Result of FASTA (omim) for
pFN21AB3881
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3881, 369 aa
1>>>pF1KB3881 369 - 369 aa - 369 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6606+/-0.000355; mu= 16.0190+/- 0.022
mean_var=85.6965+/-16.484, 0's: 0 Z-trim(114.8): 168 B-trim: 73 in 1/54
Lambda= 0.138546
statistics sampled from 24715 (24885) to 24715 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.292), width: 16
Scan time: 8.330
The best scores are: opt bits E(85289)
NP_002679 (OMIM: 602724) septin-5 isoform 1 [Homo ( 369) 2482 505.9 6e-143
XP_006722014 (OMIM: 603696) PREDICTED: septin-4 is ( 379) 1869 383.4 4.7e-106
NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo ( 459) 1869 383.4 5.5e-106
NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Ho ( 470) 1869 383.4 5.6e-106
NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo ( 478) 1869 383.4 5.7e-106
XP_006722012 (OMIM: 603696) PREDICTED: septin-4 is ( 483) 1869 383.4 5.7e-106
NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Ho ( 493) 1869 383.4 5.8e-106
XP_006722013 (OMIM: 603696) PREDICTED: septin-4 is ( 384) 1858 381.2 2.2e-105
XP_006722015 (OMIM: 603696) PREDICTED: septin-4 is ( 360) 1855 380.5 3.2e-105
NP_001009939 (OMIM: 602724) septin-5 isoform 2 [Ho ( 346) 1699 349.3 7.5e-96
XP_006722018 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
XP_011523213 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
XP_006722017 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
XP_011523214 (OMIM: 603696) PREDICTED: septin-4 is ( 331) 1679 345.3 1.1e-94
NP_001243751 (OMIM: 603696) septin-4 isoform 6 [Ho ( 331) 1679 345.3 1.1e-94
NP_443070 (OMIM: 612897) septin-1 [Homo sapiens] ( 414) 1569 323.4 5.7e-88
XP_016878480 (OMIM: 612897) PREDICTED: septin-1 is ( 494) 1485 306.7 7.4e-83
NP_001307958 (OMIM: 601506) septin-2 isoform d [Ho ( 391) 1361 281.8 1.8e-75
NP_001269901 (OMIM: 601506) septin-2 isoform b [Ho ( 396) 1361 281.8 1.8e-75
XP_016859680 (OMIM: 601506) PREDICTED: septin-2 is ( 428) 1361 281.9 1.9e-75
XP_016859681 (OMIM: 601506) PREDICTED: septin-2 is ( 428) 1361 281.9 1.9e-75
NP_001307960 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001008491 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
XP_016859694 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 1359 281.4 2.2e-75
NP_001307959 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001307962 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
XP_016859695 (OMIM: 601506) PREDICTED: septin-2 is ( 361) 1359 281.4 2.2e-75
NP_001307963 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001008492 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_006146 (OMIM: 601506) septin-2 isoform a [Homo ( 361) 1359 281.4 2.2e-75
NP_004395 (OMIM: 601506) septin-2 isoform a [Homo ( 361) 1359 281.4 2.2e-75
NP_001307964 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
NP_001307961 (OMIM: 601506) septin-2 isoform a [Ho ( 361) 1359 281.4 2.2e-75
XP_016859679 (OMIM: 601506) PREDICTED: septin-2 is ( 436) 1346 278.9 1.6e-74
XP_016859678 (OMIM: 601506) PREDICTED: septin-2 is ( 441) 1346 278.9 1.6e-74
XP_016859683 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859692 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859686 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859691 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859689 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859682 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859690 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859685 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859688 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859693 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859687 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016859684 (OMIM: 601506) PREDICTED: septin-2 is ( 374) 1344 278.4 1.8e-74
XP_016868346 (OMIM: 603151) PREDICTED: septin-7 is ( 434) 1277 265.1 2.2e-70
XP_016868345 (OMIM: 603151) PREDICTED: septin-7 is ( 435) 1277 265.1 2.2e-70
NP_001011553 (OMIM: 603151) septin-7 isoform 2 [Ho ( 436) 1277 265.1 2.2e-70
>>NP_002679 (OMIM: 602724) septin-5 isoform 1 [Homo sapi (369 aa)
initn: 2482 init1: 2482 opt: 2482 Z-score: 2687.3 bits: 505.9 E(85289): 6e-143
Smith-Waterman score: 2482; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEELRRMQEMLQ
310 320 330 340 350 360
pF1KB3 RMKQQMQDQ
:::::::::
NP_002 RMKQQMQDQ
>>XP_006722014 (OMIM: 603696) PREDICTED: septin-4 isofor (379 aa)
initn: 1900 init1: 1724 opt: 1869 Z-score: 2025.0 bits: 383.4 E(85289): 4.7e-106
Smith-Waterman score: 1909; 76.4% identity (90.8% similar) in 368 aa overlap (12-368:11-377)
10 20 30 40 50
pF1KB3 MSTGLRYKSKLATPEDKQDI--DKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS
..:::. . ::.:::::::::::::::::::::::::::::::::::
XP_006 MDRSLGWQGNSVPEDRTEAGDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKS
10 20 30 40 50
60 70 80 90 100 110
pF1KB3 TLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNN
:::.::::::::.:::::.::::: ::::: ::.::::::::.:.:::::::::::::::
