Result of FASTA (omim) for
pFN21AB7169
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7169, 433 aa
1>>>pF1KB7169 433 - 433 aa - 433 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7772+/-0.000364; mu= 6.1555+/- 0.023
mean_var=145.5854+/-29.009, 0's: 0 Z-trim(117.8): 48 B-trim: 306 in 1/52
Lambda= 0.106296
statistics sampled from 30110 (30160) to 30110 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.354), width: 16
Scan time: 10.120
The best scores are: opt bits E(85289)
XP_011507718 (OMIM: 116200,600897,612474) PREDICTE ( 433) 2876 452.7 8.4e-127
NP_005258 (OMIM: 116200,600897,612474) gap junctio ( 433) 2876 452.7 8.4e-127
XP_011507719 (OMIM: 116200,600897,612474) PREDICTE ( 427) 2840 447.2 3.8e-125
XP_011533350 (OMIM: 121015,601885) PREDICTED: gap ( 435) 1175 191.9 2.8e-48
NP_068773 (OMIM: 121015,601885) gap junction alpha ( 435) 1175 191.9 2.8e-48
XP_016856533 (OMIM: 108770,121013,612474,614049) P ( 358) 1032 169.9 9.6e-42
NP_005257 (OMIM: 108770,121013,612474,614049) gap ( 358) 1032 169.9 9.6e-42
XP_005273008 (OMIM: 108770,121013,612474,614049) P ( 358) 1032 169.9 9.6e-42
NP_859054 (OMIM: 108770,121013,612474,614049) gap ( 358) 1032 169.9 9.6e-42
NP_115991 (OMIM: 611924) gap junction alpha-10 pro ( 543) 955 158.2 4.9e-38
NP_110399 (OMIM: 611923) gap junction alpha-9 prot ( 515) 945 156.6 1.3e-37
NP_000156 (OMIM: 104100,121014,133200,164200,18610 ( 382) 900 149.7 1.3e-35
XP_016856532 (OMIM: 121012) PREDICTED: gap junctio ( 333) 881 146.7 8.5e-35
NP_002051 (OMIM: 121012) gap junction alpha-4 prot ( 333) 881 146.7 8.5e-35
XP_005270807 (OMIM: 121012) PREDICTED: gap junctio ( 333) 881 146.7 8.5e-35
NP_003995 (OMIM: 121011,124500,148210,148350,14920 ( 226) 501 88.3 2.1e-17
XP_011533351 (OMIM: 121011,124500,148210,148350,14 ( 226) 501 88.3 2.1e-17
NP_699199 (OMIM: 611922) gap junction delta-4 prot ( 370) 495 87.5 6.1e-17
NP_001103689 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
XP_016875846 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
XP_016875848 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
NP_006774 (OMIM: 129500,220290,304400,604418,61264 ( 261) 488 86.4 9.6e-17
XP_016875847 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
XP_016875849 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
NP_001103691 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
NP_001103690 (OMIM: 129500,220290,304400,604418,61 ( 261) 488 86.4 9.6e-17
NP_001091111 (OMIM: 302800,304040) gap junction be ( 283) 464 82.7 1.3e-15
XP_011529209 (OMIM: 302800,304040) PREDICTED: gap ( 283) 464 82.7 1.3e-15
XP_016884897 (OMIM: 302800,304040) PREDICTED: gap ( 283) 464 82.7 1.3e-15
NP_000157 (OMIM: 302800,304040) gap junction beta- ( 283) 464 82.7 1.3e-15
NP_076872 (OMIM: 133200,220290,603324,612644) gap ( 270) 463 82.5 1.4e-15
NP_001005752 (OMIM: 133200,220290,603324,612644) g ( 270) 463 82.5 1.4e-15
NP_694944 (OMIM: 133200,605425) gap junction beta- ( 266) 462 82.4 1.5e-15
XP_011538981 (OMIM: 133200,605425) PREDICTED: gap ( 266) 462 82.4 1.5e-15
XP_005256978 (OMIM: 608655) PREDICTED: gap junctio ( 396) 464 82.8 1.7e-15
NP_005488 (OMIM: 608655) gap junction gamma-1 prot ( 396) 464 82.8 1.7e-15
XP_005256977 (OMIM: 608655) PREDICTED: gap junctio ( 396) 464 82.8 1.7e-15
NP_001073852 (OMIM: 608655) gap junction gamma-1 p ( 396) 464 82.8 1.7e-15
NP_065168 (OMIM: 608803,608804,613206,613480) gap ( 439) 452 81.0 6.8e-15
XP_005270808 (OMIM: 604493) PREDICTED: gap junctio ( 273) 442 79.3 1.3e-14
NP_005259 (OMIM: 604493) gap junction beta-5 prote ( 273) 442 79.3 1.3e-14
NP_065711 (OMIM: 607058) gap junction delta-2 prot ( 321) 433 78.0 3.9e-14
