Result of FASTA (omim) for
pFN21AB3474
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3474, 197 aa
1>>>pF1KB3474 197 - 197 aa - 197 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.5221+/-0.000333; mu= 8.4057+/- 0.021
mean_var=104.9992+/-20.439, 0's: 0 Z-trim(118.0): 10 B-trim: 48 in 1/52
Lambda= 0.125165
statistics sampled from 30530 (30540) to 30530 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.726), E-opt: 0.2 (0.358), width: 16
Scan time: 6.360
The best scores are: opt bits E(85289)
XP_016881269 (OMIM: 159430) PREDICTED: Golli-MBP i ( 197) 1303 245.1 5.4e-65
NP_001020271 (OMIM: 159430) Golli-MBP isoform 2 [H ( 197) 1303 245.1 5.4e-65
NP_001020272 (OMIM: 159430) Golli-MBP isoform 1 [H ( 304) 1277 240.5 2e-63
XP_011524311 (OMIM: 159430) PREDICTED: Golli-MBP i ( 384) 1277 240.6 2.4e-63
XP_016881267 (OMIM: 159430) PREDICTED: Golli-MBP i ( 225) 1020 194.0 1.5e-49
NP_002376 (OMIM: 159430) myelin basic protein isof ( 186) 414 84.6 1.1e-16
NP_001020252 (OMIM: 159430) myelin basic protein i ( 197) 414 84.6 1.1e-16
NP_001020263 (OMIM: 159430) myelin basic protein i ( 160) 410 83.8 1.6e-16
NP_001020261 (OMIM: 159430) myelin basic protein i ( 171) 410 83.8 1.7e-16
>>XP_016881269 (OMIM: 159430) PREDICTED: Golli-MBP isofo (197 aa)
initn: 1303 init1: 1303 opt: 1303 Z-score: 1287.8 bits: 245.1 E(85289): 5.4e-65
Smith-Waterman score: 1303; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KB3 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
130 140 150 160 170 180
190
pF1KB3 GDRGAPKRGSGKVSSEE
:::::::::::::::::
XP_016 GDRGAPKRGSGKVSSEE
190
>>NP_001020271 (OMIM: 159430) Golli-MBP isoform 2 [Homo (197 aa)
initn: 1303 init1: 1303 opt: 1303 Z-score: 1287.8 bits: 245.1 E(85289): 5.4e-65
Smith-Waterman score: 1303; 100.0% identity (100.0% similar) in 197 aa overlap (1-197:1-197)
10 20 30 40 50 60
pF1KB3 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
130 140 150 160 170 180
190
pF1KB3 GDRGAPKRGSGKVSSEE
:::::::::::::::::
NP_001 GDRGAPKRGSGKVSSEE
190
>>NP_001020272 (OMIM: 159430) Golli-MBP isoform 1 [Homo (304 aa)
initn: 1319 init1: 1277 opt: 1277 Z-score: 1259.6 bits: 240.5 E(85289): 2e-63
Smith-Waterman score: 1277; 99.5% identity (99.5% similar) in 194 aa overlap (1-194:1-194)
10 20 30 40 50 60
pF1KB3 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
130 140 150 160 170 180
190
pF1KB3 GDRGAPKRGSGKVSSEE
:::::::::::: :
NP_001 GDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKG
190 200 210 220 230 240
>>XP_011524311 (OMIM: 159430) PREDICTED: Golli-MBP isofo (384 aa)
initn: 1302 init1: 1277 opt: 1277 Z-score: 1258.2 bits: 240.6 E(85289): 2.4e-63
Smith-Waterman score: 1277; 99.5% identity (99.5% similar) in 194 aa overlap (1-194:1-194)
10 20 30 40 50 60
pF1KB3 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGNHAGKRELNAEKASTNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DTAVTDSKRTADPKNAWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFG
130 140 150 160 170 180
190
pF1KB3 GDRGAPKRGSGKVSSEE
:::::::::::: :
XP_011 GDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHFFKNIVTPRTPPPSQGKG
190 200 210 220 230 240
>>XP_016881267 (OMIM: 159430) PREDICTED: Golli-MBP isofo (225 aa)
initn: 1020 init1: 1020 opt: 1020 Z-score: 1010.8 bits: 194.0 E(85289): 1.5e-49
