Result of FASTA (omim) for
pFN21AB4976
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4976, 418 aa
1>>>pF1KB4976 418 - 418 aa - 418 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4552+/-0.000303; mu= 17.3673+/- 0.019
mean_var=78.2214+/-15.661, 0's: 0 Z-trim(117.4): 28 B-trim: 49 in 3/54
Lambda= 0.145014
statistics sampled from 29281 (29310) to 29281 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.709), E-opt: 0.2 (0.344), width: 16
Scan time: 8.540
The best scores are: opt bits E(85289)
NP_004032 (OMIM: 107940) beta-arrestin-1 isoform A ( 418) 2776 590.0 3.6e-168
XP_011543336 (OMIM: 107940) PREDICTED: beta-arrest ( 449) 2736 581.7 1.3e-165
NP_064647 (OMIM: 107940) beta-arrestin-1 isoform B ( 410) 2704 575.0 1.2e-163
XP_011543337 (OMIM: 107940) PREDICTED: beta-arrest ( 441) 2664 566.6 4.2e-161
XP_016873241 (OMIM: 107940) PREDICTED: beta-arrest ( 442) 2532 539.0 8.7e-153
XP_016873239 (OMIM: 107940) PREDICTED: beta-arrest ( 473) 2492 530.7 3e-150
XP_016873242 (OMIM: 107940) PREDICTED: beta-arrest ( 437) 2483 528.8 1.1e-149
XP_016873243 (OMIM: 107940) PREDICTED: beta-arrest ( 434) 2460 523.9 2.9e-148
XP_016873240 (OMIM: 107940) PREDICTED: beta-arrest ( 465) 2420 515.6 1e-145
NP_004304 (OMIM: 107941) beta-arrestin-2 isoform 1 ( 409) 2150 459.1 9.4e-129
XP_011522160 (OMIM: 107941) PREDICTED: beta-arrest ( 440) 2126 454.1 3.2e-127
NP_001244259 (OMIM: 107941) beta-arrestin-2 isofor ( 421) 2005 428.7 1.3e-119
NP_945355 (OMIM: 107941) beta-arrestin-2 isoform 2 ( 394) 1865 399.4 8.1e-111
NP_001244260 (OMIM: 107941) beta-arrestin-2 isofor ( 406) 1720 369.1 1.1e-101
NP_004303 (OMIM: 301770) arrestin-C [Homo sapiens] ( 388) 1545 332.5 1.1e-90
NP_001244257 (OMIM: 107941) beta-arrestin-2 isofor ( 430) 1514 326.0 1.1e-88
NP_001244258 (OMIM: 107941) beta-arrestin-2 isofor ( 330) 1479 318.6 1.4e-86
NP_000532 (OMIM: 181031,258100,613758) S-arrestin ( 405) 1475 317.8 3e-86
XP_016860131 (OMIM: 181031,258100,613758) PREDICTE ( 369) 1473 317.4 3.7e-86
XP_016860130 (OMIM: 181031,258100,613758) PREDICTE ( 373) 1473 317.4 3.8e-86
XP_016885007 (OMIM: 301770) PREDICTED: arrestin-C ( 403) 1374 296.7 6.9e-80
NP_001316993 (OMIM: 107941) beta-arrestin-2 isofor ( 217) 1064 231.7 1.4e-60
XP_016860132 (OMIM: 181031,258100,613758) PREDICTE ( 273) 1047 228.2 2e-59
XP_011509895 (OMIM: 181031,258100,613758) PREDICTE ( 305) 1025 223.6 5.3e-58
XP_011509896 (OMIM: 181031,258100,613758) PREDICTE ( 281) 1017 221.9 1.6e-57
XP_011509898 (OMIM: 181031,258100,613758) PREDICTE ( 271) 973 212.7 9e-55
XP_016880134 (OMIM: 107941) PREDICTED: beta-arrest ( 229) 919 201.4 2e-51
>>NP_004032 (OMIM: 107940) beta-arrestin-1 isoform A [Ho (418 aa)
initn: 2776 init1: 2776 opt: 2776 Z-score: 3140.2 bits: 590.0 E(85289): 3.6e-168
Smith-Waterman score: 2776; 100.0% identity (100.0% similar) in 418 aa overlap (1-418:1-418)
10 20 30 40 50 60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
310 320 330 340 350 360
370 380 390 400 410
pF1KB4 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
370 380 390 400 410
>>XP_011543336 (OMIM: 107940) PREDICTED: beta-arrestin-1 (449 aa)
initn: 2736 init1: 2736 opt: 2736 Z-score: 3094.5 bits: 581.7 E(85289): 1.3e-165
Smith-Waterman score: 2736; 99.8% identity (100.0% similar) in 413 aa overlap (6-418:37-449)
10 20 30
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
.:::::::::::::::::::::::::::::
XP_011 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
370 380 390 400 410 420
400 410
pF1KB4 LKGMKDDKEEEEDGTGSPQLNNR
:::::::::::::::::::::::
XP_011 LKGMKDDKEEEEDGTGSPQLNNR
430 440
>>NP_064647 (OMIM: 107940) beta-arrestin-1 isoform B [Ho (410 aa)
initn: 2716 init1: 2204 opt: 2704 Z-score: 3058.9 bits: 575.0 E(85289): 1.2e-163
Smith-Waterman score: 2704; 98.1% identity (98.1% similar) in 418 aa overlap (1-418:1-410)
10 20 30 40 50 60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
::::::::::::::::::::::::::::::::: :::::::::::::::::::
NP_064 ASSTLLREGANREILGIIVSYKVKVKLVVSRGG--------DVAVELPFTLMHPKPKEEP