NP_940970 (OMIM: 611921) gap junction beta-7 prote ( 223) 425 76.7 6.8e-14
XP_005248773 (OMIM: 611921) PREDICTED: gap junctio ( 223) 425 76.7 6.8e-14
NP_689343 (OMIM: 607425) gap junction delta-3 prot ( 294) 399 72.8 1.4e-12
XP_016877927 (OMIM: 607058) PREDICTED: gap junctio ( 270) 368 68.0 3.4e-11
NP_853516 (OMIM: 611925) gap junction gamma-3 prot ( 279) 355 66.0 1.4e-10
>>XP_011507718 (OMIM: 116200,600897,612474) PREDICTED: g (433 aa)
initn: 2876 init1: 2876 opt: 2876 Z-score: 2397.5 bits: 452.7 E(85289): 8.4e-127
Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
370 380 390 400 410 420
430
pF1KB7 KASSRARSDDLTV
:::::::::::::
XP_011 KASSRARSDDLTV
430
>>NP_005258 (OMIM: 116200,600897,612474) gap junction al (433 aa)
initn: 2876 init1: 2876 opt: 2876 Z-score: 2397.5 bits: 452.7 E(85289): 8.4e-127
Smith-Waterman score: 2876; 100.0% identity (100.0% similar) in 433 aa overlap (1-433:1-433)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
370 380 390 400 410 420
430
pF1KB7 KASSRARSDDLTV
:::::::::::::
NP_005 KASSRARSDDLTV
430
>>XP_011507719 (OMIM: 116200,600897,612474) PREDICTED: g (427 aa)
initn: 2840 init1: 2840 opt: 2840 Z-score: 2367.7 bits: 447.2 E(85289): 3.8e-125
Smith-Waterman score: 2840; 100.0% identity (100.0% similar) in 427 aa overlap (1-427:1-427)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRPV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFNQF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAERLTTEE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB7 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPELTTDDARPLSRLS
370 380 390 400 410 420
430
pF1KB7 KASSRARSDDLTV
:::::::
XP_011 KASSRAR
>>XP_011533350 (OMIM: 121015,601885) PREDICTED: gap junc (435 aa)
initn: 1171 init1: 657 opt: 1175 Z-score: 987.7 bits: 191.9 E(85289): 2.8e-48
Smith-Waterman score: 1175; 45.6% identity (66.2% similar) in 447 aa overlap (1-433:1-435)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
:::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
XP_011 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
:::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ...
XP_011 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
. : : . .: ..: . :. :.:::::. .::::::::::::.:.::::::.. :
XP_011 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....
XP_011 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
. .: : . . .. . . . :: .. : .: :: :
XP_011 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 N--QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAER
. . : . : . : :... : . . . : .: . ::: . : : .. .
XP_011 KLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALK-AYPAASTPAAPSPV
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 LTT-----EEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPE
.. .: : :.: .: : : :: .. .. . :
XP_011 GSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PP
360 370 380 390 400
410 420 430
pF1KB7 LTTDDARPLSRLSKASS-RARSDDLTV
: : :. :.::: ::: .::..
XP_011 LPLGDPGRASKASRASSGRARPEDLAI
410 420 430
>>NP_068773 (OMIM: 121015,601885) gap junction alpha-3 p (435 aa)
initn: 1171 init1: 657 opt: 1175 Z-score: 987.7 bits: 191.9 E(85289): 2.8e-48
Smith-Waterman score: 1175; 45.6% identity (66.2% similar) in 447 aa overlap (1-433:1-435)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
:::::::: .::...:::::::.::::::::::::.::.::: :::::::::.:::::::
NP_068 MGDWSFLGRLLENAQEHSTVIGKVWLTVLFIFRILVLGAAAEDVWGDEQSDFTCNTQQPG
10 20 30 40 50 60
70 80 90 100 110
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEE-LGQQAG
:::::::.::::::::.:.:::::::::.:.:.::..: ::::::.: :: :: : ...
