Result of FASTA (omim) for
pFN21AB9423
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9423, 217 aa
1>>>pF1KB9423 217 - 217 aa - 217 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0087+/-0.000338; mu= 14.9916+/- 0.021
mean_var=58.7640+/-12.020, 0's: 0 Z-trim(114.4): 14 B-trim: 0 in 0/51
Lambda= 0.167309
statistics sampled from 24140 (24154) to 24140 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.283), width: 16
Scan time: 5.880
The best scores are: opt bits E(85289)
NP_775739 (OMIM: 609282) MOB kinase activator 1B i ( 216) 857 214.9 8.1e-56
XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase ( 221) 857 214.9 8.2e-56
NP_001231695 (OMIM: 609282) MOB kinase activator 1 ( 221) 857 214.9 8.2e-56
XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase ( 240) 857 214.9 8.8e-56
XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase ( 247) 857 214.9 9e-56
NP_001304039 (OMIM: 609281) MOB kinase activator 1 ( 215) 842 211.3 9.9e-55
NP_060691 (OMIM: 609281) MOB kinase activator 1A i ( 216) 841 211.0 1.2e-54
NP_001304040 (OMIM: 609281) MOB kinase activator 1 ( 258) 841 211.1 1.4e-54
NP_001231696 (OMIM: 609282) MOB kinase activator 1 ( 147) 552 141.2 8.5e-34
NP_001304041 (OMIM: 609281) MOB kinase activator 1 ( 138) 534 136.8 1.6e-32
XP_011531250 (OMIM: 609281) PREDICTED: MOB kinase ( 180) 534 136.9 2e-32
NP_001165694 (OMIM: 611969) MOB kinase activator 2 ( 268) 440 114.3 1.9e-25
NP_443731 (OMIM: 611969) MOB kinase activator 2 is ( 237) 438 113.8 2.4e-25
>>NP_775739 (OMIM: 609282) MOB kinase activator 1B isofo (216 aa)
initn: 874 init1: 770 opt: 857 Z-score: 1123.1 bits: 214.9 E(85289): 8.1e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:11-211)
10 20 30 40 50 60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
:::.::... :....:: :.:.:.:..: .::.::.:: :::::.:
NP_775 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
:::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:.:
NP_775 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
:: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. :
NP_775 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQEE
120 130 140 150 160 170
190 200 210
pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
::.:: .::: .::.::.::: .:: ::.:. ..
NP_775 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
180 190 200 210
>>XP_005265766 (OMIM: 609282) PREDICTED: MOB kinase acti (221 aa)
initn: 874 init1: 770 opt: 857 Z-score: 1123.0 bits: 214.9 E(85289): 8.2e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:16-216)
10 20 30 40 50
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLN
:::.::... :....:: :.:.:.:..: .::.::.:: :::::
XP_005 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 DWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRY
.::::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:
XP_005 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 MDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMG
.: :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :.
XP_005 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ
120 130 140 150 160 170
180 190 200 210
pF1KB9 SEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
:::.:: .::: .::.::.::: .:: ::.:. ..
XP_005 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
180 190 200 210 220
>>NP_001231695 (OMIM: 609282) MOB kinase activator 1B is (221 aa)
initn: 874 init1: 770 opt: 857 Z-score: 1123.0 bits: 214.9 E(85289): 8.2e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:16-216)
10 20 30 40 50
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLN
:::.::... :....:: :.:.:.:..: .::.::.:: :::::
NP_001 MEGATDVNESGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLN
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 DWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRY
.::::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:
NP_001 EWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 MDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMG
.: :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :.
NP_001 IDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDPVIQLQ
120 130 140 150 160 170
180 190 200 210
pF1KB9 SEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
:::.:: .::: .::.::.::: .:: ::.:. ..
