Result of FASTA (omim) for
pFN21AB1226
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB1226, 1222 aa
1>>>pF1KB1226 1222 - 1222 aa - 1222 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.9689+/-0.00051; mu= 19.1105+/- 0.032
mean_var=76.8313+/-15.227, 0's: 0 Z-trim(108.7): 18 B-trim: 498 in 1/50
Lambda= 0.146320
statistics sampled from 16811 (16822) to 16811 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.197), width: 16
Scan time: 13.060
The best scores are: opt bits E(85289)
NP_775885 (OMIM: 609158) nodal modulator 2 isoform (1222) 8017 1703.0 0
NP_001004060 (OMIM: 609158) nodal modulator 2 isof (1267) 8017 1703.1 0
NP_001004067 (OMIM: 609159) nodal modulator 3 prec (1222) 7996 1698.6 0
XP_005255375 (OMIM: 609159) PREDICTED: nodal modul (1267) 7996 1698.6 0
NP_055102 (OMIM: 609157) nodal modulator 1 precurs (1222) 7976 1694.4 0
XP_016855194 (OMIM: 609159) PREDICTED: nodal modul ( 811) 5152 1098.2 0
XP_016878645 (OMIM: 609158) PREDICTED: nodal modul ( 651) 3960 846.5 0
>>NP_775885 (OMIM: 609158) nodal modulator 2 isoform 2 p (1222 aa)
initn: 8017 init1: 8017 opt: 8017 Z-score: 9138.7 bits: 1703.0 E(85289): 0
Smith-Waterman score: 8017; 99.9% identity (99.9% similar) in 1222 aa overlap (1-1222:1-1222)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_775 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
1150 1160 1170 1180 1190 1200
1210 1220
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
::::::::::::::::::::::
NP_775 ASDNSGPEDAKRQAKKQKTRRT
1210 1220
>>NP_001004060 (OMIM: 609158) nodal modulator 2 isoform (1267 aa)
initn: 8017 init1: 8017 opt: 8017 Z-score: 9138.4 bits: 1703.1 E(85289): 0
Smith-Waterman score: 8017; 99.9% identity (99.9% similar) in 1222 aa overlap (1-1222:1-1222)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
1150 1160 1170 1180 1190 1200
1210 1220
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
::::::::::::::::::::::
NP_001 ASDNSGPEDAKRQAKKQKTRRTLRLQEEFQLMWCLVPWRGTLGIHLFSSLPFASEILLET
1210 1220 1230 1240 1250 1260
>>NP_001004067 (OMIM: 609159) nodal modulator 3 precurso (1222 aa)
initn: 7996 init1: 7996 opt: 7996 Z-score: 9114.7 bits: 1698.6 E(85289): 0
Smith-Waterman score: 7996; 99.7% identity (99.8% similar) in 1222 aa overlap (1-1222:1-1222)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
NP_001 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGQISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
NP_001 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKANPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_001 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
1150 1160 1170 1180 1190 1200
1210 1220
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
::::::::::::::::::::::
NP_001 ASDNSGPEDAKRQAKKQKTRRT
1210 1220
>>XP_005255375 (OMIM: 609159) PREDICTED: nodal modulator (1267 aa)
initn: 7996 init1: 7996 opt: 7996 Z-score: 9114.5 bits: 1698.6 E(85289): 0
Smith-Waterman score: 7996; 99.7% identity (99.8% similar) in 1222 aa overlap (1-1222:1-1222)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_005 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGQISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
:::::::::::::::::::::::::::::::::::::.::::::::::::::::::::::
XP_005 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKANPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_005 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
1150 1160 1170 1180 1190 1200
1210 1220
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
::::::::::::::::::::::
XP_005 ASDNSGPEDAKRQAKKQKTRRTLRLQEEFQLMWCLVPWRGTLGIHLFSSLPFASEILLET
1210 1220 1230 1240 1250 1260
>>NP_055102 (OMIM: 609157) nodal modulator 1 precursor [ (1222 aa)
initn: 7976 init1: 7976 opt: 7976 Z-score: 9091.9 bits: 1694.4 E(85289): 0
Smith-Waterman score: 7976; 99.3% identity (99.8% similar) in 1222 aa overlap (1-1222:1-1222)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MLVGQGAGPLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
:::::::::::::::::::::::::::::::::::::::::::.::::::::.:::::::
NP_055 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIIATGFSVCGQISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
:::::::::.::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_055 PQTFPLTVTNRPMMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_055 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDMSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