310 320 330 340 350
370 380 390 400 410
pF1KB4 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_064 PHREVPENETPVDTNLIELDTNDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
360 370 380 390 400 410
>>XP_011543337 (OMIM: 107940) PREDICTED: beta-arrestin-1 (441 aa)
initn: 2676 init1: 2164 opt: 2664 Z-score: 3013.2 bits: 566.6 E(85289): 4.2e-161
Smith-Waterman score: 2664; 97.8% identity (98.1% similar) in 413 aa overlap (6-418:37-441)
10 20 30
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
.:::::::::::::::::::::::::::::
XP_011 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGG--
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ------DVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNDDDIVFEDFARQR
370 380 390 400 410
400 410
pF1KB4 LKGMKDDKEEEEDGTGSPQLNNR
:::::::::::::::::::::::
XP_011 LKGMKDDKEEEEDGTGSPQLNNR
420 430 440
>>XP_016873241 (OMIM: 107940) PREDICTED: beta-arrestin-1 (442 aa)
initn: 2532 init1: 2532 opt: 2532 Z-score: 2864.0 bits: 539.0 E(85289): 8.7e-153
Smith-Waterman score: 2718; 94.6% identity (94.6% similar) in 442 aa overlap (1-418:1-442)
10 20 30 40 50 60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
310 320 330 340 350 360
370 380 390
pF1KB4 PHREVPENETPVDTNLIELDTN------------------------DDDIVFEDFARQRL
:::::::::::::::::::::: ::::::::::::::
XP_016 PHREVPENETPVDTNLIELDTNQRPSSHRTVARGGGPGPTARTASSDDDIVFEDFARQRL
370 380 390 400 410 420
400 410
pF1KB4 KGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::
XP_016 KGMKDDKEEEEDGTGSPQLNNR
430 440
>>XP_016873239 (OMIM: 107940) PREDICTED: beta-arrestin-1 (473 aa)
initn: 2492 init1: 2492 opt: 2492 Z-score: 2818.3 bits: 530.7 E(85289): 3e-150
Smith-Waterman score: 2678; 94.3% identity (94.5% similar) in 437 aa overlap (6-418:37-473)
10 20 30
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
.:::::::::::::::::::::::::::::
XP_016 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
310 320 330 340 350 360
340 350 360 370 380
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTN-------------
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNQRPSSHRTVARGG
370 380 390 400 410 420
390 400 410
pF1KB4 -----------DDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::::::::::::::::
XP_016 GPGPTARTASSDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
430 440 450 460 470
>>XP_016873242 (OMIM: 107940) PREDICTED: beta-arrestin-1 (437 aa)
initn: 2483 init1: 2483 opt: 2483 Z-score: 2808.7 bits: 528.8 E(85289): 1.1e-149
Smith-Waterman score: 2669; 94.5% identity (94.5% similar) in 435 aa overlap (8-418:3-437)
10 20 30 40 50 60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
10 20 30 40 50
70 80 90 100 110 120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
300 310 320 330 340 350
370 380 390
pF1KB4 PHREVPENETPVDTNLIELDTN------------------------DDDIVFEDFARQRL
:::::::::::::::::::::: ::::::::::::::
XP_016 PHREVPENETPVDTNLIELDTNQRPSSHRTVARGGGPGPTARTASSDDDIVFEDFARQRL
360 370 380 390 400 410
400 410
pF1KB4 KGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::
XP_016 KGMKDDKEEEEDGTGSPQLNNR
420 430
>>XP_016873243 (OMIM: 107940) PREDICTED: beta-arrestin-1 (434 aa)
initn: 2472 init1: 2204 opt: 2460 Z-score: 2782.7 bits: 523.9 E(85289): 2.9e-148
Smith-Waterman score: 2646; 92.8% identity (92.8% similar) in 442 aa overlap (1-418:1-434)
10 20 30 40 50 60
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTCA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEIP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPGP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYAD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTNL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 ASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEEP
::::::::::::::::::::::::::::::::: :::::::::::::::::::
XP_016 ASSTLLREGANREILGIIVSYKVKVKLVVSRGG--------DVAVELPFTLMHPKPKEEP
310 320 330 340 350
370 380 390
pF1KB4 PHREVPENETPVDTNLIELDTN------------------------DDDIVFEDFARQRL
:::::::::::::::::::::: ::::::::::::::