XP_006 TLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNN
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB3 TECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKAL
::::::...:.::::::::::::::::::::::::::::::::::::::::.:: :::::
XP_006 TECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKAL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB3 HEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDREL
:..:::::..:::: :.: :. . :..:::::..:::..::::.:::::::::: ::. :
XP_006 HQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQAL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB3 KESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDV
::: :::::::::::::.:.:::::::::::::::: .::::::::.::.::::.:::::
XP_006 KESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDV
240 250 260 270 280 290
300 310 320 330 340
pF1KB3 TCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKD
: ..:::::::.:::.:: .:::..: . ::: .: : : ::::::: ::
XP_006 TRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKD
300 310 320 330 340 350
350 360
pF1KB3 EELRRMQEMLQRMKQQMQDQ
::::::::::.....::..
XP_006 EELRRMQEMLHKIQKQMKENY
360 370
>>NP_536341 (OMIM: 603696) septin-4 isoform 3 [Homo sapi (459 aa)
initn: 1900 init1: 1724 opt: 1869 Z-score: 2023.8 bits: 383.4 E(85289): 5.5e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:95-457)
10 20 30 40
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
: :... ::.::::::::::::::::::::
NP_536 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_536 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
:::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_536 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_536 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
250 260 270 280 290 300
230 240 250 260 270 280
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_536 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
310 320 330 340 350 360
290 300 310 320 330
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
:.::.::::.:::::: ..:::::::.:::.:: .:::..: . ::: .:
NP_536 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
370 380 390 400 410 420
340 350 360
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
: : ::::::: ::::::::::::.....::..
NP_536 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
430 440 450
>>NP_001185642 (OMIM: 603696) septin-4 isoform 4 [Homo s (470 aa)
initn: 1900 init1: 1724 opt: 1869 Z-score: 2023.6 bits: 383.4 E(85289): 5.6e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:106-468)
10 20 30 40
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
: :... ::.::::::::::::::::::::
NP_001 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
80 90 100 110 120 130
50 60 70 80 90 100
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_001 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
140 150 160 170 180 190
110 120 130 140 150 160
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
:::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_001 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
200 210 220 230 240 250
170 180 190 200 210 220
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_001 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
260 270 280 290 300 310
230 240 250 260 270 280
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_001 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
320 330 340 350 360 370
290 300 310 320 330
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
:.::.::::.:::::: ..:::::::.:::.:: .:::..: . ::: .:
NP_001 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
380 390 400 410 420 430
340 350 360
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
: : ::::::: ::::::::::::.....::..
NP_001 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
440 450 460 470
>>NP_004565 (OMIM: 603696) septin-4 isoform 1 [Homo sapi (478 aa)
initn: 1900 init1: 1724 opt: 1869 Z-score: 2023.5 bits: 383.4 E(85289): 5.7e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:114-476)
10 20 30 40
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
: :... ::.::::::::::::::::::::
NP_004 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_004 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
150 160 170 180 190 200
110 120 130 140 150 160
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
:::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_004 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
210 220 230 240 250 260
170 180 190 200 210 220
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_004 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
270 280 290 300 310 320
230 240 250 260 270 280
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_004 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
330 340 350 360 370 380
290 300 310 320 330
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
:.::.::::.:::::: ..:::::::.:::.:: .:::..: . ::: .:
NP_004 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
390 400 410 420 430 440
340 350 360
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
: : ::::::: ::::::::::::.....::..
