Result of FASTA (omim) for
pFN21AB9511
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9511, 386 aa
1>>>pF1KB9511 386 - 386 aa - 386 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0607+/-0.000291; mu= 14.0732+/- 0.018
mean_var=85.0648+/-16.662, 0's: 0 Z-trim(119.4): 23 B-trim: 30 in 1/51
Lambda= 0.139059
statistics sampled from 33320 (33343) to 33320 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.74), E-opt: 0.2 (0.391), width: 16
Scan time: 9.490
The best scores are: opt bits E(85289)
NP_057231 (OMIM: 611117) protein phosphatase methy ( 386) 2599 530.7 2.2e-150
XP_016873402 (OMIM: 611117) PREDICTED: protein pho ( 278) 1826 375.6 8e-104
NP_001258522 (OMIM: 611117) protein phosphatase me ( 400) 1826 375.6 1.1e-103
NP_001243514 (OMIM: 609699) monoglyceride lipase i ( 283) 155 40.3 0.0067
XP_011510679 (OMIM: 609699) PREDICTED: monoglyceri ( 339) 156 40.6 0.0068
NP_009214 (OMIM: 609699) monoglyceride lipase isof ( 313) 155 40.4 0.0073
XP_016861155 (OMIM: 609699) PREDICTED: monoglyceri ( 273) 153 39.9 0.0086
XP_011510680 (OMIM: 609699) PREDICTED: monoglyceri ( 329) 154 40.2 0.0088
NP_001003794 (OMIM: 609699) monoglyceride lipase i ( 303) 153 39.9 0.0094
XP_016861151 (OMIM: 609699) PREDICTED: monoglyceri ( 305) 153 39.9 0.0095
>>NP_057231 (OMIM: 611117) protein phosphatase methylest (386 aa)
initn: 2599 init1: 2599 opt: 2599 Z-score: 2820.9 bits: 530.7 E(85289): 2.2e-150
Smith-Waterman score: 2599; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386)
10 20 30 40 50 60
pF1KB9 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 KNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 KNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 DVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 ITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 ITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 WFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_057 WFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVA
310 320 330 340 350 360
370 380
pF1KB9 EAVATFLIRHRFAEPIGGFQCVFPGC
::::::::::::::::::::::::::
NP_057 EAVATFLIRHRFAEPIGGFQCVFPGC
370 380
>>XP_016873402 (OMIM: 611117) PREDICTED: protein phospha (278 aa)
initn: 1826 init1: 1826 opt: 1826 Z-score: 1984.9 bits: 375.6 E(85289): 8e-104
Smith-Waterman score: 1826; 100.0% identity (100.0% similar) in 278 aa overlap (1-278:1-278)
10 20 30 40 50 60
pF1KB9 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 KNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEG
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 ITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMETKKDHPYTWRIELAKTEKYWDG
::::::::::::::::::::::::::::::::::::::
XP_016 ITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDME
250 260 270
310 320 330 340 350 360
pF1KB9 WFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVA
>>NP_001258522 (OMIM: 611117) protein phosphatase methyl (400 aa)
initn: 1826 init1: 1826 opt: 1826 Z-score: 1982.5 bits: 375.6 E(85289): 1.1e-103
Smith-Waterman score: 2561; 96.5% identity (96.5% similar) in 400 aa overlap (1-386:1-400)
10 20 30 40 50 60
pF1KB9 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVEN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSPVPWSQYFESMEDVEVEN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 ETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ETGKDTFRVYKSGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 KNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KNPEDLSAETMAKDVGNVVEAMYGDLPPPIMLIGHSMGGAIAVHTASSNLVPSLLGLCMI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 DVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEG
190 200 210 220 230 240
250 260 270 280
pF1KB9 ITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDME--------------TKKDHPYT
:::::::::::::::::::::::::::::::::::::: ::::::::
NP_001 ITSPEGSKSIVEGIIEEEEEDEEGSESISKRKKEDDMEGLPSETQNLLLFLQTKKDHPYT
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB9 WRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRLDKDLTIGQMQGKFQMQVLPQ
310 320 330 340 350 360
350 360 370 380
pF1KB9 CGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC
::::::::::::::::::::::::::::::::::::::::
NP_001 CGHAVHEDAPDKVAEAVATFLIRHRFAEPIGGFQCVFPGC
370 380 390 400
>>NP_001243514 (OMIM: 609699) monoglyceride lipase isofo (283 aa)
initn: 125 init1: 73 opt: 155 Z-score: 173.0 bits: 40.3 E(85289): 0.0067
Smith-Waterman score: 155; 27.4% identity (60.3% similar) in 146 aa overlap (31-167:1-143)
10 20 30 40 50
pF1KB9 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGP----GRKRDFSP--VPWSQYFESME
:. :: . .. :: .: : ....
