Result of FASTA (omim) for
pFN21AB5484
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5484, 650 aa
1>>>pF1KB5484 650 - 650 aa - 650 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6982+/-0.000305; mu= 10.7909+/- 0.019
mean_var=171.6354+/-34.263, 0's: 0 Z-trim(122.9): 23 B-trim: 532 in 1/55
Lambda= 0.097897
statistics sampled from 41896 (41919) to 41896 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.8), E-opt: 0.2 (0.491), width: 16
Scan time: 13.880
The best scores are: opt bits E(85289)
NP_005157 (OMIM: 104775) amyloid-like protein 1 is ( 650) 4446 639.9 8.4e-183
NP_001019978 (OMIM: 104775) amyloid-like protein 1 ( 651) 4434 638.2 2.7e-182
XP_016882227 (OMIM: 104775) PREDICTED: amyloid-lik ( 597) 2522 368.1 5e-101
XP_016882226 (OMIM: 104775) PREDICTED: amyloid-lik ( 598) 2522 368.1 5e-101
NP_001315611 (OMIM: 104776) amyloid-like protein 2 ( 707) 801 125.1 8.4e-28
NP_001135749 (OMIM: 104776) amyloid-like protein 2 ( 695) 798 124.7 1.1e-27
NP_001315614 (OMIM: 104776) amyloid-like protein 2 ( 644) 779 122.0 6.7e-27
NP_001135750 (OMIM: 104776) amyloid-like protein 2 ( 522) 762 119.5 3e-26
NP_001315615 (OMIM: 104776) amyloid-like protein 2 ( 730) 764 119.9 3.2e-26
NP_001633 (OMIM: 104776) amyloid-like protein 2 is ( 763) 764 119.9 3.3e-26
NP_001135748 (OMIM: 104776) amyloid-like protein 2 ( 751) 761 119.5 4.4e-26
NP_001230228 (OMIM: 104776) amyloid-like protein 2 ( 761) 761 119.5 4.4e-26
NP_001315613 (OMIM: 104776) amyloid-like protein 2 ( 700) 742 116.8 2.7e-25
NP_001129601 (OMIM: 104300,104760,605714) amyloid ( 639) 719 113.5 2.4e-24
NP_001129603 (OMIM: 104300,104760,605714) amyloid ( 660) 719 113.5 2.4e-24
NP_001191232 (OMIM: 104300,104760,605714) amyloid ( 677) 719 113.5 2.5e-24
NP_958817 (OMIM: 104300,104760,605714) amyloid bet ( 695) 719 113.6 2.5e-24
NP_001191231 (OMIM: 104300,104760,605714) amyloid ( 733) 702 111.2 1.4e-23
NP_001129488 (OMIM: 104300,104760,605714) amyloid ( 746) 702 111.2 1.4e-23
NP_958816 (OMIM: 104300,104760,605714) amyloid bet ( 751) 702 111.2 1.4e-23
NP_001129602 (OMIM: 104300,104760,605714) amyloid ( 714) 683 108.5 8.8e-23
NP_001191230 (OMIM: 104300,104760,605714) amyloid ( 752) 683 108.5 9.1e-23
NP_000475 (OMIM: 104300,104760,605714) amyloid bet ( 770) 683 108.5 9.3e-23
>>NP_005157 (OMIM: 104775) amyloid-like protein 1 isofor (650 aa)
initn: 4446 init1: 4446 opt: 4446 Z-score: 3402.9 bits: 639.9 E(85289): 8.4e-183
Smith-Waterman score: 4446; 100.0% identity (100.0% similar) in 650 aa overlap (1-650:1-650)
10 20 30 40 50 60
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB5 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKM
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB5 NPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSM
550 560 570 580 590 600
610 620 630 640 650
pF1KB5 LLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
610 620 630 640 650
>>NP_001019978 (OMIM: 104775) amyloid-like protein 1 iso (651 aa)
initn: 3573 init1: 3573 opt: 4434 Z-score: 3393.7 bits: 638.2 E(85289): 2.7e-182
Smith-Waterman score: 4434; 99.8% identity (99.8% similar) in 651 aa overlap (1-650:1-651)
10 20 30 40 50 60
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB5 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB5 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
430 440 450 460 470 480
490 500 510 520 530
pF1KB5 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKD-DTPMTLPKGSTEQDAASPEKEK
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
NP_001 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEK
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB5 MNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLS
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB5 MLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
610 620 630 640 650