NP_001 EEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
180 190 200 210 220
>>XP_011530714 (OMIM: 609282) PREDICTED: MOB kinase acti (240 aa)
initn: 874 init1: 770 opt: 857 Z-score: 1122.4 bits: 214.9 E(85289): 8.8e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:35-235)
10 20 30 40
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGL
:::.::... :....:: :.:.:.:..:
XP_011 RVDRGAGQPRRTRWASSLAAEETRSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB9 DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQD
.::.::.:: :::::.::::..:::::..:..::::.: :::.::::::.::::::.: :
XP_011 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB9 EHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVF
...:: :::.:.: :: :.. :...: :::...:.::::::..... ::.:::::.
XP_011 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
130 140 150 160 170 180
170 180 190 200 210
pF1KB9 VHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
.:.: .::: . :. :::.:: .::: .::.::.::: .:: ::.:. ..
XP_011 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
190 200 210 220 230 240
>>XP_016864326 (OMIM: 609282) PREDICTED: MOB kinase acti (247 aa)
initn: 874 init1: 770 opt: 857 Z-score: 1122.2 bits: 214.9 E(85289): 9e-56
Smith-Waterman score: 857; 55.0% identity (86.1% similar) in 202 aa overlap (14-215:42-242)
10 20 30 40
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGL
:::.::... :....:: :.:.:.:..:
XP_016 SFDFPGSGDPFISNPLPATSSWYYSGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
20 30 40 50 60 70
50 60 70 80 90 100
pF1KB9 DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQD
.::.::.:: :::::.::::..:::::..:..::::.: :::.::::::.::::::.: :
XP_016 NLRMAVMLPEGEDLNEWVAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWAD
80 90 100 110 120 130
110 120 130 140 150 160
pF1KB9 EHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVF
...:: :::.:.: :: :.. :...: :::...:.::::::..... ::.:::::.
XP_016 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
140 150 160 170 180 190
170 180 190 200 210
pF1KB9 VHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
.:.: .::: . :. :::.:: .::: .::.::.::: .:: ::.:. ..
XP_016 AHIYHQHFDPVIQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLTSKDR
200 210 220 230 240
>>NP_001304039 (OMIM: 609281) MOB kinase activator 1A is (215 aa)
initn: 858 init1: 754 opt: 842 Z-score: 1103.6 bits: 211.3 E(85289): 9.9e-55
Smith-Waterman score: 842; 52.4% identity (85.1% similar) in 208 aa overlap (9-215:4-210)
10 20 30 40 50
pF1KB9 MSNPFLKQVFNKD-KTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLND
.:... :::.::... :....:: :.:.:.:..: .:: ::.:: :::::.
NP_001 MSFLFSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNE
10 20 30 40 50
60 70 80 90 100 110
pF1KB9 WVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYM
:.::..:::::..:..::::.. ::: ::::::.::.:::.: : ...:: :::.:.
NP_001 WIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB9 DLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGS
: :: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :.
NP_001 DYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQE
120 130 140 150 160 170
180 190 200 210
pF1KB9 EAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
:::.:: .::: .::.::.::: .:: ::.:. ..
NP_001 EAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
180 190 200 210
>>NP_060691 (OMIM: 609281) MOB kinase activator 1A isofo (216 aa)
initn: 858 init1: 754 opt: 841 Z-score: 1102.2 bits: 211.0 E(85289): 1.2e-54
Smith-Waterman score: 841; 53.5% identity (85.1% similar) in 202 aa overlap (14-215:11-211)
10 20 30 40 50 60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
:::.::... :....:: :.:.:.:..: .:: ::.:: :::::.:
NP_060 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEW
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
.::..:::::..:..::::.. ::: ::::::.::.:::.: : ...:: :::.:.:
NP_060 IAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
:: :.. :...: :::...:.::::::..... ::.:::::..:.: .::: . :. :
NP_060 YLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVYAHIYHQHFDSVMQLQEE
120 130 140 150 160 170
190 200 210
pF1KB9 AHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
::.:: .::: .::.::.::: .:: ::.:. ..