NP_001 METGPEDPSSMPEESSPRRTPQSIPYQDLP
10 20 30
60 70 80 90 100 110
pF1KB9 DVEVENETGKDTF-RVYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDL
.. : :. : : .: .:. .... ::.:. . . . : .. .. . : :
NP_001 --HLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDH
40 50 60 70 80
120 130 140 150 160 170
pF1KB9 RSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLV
.::... . . .....:: . :..: : : :..:.:::::::::. ::.
NP_001 VGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPG
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 PSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSM
NP_001 HFAGMVLISPLVLANPESATTFKVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKL
150 160 170 180 190 200
>>XP_011510679 (OMIM: 609699) PREDICTED: monoglyceride l (339 aa)
initn: 102 init1: 73 opt: 156 Z-score: 172.9 bits: 40.6 E(85289): 0.0068
Smith-Waterman score: 156; 24.6% identity (59.8% similar) in 179 aa overlap (31-199:1-174)
10 20 30 40 50
pF1KB9 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGP----GRKRDFSP--VPWSQYFESME
:. :: . .. :: .: : ....
XP_011 METGPEDPSSMPEESSPRRTPQSIPYQDLP
10 20 30
60 70 80 90 100 110
pF1KB9 DVEVENETGKDTF-RVYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDL
.. : :. : : .: .:. .... ::.:. . . . : .. .. . : :
XP_011 --HLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDH
40 50 60 70 80
120 130 140 150 160 170
pF1KB9 RSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLV
.::... . . .....:: . :..: : : :..:.:::::::::. ::.
XP_011 VGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAER--
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 PS-LLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVS
:. . :. .:. . . .. ...... :
XP_011 PGHFAGMVLISPLVLANPESATTFKDYSRILKHLMEKASRMLKFWIPRPFWVLAAKVLNL
150 160 170 180 190 200
>>NP_009214 (OMIM: 609699) monoglyceride lipase isoform (313 aa)
initn: 125 init1: 73 opt: 155 Z-score: 172.4 bits: 40.4 E(85289): 0.0073
Smith-Waterman score: 155; 27.4% identity (60.3% similar) in 146 aa overlap (31-167:1-143)
10 20 30 40 50
pF1KB9 MSALEKSMHLGRLPSRPPLPGSGGSQSGAKMRMGP----GRKRDFSP--VPWSQYFESME
:. :: . .. :: .: : ....
NP_009 METGPEDPSSMPEESSPRRTPQSIPYQDLP
10 20 30
60 70 80 90 100 110
pF1KB9 DVEVENETGKDTF-RVYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDL
.. : :. : : .: .:. .... ::.:. . . . : .. .. . : :
NP_009 --HLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDH
40 50 60 70 80
120 130 140 150 160 170
pF1KB9 RSHGETKVKNPEDLSAETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLV
.::... . . .....:: . :..: : : :..:.:::::::::. ::.
NP_009 VGHGQSEGERMVVSDFHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPG
90 100 110 120 130 140
180 190 200 210 220 230
pF1KB9 PSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSM
NP_009 HFAGMVLISPLVLANPESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSD
150 160 170 180 190 200
>>XP_016861155 (OMIM: 609699) PREDICTED: monoglyceride l (273 aa)
initn: 125 init1: 73 opt: 153 Z-score: 171.1 bits: 39.9 E(85289): 0.0086
Smith-Waterman score: 153; 28.2% identity (61.8% similar) in 131 aa overlap (42-167:6-133)
20 30 40 50 60
pF1KB9 RLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSP--VPWSQYFESMEDVEVENETGKDTF-R
:: .: : .... .. : :. : :
XP_016 MPEESSPRRTPQSIPYQDLP--HLVNADGQYLFCR
10 20 30
70 80 90 100 110 120
pF1KB9 VYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNPEDLS
.: .:. .... ::.:. . . . : .. .. . : : .::... . .