>>XP_016882227 (OMIM: 104775) PREDICTED: amyloid-like pr (597 aa)
initn: 2491 init1: 2491 opt: 2522 Z-score: 1934.8 bits: 368.1 E(85289): 5e-101
Smith-Waterman score: 3996; 91.8% identity (91.8% similar) in 650 aa overlap (1-650:1-597)
10 20 30 40 50 60
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNE--------
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
:::::::::::::::
XP_016 ---------------------------------------------AERVLLALRRYLRAE
360
430 440 450 460 470 480
pF1KB5 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
370 380 390 400 410 420
490 500 510 520 530 540
pF1KB5 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKM
430 440 450 460 470 480
550 560 570 580 590 600
pF1KB5 NPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLSM
490 500 510 520 530 540
610 620 630 640 650
pF1KB5 LLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
550 560 570 580 590
>>XP_016882226 (OMIM: 104775) PREDICTED: amyloid-like pr (598 aa)
initn: 3357 init1: 2492 opt: 2522 Z-score: 1934.8 bits: 368.1 E(85289): 5e-101
Smith-Waterman score: 3984; 91.7% identity (91.7% similar) in 651 aa overlap (1-650:1-598)
10 20 30 40 50 60
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPGSRVEGA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGVDIYFGM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNE--------
310 320 330 340 350
370 380 390 400 410 420
pF1KB5 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
:::::::::::::::
XP_016 ---------------------------------------------AERVLLALRRYLRAE
360
430 440 450 460 470 480
pF1KB5 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
370 380 390 400 410 420
490 500 510 520 530
pF1KB5 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKD-DTPMTLPKGSTEQDAASPEKEK
::::::::::::::::::::::::::::::::::::: ::::::::::::::::::::::
XP_016 IQELLHSEHLGPSELEAPAPGGSSEDKGGLQPPDSKDADTPMTLPKGSTEQDAASPEKEK
430 440 450 460 470 480
540 550 560 570 580 590
pF1KB5 MNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNPLEQYERKVNASVPRGFPFHSSEIQRDELAPAGTGVSREAVSGLLIMGAGGGSLIVLS
490 500 510 520 530 540
600 610 620 630 640 650
pF1KB5 MLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
550 560 570 580 590
>>NP_001315611 (OMIM: 104776) amyloid-like protein 2 iso (707 aa)
initn: 1612 init1: 768 opt: 801 Z-score: 620.2 bits: 125.1 E(85289): 8.4e-28
Smith-Waterman score: 1603; 40.5% identity (68.8% similar) in 696 aa overlap (23-648:15-704)
10 20 30 40 50
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSA
:: :::. : : ::. .::: .. :.. : .
NP_001 MAATGTAAAAATGRLLLLLLVGLTA-PAL-ALAGYIEALAANAGTGFAVAEP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAI
:.: .::.:..: ...::.::::: .. :.. ..::.::..:::::::. : .:.: .
NP_001 QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRH
.. :: ... .: . :.::.:: :::::..::::: :.:.:.:::. ::. . :
NP_001 SIDNWCRRDKK-QCK--SRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWH
120 130 140 150 160
180 190 200 210 220
pF1KB5 QEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPP---GT-------PDPSGTAVG
..::: .::. :.. ::::::: :.:.:.:::::: :. :
NP_001 TVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEE
170 180 190 200 210 220
230 240 250 260 270
pF1KB5 D------------PSTRSWPPGSRVEGAEDEEEEESFPQPVDD--YFVEPPQAEEEEETV
: :. . ... ::.:.:: . :.: :. . .... .:
NP_001 DEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEEN
230 240 250 260 270 280
280 290 300 310 320
pF1KB5 P--PPSSHTLA---VVG--KVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMR
: : :. :.. .. :: ::: ::. ::.:: .. .:: : .:: .:: :.
NP_001 PTEPGSDGTMSDKEITHDVKVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRN
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 QINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIAL
....: .:: :. :.::::::.::.: .:::.....::.....:.:.::::: .:: :.
