Result of FASTA (omim) for
pFN21AB7176
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7176, 365 aa
1>>>pF1KB7176 365 - 365 aa - 365 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.2082+/-0.000332; mu= -3.7959+/- 0.021
mean_var=353.1492+/-73.511, 0's: 0 Z-trim(125.5): 78 B-trim: 822 in 1/61
Lambda= 0.068249
statistics sampled from 49250 (49402) to 49250 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.844), E-opt: 0.2 (0.579), width: 16
Scan time: 8.860
The best scores are: opt bits E(85289)
NP_003914 (OMIM: 603621) forkhead box protein H1 [ ( 365) 2648 273.8 4.3e-73
NP_036318 (OMIM: 107250,601094,610256) forkhead bo ( 319) 426 55.0 2.8e-07
NP_001443 (OMIM: 603250) forkhead box protein F2 [ ( 444) 412 53.7 9.2e-07
NP_001444 (OMIM: 601090,601631,602482) forkhead bo ( 553) 405 53.1 1.7e-06
XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte ( 439) 379 50.5 8.7e-06
NP_004487 (OMIM: 602294) hepatocyte nuclear factor ( 472) 379 50.5 9.1e-06
NP_001442 (OMIM: 265380,601089) forkhead box prote ( 379) 364 48.9 2.2e-05
NP_004465 (OMIM: 602211) forkhead box protein D2 [ ( 495) 365 49.2 2.5e-05
NP_150285 (OMIM: 612788) forkhead box protein Q1 [ ( 403) 361 48.7 2.8e-05
NP_004464 (OMIM: 241850,602617,616534) forkhead bo ( 373) 357 48.2 3.5e-05
NP_004463 (OMIM: 601091) forkhead box protein D1 [ ( 465) 353 48.0 5.3e-05
NP_004109 (OMIM: 602939) forkhead box protein S1 [ ( 330) 347 47.2 6.3e-05
NP_004488 (OMIM: 602295) hepatocyte nuclear factor ( 350) 346 47.1 7e-05
NP_710141 (OMIM: 600288) hepatocyte nuclear factor ( 457) 326 45.3 0.00033
NP_068556 (OMIM: 600288) hepatocyte nuclear factor ( 463) 326 45.3 0.00033
NP_001129121 (OMIM: 612351) forkhead box protein I ( 420) 323 45.0 0.00038
NP_005242 (OMIM: 153400,602402) forkhead box prote ( 501) 323 45.0 0.00043
NP_005240 (OMIM: 164874,613454) forkhead box prote ( 489) 318 44.5 0.0006
NP_036320 (OMIM: 274600,600791,601093) forkhead bo ( 378) 315 44.1 0.00062
NP_954586 (OMIM: 611086) forkhead box protein D4-l ( 417) 316 44.3 0.00062
XP_011513493 (OMIM: 616302) PREDICTED: forkhead bo ( 570) 319 44.7 0.00062
NP_005241 (OMIM: 603252) forkhead box protein L1 [ ( 345) 313 43.9 0.00066
NP_954714 (OMIM: 611085) forkhead box protein D4-l ( 416) 314 44.1 0.00071
NP_997188 (OMIM: 601092) forkhead box protein D4 [ ( 439) 314 44.1 0.00073
NP_001032242 (OMIM: 616302) forkhead box protein K ( 733) 319 44.8 0.00074
NP_001445 (OMIM: 602291) forkhead box protein J1 [ ( 421) 311 43.8 0.00087
NP_036316 (OMIM: 611084) forkhead box protein D4-l ( 408) 309 43.6 0.00098
NP_036315 (OMIM: 607836,611539) forkhead box prote ( 478) 309 43.6 0.0011
NP_004505 (OMIM: 147685) forkhead box protein K2 [ ( 660) 310 43.9 0.0013
NP_075555 (OMIM: 110100,605597,608996) forkhead bo ( 376) 303 42.9 0.0014
XP_016856182 (OMIM: 616035) PREDICTED: forkhead bo ( 573) 290 41.8 0.0045
NP_001185781 (OMIM: 616035) forkhead box protein J ( 588) 290 41.9 0.0046
