Result of FASTA (omim) for
pFN21AB3422
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3422, 131 aa
1>>>pF1KB3422 131 - 131 aa - 131 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.8461+/-0.000332; mu= 8.9245+/- 0.021
mean_var=81.0122+/-15.644, 0's: 0 Z-trim(116.9): 26 B-trim: 190 in 1/49
Lambda= 0.142495
statistics sampled from 28471 (28497) to 28471 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.702), E-opt: 0.2 (0.334), width: 16
Scan time: 5.090
The best scores are: opt bits E(85289)
NP_059140 (OMIM: 607268) chromatin accessibility c ( 131) 819 177.2 6.9e-45
NP_001136062 (OMIM: 605344) nuclear transcription ( 301) 184 46.8 2.7e-05
NP_063949 (OMIM: 607269) DNA polymerase epsilon su ( 117) 178 45.4 2.9e-05
NP_001136059 (OMIM: 605344) nuclear transcription ( 334) 184 46.8 3e-05
XP_016856857 (OMIM: 605344) PREDICTED: nuclear tra ( 335) 184 46.8 3e-05
XP_006710725 (OMIM: 605344) PREDICTED: nuclear tra ( 335) 184 46.8 3e-05
NP_055038 (OMIM: 605344) nuclear transcription fac ( 335) 184 46.8 3e-05
XP_016856858 (OMIM: 605344) PREDICTED: nuclear tra ( 335) 184 46.8 3e-05
NP_001136060 (OMIM: 605344) nuclear transcription ( 354) 184 46.9 3.1e-05
XP_016856856 (OMIM: 605344) PREDICTED: nuclear tra ( 354) 184 46.9 3.1e-05
XP_006710723 (OMIM: 605344) PREDICTED: nuclear tra ( 354) 184 46.9 3.1e-05
XP_016856855 (OMIM: 605344) PREDICTED: nuclear tra ( 355) 184 46.9 3.1e-05
XP_011539819 (OMIM: 605344) PREDICTED: nuclear tra ( 427) 184 46.9 3.6e-05
XP_006710724 (OMIM: 605344) PREDICTED: nuclear tra ( 439) 184 46.9 3.7e-05
XP_006710721 (OMIM: 605344) PREDICTED: nuclear tra ( 439) 184 46.9 3.7e-05
NP_001295044 (OMIM: 605344) nuclear transcription ( 439) 184 46.9 3.7e-05
XP_005270951 (OMIM: 605344) PREDICTED: nuclear tra ( 458) 184 46.9 3.9e-05
NP_001295043 (OMIM: 605344) nuclear transcription ( 458) 184 46.9 3.9e-05
XP_016856854 (OMIM: 605344) PREDICTED: nuclear tra ( 458) 184 46.9 3.9e-05
XP_011539818 (OMIM: 605344) PREDICTED: nuclear tra ( 458) 184 46.9 3.9e-05
XP_005270952 (OMIM: 605344) PREDICTED: nuclear tra ( 458) 184 46.9 3.9e-05
XP_016856853 (OMIM: 605344) PREDICTED: nuclear tra ( 459) 184 46.9 3.9e-05
>>NP_059140 (OMIM: 607268) chromatin accessibility compl (131 aa)
initn: 819 init1: 819 opt: 819 Z-score: 926.9 bits: 177.2 E(85289): 6.9e-45
Smith-Waterman score: 819; 100.0% identity (100.0% similar) in 131 aa overlap (1-131:1-131)
10 20 30 40 50 60
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVLTAKATELFVQCLATYS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 YRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYLKMLKEEKREEDEENDN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_059 YRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYLKMLKEEKREEDEENDN
70 80 90 100 110 120
130
pF1KB3 DNESDHDEADS
:::::::::::
NP_059 DNESDHDEADS
130
>>NP_001136062 (OMIM: 605344) nuclear transcription fact (301 aa)
initn: 195 init1: 177 opt: 184 Z-score: 216.0 bits: 46.8 E(85289): 2.7e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
NP_001 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
NP_001 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
NP_001 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>NP_063949 (OMIM: 607269) DNA polymerase epsilon subuni (117 aa)
initn: 178 init1: 178 opt: 178 Z-score: 215.5 bits: 45.4 E(85289): 2.9e-05
Smith-Waterman score: 178; 36.2% identity (68.8% similar) in 80 aa overlap (15-94:37-116)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:: :::.:.....:..:.:. .:::. .