NP_060 AHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
180 190 200 210
>>NP_001304040 (OMIM: 609281) MOB kinase activator 1A is (258 aa)
initn: 858 init1: 754 opt: 841 Z-score: 1101.1 bits: 211.1 E(85289): 1.4e-54
Smith-Waterman score: 841; 53.5% identity (85.1% similar) in 202 aa overlap (14-215:53-253)
10 20 30 40
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGL
:::.::... :....:: :.:.:.:..:
NP_001 SRIVLSSSDSAHLLALILTNFSCPRSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-
30 40 50 60 70 80
50 60 70 80 90 100
pF1KB9 DLRLAVQLPPGEDLNDWVAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQD
.:: ::.:: :::::.:.::..:::::..:..::::.. ::: ::::::.::.:::.: :
NP_001 NLRQAVMLPEGEDLNEWIAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWAD
90 100 110 120 130 140
110 120 130 140 150 160
pF1KB9 EHKFRKPTALSAPRYMDLLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVF
...:: :::.:.: :: :.. :...: :::...:.::::::..... ::.:::::.
NP_001 GTNIKKPIKCSAPKYIDYLMTWVQDQLDDETLFPSKIGVPFPKNFMSVAKTILKRLFRVY
150 160 170 180 190 200
170 180 190 200 210
pF1KB9 VHVYIHHFDRIAQMGSEAHVNTCYKHFYYFVKEFGLIDTKELEPLKEMTARMCH
.:.: .::: . :. :::.:: .::: .::.::.::: .:: ::.:. ..
NP_001 AHIYHQHFDSVMQLQEEAHLNTSFKHFIFFVQEFNLIDRRELAPLQELIEKLGSKDR
210 220 230 240 250
>>NP_001231696 (OMIM: 609282) MOB kinase activator 1B is (147 aa)
initn: 569 init1: 465 opt: 552 Z-score: 727.8 bits: 141.2 E(85289): 8.5e-34
Smith-Waterman score: 552; 56.2% identity (87.5% similar) in 128 aa overlap (14-141:11-137)
10 20 30 40 50 60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
:::.::... :....:: :.:.:.:..: .::.::.:: :::::.:
NP_001 MSFLFGSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRMAVMLPEGEDLNEW
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
:::..:::::..:..::::.: :::.::::::.::::::.: : ...:: :::.:.:
NP_001 VAVNTVDFFNQINMLYGTITDFCTEESCPVMSAGPKYEYHWADGTNIKKPIKCSAPKYID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
:: :.. :...: :::...:
NP_001 YLMTWVQDQLDDETLFPSKIGIINFCKGDPS
120 130 140
>>NP_001304041 (OMIM: 609281) MOB kinase activator 1A is (138 aa)
initn: 551 init1: 447 opt: 534 Z-score: 704.7 bits: 136.8 E(85289): 1.6e-32
Smith-Waterman score: 534; 53.9% identity (85.9% similar) in 128 aa overlap (14-141:11-137)
10 20 30 40 50 60
pF1KB9 MSNPFLKQVFNKDKTFRPKRKFEPGTQRFELHKKAQASLNAGLDLRLAVQLPPGEDLNDW
:::.::... :....:: :.:.:.:..: .:: ::.:: :::::.:
NP_001 MSFLFSSRSSKTFKPKKNIPEGSHQYELLKHAEATLGSG-NLRQAVMLPEGEDLNEW
10 20 30 40 50
70 80 90 100 110 120
pF1KB9 VAVHVVDFFNRVNLIYGTISDGCTEQSCPVMSGGPKYEYRWQDEHKFRKPTALSAPRYMD
.::..:::::..:..::::.. ::: ::::::.::.:::.: : ...:: :::.:.:
NP_001 IAVNTVDFFNQINMLYGTITEFCTEASCPVMSAGPRYEYHWADGTNIKKPIKCSAPKYID
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB9 LLMDWIEAQINNEDLFPTNVGTPFPKNFLQTVRKILSRLFRVFVHVYIHHFDRIAQMGSE
:: :.. :...: :::...:
NP_001 YLMTWVQDQLDDETLFPSKIGV
120 130
217 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:18:07 2016 done: Thu Nov 3 23:18:08 2016
Total Scan time: 5.880 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]