XP_016 PHREVPENETPVDTNLIELDTNQRPSSHRTVARGGGPGPTARTASSDDDIVFEDFARQRL
360 370 380 390 400 410
400 410
pF1KB4 KGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::
XP_016 KGMKDDKEEEEDGTGSPQLNNR
420 430
>>XP_016873240 (OMIM: 107940) PREDICTED: beta-arrestin-1 (465 aa)
initn: 2432 init1: 2164 opt: 2420 Z-score: 2737.0 bits: 515.6 E(85289): 1e-145
Smith-Waterman score: 2606; 92.4% identity (92.7% similar) in 437 aa overlap (6-418:37-465)
10 20 30
pF1KB4 MGDKGTRVFKKASPNGKLTVYLGKRDFVDHIDLVD
.:::::::::::::::::::::::::::::
XP_016 RERLRLHARRIQTLAFHPPQHPGAGCVALLSRVFKKASPNGKLTVYLGKRDFVDHIDLVD
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB4 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVDGVVLVDPEYLKERRVYVTLTCAFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKK
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB4 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB4 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPIS
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB4 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNVHVTNNTNKTVKKIKISVRQYADICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLT
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB4 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGGLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PFLANNREKRGLALDGKLKHEDTNLASSTLLREGANREILGIIVSYKVKVKLVVSRGG--
310 320 330 340 350 360
340 350 360 370 380
pF1KB4 GDLASSDVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTN-------------
:::::::::::::::::::::::::::::::::::::::::
XP_016 ------DVAVELPFTLMHPKPKEEPPHREVPENETPVDTNLIELDTNQRPSSHRTVARGG
370 380 390 400 410
390 400 410
pF1KB4 -----------DDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
::::::::::::::::::::::::::::::::::::
XP_016 GPGPTARTASSDDDIVFEDFARQRLKGMKDDKEEEEDGTGSPQLNNR
420 430 440 450 460
>>NP_004304 (OMIM: 107941) beta-arrestin-2 isoform 1 [Ho (409 aa)
initn: 2079 init1: 1870 opt: 2150 Z-score: 2432.5 bits: 459.1 E(85289): 9.4e-129
Smith-Waterman score: 2150; 76.4% identity (91.6% similar) in 415 aa overlap (1-407:1-407)
10 20 30 40 50
pF1KB4 MGDK-GTRVFKKASPNGKLTVYLGKRDFVDHIDLVDPVDGVVLVDPEYLKERRVYVTLTC
::.: :::::::.::: ::::::::::::::.: ::::::::::::.:::.:.:.:::::
NP_004 MGEKPGTRVFKKSSPNCKLTVYLGKRDFVDHLDKVDPVDGVVLVDPDYLKDRKVFVTLTC
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB4 AFRYGREDLDVLGLTFRKDLFVANVQSFPPAPEDKKPLTRLQERLIKKLGEHAYPFTFEI
::::::::::::::.::::::.:. :.:::.:. .: ::::.::..:::.::.:: : :
NP_004 AFRYGREDLDVLGLSFRKDLFIATYQAFPPVPNPPRPPTRLQDRLLRKLGQHAHPFFFTI
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB4 PPNLPCSVTLQPGPEDTGKACGVDYEVKAFCAENLEEKIHKRNSVRLVIRKVQYAPERPG
: ::::::::::::::::::::::.:..::::..:::: ::::::::::::::.:::.::
NP_004 PQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVIRKVQFAPEKPG
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB4 PQPTAETTRQFLMSDKPLHLEASLDKEIYYHGEPISVNVHVTNNTNKTVKKIKISVRQYA
:::.:::::.:::::. ::::::::::.::::::..::::::::..:::::::.::::::
NP_004 PQPSAETTRHFLMSDRSLHLEASLDKELYYHGEPLNVNVHVTNNSTKTVKKIKVSVRQYA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB4 DICLFNTAQYKCPVAMEEADDTVAPSSTFCKVYTLTPFLANNREKRGLALDGKLKHEDTN
:::::.:::::::::. : :: :.::::::::::.::.:..:::::::::::::::::::
NP_004 DICLFSTAQYKCPVAQLEQDDQVSPSSTFCKVYTITPLLSDNREKRGLALDGKLKHEDTN
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB4 LASSTLLREGANREILGIIVSYKVKVKLVVSRGGLLGDLASSDVAVELPFTLMHPKPKEE
:::::...::::.:.:::.:::.::::::::::: ::.:::::.::::::...
NP_004 LASSTIVKEGANKEVLGILVSYRVKVKLVVSRGG--------DVSVELPFVLMHPKPHDH
310 320 330 340 350
360 370 380 390 400 410
pF1KB4 -P---PHREVPENETPVDTNLIELDTN---DDDIVFEDFARQRLKGMKDDKEEEEDGTGS
: :. .::...::::::::.::: ::::::::::: :::::::: ...
NP_004 IPLPRPQSAAPETDVPVDTNLIEFDTNYATDDDIVFEDFARLRLKGMKDDDYDDQLC
360 370 380 390 400
pF1KB4 PQLNNR
418 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 03:19:24 2016 done: Fri Nov 4 03:19:25 2016
Total Scan time: 8.540 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]