: . .:. :.::::::::..::.::.::. ::::..: :. ..
NP_001 AEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTP
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 EYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRT
:::. . ::. . : :::. . :. .:.: :::.:.:.::: :: ::::....
NP_001 EYQNESSRNAQFLDMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 LAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTL
:.... ... : . ::::.: ::.:: : :.. . . :: :...:::::.::
NP_001 LSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 LALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPG
.::: :: .:.:. :::.: ::. . .:.:: .: ...::.: . : ::::::
NP_001 VALQMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPG
300 310 320 330 340
360 370 380 390 400
pF1KB7 CPAPCPLGRFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGL
:: ::: : .:: :. : :. :: .. . : .: . ... :.. .
NP_001 CPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLF
350 360 370 380 390 400
410 420
pF1KB7 GLLAWRPGCLRALGGPV
. : ::
NP_001 RMQAQPPGYRHVADGEDHA
410 420
>>NP_001289418 (OMIM: 171650,200950) lysosomal acid phos (395 aa)
initn: 787 init1: 543 opt: 1072 Z-score: 1000.7 bits: 194.1 E(85289): 5.3e-49
Smith-Waterman score: 1072; 44.4% identity (69.7% similar) in 390 aa overlap (34-417:8-384)
10 20 30 40 50 60
pF1KB7 LGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKEVASTLW
.:.: .:::::.:. .:: ::..: :
NP_001 MGVRMTEYVGL-YRHGDRSPVKTYPKDPYQE---EEW
10 20 30
70 80 90 100 110 120
pF1KB7 PRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANLAGL
:.:.:::: ::. :. :::. ::.::..::. :.:.:::.::::::::: ::.::::::
NP_001 PQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGL
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 FPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALEG
:: . .:. :.::::::::..::.::.::. ::::..: :. .. :::.
NP_001 FPPNGMQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSR
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 WTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISALD
. ::. . : :::. . :. .:.: :::.:.:.::: :: ::::.... :.... ..
NP_001 NAQFLDMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFS
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 IGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTLLALQGALG
. : . ::::.: ::.:: : :.. . . :: :...:::::.::.::: ::
NP_001 FRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTLVALQMALD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 LYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLG
.:.:. :::.: ::. . .:.:: .: ...::.: . : :::::::: :::
NP_001 VYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQ
280 290 300 310 320
370 380 390 400 410
pF1KB7 RFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPG
: .:: :. : :. :: .. . : .: . ... :.. . . : ::
NP_001 DFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPG
330 340 350 360 370 380
420
pF1KB7 CLRALGGPV
NP_001 YRHVADGEDHA
390
>>NP_001090 (OMIM: 171790) prostatic acid phosphatase is (386 aa)
initn: 972 init1: 307 opt: 1034 Z-score: 965.7 bits: 187.6 E(85289): 4.7e-47
Smith-Waterman score: 1034; 43.3% identity (70.6% similar) in 367 aa overlap (15-378:18-372)
10 20 30 40 50
pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE
.:.::. :.. : ::.::::::::.:. ..: :: ::
NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ
. ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::.
NP_001 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY
.:::.::: . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :.
NP_001 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL
:. :. . :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. :
NP_001 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA
..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. .
NP_001 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP
:: :: .:.: ::::.: :: . . :. : ..:::.. : : :: ::::
NP_001 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS
300 310 320 330 340
360 370 380 390 400 410
pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW
::: :: .:..:. : .. :
NP_001 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
350 360 370 380
>>XP_011511248 (OMIM: 171790) PREDICTED: prostatic acid (387 aa)
initn: 972 init1: 307 opt: 1034 Z-score: 965.7 bits: 187.6 E(85289): 4.8e-47
Smith-Waterman score: 1034; 43.3% identity (70.6% similar) in 367 aa overlap (15-378:18-372)
10 20 30 40 50
pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE
.:.::. :.. : ::.::::::::.:. ..: :: ::
XP_011 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ
. ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::.