NP_004 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
450 460 470
>>XP_006722012 (OMIM: 603696) PREDICTED: septin-4 isofor (483 aa)
initn: 1900 init1: 1724 opt: 1869 Z-score: 2023.5 bits: 383.4 E(85289): 5.7e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:119-481)
10 20 30 40
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
: :... ::.::::::::::::::::::::
XP_006 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
90 100 110 120 130 140
50 60 70 80 90 100
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
XP_006 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
150 160 170 180 190 200
110 120 130 140 150 160
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
:::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
XP_006 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
210 220 230 240 250 260
170 180 190 200 210 220
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
XP_006 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
270 280 290 300 310 320
230 240 250 260 270 280
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
XP_006 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
330 340 350 360 370 380
290 300 310 320 330
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
:.::.::::.:::::: ..:::::::.:::.:: .:::..: . ::: .:
XP_006 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
390 400 410 420 430 440
340 350 360
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
: : ::::::: ::::::::::::.....::..
XP_006 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
450 460 470 480
>>NP_001243711 (OMIM: 603696) septin-4 isoform 5 [Homo s (493 aa)
initn: 1900 init1: 1724 opt: 1869 Z-score: 2023.3 bits: 383.4 E(85289): 5.8e-106
Smith-Waterman score: 1909; 76.9% identity (91.2% similar) in 364 aa overlap (14-368:129-491)
10 20 30 40
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGF
: :... ::.::::::::::::::::::::
NP_001 PQSSDNQQYFCAPAPLSPSARPRSPWGKLDPYDSSEDDKEYVGFATLPNQVHRKSVKKGF
100 110 120 130 140 150
50 60 70 80 90 100
pF1KB3 DFTLMVAGESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLK
::::::::::::::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.
NP_001 DFTLMVAGESGLGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLR
160 170 180 190 200 210
110 120 130 140 150 160
pF1KB3 LTIVDTPGFGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
:::::::::::::::::::::...:.::::::::::::::::::::::::::::::::::
NP_001 LTIVDTPGFGDAVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPF
220 230 240 250 260 270
170 180 190 200 210 220
pF1KB3 GHGLRPVDVGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPEC
::::::.:: ::::::..:::::..:::: :.: :. . :..:::::..:::..::::.:
NP_001 GHGLRPLDVEFMKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDC
280 290 300 310 320 330
230 240 250 260 270 280
pF1KB3 DSDEDEDFKQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKL
::::::::: ::. :::: :::::::::::::.:.:::::::::::::::: .:::::::
NP_001 DSDEDEDFKLQDQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKL
340 350 360 370 380 390
290 300 310 320 330
pF1KB3 RNMLIRTHMHDLKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPL
:.::.::::.:::::: ..:::::::.:::.:: .:::..: . ::: .:
NP_001 RTMLVRTHMQDLKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-
400 410 420 430 440 450
340 350 360
pF1KB3 PTPDAETEKLIRMKDEELRRMQEMLQRMKQQMQDQ
: : ::::::: ::::::::::::.....::..
NP_001 PGTDPETEKLIREKDEELRRMQEMLHKIQKQMKENY
460 470 480 490
>>XP_006722013 (OMIM: 603696) PREDICTED: septin-4 isofor (384 aa)
initn: 1900 init1: 1724 opt: 1858 Z-score: 2013.0 bits: 381.2 E(85289): 2.2e-105
Smith-Waterman score: 1898; 74.8% identity (88.9% similar) in 377 aa overlap (2-368:7-382)
10 20 30 40 50
pF1KB3 MSTGLRYKSKLATPEDKQDID-KQYVGFATLPNQVHRKSVKKGFDFTLMVAGESG
: : : . . : . .: :.:::::::::::::::::::::::::::::::
XP_006 MGPVPTSFGKRRGGPQTLPASPGGMDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 LGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGD
:::::::.::::::::.:::::.::::: ::::: ::.::::::::.:.:::::::::::
XP_006 LGKSTLVNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGD
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 AVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGF
::::::::::...:.::::::::::::::::::::::::::::::::::::::::.:: :
XP_006 AVNNTECWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEF
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 MKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQ
:::::..:::::..:::: :.: :. . :..:::::..:::..::::.:::::::::: :
XP_006 MKALHQRVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQ
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 DRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHD
:. :::: :::::::::::::.:.:::::::::::::::: .::::::::.::.::::.:
XP_006 DQALKESIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQD
250 260 270 280 290 300
300 310 320 330 340
pF1KB3 LKDVTCDVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPLPTPDAETEKLI
::::: ..:::::::.:::.:: .:::..: . ::: .: : : ::::::
XP_006 LKDVTRETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLI
310 320 330 340 350
350 360
pF1KB3 RMKDEELRRMQEMLQRMKQQMQDQ
: ::::::::::::.....::..
