Result of FASTA (omim) for
pFN21AB7184
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7184, 221 aa
1>>>pF1KB7184 221 - 221 aa - 221 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1764+/-0.000326; mu= 14.4862+/- 0.020
mean_var=63.6611+/-12.766, 0's: 0 Z-trim(116.1): 25 B-trim: 28 in 1/52
Lambda= 0.160745
statistics sampled from 27038 (27063) to 27038 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.714), E-opt: 0.2 (0.317), width: 16
Scan time: 6.090
The best scores are: opt bits E(85289)
NP_001500 (OMIM: 603435) epididymal secretory glut ( 221) 1517 360.0 1.7e-99
NP_002075 (OMIM: 138321) glutathione peroxidase 3 ( 226) 1082 259.2 4.1e-69
NP_874360 (OMIM: 607913) glutathione peroxidase 6 ( 221) 1046 250.8 1.3e-66
NP_001316719 (OMIM: 138321) glutathione peroxidase ( 235) 1022 245.2 6.6e-65
NP_000572 (OMIM: 138320,614164) glutathione peroxi ( 203) 597 146.7 2.7e-35
NP_003987 (OMIM: 603435) epididymal secretory glut ( 100) 545 134.4 6.5e-32
NP_002074 (OMIM: 138319) glutathione peroxidase 2 ( 190) 540 133.4 2.5e-31
NP_001316384 (OMIM: 138320,614164) glutathione per ( 157) 382 96.7 2.3e-20
NP_056511 (OMIM: 615784) glutathione peroxidase 7 ( 187) 283 73.8 2.1e-13
NP_001316432 (OMIM: 138320,614164) glutathione per ( 170) 237 63.1 3.2e-10
NP_001034937 (OMIM: 138322,250220) phospholipid hy ( 234) 228 61.1 1.8e-09
NP_002076 (OMIM: 138322,250220) phospholipid hydro ( 197) 226 60.6 2.1e-09
NP_001034936 (OMIM: 138322,250220) phospholipid hy ( 227) 226 60.6 2.4e-09
NP_958799 (OMIM: 138320,614164) glutathione peroxi ( 98) 217 58.4 5e-09
NP_001316431 (OMIM: 138320,614164) glutathione per ( 104) 217 58.4 5.3e-09
>>NP_001500 (OMIM: 603435) epididymal secretory glutathi (221 aa)
initn: 1517 init1: 1517 opt: 1517 Z-score: 1907.1 bits: 360.0 E(85289): 1.7e-99
Smith-Waterman score: 1517; 100.0% identity (100.0% similar) in 221 aa overlap (1-221:1-221)
10 20 30 40 50 60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
130 140 150 160 170 180
190 200 210 220
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
:::::::::::::::::::::::::::::::::::::::::
NP_001 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
190 200 210 220
>>NP_002075 (OMIM: 138321) glutathione peroxidase 3 isof (226 aa)
initn: 1077 init1: 1077 opt: 1082 Z-score: 1361.7 bits: 259.2 E(85289): 4.1e-69
Smith-Waterman score: 1082; 70.5% identity (87.1% similar) in 217 aa overlap (1-217:1-217)
10 20 30 40 50 60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
:. :.. :: :::: ::. : ::: ::::: .::::.: :.... .::. ::::.
NP_002 MARLLQASCLLSLLLAGFVSQSRGQEKSKMDCHGGISGTIYEYGALTIDGEEYIPFKQYA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
::..::::::.:::::.:: ::::::::: :.:::.::::::::::::::.:.:::: ::
NP_002 GKYVLFVNVASYCGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGENSEILPTLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
::::::::::.:::::::::::::::: ..:::.::: ::.::: . :.:.::::::
NP_002 YVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFWEPMKVHDIR
130 140 150 160 170 180
190 200 210 220
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
::::::::::::::.::: ::.:::.:: :::.:...
NP_002 WNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK
190 200 210 220
>>NP_874360 (OMIM: 607913) glutathione peroxidase 6 prec (221 aa)
initn: 1028 init1: 1008 opt: 1046 Z-score: 1316.7 bits: 250.8 E(85289): 1.3e-66
Smith-Waterman score: 1046; 67.3% identity (88.2% similar) in 220 aa overlap (1-220:1-220)
10 20 30 40 50 60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
: :... :. ..:. :.: . : .. :.::.: ::::.: :..:: .::..:::..