NP_063 AGSGTPREEEGPAGEAAASQPQAPTSVPGARLSRLPLARVKALVKADPDVTLAGQEAIFI
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:.:.::::. .: .: .. ..:.: :: :. . . : :: :
NP_063 LARAAELFVETIAKDAYCCAQQGKRKTLQRRDLDNAIEAVDEFAFLEGTLD
70 80 90 100 110
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
>>NP_001136059 (OMIM: 605344) nuclear transcription fact (334 aa)
initn: 195 init1: 177 opt: 184 Z-score: 215.3 bits: 46.8 E(85289): 3e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
NP_001 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
NP_001 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
NP_001 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>XP_016856857 (OMIM: 605344) PREDICTED: nuclear transcr (335 aa)
initn: 195 init1: 177 opt: 184 Z-score: 215.3 bits: 46.8 E(85289): 3e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
XP_016 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
XP_016 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
XP_016 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>XP_006710725 (OMIM: 605344) PREDICTED: nuclear transcr (335 aa)
initn: 195 init1: 177 opt: 184 Z-score: 215.3 bits: 46.8 E(85289): 3e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
XP_006 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
XP_006 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
XP_006 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>NP_055038 (OMIM: 605344) nuclear transcription factor (335 aa)
initn: 195 init1: 177 opt: 184 Z-score: 215.3 bits: 46.8 E(85289): 3e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
NP_055 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
NP_055 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
NP_055 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>XP_016856858 (OMIM: 605344) PREDICTED: nuclear transcr (335 aa)
initn: 195 init1: 177 opt: 184 Z-score: 215.3 bits: 46.8 E(85289): 3e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
XP_016 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
XP_016 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
XP_016 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>NP_001136060 (OMIM: 605344) nuclear transcription fact (354 aa)
initn: 195 init1: 177 opt: 184 Z-score: 214.9 bits: 46.9 E(85289): 3.1e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
NP_001 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
NP_001 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
NP_001 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
>>XP_016856856 (OMIM: 605344) PREDICTED: nuclear transcr (354 aa)
initn: 195 init1: 177 opt: 184 Z-score: 214.9 bits: 46.9 E(85289): 3.1e-05
Smith-Waterman score: 184; 34.7% identity (63.4% similar) in 101 aa overlap (15-115:39-131)
10 20 30 40
pF1KB3 MADVVVGKDKGGEQRLISLPLSRIRVIMKSSPEVSSINQEALVL
:. :::.::. ::: . .:. :. :: ::
XP_016 GTSSSDAQQSLQSFWPRVMEEIRNLTVKDFRVQELPLARIKKIMKLDEDVKMISAEAPVL
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 TAKATELFVQCLATYSYRHGSGKEKKVLTYSDLANTAQQSETFQFLADILPKKILASKYL
:::...:. :. .. : .....: .:.: . . . :.:: ::.:.
XP_016 FAKAAQIFITELTLRAWIHTEDNKRRTLQRNDIAMAITKFDQFDFLIDIVPRD-------
70 80 90 100 110 120
110 120 130
pF1KB3 KMLKEEKREEDEENDNDNESDHDEADS
:: ::.:.
XP_016 -ELKPPKRQEEVRQSVTPAEPVQYYFTLAQQPTAVQVQGQQQGQQTTSSTTTIQPGQIII
130 140 150 160 170 180
131 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:22:09 2016 done: Fri Nov 4 02:22:10 2016
Total Scan time: 5.090 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]