XP_006710522 (OMIM: 616035) PREDICTED: forkhead bo ( 596) 290 41.9 0.0047
XP_006710521 (OMIM: 616035) PREDICTED: forkhead bo ( 607) 290 41.9 0.0047
XP_011539328 (OMIM: 616035) PREDICTED: forkhead bo ( 622) 290 41.9 0.0048
NP_055762 (OMIM: 616035) forkhead box protein J3 i ( 622) 290 41.9 0.0048
NP_001185780 (OMIM: 616035) forkhead box protein J ( 622) 290 41.9 0.0048
NP_001185779 (OMIM: 616035) forkhead box protein J ( 622) 290 41.9 0.0048
XP_005270689 (OMIM: 616035) PREDICTED: forkhead bo ( 630) 290 41.9 0.0048
NP_658982 (OMIM: 274600,600791,601093) forkhead bo ( 283) 276 40.2 0.0072
>>NP_003914 (OMIM: 603621) forkhead box protein H1 [Homo (365 aa)
initn: 2648 init1: 2648 opt: 2648 Z-score: 1433.3 bits: 273.8 E(85289): 4.3e-73
Smith-Waterman score: 2648; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365)
10 20 30 40 50 60
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAMIALVIQAAPSRRLKLAQII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAMIALVIQAAPSRRLKLAQII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 RQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEAL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 RLQNTALCRRWQNGGARGAFAKDLGPYVLHGRPYRPPSPPPPPSEGFSIKSLLGGSGEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RLQNTALCRRWQNGGARGAFAKDLGPYVLHGRPYRPPSPPPPPSEGFSIKSLLGGSGEGA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PWPGLAPQSSPVPAGTGNSGEEAVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PWPGLAPQSSPVPAGTGNSGEEAVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 STLSPEPRAWPLHLLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 STLSPEPRAWPLHLLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 PQCPSTSPAYWGVAPETRGPPGLLCDLDALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 PQCPSTSPAYWGVAPETRGPPGLLCDLDALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLL
310 320 330 340 350 360
pF1KB7 SWCSL
:::::
NP_003 SWCSL
>>NP_036318 (OMIM: 107250,601094,610256) forkhead box pr (319 aa)
initn: 384 init1: 314 opt: 426 Z-score: 251.6 bits: 55.0 E(85289): 2.8e-07
Smith-Waterman score: 458; 37.3% identity (59.2% similar) in 260 aa overlap (14-245:52-301)
10 20 30 40
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAMIA
: .:. : ::..: :.. ::::.:.:.::
NP_036 VAPSGPPPSPLAGAEPGREPEEAAAGRGEAAPTPAPGPGRRRRRPLQRGKPPYSYIALIA
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB7 LVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQA
... ::.::: :: : : . : :.:.. . :..::::::. : :: :::..:..: .
NP_036 MALAHAPGRRLTLAAIYRFITERFAFYRDSPRKWQNSIRHNLTLNDCFVKVPREPGNP-G
90 100 110 120 130 140
110 120 130 140 150
pF1KB7 KGNFWAVDVSLIPAEALRLQNTALCRRWQ-----NGGARGAFAKDLGPYVLHGRPYRP-P
:::.:..: :: : ..: .. :: . . :..: : : . :: : :
NP_036 KGNYWTLD----PAAADMFDNGSFLRRRKRFKRAELPAHAAAAPG-PPLPFPYAPYAPAP
150 160 170 180 190
160 170 180 190 200
pF1KB7 SPP---PPPSEG---------FSIKSLLGG----SGEGAPWPGLAPQSSPVPAGTGNSGE
.: :::: : ::. ::.. .: ::: : ..: :...