NP_001 RMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAM
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB5 INDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQ
.::.:: :::..:::::.:::. .:.: :::::.:::.:.. ::.:::::: :::::::
NP_001 LNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAA
410 420 430 440 450 460
450 460 470 480 490 500
pF1KB5 QMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAP---AP
::. :: :::.::::: ::::.:: . :..:::.. .:.:::. .. ... : .:
NP_001 QMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETP
470 480 490 500 510 520
510 520 530 540
pF1KB5 GG---SSEDKGGLQP----------PDSKDDTP---MTLPKGST--EQDAA--SPEKEKM
:::.. . : :...: : . ::: :::.. . :.. .
NP_001 VDVRVSSEESEEIPPFHPFHPFPALPENEDTQPELYHPMKKGSGVGEQDGGLIGAEEKVI
530 540 550 560 570 580
550 560 570 580 590
pF1KB5 NPLEQYERK--VNASVP-RGFPFHSSEI-----QRDELAP--AGTGVSREAVSGLLIMGA
: .. ... .. .. . . :.. .. .:. ..: ..: :. :::....
NP_001 NSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAV
590 600 610 620 630 640
600 610 620 630 640 650
pF1KB5 GGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
. ...::.:...:: :. ::.::::.:::::::: ::..: ..: ::::::::..::.
NP_001 AIATVIVISLVMLR-KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQ
650 660 670 680 690 700
NP_001 I
>>NP_001135749 (OMIM: 104776) amyloid-like protein 2 iso (695 aa)
initn: 1612 init1: 768 opt: 798 Z-score: 618.0 bits: 124.7 E(85289): 1.1e-27
Smith-Waterman score: 1602; 40.6% identity (69.3% similar) in 684 aa overlap (23-648:15-692)
10 20 30 40 50
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSA
:: :::. : : ::. .::: .. :.. : .
NP_001 MAATGTAAAAATGRLLLLLLVGLTA-PAL-ALAGYIEALAANAGTGFAVAEP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAI
:.: .::.:..: ...::.::::: .. :.. ..::.::..:::::::. : .:.: .
NP_001 QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRH
.. :: ... .: . :.::.:: :::::..::::: :.:.:.:::. ::. . :
NP_001 SIDNWCRRDKK-QCK--SRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWH
120 130 140 150 160
180 190 200 210 220
pF1KB5 QEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPP---GT-------PDPSGTAVG
..::: .::. :.. ::::::: :.:.:.:::::: :. :
NP_001 TVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEE
170 180 190 200 210 220
230 240 250 260 270
pF1KB5 D------------PSTRSWPPGSRVEGAEDEEEEESFPQPVDD--YFVEPPQAEEEEETV
: :. . ... ::.:.:: . :.: :. . .... .:
NP_001 DEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEEN
230 240 250 260 270 280
280 290 300 310 320
pF1KB5 P--PPSSHTLA---VVG--KVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMR
: : :. :.. .. :: ::: ::. ::.:: .. .:: : .:: .:: :.
NP_001 PTEPGSDGTMSDKEITHDVKVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRN
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 QINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIAL
....: .:: :. :.::::::.::.: .:::.....::.....:.:.::::: .:: :.
NP_001 RMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAM
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB5 INDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQ
.::.:: :::..:::::.:::. .:.: :::::.:::.:.. ::.:::::: :::::::
NP_001 LNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAA
410 420 430 440 450 460
450 460 470 480 490
pF1KB5 QMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSEL-----EAP
::. :: :::.::::: ::::.:: . :..:::.. .:.:::. .. ... :.:
NP_001 QMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEEIDELLQEQRADMDQFTASISETP
470 480 490 500 510 520
500 510 520 530 540 550
pF1KB5 APGGSSEDKGGLQPPDSKDDTPMTLPK----GSTEQDAA--SPEKEKMNPLEQYERK--V
. : ... :: .::. : :::.. . :.. .: .. ... .
NP_001 VDVRVSSEESEEIPPFHPFHPFPALPENEGSGVGEQDGGLIGAEEKVINSKNKVDENMVI
530 540 550 560 570 580
560 570 580 590 600
pF1KB5 NASVP-RGFPFHSSEI-----QRDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLL
. .. . . :.. .. .:. ..: ..: :. :::..... ...::.:...
NP_001 DETLDVKEMIFNAERVGGLEEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVM
590 600 610 620 630 640
610 620 630 640 650
pF1KB5 LRRKKPYGAISHGVVEVDPMLTLEEQQLRELQRHGYENPTYRFLEERP
:: :. ::.::::.:::::::: ::..: ..: ::::::::..::.