NP_874 MFQQFQASCLVLFFLVGFAQQTLKPQNRKVDCNKGVTGTIYEYGALTLNGEEYIQFKQFA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
:::.::::::.::::.:::::::::::::: .:..::.:::::::::::: :.::: :::
NP_874 GKHVLFVNVAAYCGLAAQYPELNALQEELKNFGVIVLAFPCNQFGKQEPGTNSEILLGLK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
:: ::.:::::::::::::::::::::::.:::.::: :..::. ... :.:.::::::
NP_874 YVCPGSGFVPSFQLFEKGDVNGEKEQKVFTFLKNSCPPTSDLLGSSSQLFWEPMKVHDIR
130 140 150 160 170 180
190 200 210 220
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
::::::::::::.:::.: :.: ::.::.::: :::::.:
NP_874 WNFEKFLVGPDGVPVMHWFHQAPVSTVKSDILEYLKQFNTH
190 200 210 220
>>NP_001316719 (OMIM: 138321) glutathione peroxidase 3 i (235 aa)
initn: 1063 init1: 1016 opt: 1022 Z-score: 1286.3 bits: 245.2 E(85289): 6.6e-65
Smith-Waterman score: 1054; 67.7% identity (83.6% similar) in 226 aa overlap (1-217:1-226)
10 20 30 40 50
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMK---------MDCHKDEKGTIYDYEAIALNKN
:. :.. :: :::: ::. : ::: : :::: .::::.: :.... .
NP_001 MARLLQASCLLSLLLAGFVSQSRGQEKSKAPRQMGNPQMDCHGGISGTIYEYGALTIDGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB7 EYVSFKQYVGKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGD
::. ::::.::..::::::.:::::.:: ::::::::: :.:::.::::::::::::::.
NP_001 EYIPFKQYAGKYVLFVNVASYCGLTGQYIELNALQEELAPFGLVILGFPCNQFGKQEPGE
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 NKEILPGLKYVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISW
:.:::: ::::::::::::.:::::::::::::::: ..:::.::: ::.::: . :
NP_001 NSEILPTLKYVRPGGGFVPNFQLFEKGDVNGEKEQKFYTFLKNSCPPTSELLGTSDRLFW
130 140 150 160 170 180
180 190 200 210 220
pF1KB7 DPVKVHDIRWNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
.:.::::::::::::::::::::.::: ::.:::.:: :::.:...
NP_001 EPMKVHDIRWNFEKFLVGPDGIPIMRWHHRTTVSNVKMDILSYMRRQAALGVKRK
190 200 210 220 230
>>NP_000572 (OMIM: 138320,614164) glutathione peroxidase (203 aa)
initn: 561 init1: 350 opt: 597 Z-score: 754.6 bits: 146.7 E(85289): 2.7e-35
Smith-Waterman score: 597; 50.0% identity (73.9% similar) in 184 aa overlap (39-217:15-198)
10 20 30 40 50 60
pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN
..: . : : .: ::. . :: .:. :
NP_000 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIEN
10 20 30 40
70 80 90 100 110 120
pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGG
::. :: :.. : ..: ::..: : :::::::::::::.:: . :.::: .:::::::::
NP_000 VASLCGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQENAKNEEILNSLKYVRPGGG
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 FVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNF
: :.:.:::: .::: . .:.::... : ::. .. : :.:.:: .:. :::
NP_000 FEPNFMLFEKCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNF
110 120 130 140 150 160
190 200 210 220
pF1KB7 EKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
:::::::::.:. :.:.: . ... :: : :.:
NP_000 EKFLVGPDGVPLRRYSRRFQTIDIEPDIEALLSQGPSCA
170 180 190 200
>>NP_003987 (OMIM: 603435) epididymal secretory glutathi (100 aa)
initn: 560 init1: 545 opt: 545 Z-score: 694.0 bits: 134.4 E(85289): 6.5e-32
Smith-Waterman score: 545; 92.1% identity (96.6% similar) in 89 aa overlap (1-89:1-89)
10 20 30 40 50 60
pF1KB7 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MTTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 GKHILFVNVATYCGLTAQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
:::::::::::::::::::: ... :.:
NP_003 GKHILFVNVATYCGLTAQYPGMSVQGEDLYLVSSFLRKGM
70 80 90 100
>>NP_002074 (OMIM: 138319) glutathione peroxidase 2 [Hom (190 aa)
initn: 482 init1: 313 opt: 540 Z-score: 683.5 bits: 133.4 E(85289): 2.5e-31
Smith-Waterman score: 540; 46.4% identity (72.1% similar) in 183 aa overlap (39-216:7-187)