NP_055 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB1 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 GPLHSDLEYTVTSQKEGYVLTAVEGTIGDFKAYALAGVSFEIKAEDDQPLPGVLLSLSGG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB1 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 LFRSNLLTQDNGILTFSNLSPGQYYFKPMMKEFRFEPSSQMIEVQEGQNLKITITGYRTA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB1 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 YSCYGTVSSLNGEPEQGVAMEAVGQNDCSIYGEDTVTDEEGKFRLRGLLPGCVYHVQLKA
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB1 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 EGNDHIERALPHHRVIEVGNNDIDDVNIIVFRQINQFDLSGNVITSSEYLPTLWVKLYKS
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB1 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 ENLDNPIQTVSLGQSLFFHFPPLLRDGENYVVLLDSTLPRSQYDYILPQVSFTAVGYHKH
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KB1 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVGALGQA
:::::::::::::::::::::::::::::::::::::::::::::::::::::: :::::
NP_055 ITLIFNPTRKLPEQDIAQGSYIALPLTLLVLLAGYNHDKLIPLLLQLTSRLQGVRALGQA
1150 1160 1170 1180 1190 1200
1210 1220
pF1KB1 ASDNSGPEDAKRQAKKQKTRRT
::::::::::::::::::::::
NP_055 ASDNSGPEDAKRQAKKQKTRRT
1210 1220
>>XP_016855194 (OMIM: 609159) PREDICTED: nodal modulator (811 aa)
initn: 5152 init1: 5152 opt: 5152 Z-score: 5872.9 bits: 1098.2 E(85289): 0
Smith-Waterman score: 5152; 99.5% identity (99.6% similar) in 788 aa overlap (1-788:1-788)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB1 LTAIRHHVLGTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTAIRHHVLCTITTDKMMDVTVTIKSSIDSEPALVLGPLKSVQELRREQQLAEIEARRQE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB1 REKNGNEEGEERMTKPSVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
:::::::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_016 REKNGNEEGEERMTKPPVQEMVDELQGPFSYDFSYWARSGEKITVTPSSKELLFYPPSME
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB1 AVVSGESCPGKLIEIHGKAGLFLEGQIHPELEGVEIVISEKGASSPLITVFTDDKGAYSV
::::: .:
XP_016 AVVSGGKCQLSERMSHTPLQLFPCLHLQVDL
790 800 810
>>XP_016878645 (OMIM: 609158) PREDICTED: nodal modulator (651 aa)
initn: 3998 init1: 3960 opt: 3960 Z-score: 4514.5 bits: 846.5 E(85289): 0
Smith-Waterman score: 3960; 100.0% identity (100.0% similar) in 602 aa overlap (1-602:1-602)
10 20 30 40 50 60
pF1KB1 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLVGQGAGLLGPAVVTAAVVLLLSGVGPAHGSEDIVVGCGGFVKSDVEINYSLIEIKLYT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB1 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KHGTLKYQTDCAPNNGYFMIPLYDKGDFILKIEPPLGWSFEPTTVELHVDGVSDICTKGG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB1 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DINFVFTGFSVNGKVLSKGQPLGPAGVQVSLRNTGTEAKIQSTVTQPGGKFAFFKVLPGD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB1 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YEILATHPTWALKEASTTVRVTNSNANAASPLIVAGYNVSGSVRSDGEPMKGVKFLLFSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB1 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVTKEDVLGCNVSPVPGFQPQDESLVYLCYTVSREDGSFSFYSLPSGGYTVIPFYRGERI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB1 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFDVAPSRLDFTVEHDSLKIEPVFHVMGFSVTGRVLNGPEGDGVPEAVVTLNNQIKVKTK
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB1 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ADGSFRLENITTGTYTIHAQKEHLYFETVTIKIAPNTPQLADIVATGFSVCGRISIIRFP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB1 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DTVKQMNKYKVVLSSQDKDKSLVTVETDAHGSFCFKAKPGTYKVQVMVPEAETRAGLTLK
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB1 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PQTFPLTVTDRPVMDVAFVQFLASVSGKVSCLDTCGDLLVTLQSLSRQGEKRSLQLSGKV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB1 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAMTFTFDNVLPGKYKISIMHEDWCWKNKSLEVEVLEDDVSAVEFRQTGYMLRCSLSHAI
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB1 TLEFYQDGNGRENVGIYNLSKGVNRFCLSKPGVYKVTPRSCHRFEQAFYTYDTSSPSILT
::
XP_016 TLAQPYCSGEMCPGTSELKTPRWGLFFSCFPVYFHSFVTDQLRSLIYLLMR
610 620 630 640 650
1222 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 02:04:01 2016 done: Fri Nov 4 02:04:03 2016
Total Scan time: 13.060 Total Display time: 0.350
Function used was FASTA [36.3.4 Apr, 2011]