XP_011 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY
.:::.::: . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :.
XP_011 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL
:. :. . :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. :
XP_011 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA
..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. .
XP_011 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP
:: :: .:.: ::::.: :: . . :. : ..:::.. : : :: ::::
XP_011 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS
300 310 320 330 340
360 370 380 390 400 410
pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW
::: :: .:..:. : .. :
XP_011 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGSSFHIQY
350 360 370 380
>>NP_001127666 (OMIM: 171790) prostatic acid phosphatase (418 aa)
initn: 950 init1: 307 opt: 1034 Z-score: 965.2 bits: 187.6 E(85289): 5.1e-47
Smith-Waterman score: 1034; 43.3% identity (70.6% similar) in 367 aa overlap (15-378:18-372)
10 20 30 40 50
pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE
.:.::. :.. : ::.::::::::.:. ..: :: ::
NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ
. ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::.
NP_001 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY
.:::.::: . . .: :.::::::::..::.:: .:.:.:::..:: :. .. :.
NP_001 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQLLYLPFRNCPRFQELESETLKSEEF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL
:. :. . :.. : ...:: :. : : :: : :.:...:.. ::.::. :.. :
NP_001 QKRLHPYKDFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA
..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. .
NP_001 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP
:: :: .:.: ::::.: :: . . :. : ..:::.. : : :: ::::
NP_001 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS
300 310 320 330 340
360 370 380 390 400 410
pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW
::: :: .:..:. : .. :
NP_001 PSCPLERFAELVGPVIPQDWSTECMTTNSHQVLKVIFAVAFCLISAVLMVLLFIHIRRGL
350 360 370 380 390 400
>>NP_001289419 (OMIM: 171650,200950) lysosomal acid phos (391 aa)
initn: 650 init1: 489 opt: 942 Z-score: 880.5 bits: 171.8 E(85289): 2.6e-42
Smith-Waterman score: 942; 42.1% identity (66.8% similar) in 385 aa overlap (40-417:5-380)
10 20 30 40 50 60
pF1KB7 PAGPLLLLLLLVLPPRALPEGPLVFVALVFRHG-DRAPLASYPMDPHKEVASTLWPRGLG
: : .:: : . . . : :.:
NP_001 MAGKRSGWSRAALLQLLLGVNLVVMPPTRARSLR
10 20 30
70 80 90 100 110 120
pF1KB7 QLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQANLAGLFPEAA
.: ::. :. :::. ::.::..::. :.:.:::.::::::::: ::.:::::::: .
NP_001 FVTLEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMSAEANLAGLFPPNG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 PG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEYQEALEGWTGFL
.:. :.::::::::..::.::.::. ::::..: :. .. :::. . ::
NP_001 MQRFNPNISWQPIPVHTVPITEDRLLKFPLGPCPRYEQLQNETRQTPEYQNESSRNAQFL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB7 SRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRTLAQISALDIGAHV
. . : :::. . :. .:.: :::.:.:.::: :: ::::.... :.... ...
NP_001 DMVANETGLTDL--TLETVWNVYDTLFCEQTHGLRLPPWASPQTMQRLSRLKDFSFRFLF
160 170 180 190 200 210
250 260 270 280 290 300
pF1KB7 GPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTLLALQGALGLYDGH
: . ::::.: ::.:: : :.. . . :: :...:::::.::.::: :: .:.:.
