Result of FASTA (ccds) for
pFN21AB7188
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7188, 462 aa
1>>>pF1KB7188 462 - 462 aa - 462 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5476+/-0.000786; mu= 12.9695+/- 0.048
mean_var=109.4977+/-22.179, 0's: 0 Z-trim(111.1): 6 B-trim: 0 in 0/51
Lambda= 0.122566
statistics sampled from 12094 (12098) to 12094 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.717), E-opt: 0.2 (0.372), width: 16
Scan time: 3.490
The best scores are: opt bits E(32554)
CCDS5942.1 SHH gene_id:6469|Hs108|chr7 ( 462) 3084 555.9 3.2e-158
CCDS33380.1 IHH gene_id:3549|Hs108|chr2 ( 411) 1342 247.8 1.5e-65
CCDS8779.1 DHH gene_id:50846|Hs108|chr12 ( 396) 1206 223.8 2.6e-58
>>CCDS5942.1 SHH gene_id:6469|Hs108|chr7 (462 aa)
initn: 3084 init1: 3084 opt: 3084 Z-score: 2954.1 bits: 555.9 E(32554): 3.2e-158
Smith-Waterman score: 3084; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KB7 MLLLARCLLLVLVSSLLVCSGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 MLLLARCLLLVLVSSLLVCSGLACGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 RYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 KLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 KLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 IHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 IHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDFLT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 FLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 FLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGPPSGGALG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 PRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 PRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILINRVL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 ASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS59 ASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTAPGA
370 380 390 400 410 420
430 440 450 460
pF1KB7 ADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS
::::::::::::::::::::::::::::::::::::::::::
CCDS59 ADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS
430 440 450 460
>>CCDS33380.1 IHH gene_id:3549|Hs108|chr2 (411 aa)
initn: 1657 init1: 1275 opt: 1342 Z-score: 1290.1 bits: 247.8 E(32554): 1.5e-65
Smith-Waterman score: 1583; 58.9% identity (74.2% similar) in 453 aa overlap (7-458:13-407)
10 20 30 40 50
pF1KB7 MLLLARCLLLVLVSSLLVCSGLACGPGRGFG-KRRHPKKLTPLAYKQFIPNVAE
::.:.:. :.: .. .::::: : .:: :.::.::::::: ::: :
CCDS33 MSPARLRPRLHFCLVLLLL--LVVPAAWGCGPGRVVGSRRRPPRKLVPLAYKQFSPNVPE
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 KTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISV
:::::::::::::.:.:::::::::::::::::::::::::::::::::::.::.:::::
CCDS33 KTLGASGRYEGKIARSSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDRLNSLAISV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 MNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWV
::::::::::::::::::::::::::::::::::::::::::.:::.:::::::::::::
CCDS33 MNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRNKYGLLARLAVEAGFDWV
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 YYESKAHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRL
:::::::.:::::.:.:.:::.:::::..: :.::.:. .. . ::::::: ..:
CCDS33 YYESKAHVHCSVKSEHSAAAKTGGCFPAGAQVRLESGARVALSAVRPGDRVLAMGEDGSP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 LYSDFLTFLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGP
.:: : ::::. ..: ::::..: .:: :: :::::.: :. : :: :
CCDS33 TFSDVLIFLDREPHRLRAFQVIETQDPPRRLALTPAHLLFTA---DNHT-EPAARF----
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 PSGGALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGT
:: :::.:.::: : .:: : : :: : .:. .. : ::::::: .::
CCDS33 --------RATFASHVQPGQYV-LVAGVPG---LQPARVAAVS-THVALGAYAPLTKHGT
300 310 320 330
360 370 380 390 400 410
pF1KB7 ILINRVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRV
.... :.:::.:.. .: :. :: :.:: :.:
CCDS33 LVVEDVVASCFAAVADHHLAQLAFWPLRLFHSL---------------------------
340 350 360 370
420 430 440 450 460
pF1KB7 ALTAPGAADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS
: :. .:: :.::: ::::..: ::. ..:::::.
CCDS33 ---AWGSW-TPGE----GVHWYPQLLYRLGRLLLEEGSFHPLGMSGAGS
380 390 400 410
>>CCDS8779.1 DHH gene_id:50846|Hs108|chr12 (396 aa)
initn: 1421 init1: 1126 opt: 1206 Z-score: 1160.4 bits: 223.8 E(32554): 2.6e-58
Smith-Waterman score: 1474; 54.4% identity (72.9% similar) in 450 aa overlap (1-447:1-395)
10 20 30 40 50
pF1KB7 MLLLARCLLLVLVSSLLVCSGLACGPGRG-FGKRRHPKK-LTPLAYKQFIPNVAEKTLGA
: ::. : : .. ::. . .:::::: :.::. .: :.:: ::::.:.: :.::::
CCDS87 MALLTNLLPLCCLA-LLALPAQSCGPGRGPVGRRRYARKQLVPLLYKQFVPGVPERTLGA
10 20 30 40 50
60 70 80 90 100 110
pF1KB7 SGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWP
:: ::...:.::::..:.::::::::::::::.:::::::.:::...:::::.:::.::
CCDS87 SGPAEGRVARGSERFRDLVPNYNPDIIFKDEENSGADRLMTERCKERVNALAIAVMNMWP
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB7 GVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESK
::.:::::::::::::...::::::::.:::::::::.:::.:::::::::::::::::.
CCDS87 GVRLRVTEGWDEDGHHAQDSLHYEGRALDITTSDRDRNKYGLLARLAVEAGFDWVYYESR
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB7 AHIHCSVKAENSVAAKSGGCFPGSATVHLEQGGTKLVKDLSPGDRVLAADDQGRLLYSDF
:.: ::::.::.:...::::::.:::.: .: : ...: :: ::::: .::.. .
CCDS87 NHVHVSVKADNSLAVRAGGCFPGNATVRLWSGERKGLRELHRGDWVLAADASGRVVPTPV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 LTFLDRDDGAKKVFYVIETREPRERLLLTAAHLLFVAPHNDSATGEPEASSGSGP-PSGG
: ::::: . : ..::. : ..:::: ::.:.: :: :. :
CCDS87 LLFLDRDLQRRASFVAVETEWPPRKLLLTPWHLVFAA---------------RGPAPAPG
240 250 260 270 280
300 310 320 330 340 350
pF1KB7 ALGPRALFASRVRPGQRVYVVAERDGDRRLLPAAVHSVTLSEEAAGAYAPLTAQGTILIN
..: .:: :.: :. : . : : :: : :. :::.:..:::::.::.:.:
CCDS87 DFAP--VFARRLRAGDSVLA----PGGDALRPARVARVA-REEAVGVFAPLTAHGTLLVN
290 300 310 320 330
360 370 380 390 400 410
pF1KB7 RVLASCYAVIEEHSWAHRAFAPFRLAHALLAALAPARTDRGGDSGGGDRGGGGGRVALTA
::::::::.: :.::::::::.:: ::: : :
CCDS87 DVLASCYAVLESHQWAHRAFAPLRLLHALGALL---------------------------
340 350 360 370
420 430 440 450 460
pF1KB7 PGAADAPGAGATAGIHWYSQLLYQIGTWLLDSEALHPLGMAVKSS
::.: : .:.::::.:::... ::
CCDS87 PGGAVQP-----TGMHWYSRLLYRLAEELLG
380 390
462 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:43:45 2016 done: Fri Nov 4 05:43:45 2016
Total Scan time: 3.490 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]