XP_006 REKDEELRRMQEMLHKIQKQMKENY
360 370 380
>>XP_006722015 (OMIM: 603696) PREDICTED: septin-4 isofor (360 aa)
initn: 1900 init1: 1724 opt: 1855 Z-score: 2010.1 bits: 380.5 E(85289): 3.2e-105
Smith-Waterman score: 1895; 77.9% identity (91.6% similar) in 357 aa overlap (21-368:3-358)
10 20 30 40 50 60
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
::.:::::::::::::::::::::::::::::::::::::
XP_006 MDDKEYVGFATLPNQVHRKSVKKGFDFTLMVAGESGLGKSTL
10 20 30 40
70 80 90 100 110 120
pF1KB3 VHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPGFGDAVNNTE
:.::::::::.:::::.::::: ::::: ::.::::::::.:.:::::::::::::::::
XP_006 VNSLFLTDLYRDRKLLGAEERIMQTVEITKHAVDIEEKGVRLRLTIVDTPGFGDAVNNTE
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB3 CWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVDVGFMKALHE
::::...:.::::::::::::::::::::::::::::::::::::::::.:: ::::::.
XP_006 CWKPVAEYIDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPLDVEFMKALHQ
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB3 KVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDFKQQDRELKE
.:::::..:::: :.: :. . :..:::::..:::..::::.:::::::::: ::. :::
XP_006 RVNIVPILAKADTLTPPEVDHKKRKIREEIEHFGIKIYQFPDCDSDEDEDFKLQDQALKE
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB3 SAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTHMHDLKDVTC
: :::::::::::::.:.:::::::::::::::: .::::::::.::.::::.::::::
XP_006 SIPFAVIGSNTVVEARGRRVRGRLYPWGIVEVENPGHCDFVKLRTMLVRTHMQDLKDVTR
230 240 250 260 270 280
310 320 330 340 350
pF1KB3 DVHYENYRAHCIQQMT---------SKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEE
..:::::::.:::.:: .:::..: . ::: .: : : ::::::: ::::
XP_006 ETHYENYRAQCIQSMTRLVVKERNRNKLTRESGTDFPIPAVP-PGTDPETEKLIREKDEE
290 300 310 320 330 340
360
pF1KB3 LRRMQEMLQRMKQQMQDQ
::::::::.....::..
XP_006 LRRMQEMLHKIQKQMKENY
350 360
>>NP_001009939 (OMIM: 602724) septin-5 isoform 2 [Homo s (346 aa)
initn: 1699 init1: 1699 opt: 1699 Z-score: 1841.9 bits: 349.3 E(85289): 7.5e-96
Smith-Waterman score: 1699; 99.6% identity (100.0% similar) in 254 aa overlap (18-271:27-280)
10 20 30 40 50
pF1KB3 MSTGLRYKSKLATPEDKQDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAG
.:::::::::::::::::::::::::::::::::
NP_001 MDSLAAPQDRLVEQLLSPRTQAQRRLKDIDKQYVGFATLPNQVHRKSVKKGFDFTLMVAG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 ESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESGLGKSTLVHSLFLTDLYKDRKLLSAEERISQTVEILKHTVDIEEKGVKLKLTIVDTPG
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB3 FGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FGDAVNNTECWKPITDYVDQQFEQYFRDESGLNRKNIQDNRVHCCLYFISPFGHGLRPVD
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB3 VGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VGFMKALHEKVNIVPLIAKADCLVPSEIRKLKERIREEIDKFGIHVYQFPECDSDEDEDF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB3 KQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEVENQAHCDFVKLRNMLIRTH
::::::::::::::::::::::::::::::::::::::::
NP_001 KQQDRELKESAPFAVIGSNTVVEAKGQRVRGRLYPWGIVEGALRLREAAQHAHPHAYARP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB3 MHDLKDVTCDVHYENYRAHCIQQMTSKLTQDSRMESPIPILPLPTPDAETEKLIRMKDEE
NP_001 QGRDVRRALRELPRALHPADDQQTDPGQPHGEPHPDPAAAHPGRRD
310 320 330 340
369 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:42:45 2016 done: Fri Nov 4 02:42:47 2016
Total Scan time: 8.330 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]