XP_016 YWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDHVGHGQSEGERMVVSD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 AETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGT
.....:: . :..: : : :..:.:::::::::. ::.
XP_016 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 AMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEG
XP_016 PESATTFKVDIYNSDPLICRAGLKVCFGIQLLNAVSRVERALPKLTVPFLLLQGSADRLC
160 170 180 190 200 210
>>XP_011510680 (OMIM: 609699) PREDICTED: monoglyceride l (329 aa)
initn: 102 init1: 73 opt: 154 Z-score: 170.9 bits: 40.2 E(85289): 0.0088
Smith-Waterman score: 154; 25.0% identity (61.0% similar) in 164 aa overlap (42-199:6-164)
20 30 40 50 60
pF1KB9 RLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSP--VPWSQYFESMEDVEVENETGKDTF-R
:: .: : .... .. : :. : :
XP_011 MPEESSPRRTPQSIPYQDLP--HLVNADGQYLFCR
10 20 30
70 80 90 100 110 120
pF1KB9 VYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNPEDLS
.: .:. .... ::.:. . . . : .. .. . : : .::... . .
XP_011 YWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDHVGHGQSEGERMVVSD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 AETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLVPS-LLGLCMIDVVEG
.....:: . :..: : : :..:.:::::::::. ::. :. . :. .:. .
XP_011 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAER--PGHFAGMVLISPLVL
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 TAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPE
. .. ...... :
XP_011 ANPESATTFKDYSRILKHLMEKASRMLKFWIPRPFWVLAAKVLNLVLPNLSLGPIDSSVL
160 170 180 190 200 210
>>NP_001003794 (OMIM: 609699) monoglyceride lipase isofo (303 aa)
initn: 125 init1: 73 opt: 153 Z-score: 170.4 bits: 39.9 E(85289): 0.0094
Smith-Waterman score: 153; 28.2% identity (61.8% similar) in 131 aa overlap (42-167:6-133)
20 30 40 50 60
pF1KB9 RLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSP--VPWSQYFESMEDVEVENETGKDTF-R
:: .: : .... .. : :. : :
NP_001 MPEESSPRRTPQSIPYQDLP--HLVNADGQYLFCR
10 20 30
70 80 90 100 110 120
pF1KB9 VYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNPEDLS
.: .:. .... ::.:. . . . : .. .. . : : .::... . .
NP_001 YWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDHVGHGQSEGERMVVSD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 AETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGT
.....:: . :..: : : :..:.:::::::::. ::.
NP_001 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 AMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEG
NP_001 PESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQ
160 170 180 190 200 210
>>XP_016861151 (OMIM: 609699) PREDICTED: monoglyceride l (305 aa)
initn: 102 init1: 73 opt: 153 Z-score: 170.4 bits: 39.9 E(85289): 0.0095
Smith-Waterman score: 153; 28.2% identity (61.8% similar) in 131 aa overlap (42-167:6-133)
20 30 40 50 60
pF1KB9 RLPSRPPLPGSGGSQSGAKMRMGPGRKRDFSP--VPWSQYFESMEDVEVENETGKDTF-R
:: .: : .... .. : :. : :
XP_016 MPEESSPRRTPQSIPYQDLP--HLVNADGQYLFCR
10 20 30
70 80 90 100 110 120
pF1KB9 VYK-SGSEGPVLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKVKNPEDLS
.: .:. .... ::.:. . . . : .. .. . : : .::... . .
XP_016 YWKPTGTPKALIFVSHGAGEHSGRYEEL-ARMLMGLDLLVFAHDHVGHGQSEGERMVVSD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB9 AETMAKDVGNVVEAMYGDLPP-PIMLIGHSMGGAIAVHTASSNLVPSLLGLCMIDVVEGT
.....:: . :..: : : :..:.:::::::::. ::.
XP_016 FHVFVRDVLQHVDSMQKDYPGLPVFLLGHSMGGAIAILTAAERPGHFAGMVLISPLVLAN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB9 AMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVSMVGQVKQCEGITSPEG
XP_016 PESATTFKVLAAKVLNLVLPNLSLGPIDSSVLSRNKTEVDIYNSDPLICRAGLKVCFGIQ
160 170 180 190 200 210
386 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 00:07:30 2016 done: Fri Nov 4 00:07:31 2016
Total Scan time: 9.490 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]