Result of FASTA (omim) for
pFN21AB7656
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB7656, 394 aa
1>>>pF1KB7656 394 - 394 aa - 394 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5436+/-0.000408; mu= 17.9814+/- 0.026
mean_var=122.5445+/-24.383, 0's: 0 Z-trim(114.8): 47 B-trim: 0 in 0/54
Lambda= 0.115858
statistics sampled from 24849 (24896) to 24849 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.624), E-opt: 0.2 (0.292), width: 16
Scan time: 7.490
The best scores are: opt bits E(85289)
XP_011519659 (OMIM: 615023,615276) PREDICTED: cera ( 394) 2741 469.5 6.3e-132
XP_011519660 (OMIM: 615023,615276) PREDICTED: cera ( 394) 2741 469.5 6.3e-132
XP_016877491 (OMIM: 615023,615276) PREDICTED: cera ( 394) 2741 469.5 6.3e-132
XP_011519657 (OMIM: 615023,615276) PREDICTED: cera ( 394) 2741 469.5 6.3e-132
NP_001277270 (OMIM: 615023,615276) ceramide syntha ( 394) 2741 469.5 6.3e-132
XP_016877493 (OMIM: 615023,615276) PREDICTED: cera ( 383) 2673 458.1 1.6e-128
NP_849164 (OMIM: 615023,615276) ceramide synthase ( 383) 2673 458.1 1.6e-128
NP_001277271 (OMIM: 615023,615276) ceramide syntha ( 383) 2673 458.1 1.6e-128
NP_001277272 (OMIM: 615023,615276) ceramide syntha ( 383) 2673 458.1 1.6e-128
XP_016877492 (OMIM: 615023,615276) PREDICTED: cera ( 383) 2673 458.1 1.6e-128
XP_011507753 (OMIM: 606920) PREDICTED: ceramide sy ( 400) 1450 253.7 5.8e-67
NP_071358 (OMIM: 606920) ceramide synthase 2 [Homo ( 380) 1438 251.7 2.2e-66
XP_011507754 (OMIM: 606920) PREDICTED: ceramide sy ( 380) 1438 251.7 2.2e-66
NP_859530 (OMIM: 606920) ceramide synthase 2 [Homo ( 380) 1438 251.7 2.2e-66
XP_011526597 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_011526593 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_016882793 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_011526596 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_011526595 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_016882792 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_011526594 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
XP_011526592 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
NP_078828 (OMIM: 615334) ceramide synthase 4 [Homo ( 394) 1187 209.7 9.8e-54
XP_016882794 (OMIM: 615334) PREDICTED: ceramide sy ( 394) 1187 209.7 9.8e-54
NP_671723 (OMIM: 615335) ceramide synthase 5 isofo ( 392) 1056 187.8 3.8e-47
NP_982288 (OMIM: 615336) ceramide synthase 6 isofo ( 384) 1032 183.8 6.1e-46
NP_001317999 (OMIM: 615335) ceramide synthase 5 is ( 392) 1029 183.3 8.7e-46
NP_001318000 (OMIM: 615335) ceramide synthase 5 is ( 381) 1022 182.1 1.9e-45
XP_005269277 (OMIM: 615335) PREDICTED: ceramide sy ( 409) 1022 182.2 2e-45
NP_001243055 (OMIM: 615336) ceramide synthase 6 is ( 392) 1012 180.5 6.2e-45
XP_016875693 (OMIM: 615335) PREDICTED: ceramide sy ( 290) 915 164.1 3.9e-40
NP_001268660 (OMIM: 615335) ceramide synthase 5 is ( 334) 895 160.8 4.3e-39
XP_016875691 (OMIM: 615335) PREDICTED: ceramide sy ( 334) 868 156.3 9.9e-38
NP_001317998 (OMIM: 615335) ceramide synthase 5 is ( 323) 861 155.1 2.2e-37
NP_001318001 (OMIM: 615335) ceramide synthase 5 is ( 248) 700 128.1 2.3e-29
XP_016875694 (OMIM: 615335) PREDICTED: ceramide sy ( 237) 666 122.4 1.2e-27
NP_001318002 (OMIM: 615335) ceramide synthase 5 is ( 237) 666 122.4 1.2e-27
XP_016859238 (OMIM: 615336) PREDICTED: ceramide sy ( 251) 552 103.3 6.6e-22
XP_005246497 (OMIM: 615336) PREDICTED: ceramide sy ( 200) 391 76.3 7.1e-14
NP_067090 (OMIM: 606919,616230) ceramide synthase ( 350) 216 47.4 6.5e-05
NP_937850 (OMIM: 606919,616230) ceramide synthase ( 337) 208 46.0 0.00016
NP_001277194 (OMIM: 606919,616230) ceramide syntha ( 239) 189 42.6 0.0012
>>XP_011519659 (OMIM: 615023,615276) PREDICTED: ceramide (394 aa)
initn: 2741 init1: 2741 opt: 2741 Z-score: 2489.5 bits: 469.5 E(85289): 6.3e-132
Smith-Waterman score: 2741; 99.7% identity (99.7% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
310 320 330 340 350 360
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
XP_011 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
370 380 390
>>XP_011519660 (OMIM: 615023,615276) PREDICTED: ceramide (394 aa)
initn: 2741 init1: 2741 opt: 2741 Z-score: 2489.5 bits: 469.5 E(85289): 6.3e-132
Smith-Waterman score: 2741; 99.7% identity (99.7% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
310 320 330 340 350 360
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
XP_011 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
370 380 390
>>XP_016877491 (OMIM: 615023,615276) PREDICTED: ceramide (394 aa)
initn: 2741 init1: 2741 opt: 2741 Z-score: 2489.5 bits: 469.5 E(85289): 6.3e-132
Smith-Waterman score: 2741; 99.7% identity (99.7% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