NP_036 GPALLVPPPSAGPGPSPPARLFSVDSLVNLQPELAGLGAPEPPCC--AAPDAAAAAFPPC
200 210 220 230 240 250
210 220 230 240 250
pF1KB7 EAVPTPPLPSS--ERPLWPLC-PLPGPTRVEGETVQGG---AIGPSTLSPEPRAWPLHLL
:. .::: :. .: . : : ::: .: . .: :.:: :::
NP_036 AAAASPPLYSQVPDRLVLPATRPGPGPLPAEPLLALAGPAAALGP--LSPGEAYLRQPGF
260 270 280 290 300 310
260 270 280 290 300 310
pF1KB7 QGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVAP
NP_036 ASGLERYL
>>NP_001443 (OMIM: 603250) forkhead box protein F2 [Homo (444 aa)
initn: 361 init1: 303 opt: 412 Z-score: 242.4 bits: 53.7 E(85289): 9.2e-07
Smith-Waterman score: 412; 32.9% identity (54.9% similar) in 304 aa overlap (10-301:77-361)
10 20 30
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYL
: : . : :. .. : .::::.:.
NP_001 SSSSSSSASCASSSSSSNSASAPSAACKSAGGGGAGAGSGGAKKASSGLRRPEKPPYSYI
50 60 70 80 90 100
40 50 60 70 80 90
pF1KB7 AMIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPA
:.:...::..::.:: :..: . .:: ::::: :.:::.:.::::: :.:: :.:: .
NP_001 ALIVMAIQSSPSKRLTLSEIYQFLQARFPFFRGAYQGWKNSVRHNLSLNECFIKLPKGLG
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB7 KPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFA-KDLGPYVLHGRPYRPPS
.: .::..:..: :: . ... .. :: : : : : . :. : .
NP_001 RP-GKGHYWTID----PASEFMFEEGSF-RRRPRGFRRKCQALKPMYHRVVSGLGFGASL
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB7 PPP------PPSEGFSIKSLLGGSG-EGAPWPGLAPQSSPVPAGTGNSGEEAVP-TPPLP
: ::: .. .: : .: . : : ..: : . .. :: : :
NP_001 LPQGFDFQAPPSAPLGCHSQGGYGGLDMMPAGYDAGAGAPSHAHPHHHHHHHVPHMSPNP
230 240 250 260 270 280
220 230 240 250 260
pF1KB7 SSERPLWPLCPLP-GPTRVEGETVQGGA-IGP-STLSPEPRAWPLHLLQGTAVPGGRSSG
.: ::.: :: : . ::. :: :. :: : . : ...:. .:
NP_001 GST--YMASCPVPAGPGGVGAAGGGGGGDYGPDSSSSPVPSS-PA---MASAIEC-HSPY
290 300 310 320 330
270 280 290 300 310 320
pF1KB7 GHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVAPETRGPPGLLCDL
:. :.. : .: . .: : :.: :
NP_001 TSPAAHWSS------PGASPYLKQPPALTPSSNPAASAGLHSSMSSYSLEQSYLHQNARE
340 350 360 370 380
330 340 350 360
pF1KB7 DALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLLSWCSL
NP_001 DLSVGLPRYQHHSTPVCDRKDFVLNFNGISSFHPSASGSYYHHHHQSVCQDIKPCVM
390 400 410 420 430 440
>>NP_001444 (OMIM: 601090,601631,602482) forkhead box pr (553 aa)
initn: 366 init1: 277 opt: 405 Z-score: 237.5 bits: 53.1 E(85289): 1.7e-06
Smith-Waterman score: 409; 31.1% identity (52.2% similar) in 322 aa overlap (10-310:59-361)
10 20 30
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYL
: .: .: : . : ::::.:.
NP_001 AAAAAGGGYTAMPAPMSVYSHPAHAEQYPGGMARAYGPYTPQPQPKDMV----KPPYSYI
30 40 50 60 70 80
40 50 60 70 80 90
pF1KB7 AMIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPA
:.:...:: ::.... : : . .. :::.:.. .::..::::::: :.:: :::.:
NP_001 ALITMAIQNAPDKKITLNGIYQFIMDRFPFYRDNKQGWQNSIRHNLSLNECFVKVPRDDK
90 100 110 120 130 140
100 110 120 130 140 150
pF1KB7 KPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFAKDLGPYVLHGR----PYR
:: .::..:..: : ..: .. :: . . : :: . : :
NP_001 KP-GKGSYWTLD----PDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKEPPPPGR
150 160 170 180 190
160 170 180 190 200
pF1KB7 --PPSPP-----------PPPSEGFSIKSLLGGSGEGAPWPGLAPQSSPVPAGTGNSGEE
::.:: ::: . .::. .:. . : : :.: :. :...