10 20 30 40 50 60
pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN
..:: ::.:. .: :.:. . :. .:. :
NP_002 MAFIAKSFYDLSAISLD-GEKVDFNTFRGRAVLIEN
10 20 30
70 80 90 100 110 120
pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGG
::. :: :.. . .:: :: .. : ::::::::::::.:: .:.::: .:::::::::
NP_002 VASLCGTTTRDFTQLNELQCRF-PRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB7 FVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNF
. :.: : .: .:::..:. ::..:: . :.: . .. : : :.::. :. :::
NP_002 YQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNF
100 110 120 130 140 150
190 200 210 220
pF1KB7 EKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
::::.::.: : :.:. . ... :: ::
NP_002 EKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI
160 170 180 190
>>NP_001316384 (OMIM: 138320,614164) glutathione peroxid (157 aa)
initn: 363 init1: 206 opt: 382 Z-score: 486.8 bits: 96.7 E(85289): 2.3e-20
Smith-Waterman score: 382; 49.6% identity (74.8% similar) in 115 aa overlap (107-217:38-152)
80 90 100 110 120 130
pF1KB7 AQYPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLKYVRPGGGFVPSFQLFE
.: . :.::: .:::::::::: :.:.:::
NP_001 AAAAAAQSVYAFSARPLAGGEPVSLGSLRGKENAKNEEILNSLKYVRPGGGFEPNFMLFE
10 20 30 40 50 60
140 150 160 170 180 190
pF1KB7 KGDVNGEKEQKVFSFLKHSCPHPSE----ILGTFKSISWDPVKVHDIRWNFEKFLVGPDG
: .::: . .:.::... : ::. .. : :.:.:: .:. ::::::::::::
NP_001 KCEVNGAGAHPLFAFLREALPAPSDDATALMTDPKLITWSPVCRNDVAWNFEKFLVGPDG
70 80 90 100 110 120
200 210 220
pF1KB7 IPVMRWSHRATVSSVKTDILAYLKQFKTK
.:. :.:.: . ... :: : :.:
NP_001 VPLRRYSRRFQTIDIEPDIEALLSQGPSCA
130 140 150
>>NP_056511 (OMIM: 615784) glutathione peroxidase 7 prec (187 aa)
initn: 212 init1: 153 opt: 283 Z-score: 361.5 bits: 73.8 E(85289): 2.1e-13
Smith-Waterman score: 327; 34.6% identity (61.7% similar) in 188 aa overlap (32-218:18-179)
10 20 30 40 50 60
pF1KB7 TTQLRVVHLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVG
: ..:. .::..:. . ... ::...: :
NP_056 MVAATVAAAWLLLWAAACAQQEQD-FYDFKAVNI-RGKLVSLEKYRG
10 20 30 40
70 80 90 100 110 120
pF1KB7 KHILFVNVATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEPGDNKEILPGLK
. : ::::. ::.: : : :. ::..: :. . ::.:::::::.::: .:::: .
NP_056 SVSLVVNVASECGFTDQHYRALQQLQRDLGPHHFNVLAFPCNQFGQQEPDSNKEI---ES
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 YVRPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIR
..: . :: .: : :.: . .:..: .. . .:.
NP_056 FARR--TYSVSFPMFSKIAVTGTGAHPAFKYLAQTSGK-------------EPT------
110 120 130 140
190 200 210 220
pF1KB7 WNFEKFLVGPDGIPVMRWSHRATVSSVKTDILAYLKQFKTK
::: :.::.::: : :. ..: :. .: : ....
NP_056 WNFWKYLVAPDGKVVGAWDPTVSVEEVRPQITALVRKLILLKREDL
150 160 170 180
>>NP_001316432 (OMIM: 138320,614164) glutathione peroxid (170 aa)
initn: 184 init1: 135 opt: 237 Z-score: 304.5 bits: 63.1 E(85289): 3.2e-10
Smith-Waterman score: 237; 42.0% identity (64.3% similar) in 112 aa overlap (39-144:15-125)
10 20 30 40 50 60
pF1KB7 HLLPLLLACFVQTSPKQEKMKMDCHKDEKGTIYDYEAIALNKNEYVSFKQYVGKHILFVN
..: . : : .: ::. . :: .:. :
NP_001 MCAARLAAAAAAAQSVYAFSARPLAGGEPVSLGSLRGKVLLIEN
10 20 30 40
70 80 90 100 110 120
pF1KB7 VATYCGLTAQ-YPELNALQEELKPYGLVVLGFPCNQFGKQEP----GDNKEILPG-LKYV
::. :: :.. : ..: ::..: : :::::::::::::.: : :. .: . . :
NP_001 VASLCGTTVRDYTQMNELQRRLGPRGLVVLGFPCNQFGHQLPFSPVGERQERRDSEFPQV
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 RPGGGFVPSFQLFEKGDVNGEKEQKVFSFLKHSCPHPSEILGTFKSISWDPVKVHDIRWN
::. .: . :: .: ::.
NP_001 RPAWWWVRA-QLHALREVRGERCGGAPSLRLPAGGPASSQRRRHRAYDRPQAHHLVSGVS
110 120 130 140 150 160
221 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:40:30 2016 done: Fri Nov 4 05:40:31 2016
Total Scan time: 6.090 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]