NP_001 LR-KRQYGTISHGIVEVDPMLTPEERHLNKMQNHGYENPTYKYLEQMQI
650 660 670 680 690
>>NP_001315614 (OMIM: 104776) amyloid-like protein 2 iso (644 aa)
initn: 1387 init1: 749 opt: 779 Z-score: 603.9 bits: 122.0 E(85289): 6.7e-27
Smith-Waterman score: 1564; 41.8% identity (67.7% similar) in 665 aa overlap (23-648:15-641)
10 20 30 40 50
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSA
:: :::. : : ::. .::: .. :.. : .
NP_001 MAATGTAAAAATGRLLLLLLVGLTA-PAL-ALAGYIEALAANAGTGFAVAEP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAI
:.: .::.:..: ...::.::::: .. :.. ..::.::..:::::::. : .:.: .
NP_001 QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRH
.. :: ... .: . :.::.:: :::::..::::: :.:.:.:::. ::. . :
NP_001 SIDNWCRRDKK-QCK--SRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWH
120 130 140 150 160
180 190 200 210 220
pF1KB5 QEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPP---GT-------PDPSGTAVG
..::: .::. :.. ::::::: :.:.:.:::::: :. :
NP_001 TVVKEACLTQGMTLYSYGMLLPCGVDQFHGTEYVCCPQTKIIGSVSKEEEEEDEEEEEEE
170 180 190 200 210 220
230 240 250 260 270
pF1KB5 D------------PSTRSWPPGSRVEGAEDEEEEESFPQPVDD--YFVEPPQAEEEEETV
: :. . ... ::.:.:: . :.: :. . .... .:
NP_001 DEEEDYDVYKSEFPTEADLEDFTEAAVDEDDEDEEEGEEVVEDRDYYYDTFKGDDYNEEN
230 240 250 260 270 280
280 290 300 310 320
pF1KB5 P--PPSSHTLA---VVG--KVTPTPRPTDGVDIYFGMPGEISEHEGFLRAKMDLEERRMR
: : :. :.. .. :: ::: ::. ::.:: .. .:: : .:: .:: :.
NP_001 PTEPGSDGTMSDKEITHDVKVPPTPLPTNDVDVYFETSADDNEHARFQKAKEQLEIRHRN
290 300 310 320 330 340
330 340 350 360 370 380
pF1KB5 QINEVMREWAMADNQSKNLPKADRQALNEHFQSILQTLEEQVSGERQRLVETHATRVIAL
....: .:: :. :.::::::.::.: .:::.....::.....:.:.::::: .:: :.
NP_001 RMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKALEKEAASEKQQLVETHLARVEAM
350 360 370 380 390 400
390 400 410 420 430 440
pF1KB5 INDQRRAALEGFLAALQADPPQAERVLLALRRYLRAEQKEQRHTLRHYQHVAAVDPEKAQ
.::.:: :::..:::::.:::. .:.: :::::.:::.:.. ::.:::::: :::::::
NP_001 LNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAENKDRLHTIRHYQHVLAVDPEKAA
410 420 430 440 450 460
450 460 470 480 490 500
pF1KB5 QMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQIQELLHSEHLGPSELEAPAPGGS
::. :: :::.::::: ::::.:: . :..::: ::: . : :
NP_001 QMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQE----IQEEIGS--------------GV
470 480 490 500
510 520 530 540 550 560
pF1KB5 SEDKGGLQPPDSKDDTPMTLPKGSTEQDAASPEKEKMNPLEQYERKVNASVPRGFPFHSS
.:. ::: . : . :...... . : :. : :: :.
NP_001 GEQDGGLIGAEEK----VINSKNKVDENMVIDET-----LDVKEMIFNAERVGGL-----
510 520 530 540 550
570 580 590 600 610 620
pF1KB5 EIQRDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDP
: .:. ..: ..: :. :::..... ...::.:...:: :. ::.::::.:::::
NP_001 EEERESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR-KRQYGTISHGIVEVDP
560 570 580 590 600 610
630 640 650
pF1KB5 MLTLEEQQLRELQRHGYENPTYRFLEERP
::: ::..: ..: ::::::::..::.