NP_001 GIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTLVALQMALDVYNGE
220 230 240 250 260 270
310 320 330 340 350 360
pF1KB7 TPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCPAPCPLGRFYQL
:::.: ::. . .:.:: .: ...::.: . : :::::::: ::: : .:
NP_001 QAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPGCPHRCPLQDFLRL
280 290 300 310 320
370 380 390 400 410 420
pF1KB7 TAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAWRPGCLRAL
: :. : :. :: .. . : .: . ... :.. . . : ::
NP_001 TEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLFRMQAQPPGYRHVA
330 340 350 360 370 380
pF1KB7 GGPV
NP_001 DGEDHA
390
>>NP_001289421 (OMIM: 171650,200950) lysosomal acid phos (236 aa)
initn: 493 init1: 332 opt: 514 Z-score: 487.7 bits: 98.4 E(85289): 2e-20
Smith-Waterman score: 514; 39.0% identity (64.9% similar) in 231 aa overlap (191-417:4-225)
170 180 190 200 210 220
pF1KB7 RYHELLREATEAAEYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGL
: :::. . :. .:.: :::.:.:.:::
NP_001 MVANETGLTDL--TLETVWNVYDTLFCEQTHGL
10 20 30
230 240 250 260 270
pF1KB7 PLPAWASPDVLRTLAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LP
:: ::::.... :.... ... : . ::::.: ::.:: : :.. . . ::
NP_001 RLPPWASPQTMQRLSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP
40 50 60 70 80 90
280 290 300 310 320 330
pF1KB7 LKMVMYSAHDSTLLALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRN
:...:::::.::.::: :: .:.:. :::.: ::. . .:.:: .: ...::
NP_001 -KLLVYSAHDTTLVALQMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRN
100 110 120 130 140
340 350 360 370 380 390
pF1KB7 DSAHLPLPLSLPGCPAPCPLGRFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLA
.: . : :::::::: ::: : .:: :. : :. :: .. . : .:
NP_001 ESDKAPWPLSLPGCPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSI
150 160 170 180 190 200
400 410 420
pF1KB7 GAVAVLVALSLGLGLLAWRPGCLRALGGPV
. ... :.. . . : ::
NP_001 LFLLIVLLLTVLFRMQAQPPGYRHVADGEDHA
210 220 230
>>NP_001289420 (OMIM: 171650,200950) lysosomal acid phos (360 aa)
initn: 719 init1: 295 opt: 513 Z-score: 484.1 bits: 98.4 E(85289): 3.2e-20
Smith-Waterman score: 814; 38.3% identity (58.6% similar) in 428 aa overlap (1-417:1-349)
10 20 30 40 50
pF1KB7 MAGL-GFWGHPAGPLLLLL---LLVLPP-RALPEGPLVFVALVFRHGDRAPLASYPMDPH
::: . :.. :. : ::: :.:.:: :: : ::.:..:::::.:. .:: ::.
NP_001 MAGKRSGWSR-AALLQLLLGVNLVVMPPTRARS---LRFVTLLYRHGDRSPVKTYPKDPY
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 KEVASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLES
.: ::.:.:::: ::. :. :::. ::.::..::. :.:.:::.::::::::: :
NP_001 QE---EEWPQGFGQLTKEGMLQHWELGQALRQRYHGFLNTSYHRQEVYVRSTDFDRTLMS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 AQANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAA
:.:::::::: . .:. :.::::::::..::.
NP_001 AEANLAGLFPPNGMQRFNPNISWQPIPVHTVPITEDR-----------------------
120 130 140 150
180 190 200 210 220 230
pF1KB7 EYQEALEGWTGFLSRLENFTGLSLVGEPLRRAWKVLDTLMCQQAHGLPLPAWASPDVLRT
:.::: :: ::::....
NP_001 ------------------------------------------QTHGLRLPPWASPQTMQR
160
240 250 260 270 280 290
pF1KB7 LAQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLG-LPLKMVMYSAHDSTL
:.... ... : . ::::.: ::.:: : :.. . . :: :...:::::.::
NP_001 LSRLKDFSFRFLFGIYQQAEKARLQGGVLLAQIRKNLTLMATTSQLP-KLLVYSAHDTTL
170 180 190 200 210 220
300 310 320 330 340 350
pF1KB7 LALQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPG
.::: :: .:.:. :::.: ::. . .:.:: .: ...::.: . : ::::::
NP_001 VALQMALDVYNGEQAPYASCHIFELYQ------EDSGNFSVEMYFRNESDKAPWPLSLPG
230 240 250 260 270 280
360 370 380 390 400
pF1KB7 CPAPCPLGRFYQLTAPARPPAHGVSCH---GPYEAAIPPAPVVPLLAGAVAVLVALSLGL
:: ::: : .:: :. : :. :: .. . : .: . ... :.. .
