Result of FASTA (ccds) for
pFN21AB9339
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB9339, 1264 aa
1>>>pF1KB9339 1264 - 1264 aa - 1264 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.8457+/-0.00103; mu= -1.6815+/- 0.062
mean_var=278.2838+/-56.325, 0's: 0 Z-trim(113.0): 61 B-trim: 408 in 1/53
Lambda= 0.076883
statistics sampled from 13616 (13676) to 13616 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.731), E-opt: 0.2 (0.42), width: 16
Scan time: 6.010
The best scores are: opt bits E(32554)
CCDS78450.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1094) 4267 487.5 7.7e-137
CCDS48048.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1095) 4143 473.8 1.1e-132
CCDS48047.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1077) 4138 473.2 1.5e-132
CCDS45320.1 RASGRF1 gene_id:5923|Hs108|chr15 (1257) 531 73.2 4.8e-12
CCDS10309.1 RASGRF1 gene_id:5923|Hs108|chr15 (1273) 529 73.0 5.7e-12
CCDS42065.1 RASGRF1 gene_id:5923|Hs108|chr15 ( 489) 510 70.6 1.1e-11
>>CCDS78450.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1094 aa)
initn: 4267 init1: 4267 opt: 4267 Z-score: 2570.1 bits: 487.5 E(32554): 7.7e-137
Smith-Waterman score: 6940; 86.6% identity (86.6% similar) in 1264 aa overlap (1-1264:1-1094)
10 20 30 40 50 60
pF1KB9 MSGGLGLRRSPEMSGKIEKADSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MSGGLGLRRSPEMSGKIEKADSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB9 PEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB9 LRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB9 NLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 NLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB9 PASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB9 PALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB9 ESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 ESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQI
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB9 PQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 PQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB9 AASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 AASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVE
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB9 FVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 FVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKN
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB9 KLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLQASCAASSFSSVSHCVQQTKVAFTP
:::::::::::::::::::::::::::::::::::
CCDS78 KLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQL-------------------------
610 620 630
670 680 690 700 710 720
pF1KB9 EDGSAAQGLSVSVSNSFLSRHGSLPVPSYKSVFRSYSQDFVPHHQASVPPFLPPTSSSSP
CCDS78 ------------------------------------------------------------
730 740 750 760 770 780
pF1KB9 HFPPAHQSQSSDLAVPTMAGPPPSTVDGPLSASQESSFHGNTVCLPSETSFTDSSENASE
CCDS78 ------------------------------------------------------------
790 800 810 820 830 840
pF1KB9 EAGEGEYVNLYSSGQSSEELAPSRGEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSP
:::::::::::::::::::::::::::::::::::
CCDS78 -------------------------EPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSP
640 650 660 670
850 860 870 880 890 900
pF1KB9 DALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 DALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLV
680 690 700 710 720 730
910 920 930 940 950 960
pF1KB9 LYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVE
740 750 760 770 780 790
970 980 990 1000 1010 1020
pF1KB9 LTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARP
800 810 820 830 840 850
1030 1040 1050 1060 1070 1080
pF1KB9 GTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 GTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWV
860 870 880 890 900 910
1090 1100 1110 1120 1130 1140
pF1KB9 RSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEG
920 930 940 950 960 970
1150 1160 1170 1180 1190 1200
pF1KB9 LAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 LAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRW
980 990 1000 1010 1020 1030
1210 1220 1230 1240 1250 1260
pF1KB9 QQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 QQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDR
1040 1050 1060 1070 1080 1090
pF1KB9 EEKT
::::
CCDS78 EEKT
>>CCDS48048.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1095 aa)
initn: 4143 init1: 4143 opt: 4143 Z-score: 2495.8 bits: 473.8 E(32554): 1.1e-132
Smith-Waterman score: 6816; 86.3% identity (86.3% similar) in 1246 aa overlap (19-1264:20-1095)
10 20 30 40 50
pF1KB9 MSGGLGLRRSPEMSGKIEKADSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVK
: :::::::::::::::::::::::::::::::::::::::
CCDS48 MGNAIEKQKPLKRSHLYPWKQDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVK
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB9 IPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 IPEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVS
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB9 ALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ALRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB9 ANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ANLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPS
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB9 SPASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 SPASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSP
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB9 PPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PPALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYG
310 320 330 340 350 360
360 370 380 390 400 410
pF1KB9 GESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 GESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQ
370 380 390 400 410 420
420 430 440 450 460 470
pF1KB9 IPQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 IPQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRR
430 440 450 460 470 480
480 490 500 510 520 530
pF1KB9 SAASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 SAASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPV
490 500 510 520 530 540
540 550 560 570 580 590