NP_001 QPPPAPPEQADGNAPGPQPPPVRIQDIKTE-NGTCPSPPQP-LSPA-----AALGSGSAA
200 210 220 230 240 250
210 220 230 240 250
pF1KB7 AVPTPPLP-SSERPLWPLCPLPG--PTRVEGETVQGGAIGPSTLSPEPRAWPLHLLQGTA
::: : :: : :: :. .. ...:. .: : : : : : :: .
NP_001 AVPKIESPDSSSSSLSSGSSPPGSLPS-ARPLSLDGADSAPP--PPAPSAPPPHHSQGFS
260 270 280 290 300
260 270 280 290 300 310
pF1KB7 VPGGRSS-GGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVAPETR
: . .: : : ..: .. : . . .::: . :. : :
NP_001 VDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYSSPCSQTS
310 320 330 340 350 360
320 330 340 350 360
pF1KB7 GPPGLLCDLDALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLLSWCSL
NP_001 SAGSSGGGGGGAGAAGGAGGAGTYHCNLQAMSLYAAGERGGHLQGAPGGAGGSAVDDPLP
370 380 390 400 410 420
>>XP_016876735 (OMIM: 602294) PREDICTED: hepatocyte nucl (439 aa)
initn: 351 init1: 273 opt: 379 Z-score: 224.9 bits: 50.5 E(85289): 8.7e-06
Smith-Waterman score: 384; 33.3% identity (56.1% similar) in 246 aa overlap (1-224:101-332)
10 20
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRK-----
:.:: . : : .::. . :
XP_016 MGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMS-----PMAYAPSNLGRSRAGGGGD
80 90 100 110 120
30 40 50 60 70 80
pF1KB7 ----KRYLRHDKPPYTYLAMIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSI
:: : ::::.:...:...:: :::. : :..: . .. .::..:.. . :..::
XP_016 AKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSI
130 140 150 160 170 180
90 100 110 120 130
pF1KB7 RHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQ------NGG
::.:: : :: :: ..: :: .::..: .: : . ..: :: . . :
XP_016 RHSLSFNDCFVKVARSPDKP-GKGSYW----TLHPDSGNMFENGCYLRRQKRFKCEKQPG
190 200 210 220 230 240
140 150 160 170 180
pF1KB7 ARGAFAKDLGPYVLHGRP--YRPPSPPPPPSEGFSI-KSLLGGSG--EGAPWPGLA--PQ
: :. .. : .: : . :: :: . ... : .: :::: :: : ::
XP_016 AGGGGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQ
250 260 270 280 290 300
190 200 210 220 230 240
pF1KB7 SSPVPAGTGNSGEEAVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGPSTLSPEPR
. ..:...: . :: :: : :. ::
XP_016 TLDHSGATATGGASELKTPA--SSTAP--PISSGPGALASVPASHPAHGLAPHESQLHLK
310 320 330 340 350
250 260 270 280 290 300
pF1KB7 AWPLHLLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSP
XP_016 GDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSP
360 370 380 390 400 410
>>NP_004487 (OMIM: 602294) hepatocyte nuclear factor 3-a (472 aa)
initn: 351 init1: 273 opt: 379 Z-score: 224.5 bits: 50.5 E(85289): 9.1e-06
Smith-Waterman score: 384; 33.3% identity (56.1% similar) in 246 aa overlap (1-224:134-365)
10 20