NP_001 CPHRCPLQDFLRLTEPVVPKDWQQECQLASGPADTEVIVALAVCGSILFLLIVLLLTVLF
290 300 310 320 330 340
410 420
pF1KB7 GLLAWRPGCLRALGGPV
. : ::
NP_001 RMQAQPPGYRHVADGEDHA
350 360
>>NP_001278966 (OMIM: 171790) prostatic acid phosphatase (353 aa)
initn: 833 init1: 307 opt: 479 Z-score: 452.8 bits: 92.6 E(85289): 1.8e-18
Smith-Waterman score: 862; 39.8% identity (63.8% similar) in 367 aa overlap (15-378:18-339)
10 20 30 40 50
pF1KB7 MAGLGFWGHPAGPLLLLLLLVLPPRALPEGPLVFVALVFRHGDRAPLASYPMDPHKE
.:.::. :.. : ::.::::::::.:. ..: :: ::
NP_001 MRAAPLLLARAASLSLGFLFLLFFWLDRSVLAKELKFVTLVFRHGDRSPIDTFPTDPIKE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 VASTLWPRGLGQLTTEGVRQQLELGRFLRSRYEAFLSPEYRREEVYIRSTDFDRTLESAQ
. ::.:.:::: :..:. :::...:.::. ::. :..:.::::::: :::: ::.
NP_001 SS---WPQGFGQLTQLGMEQHYELGEYIRKRYRKFLNESYKHEQVYIRSTDVDRTLMSAM
70 80 90 100 110
120 130 140 150 160 170
pF1KB7 ANLAGLFPEAAPG--SPEARWRPIPVHTVPVAEDKLLRFPMRSCPRYHELLREATEAAEY
.:::.::: . . .: :.::::::::..::.
NP_001 TNLAALFPPEGVSIWNPILLWQPIPVHTVPLSEDQ-------------------------
120 130 140 150
180 190 200 210 220 230
pF1KB7 QEALEGWTGFLSRLENFTGLSLVGEPLRRAW-KVLDTLMCQQAHGLPLPAWASPDVLRTL
:.. : ...:: :. : : :: : :.:...:.. ::.::. :.. :
NP_001 --------DFIATLGKLSGLH--GQDLFGIWSKVYDPLYCESVHNFTLPSWATEDTMTKL
160 170 180 190 200
240 250 260 270 280 290
pF1KB7 AQISALDIGAHVGPPRAAEKAQLTGGILLNAILANFSRVQRLGLPLKMVMYSAHDSTLLA
..: :.. . : . ::..: ::.:.: :: ...:. .. :..::::::.:. .
NP_001 RELSELSLLSLYGIHKQKEKSRLQGGVLVNEILNHMKRATQIPSYKKLIMYSAHDTTVSG
210 220 230 240 250 260
300 310 320 330 340 350
pF1KB7 LQGALGLYDGHTPPYAACLGFEFRKHLGNPAKDGGNVTVSLFYRNDSAHLPLPLSLPGCP
:: :: .:.: ::::.: :: . . :. : ..:::.. : : :: ::::
NP_001 LQMALDVYNGLLPPYASC-------HLTELYFEKGEYFVEMYYRNETQHEPYPLMLPGCS
270 280 290 300 310
360 370 380 390 400 410
pF1KB7 APCPLGRFYQLTAPARPPAHGVSCHGPYEAAIPPAPVVPLLAGAVAVLVALSLGLGLLAW
::: :: .:..:. : .. :
NP_001 PSCPLERFAELVGPVIPQDWSTECMTTNSHQGTEDSTD
320 330 340 350
426 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:57:10 2016 done: Fri Nov 4 05:57:12 2016
Total Scan time: 10.580 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]