NP_001 MLTPEERHLNKMQNHGYENPTYKYLEQMQI
620 630 640
>>NP_001135750 (OMIM: 104776) amyloid-like protein 2 iso (522 aa)
initn: 1253 init1: 762 opt: 762 Z-score: 592.2 bits: 119.5 E(85289): 3e-26
Smith-Waterman score: 1023; 33.7% identity (57.7% similar) in 653 aa overlap (23-648:15-519)
10 20 30 40 50
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSA
:: :::. : : ::. .::: .. :.. : .
NP_001 MAATGTAAAAATGRLLLLLLVGLTA-PAL-ALAGYIEALAANAGTGFAVAEP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAI
:.: .::.:..: ...::.::::: .. :.. ..::.::..:::::::. : .:.: .
NP_001 QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRH
.. :: ... .: . :.::.:: ::
NP_001 SIDNWCRRDKK-QCKS--RFVTPFKCL----------VP---------------------
120 130
180 190 200 210 220 230
pF1KB5 QEAQEACSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSGTAVGDPSTRSWPPG
NP_001 ------------------------------------------------------------
240 250 260 270 280 290
pF1KB5 SRVEGAEDEEEEESFPQPVDDYFVEPPQAEEEEETVPPPSSHTLAVVGKVTPTPRPTDGV
::: ::. :
NP_001 ---------------------------------------------------PTPLPTNDV
140
300 310 320 330 340 350
pF1KB5 DIYFGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHF
:.:: .. .:: : .:: .:: :. ....: .:: :. :.::::::.::.: .::
NP_001 DVYFETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHF
150 160 170 180 190 200
360 370 380 390 400 410
pF1KB5 QSILQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALR
:.....::.....:.:.::::: .:: :..::.:: :::..:::::.:::. .:.: :::
NP_001 QAMVKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALR
210 220 230 240 250 260
420 430 440 450 460 470
pF1KB5 RYLRAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLA
::.:::.:.. ::.:::::: ::::::: ::. :: :::.::::: ::::.:: . :..:
NP_001 RYVRAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVA
270 280 290 300 310 320
480 490 500 510 520
pF1KB5 QELRPQIQELLHSEHLGPSEL-----EAPAPGGSSEDKGGLQPPDSKDDTPMTLPK----
::.. .:.:::. .. ... :.:. : ... :: .::.
NP_001 QEIQEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEGS
330 340 350 360 370 380
530 540 550 560 570
pF1KB5 GSTEQDAA--SPEKEKMNPLEQYERK--VNASVP-RGFPFHSSEI-----QRDELAP--A
: :::.. . :.. .: .. ... .. .. . . :.. .. .:. ..:
NP_001 GVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERESVGPLRE
390 400 410 420 430 440
580 590 600 610 620 630
pF1KB5 GTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEEQQLREL
..: :. :::..... ...::.:...:: :. ::.::::.:::::::: ::..: ..
NP_001 DFSLSSSALIGLLVIAVAIATVIVISLVMLR-KRQYGTISHGIVEVDPMLTPEERHLNKM
450 460 470 480 490 500
640 650
pF1KB5 QRHGYENPTYRFLEERP
: ::::::::..::.
NP_001 QNHGYENPTYKYLEQMQI
510 520
>>NP_001315615 (OMIM: 104776) amyloid-like protein 2 iso (730 aa)
initn: 1418 init1: 761 opt: 764 Z-score: 591.7 bits: 119.9 E(85289): 3.2e-26
Smith-Waterman score: 1321; 35.9% identity (63.7% similar) in 716 aa overlap (26-648:17-727)
10 20 30 40 50
pF1KB5 MGPASPAARGLSRRPGQPPLPLLLPLLLLLLRAQPAIGSLAG------GSPGAAEAPGSA
::::. . ::. .::: .. :.. : .
NP_001 MAATGTAAAAATGRLLLLLLVGLTAPAL-ALAGYIEALAANAGTGFAVAEP
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 QVAGLCGRLTLHRDLRTGRWEPDPQRSRRCLRDPQRVLEYCRQMYPELQIARVEQATQAI
:.: .::.:..: ...::.::::: .. :.. ..::.::..:::::::. : .:.: .
NP_001 QIAMFCGKLNMHVNIQTGKWEPDPTGTKSCFETKEEVLQYCQEMYPELQITNVMEANQRV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 PMERWCGGSRSGSCAHPHHQVVPFRCLPGEFVSEALLVPEGCRFLHQERMDQCESSTRRH
.. :: ... .: . :.::.:: :::::..::::: :.:.:.:::. ::. . :
NP_001 SIDNWCRRDKK-QCK--SRFVTPFKCLVGEFVSDVLLVPEKCQFFHKERMEVCENHQHWH
120 130 140 150 160
180 190 200 210 220 230
pF1KB5 QEAQEA--CSSQGLILHGSGMLLPCGSDRFRGVEYVCCPPPGTPDPSG--TAVGDPSTRS
..:. .: . . :. . . : : :. : . ..