Smith-Waterman score: 1020; 99.3% identity (100.0% similar) in 152 aa overlap (46-197:74-225)
20 30 40 50 60 70
pF1KB3 STNSETNRGESEKKRNLGELSRTTSEDNEVFGEADANQNNGTSSQDTAVTDSKRTADPKN
.:::::::::::::::::::::::::::::
XP_016 AICLEWPLKSQSIQDGKPRRQTRIKCREGQYGEADANQNNGTSSQDTAVTDSKRTADPKN
50 60 70 80 90 100
80 90 100 110 120 130
pF1KB3 AWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AWQDAHPADPGSRPHLIRLFSRDAPGREDNTFKDRPSESDELQTIQEDSAATSESLDVMA
110 120 130 140 150 160
140 150 160 170 180 190
pF1KB3 SQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQKRPSQRHGSKYLATASTMDHARHGFLPRHRDTGILDSIGRFFGGDRGAPKRGSGKVSS
170 180 190 200 210 220
pF1KB3 EE
::
XP_016 EE
>>NP_002376 (OMIM: 159430) myelin basic protein isoform (186 aa)
initn: 414 init1: 414 opt: 414 Z-score: 420.6 bits: 84.6 E(85289): 1.1e-16
Smith-Waterman score: 414; 100.0% identity (100.0% similar) in 60 aa overlap (134-193:1-60)
110 120 130 140 150 160
pF1KB3 DNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFL
::::::::::::::::::::::::::::::
NP_002 MASQKRPSQRHGSKYLATASTMDHARHGFL
10 20 30
170 180 190
pF1KB3 PRHRDTGILDSIGRFFGGDRGAPKRGSGKVSSEE
::::::::::::::::::::::::::::::
NP_002 PRHRDTGILDSIGRFFGGDRGAPKRGSGKVPWLKPGRSPLPSHARSQPGLCNMYKDSHHP
40 50 60 70 80 90
>>NP_001020252 (OMIM: 159430) myelin basic protein isofo (197 aa)
initn: 414 init1: 414 opt: 414 Z-score: 420.2 bits: 84.6 E(85289): 1.1e-16
Smith-Waterman score: 414; 100.0% identity (100.0% similar) in 60 aa overlap (134-193:1-60)
110 120 130 140 150 160
pF1KB3 DNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFL
::::::::::::::::::::::::::::::
NP_001 MASQKRPSQRHGSKYLATASTMDHARHGFL
10 20 30
170 180 190
pF1KB3 PRHRDTGILDSIGRFFGGDRGAPKRGSGKVSSEE
::::::::::::::::::::::::::::::
NP_001 PRHRDTGILDSIGRFFGGDRGAPKRGSGKVPWLKPGRSPLPSHARSQPGLCNMYKDSHHP
40 50 60 70 80 90
>>NP_001020263 (OMIM: 159430) myelin basic protein isofo (160 aa)
initn: 426 init1: 410 opt: 410 Z-score: 417.6 bits: 83.8 E(85289): 1.6e-16
Smith-Waterman score: 410; 98.4% identity (98.4% similar) in 61 aa overlap (134-194:1-61)
110 120 130 140 150 160
pF1KB3 DNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFL
::::::::::::::::::::::::::::::
NP_001 MASQKRPSQRHGSKYLATASTMDHARHGFL
10 20 30
170 180 190
pF1KB3 PRHRDTGILDSIGRFFGGDRGAPKRGSGKVSSEE
::::::::::::::::::::::::::::: :
NP_001 PRHRDTGILDSIGRFFGGDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHF
40 50 60 70 80 90
NP_001 FKNIVTPRTPPPSQGKGAEGQRPGFGYGGRASDYKSAHKGFKGVDAQGTLSKIFKLGGRD
100 110 120 130 140 150
>>NP_001020261 (OMIM: 159430) myelin basic protein isofo (171 aa)
initn: 426 init1: 410 opt: 410 Z-score: 417.2 bits: 83.8 E(85289): 1.7e-16
Smith-Waterman score: 410; 98.4% identity (98.4% similar) in 61 aa overlap (134-194:1-61)
110 120 130 140 150 160
pF1KB3 DNTFKDRPSESDELQTIQEDSAATSESLDVMASQKRPSQRHGSKYLATASTMDHARHGFL
::::::::::::::::::::::::::::::
NP_001 MASQKRPSQRHGSKYLATASTMDHARHGFL
10 20 30
170 180 190
pF1KB3 PRHRDTGILDSIGRFFGGDRGAPKRGSGKVSSEE
::::::::::::::::::::::::::::: :
NP_001 PRHRDTGILDSIGRFFGGDRGAPKRGSGKDSHHPARTAHYGSLPQKSHGRTQDENPVVHF
40 50 60 70 80 90
NP_001 FKNIVTPRTPPPSQGKGRGLSLSRFSWGAEGQRPGFGYGGRASDYKSAHKGFKGVDAQGT
100 110 120 130 140 150
197 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:30:24 2016 done: Fri Nov 4 02:30:25 2016
Total Scan time: 6.360 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]