NP_068 CENVCYDRAFPISHIRFWALQIIFVSTPTLIYLGHVLHIVRMEEKKKEREEEEQLKRESP
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB7 TNGGPDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRILP
. : : . .: ..: . :. :.:::::. .::::::::::::.:.::::::.. :
NP_068 SPKEPPQDN-PSSRDDRG--RVRMAGALLRTYVFNIIFKTLFEVGFIAGQYFLYGFELKP
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKRP
::::.::::::.::::.::::::::::.:::.:: .::.::..:. ::: : .....
NP_068 LYRCDRWPCPNTVDCFISRPTEKTIFIIFMLAVACASLLLNMLEIYHLGWKKLKQGVTSR
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB7 VEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMV--ETSPLPAKPF
. .: : . . .. . . . :: .. : .: :: :
NP_068 LGPDASEAPLGTADPPPLPPSSRPPAVAIGFPPYYAHTAAPLGQARAVGYPGAPPPAADF
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB7 N--QFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEEGAEPEVGEKKEEAER
. . : . : . : :... : . . . : .: . ::: . : : .. .
NP_068 KLLALTEARGKGQSAKLYNGHHHLLMTEQNWANQAAERQ-PPALK-AYPAASTPAAPSPV
300 310 320 330 340 350
360 370 380 390 400
pF1KB7 LTT-----EEQEKVAVP---EGEKVETPGVDKEGEKEEPQSEKVSKQGLPAEKTPSLCPE
.. .: : :.: .: : : :: .. .. . :
NP_068 GSSSPPLAHEAEAGAAPLLLDGSGSSLEGSALAGTPEEEEQAVTTAAQMHQ-------PP
360 370 380 390 400
410 420 430
pF1KB7 LTTDDARPLSRLSKASS-RARSDDLTV
: : :. :.::: ::: .::..
NP_068 LPLGDPGRASKASRASSGRARPEDLAI
410 420 430
>>XP_016856533 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 1104 init1: 649 opt: 1032 Z-score: 870.4 bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
XP_016 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
XP_016 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
XP_016 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
XP_016 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
:
XP_016 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>NP_005257 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 1104 init1: 649 opt: 1032 Z-score: 870.4 bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
NP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
NP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
NP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
NP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
:
NP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>XP_005273008 (OMIM: 108770,121013,612474,614049) PREDI (358 aa)
initn: 1104 init1: 649 opt: 1032 Z-score: 870.4 bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
XP_005 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
XP_005 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
XP_005 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
XP_005 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
:
XP_005 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>NP_859054 (OMIM: 108770,121013,612474,614049) gap junc (358 aa)
initn: 1104 init1: 649 opt: 1032 Z-score: 870.4 bits: 169.9 E(85289): 9.6e-42
Smith-Waterman score: 1032; 61.8% identity (83.8% similar) in 241 aa overlap (1-239:1-241)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
:::::::::.::::..::::.:.::::::::::.:.:::::: :::::.:: :.: :::
NP_859 MGDWSFLGNFLEEVHKHSTVVGKVWLTVLFIFRMLVLGTAAESSWGDEQADFRCDTIQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
:.:::::.:::::::: :::::::::::::.:.:::.: :::.:::: ::::. . :.
NP_859 CQNVCYDQAFPISHIRYWVLQIIFVSTPSLVYMGHAMHTVRMQEKRKLREAERAKEVRGS
70 80 90 100 110 120
130 140 150 160 170
pF1KB7 NGG--PDQGSVKKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYFLYGFRIL
.. : ... : .:. .. :.:::: ::.: :...: .:::::::.::.::. .
NP_859 GSYEYPVAEKAELSCWEEGNGRIALQGTLLNTYVCSILIRTTMEVGFIVGQYFIYGIFLT
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB7 PLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKGIRSALKR
:. : : :::. :.:.:::::::..::.:::.::..::.:.. :: ::: : ::. . .