NP_001 TVVKETKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDEDDED
170 180 190 200 210 220
240 250 260 270
pF1KB5 WPPGSRV-EGAE--------DEEEEESFPQPVDDYFVEPPQAEEE------EETVPPPS-
: .: : . :. .::. .: .: . . .. .:.. :
NP_001 EEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTGPCR
230 240 250 260 270 280
280 290 300
pF1KB5 ---------------------------------SHTLAVV-GKVTPTPRPTDGVDIYFGM
.. .:: . . ::: ::. ::.::
NP_001 AVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTNDVDVYFET
290 300 310 320 330 340
310 320 330 340 350 360
pF1KB5 PGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSILQT
.. .:: : .:: .:: :. ....: .:: :. :.::::::.::.: .:::.....
NP_001 SADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAMVKA
350 360 370 380 390 400
370 380 390 400 410 420
pF1KB5 LEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYLRAE
::.....:.:.::::: .:: :..::.:: :::..:::::.:::. .:.: :::::.:::
NP_001 LEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYVRAE
410 420 430 440 450 460
430 440 450 460 470 480
pF1KB5 QKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQELRPQ
.:.. ::.:::::: ::::::: ::. :: :::.::::: ::::.:: . :..:::.. .
NP_001 NKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEIQEE
470 480 490 500 510 520
490 500 510 520
pF1KB5 IQELLHSEHLGPSELEAP---APGG---SSEDKGGLQP----------PDSKDDTP---M
:.:::. .. ... : .: :::.. . : :...: :
NP_001 IDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEDTQPELYH
530 540 550 560 570 580
530 540 550 560
pF1KB5 TLPKGST--EQDAA--SPEKEKMNPLEQYERK--VNASVP-RGFPFHSSEI-----QRDE
. ::: :::.. . :.. .: .. ... .. .. . . :.. .. .:.
NP_001 PMKKGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEERES
590 600 610 620 630 640
570 580 590 600 610 620
pF1KB5 LAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLTLEE
..: ..: :. :::..... ...::.:...:: :. ::.::::.:::::::: ::
NP_001 VGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR-KRQYGTISHGIVEVDPMLTPEE
650 660 670 680 690 700
630 640 650
pF1KB5 QQLRELQRHGYENPTYRFLEERP
..: ..: ::::::::..::.
NP_001 RHLNKMQNHGYENPTYKYLEQMQI
710 720 730
>>NP_001633 (OMIM: 104776) amyloid-like protein 2 isofor (763 aa)
initn: 1605 init1: 761 opt: 764 Z-score: 591.5 bits: 119.9 E(85289): 3.3e-26
Smith-Waterman score: 1474; 37.8% identity (64.0% similar) in 714 aa overlap (55-648:51-760)
30 40 50 60 70 80
pF1KB5 PLLLLLLRAQPAIGSLAGGSPGAAEAPGSAQVAGLCGRLTLHRDLRTGRWEPDPQRSRRC
:.: .::.:..: ...::.::::: .. :
NP_001 VGLTAPALALAGYIEALAANAGTGFAVAEPQIAMFCGKLNMHVNIQTGKWEPDPTGTKSC
30 40 50 60 70 80
90 100 110 120 130 140
pF1KB5 LRDPQRVLEYCRQMYPELQIARVEQATQAIPMERWCGGSRSGSCAHPHHQVVPFRCLPGE
.. ..::.::..:::::::. : .:.: . .. :: ... .: :.::.:: ::
NP_001 FETKEEVLQYCQEMYPELQITNVMEANQRVSIDNWCRRDKK-QCKSRF--VTPFKCLVGE
90 100 110 120 130
150 160 170 180 190 200
pF1KB5 FVSEALLVPEGCRFLHQERMDQCESSTRRHQEAQEACSSQGLILHGSGMLLPCGSDRFRG
:::..::::: :.:.:.:::. ::. . : ..::: .::. :.. ::::::: :.:.:
NP_001 FVSDVLLVPEKCQFFHKERMEVCENHQHWHTVVKEACLTQGMTLYSYGMLLPCGVDQFHG
140 150 160 170 180 190
210 220 230 240
pF1KB5 VEYVCCPPP---GT-------------PDPSGTAVGDPSTRSWPPGSRVEG------AED
.:::::: :. . . : .: . .: ::
NP_001 TEYVCCPQTKIIGSVSKEEEEEDEEEEEEEDEEEDYDVYKSEFPTEADLEDFTEAAVDED
200 210 220 230 240 250
250 260 270
pF1KB5 EEEEESFPQPVDD--YFVEPPQAEEEEETVP--PPSSHTL--------------------
.:.:: . :.: :. . .... .: : : :. :.