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRK-----
:.:: . : : .::. . :
NP_004 MGTALSPSGMGAMGAQQAASMNGLGPYAAAMNPCMS-----PMAYAPSNLGRSRAGGGGD
110 120 130 140 150
30 40 50 60 70 80
pF1KB7 ----KRYLRHDKPPYTYLAMIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSI
:: : ::::.:...:...:: :::. : :..: . .. .::..:.. . :..::
NP_004 AKTFKRSYPHAKPPYSYISLITMAIQQAPSKMLTLSEIYQWIMDLFPYYRQNQQRWQNSI
160 170 180 190 200 210
90 100 110 120 130
pF1KB7 RHNLSSNRCFRKVPKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQ------NGG
::.:: : :: :: ..: :: .::..: .: : . ..: :: . . :
NP_004 RHSLSFNDCFVKVARSPDKP-GKGSYW----TLHPDSGNMFENGCYLRRQKRFKCEKQPG
220 230 240 250 260 270
140 150 160 170 180
pF1KB7 ARGAFAKDLGPYVLHGRP--YRPPSPPPPPSEGFSI-KSLLGGSG--EGAPWPGLA--PQ
: :. .. : .: : . :: :: . ... : .: :::: :: : ::
NP_004 AGGGGGSGSGGSGAKGGPESRKDPSGASNPSADSPLHRGVHGKTGQLEGAPAPGPAASPQ
280 290 300 310 320 330
190 200 210 220 230 240
pF1KB7 SSPVPAGTGNSGEEAVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGPSTLSPEPR
. ..:...: . :: :: : :. ::
NP_004 TLDHSGATATGGASELKTPA--SSTAP--PISSGPGALASVPASHPAHGLAPHESQLHLK
340 350 360 370 380
250 260 270 280 290 300
pF1KB7 AWPLHLLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSP
NP_004 GDPHYSFNHPFSINNLMSSSEQQHKLDFKAYEQALQYSPYGSTLPASLPLGSASVTTRSP
390 400 410 420 430 440
>>NP_001442 (OMIM: 265380,601089) forkhead box protein F (379 aa)
initn: 333 init1: 290 opt: 364 Z-score: 217.7 bits: 48.9 E(85289): 2.2e-05
Smith-Waterman score: 389; 29.2% identity (53.7% similar) in 322 aa overlap (2-305:18-337)
10 20 30 40
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAMIAL
: .:. : . .::. :. . : .::::.:.:.:..
NP_001 MSSAPEKQQPPHGGGGGGGGGGGAAMDPASSGPSKA-KKTNAGIRRPEKPPYSYIALIVM
10 20 30 40 50
50 60 70 80 90 100
pF1KB7 VIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKPQAK
.::..:..:: :..: . .:. ::::: .:.:::.:.::::: :.:: :.:: ..: .:
NP_001 AIQSSPTKRLTLSEIYQFLQSRFPFFRGSYQGWKNSVRHNLSLNECFIKLPKGLGRP-GK
60 70 80 90 100 110
110 120 130 140 150
pF1KB7 GNFWAVDVS---LIPAEALRLQNTALCRRWQNGGARGAFAKDLG----P--YVLHGRPYR
:..:..: . .. ..: . .. :. : .. . :: : : ..:
NP_001 GHYWTIDPASEFMFEEGSFRRRPRGFRRKCQALKPMYSMMNGLGFNHLPDTYGFQGSAGG
120 130 140 150 160 170
160 170 180 190 200
pF1KB7 PPSPPPPPS-EGF--SIKSLLGGSGEGAPWPGLAPQSSPVPAG---TGNSGEEAVPTPPL
:: . :: ... : :. .: :. . : .: :. : :. :
NP_001 LSCPPNSLALEGGLGMMNGHLPGNVDGMALPSHSVPHLPSNGGHSYMGGCGGAAAGEYPH
180 190 200 210 220 230
210 220 230 240 250 260
pF1KB7 PSSERPLWPLCPLPGPTRVEGETVQGG--AIGPSTLSPEPRAWPLHLLQGTAVPGGRSSG
.: : :: : . .: ..: .: : : . : . .. : : . ...