310 320 330 340 350 360
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
XP_016 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
370 380 390
>>XP_011519657 (OMIM: 615023,615276) PREDICTED: ceramide (394 aa)
initn: 2741 init1: 2741 opt: 2741 Z-score: 2489.5 bits: 469.5 E(85289): 6.3e-132
Smith-Waterman score: 2741; 99.7% identity (99.7% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
310 320 330 340 350 360
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
XP_011 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
370 380 390
>>NP_001277270 (OMIM: 615023,615276) ceramide synthase 3 (394 aa)
initn: 2741 init1: 2741 opt: 2741 Z-score: 2489.5 bits: 469.5 E(85289): 6.3e-132
Smith-Waterman score: 2741; 99.7% identity (99.7% similar) in 394 aa overlap (1-394:1-394)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
310 320 330 340 350 360
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
NP_001 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
370 380 390
>>XP_016877493 (OMIM: 615023,615276) PREDICTED: ceramide (383 aa)
initn: 2673 init1: 2673 opt: 2673 Z-score: 2428.2 bits: 458.1 E(85289): 1.6e-128
Smith-Waterman score: 2673; 99.7% identity (99.7% similar) in 383 aa overlap (12-394:1-383)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
290 300 310 320 330 340
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
XP_016 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
350 360 370 380
>>NP_849164 (OMIM: 615023,615276) ceramide synthase 3 is (383 aa)
initn: 2673 init1: 2673 opt: 2673 Z-score: 2428.2 bits: 458.1 E(85289): 1.6e-128
Smith-Waterman score: 2673; 99.7% identity (99.7% similar) in 383 aa overlap (12-394:1-383)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_849 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_849 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_849 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_849 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_849 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_849 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
290 300 310 320 330 340
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
NP_849 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
350 360 370 380
>>NP_001277271 (OMIM: 615023,615276) ceramide synthase 3 (383 aa)
initn: 2673 init1: 2673 opt: 2673 Z-score: 2428.2 bits: 458.1 E(85289): 1.6e-128
Smith-Waterman score: 2673; 99.7% identity (99.7% similar) in 383 aa overlap (12-394:1-383)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
290 300 310 320 330 340
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
NP_001 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
350 360 370 380
>>NP_001277272 (OMIM: 615023,615276) ceramide synthase 3 (383 aa)
initn: 2673 init1: 2673 opt: 2673 Z-score: 2428.2 bits: 458.1 E(85289): 1.6e-128
Smith-Waterman score: 2673; 99.7% identity (99.7% similar) in 383 aa overlap (12-394:1-383)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
290 300 310 320 330 340
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
NP_001 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
350 360 370 380
>>XP_016877492 (OMIM: 615023,615276) PREDICTED: ceramide (383 aa)
initn: 2673 init1: 2673 opt: 2673 Z-score: 2428.2 bits: 458.1 E(85289): 1.6e-128
Smith-Waterman score: 2673; 99.7% identity (99.7% similar) in 383 aa overlap (12-394:1-383)
10 20 30 40 50 60
pF1KB7 MLHTTARRAARMFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFWTFKEWFWLERFWLPPTIKWSDLEDHDGLVFVKPSHLYVTIPYAFLL
10 20 30 40
70 80 90 100 110 120
pF1KB7 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIIRRVFEKFVASPLAKSFGIKETVRKVTPNTVLENFFKHSTRQPLQTDIYGLAKKCNLT
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB7 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ERQVERWFRSRRNQERPSRLKKFQEACWRFAFYLMITVAGIAFLYDKPWLYDLWEVWNGY
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB7 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PKQPLLPSQYWYYILEMSFYWSLLFRLGFDVKRKDFLAHIIHHLAAISLMSFSWCANYIR
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB7 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SGTLVMIVHDVADIWLESAKMFSYAGWTQTCNTLFFIFSTIFFISRLIVFPFWILYCTLI
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB7 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LPMYHLEPFFSYIFLNLQLMILQVLHLYWGYYILKMLNRCIFMKSIQDVRSDDEDYEEEE
290 300 310 320 330 340
370 380 390
pF1KB7 EEEEEEATKGKEMDCLKNGLGAERHLIPNGQHGH
:::::::::::::::::::: :::::::::::::
XP_016 EEEEEEATKGKEMDCLKNGLRAERHLIPNGQHGH
350 360 370 380
394 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 09:53:52 2016 done: Sat Nov 5 09:53:54 2016
Total Scan time: 7.490 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]