NP_859 TLHVCRRSPCPHPVNCYVSRPTEKNVFIVFMLAVAALSLLLSLAELYHLGWKKIRQRFVK
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB7 PVEQPLGEIPEKSLHSIAVSSIQKAKGYQLLEEEKIVSHYFPLTEVGMVETSPLPAKPFN
:
NP_859 PRQHMAKCQLSGPSVGIVQSCTPPPDFNQCLENGPGGKFFNPFSNNMASQQNTDNLVTEQ
250 260 270 280 290 300
>>NP_115991 (OMIM: 611924) gap junction alpha-10 protein (543 aa)
initn: 973 init1: 557 opt: 955 Z-score: 803.9 bits: 158.2 E(85289): 4.9e-38
Smith-Waterman score: 963; 38.2% identity (66.2% similar) in 456 aa overlap (1-429:1-439)
10 20 30 40 50 60
pF1KB7 MGDWSFLGNILEEVNEHSTVIGRVWLTVLFIFRILILGTAAEFVWGDEQSDFVCNTQQPG
::::..::.:::::. :::..:..:::.:::::.:.: .::: :: :::: :.:::.:::
NP_115 MGDWNLLGGILEEVHSHSTIVGKIWLTILFIFRMLVLRVAAEDVWDDEQSAFACNTRQPG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 CENVCYDEAFPISHIRLWVLQIIFVSTPSLMYVGHAVHYVRMEEKRKSREAEELGQQAGT
:.:.:::.::::: ::.:::::::::.:::.:.:::.. .: :: ..:. .: : .
NP_115 CNNICYDDAFPISLIRFWVLQIIFVSSPSLVYMGHALYRLRAFEKDRQRKKSHLRAQMEN
70 80 90 100 110 120
130 140 150 160 170
pF1KB7 NGGPD-----QGSV----KKSSGSKGTKKFRLEGTLLRTYICHIIFKTLFEVGFIVGHYF
:: : . .. .: .: :.: :::::. ::. ....::::..:.:.
NP_115 ---PDLDLEEQQRIDRELRRLEEQKRIHKVPLKGCLLRTYVLHILTRSVLEVGFMIGQYI
130 140 150 160 170
180 190 200 210 220 230
pF1KB7 LYGFRILPLYRCSRWPCPNVVDCFVSRPTEKTIFILFMLSVASVSLFLNVMELGHLGLKG
::::.. :::.:.. ::::.::::::::::::::.::: :.:..::.::..:. :::..
NP_115 LYGFQMHPLYKCTQPPCPNAVDCFVSRPTEKTIFMLFMHSIAAISLLLNILEIFHLGIRK
180 190 200 210 220 230
240 250 260 270 280
pF1KB7 I-RSALKRP----VEQPLGEIPEKSLHSIA-----VSSI-QKAKGYQLLEEEKIVSHYFP
: :. :. .:. : . . .:.: ::. .. . : ...... :
NP_115 IMRTLYKKSSSEGIEDETGPPFHLKKYSVAQQCMICSSLPERISPLQANNQQQVIRVNVP
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB7 LTEVGMVETSPLPAKPFNQFEEKISTGPLGDLSRGYQETLPSYAQVGAQEVEGEGPPAEE
... : . : : :.: :.: : :. :.. : .:.. : :
NP_115 KSKT-MWQI-PQP----RQLEVDPSNGK-KDWSEKDQHS-------GQLHVHSPCPWAGS
300 310 320 330 340
350 360 370 380 390
pF1KB7 GAEPEVGEKKEEA-----ERLTTEEQEKVAVPEGEKVETPGVDKEGEKEEPQSEKVSKQG
... ..:...... . .. ...:.. . :. .... ::..: ..
NP_115 AGNQHLGQQSDHSSFGLQNTMSQSWLGTTTAPRNCPSFAVGTWEQSQDPEPSGEPLTDLH
350 360 370 380 390 400
400 410 420 430
pF1KB7 LPAEKTPSLCPE--LTTDDARPLSRLSKASSRARSDDLTV
. . . : . : .:: :: .. :: :.
NP_115 SHCRDSEGSMRESGVWIDRSRPGSRKASFLSRLLSEKRHLHSDSGSSGSRNSSCLDFPHW
410 420 430 440 450 460
NP_115 ENSPSPLPSVTGHRTSMVRQAALPIMELSQELFHSGCFLFPFFLPGVCMYVCVDREADGG
470 480 490 500 510 520
433 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 05:34:54 2016 done: Fri Nov 4 05:34:56 2016
Total Scan time: 10.120 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]