NP_001 HDSSVPASPLLPTGAGGVMEPHAVYSGSAAAWPPSASAALNSGASYIKQQPLSPCNPAAN
240 250 260 270 280 290
270 280 290 300 310 320
pF1KB7 GHRASLWGQ-LPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVAPETRGPPGLLCD
.:: . : :: . :. : : : ::
NP_001 PLSGSLSTHSLEQPYLHQNSHNAPAELQGIPRYHSQSPSMCDRKEFVFSFNAMASSSMHS
300 310 320 330 340 350
330 340 350 360
pF1KB7 LDALFQGVPPNKSIYDVWVSHPRDLAAPGPGWLLSWCSL
NP_001 AGGGSYYHQQVTYQDIKPCVM
360 370
>>NP_004465 (OMIM: 602211) forkhead box protein D2 [Homo (495 aa)
initn: 395 init1: 266 opt: 365 Z-score: 216.8 bits: 49.2 E(85289): 2.5e-05
Smith-Waterman score: 375; 31.0% identity (52.8% similar) in 271 aa overlap (5-254:108-356)
10 20 30
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKP
.: ::: . . .. : ::
NP_004 SDGEPRALASRGAAAAAGSPGPGAAAARGAAGPGPGPPSGGAATRSPLV---------KP
80 90 100 110 120
40 50 60 70 80 90
pF1KB7 PYTYLAMIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKV
::.:.:.:...: .:..:: :..: . ... ::..:: . .:..::::::: : :: :.
NP_004 PYSYIALITMAILQSPKKRLTLSEICEFISGRFPYYREKFPAWQNSIRHNLSLNDCFVKI
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB7 PKDPAKPQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFAKD-LGPYVLHGRP
:..:..: .:::.:..: : : ..: .. :: : : .. : : : .:
NP_004 PREPGNP-GKGNYWTLD----PESADMFDNGSFLRR------RKRFKRQPLPPPHPHPHP
190 200 210 220 230
160 170 180 190
pF1KB7 Y---------RPPSPPPPPSEGFSIKSLLG-GSG-----EGAPWPGLAPQSSPVPAGTGN
. . : ::. . : : : ::: :: ::. : : . .
NP_004 HPELLLRGGAAAAGDPGAFLPGFAAYGAYGYGYGLALPAYGAPPPGPAPHPHPHPHAFAF
240 250 260 270 280 290
200 210 220 230 240 250
pF1KB7 SGEEAVPTPPLPSSERPLWPLCPLPGPTRVEGETVQGGAIGPSTLS-----PEPRAWPLH
.. :. . : : : : ::: . . :.: .:. : : : . :
NP_004 AA--AAAAAPCQLSVPPGRAAAPPPGPPTASVFAGAGSAPAPAPASGSGPGPGPAGLPAF
300 310 320 330 340 350
260 270 280 290 300 310
pF1KB7 LLQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGV
:
NP_004 LGAELGCAKAFYAASLSPPAAGTAAGLPTALLRQGLKTDAGGGAGGGGAGAGQRPSFSID
360 370 380 390 400 410
>>NP_150285 (OMIM: 612788) forkhead box protein Q1 [Homo (403 aa)
initn: 352 init1: 323 opt: 361 Z-score: 215.8 bits: 48.7 E(85289): 2.8e-05
Smith-Waterman score: 398; 32.0% identity (54.0% similar) in 278 aa overlap (12-262:98-369)
10 20 30 40
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLAM
: : . .. :.: : :. ::::.:.:.
NP_150 AGGGPGAEEAIPAAAAAAVVAEGAEAGAAGPGAGGAGSGEGARSKPYTRRPKPPYSYIAL
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB7 IALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAKP
::..:. . . :: ::.: . ... ::::: .: ::..:.::::: : :: :: .::..:
NP_150 IAMAIRDSAGGRLTLAEINEYLMGKFPFFRGSYTGWRNSVRHNLSLNDCFVKVLRDPSRP
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB7 QAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAF-AKDLGPYVLHGRPYRPPSPP
.: :.: .. : . . .. :: . . :. : : : : : :: :
NP_150 WGKDNYWMLN----PNSEYTFADGVFRRRRKRLSHRAPVPAPGLRPEEAPGLPAAPPPAP
190 200 210 220 230 240
170 180 190 200
pF1KB7 PPPSEGF---SIKSLLGGSGEGAPWPGLAPQS---SP---------VPAGTGNSGEEAVP
:. .. .: : ..: .: .: .:. : . : :.:
NP_150 AAPASPRMRSPARQEERASPAGKFSSSFAIDSILRKPFRSRRLRDTAPGTTLQWG--AAP
250 260 270 280 290 300
210 220 230 240 250
pF1KB7 TPPLPSSE--------RPLWPLCPLPG--PTRVEGETVQGGAIGPSTL-SPEPRAWPLHL
::::. : : ::: . :.:. .. .. .: : .: : : : .