NP_001 DEDEEEGEEVVEDRDYYYDTFKGDDYNEENPTEPGSDGTMSDKEITHDVKAVCSQEAMTG
260 270 280 290 300 310
280 290
pF1KB5 ---AVV---------GK-----------------------------VTPTPRPTDGVDIY
::. :: . ::: ::. ::.:
NP_001 PCRAVMPRWYFDLSKGKCVRFIYGGCGGNRNNFESEDYCMAVCKAMIPPTPLPTNDVDVY
320 330 340 350 360 370
300 310 320 330 340 350
pF1KB5 FGMPGEISEHEGFLRAKMDLEERRMRQINEVMREWAMADNQSKNLPKADRQALNEHFQSI
: .. .:: : .:: .:: :. ....: .:: :. :.::::::.::.: .:::..
NP_001 FETSADDNEHARFQKAKEQLEIRHRNRMDRVKKEWEEAELQAKNLPKAERQTLIQHFQAM
380 390 400 410 420 430
360 370 380 390 400 410
pF1KB5 LQTLEEQVSGERQRLVETHATRVIALINDQRRAALEGFLAALQADPPQAERVLLALRRYL
...::.....:.:.::::: .:: :..::.:: :::..:::::.:::. .:.: :::::.
NP_001 VKALEKEAASEKQQLVETHLARVEAMLNDRRRMALENYLAALQSDPPRPHRILQALRRYV
440 450 460 470 480 490
420 430 440 450 460 470
pF1KB5 RAEQKEQRHTLRHYQHVAAVDPEKAQQMRFQVHTHLQVIEERVNQSLGLLDQNPHLAQEL
:::.:.. ::.:::::: ::::::: ::. :: :::.::::: ::::.:: . :..:::.
NP_001 RAENKDRLHTIRHYQHVLAVDPEKAAQMKSQVMTHLHVIEERRNQSLSLLYKVPYVAQEI
500 510 520 530 540 550
480 490 500 510 520
pF1KB5 RPQIQELLHSEHLGPSELEAP---APGG---SSEDKGGLQP----------PDSKDDTP-
. .:.:::. .. ... : .: :::.. . : :...: :
NP_001 QEEIDELLQEQRADMDQFTASISETPVDVRVSSEESEEIPPFHPFHPFPALPENEDTQPE
560 570 580 590 600 610
530 540 550 560
pF1KB5 --MTLPKGST--EQDAA--SPEKEKMNPLEQYERK--VNASVP-RGFPFHSSEI-----Q
. ::: :::.. . :.. .: .. ... .. .. . . :.. .. .
NP_001 LYHPMKKGSGVGEQDGGLIGAEEKVINSKNKVDENMVIDETLDVKEMIFNAERVGGLEEE
620 630 640 650 660 670
570 580 590 600 610 620
pF1KB5 RDELAP--AGTGVSREAVSGLLIMGAGGGSLIVLSMLLLRRKKPYGAISHGVVEVDPMLT
:. ..: ..: :. :::..... ...::.:...:: :. ::.::::.::::::::
NP_001 RESVGPLREDFSLSSSALIGLLVIAVAIATVIVISLVMLR-KRQYGTISHGIVEVDPMLT
680 690 700 710 720 730
630 640 650
pF1KB5 LEEQQLRELQRHGYENPTYRFLEERP
::..: ..: ::::::::..::.
NP_001 PEERHLNKMQNHGYENPTYKYLEQMQI
740 750 760
650 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:49:17 2016 done: Fri Nov 4 03:49:19 2016
Total Scan time: 13.880 Total Display time: 0.150
Function used was FASTA [36.3.4 Apr, 2011]