NP_150 CPPLPAFPALLPAAPCRALLPLCAYGAGEPARLGAREAEVPPTAPPLLLAPLPAAAPAKP
310 320 330 340 350 360
260 270 280 290 300 310
pF1KB7 LQGTAVPGGRSSGGHRASLWGQLPTSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVA
:.: :. :
NP_150 LRGPAAGGAHLYCPLRLPAALQAASVRRPGPHLPYPVETLLA
370 380 390 400
>>NP_004464 (OMIM: 241850,602617,616534) forkhead box pr (373 aa)
initn: 365 init1: 292 opt: 357 Z-score: 214.1 bits: 48.2 E(85289): 3.5e-05
Smith-Waterman score: 400; 29.9% identity (51.3% similar) in 318 aa overlap (10-320:30-306)
10 20 30 40
pF1KB7 MGPCSGSRLGPPEAESPSQPPKRRKKRYLRHDKPPYTYLA
: : . ::.:: :.. ::::.:.:
NP_004 MTAESGPPPPQPEVLATVKEERGETAAGAGVPGEATGRGAGGRRRKRPLQRGKPPYSYIA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB7 MIALVIQAAPSRRLKLAQIIRQVQAVFPFFREDYEGWKDSIRHNLSSNRCFRKVPKDPAK
.::..: :: ::: :. : . . :::.:.. . :..::::::. : :: :.:.. ..
NP_004 LIAMAIAHAPERRLTLGGIYKFITERFPFYRDNPKKWQNSIRHNLTLNDCFLKIPREAGR
70 80 90 100 110 120
110 120 130 140 150
pF1KB7 PQAKGNFWAVDVSLIPAEALRLQNTALCRRWQNGGARGAFAK-DLGPYVLHGRPYRPPSP
: .:::.::.: : ... .. :: : : . ::. : :
NP_004 P-GKGNYWALD----PNAEDMFESGSFLRR------RKRFKRSDLSTY-----------P
130 140 150
160 170 180 190 200 210
pF1KB7 PPPPSEGFSIKSLLGGSGEGAPWPGLAPQSSPVPAGTGNSGEEAVPTPPLPSSERPLWPL
. . . . .... .: .:: .: . : :. .: .:: .. :..
NP_004 AYMHDAAAAAAAAAAAAAAAAIFPGAVPAARPPYPGAVYAGY----APPSLAAPPPVYYP
160 170 180 190 200 210
220 230 240 250 260 270
pF1KB7 CPLPGPTRVEGETVQGGAIGPSTLSPEPRAWPLHLLQGTAVPGGR---SSGGHRASLWGQ
::: :: : . :::: : .: ::: .:.: :. :
NP_004 AASPGPCRVFG------LVPERPLSPELGPAP----SG---PGGSCAFASAGAPATTTGY
220 230 240 250 260
280 290 300 310 320 330
pF1KB7 LP---TSYLPIYTPNVVMPLAPPPTSCPQCPSTSPAYWGVAPETRGPPGLLCDLDALFQG
: :. : . : : . :: ... : ...: . ::
NP_004 QPAGCTGARPANPSAYAAAYAGPDGAYPQ--GAGSAIFAAAGRLAGPASPPAGGSSGGVE
270 280 290 300 310
340 350 360
pF1KB7 VPPNKSIYDVWVSHPRDLAAPGPGWLLSWCSL
NP_004 TTVDFYGRTSPGQFGALGACYNPGGQLGGASAGAYHARHAAAYPGGIDRFVSAM
320 330 340 350 360 370
365 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:37:34 2016 done: Fri Nov 4 05:37:35 2016
Total Scan time: 8.860 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]