pF1KB9 EFVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 EFVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQK
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB9 NKLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLQASCAASSFSSVSHCVQQTKVAFT
::::::::::::::::::::::::::::::::::::
CCDS48 NKLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQL------------------------
610 620 630
660 670 680 690 700 710
pF1KB9 PEDGSAAQGLSVSVSNSFLSRHGSLPVPSYKSVFRSYSQDFVPHHQASVPPFLPPTSSSS
CCDS48 ------------------------------------------------------------
720 730 740 750 760 770
pF1KB9 PHFPPAHQSQSSDLAVPTMAGPPPSTVDGPLSASQESSFHGNTVCLPSETSFTDSSENAS
CCDS48 ------------------------------------------------------------
780 790 800 810 820 830
pF1KB9 EEAGEGEYVNLYSSGQSSEELAPSRGEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKS
::::::::::::::::::::::::::::::::::
CCDS48 --------------------------EPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKS
640 650 660 670
840 850 860 870 880 890
pF1KB9 PDALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PDALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDL
680 690 700 710 720 730
900 910 920 930 940 950
pF1KB9 VLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 VLYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLV
740 750 760 770 780 790
960 970 980 990 1000 1010
pF1KB9 ELTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ELTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAAR
800 810 820 830 840 850
1020 1030 1040 1050 1060 1070
pF1KB9 PGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PGTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYW
860 870 880 890 900 910
1080 1090 1100 1110 1120 1130
pF1KB9 VRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 VRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSE
920 930 940 950 960 970
1140 1150 1160 1170 1180 1190
pF1KB9 GLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 GLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKR
980 990 1000 1010 1020 1030
1200 1210 1220 1230 1240 1250
pF1KB9 WQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 WQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTD
1040 1050 1060 1070 1080 1090
1260
pF1KB9 REEKT
:::::
CCDS48 REEKT
>>CCDS48047.1 RAPGEF1 gene_id:2889|Hs108|chr9 (1077 aa)
initn: 4138 init1: 4138 opt: 4138 Z-score: 2492.9 bits: 473.2 E(32554): 1.5e-132
Smith-Waterman score: 6811; 86.3% identity (86.3% similar) in 1244 aa overlap (21-1264:4-1077)
10 20 30 40 50 60
pF1KB9 MSGGLGLRRSPEMSGKIEKADSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKI
::::::::::::::::::::::::::::::::::::::::
CCDS48 MDTDSQRSHLSSFTMKLMDKFHSPKIKRTPSKKGKPAEVSVKI
10 20 30 40
70 80 90 100 110 120
pF1KB9 PEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PEKPVNKEATDRFLPEGYPLPLDLEQQAVEFMSTSAVASRSQRQKNLSWLEEKEKEVVSA
50 60 70 80 90 100
130 140 150 160 170 180
pF1KB9 LRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 LRYFKTIVDKMAIDKKVLEMLPGSASKVLEAILPLVQNDPRIQHSSALSSCYSRVYQSLA
110 120 130 140 150 160
190 200 210 220 230 240
pF1KB9 NLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 NLIRWSDQVMLEGVNSEDKEMVTTVKGVIKAVLDGVKELVRLTIEKQGRPSPTSPVKPSS
170 180 190 200 210 220
250 260 270 280 290 300
pF1KB9 PASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PASKPDGPAELPLTDREVEILNKTTGMSQSTELLPDATDEEVAPPKPPLPGIRVVDNSPP
230 240 250 260 270 280
310 320 330 340 350 360
pF1KB9 PALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PALPPKKRQSAPSPTRVAVVAPMSRATSGSSLPVGINRQDFDVDCYAQRRLSGGSHSYGG
290 300 310 320 330 340
370 380 390 400 410 420
pF1KB9 ESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 ESPRLSPCSSIGKLSKSDEQLSSLDRDSGQCSRNTSCETLDHYDPDYEFLQQDLSNADQI
350 360 370 380 390 400
430 440 450 460 470 480
pF1KB9 PQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 PQQTAWNLSPLPESLGESGSPFLGPPFQLPLGGHPQPDGPLAPGQQTDTPPALPEKKRRS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB9 AASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 AASQTADGSGCRVSYERHPSQYDNISGEDLQSTAPIPSVPYAPFAAILPFQHGGSSAPVE
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB9 FVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 FVGDFTAPESTGDPEKPPPLPEKKNKHMLAYMQLLEDYSEPQPSMFYQTPQNEHIYQQKN
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB9 KLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQLQASCAASSFSSVSHCVQQTKVAFTP
:::::::::::::::::::::::::::::::::::
CCDS48 KLLMEVYGFSDSFSGVDSVQELAPPPALPPKQRQL-------------------------
590 600 610
670 680 690 700 710 720
pF1KB9 EDGSAAQGLSVSVSNSFLSRHGSLPVPSYKSVFRSYSQDFVPHHQASVPPFLPPTSSSSP
CCDS48 ------------------------------------------------------------
730 740 750 760 770 780
pF1KB9 HFPPAHQSQSSDLAVPTMAGPPPSTVDGPLSASQESSFHGNTVCLPSETSFTDSSENASE
CCDS48 ------------------------------------------------------------
790 800 810 820 830 840
pF1KB9 EAGEGEYVNLYSSGQSSEELAPSRGEPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSP
:::::::::::::::::::::::::::::::::::
CCDS48 -------------------------EPPAGKDGHPRDPSAVSGVPGKDSRDGSERAPKSP
620 630 640 650
850 860 870 880 890 900
pF1KB9 DALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 DALESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLV
660 670 680 690 700 710
910 920 930 940 950 960
pF1KB9 LYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 LYCEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDELCLVE
720 730 740 750 760 770
970 980 990 1000 1010 1020
pF1KB9 LTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 LTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARP
780 790 800 810 820 830
1030 1040 1050 1060 1070 1080
pF1KB9 GTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 GTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLLWAKEQNEEKSPNLTQFTEHFNNMSYWV
840 850 860 870 880 890
1090 1100 1110 1120 1130 1140
pF1KB9 RSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 RSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLEWQKQTSEG
900 910 920 930 940 950
1150 1160 1170 1180 1190 1200
pF1KB9 LAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 LAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYIDGKVNFSKRW
960 970 980 990 1000 1010
1210 1220 1230 1240 1250 1260
pF1KB9 QQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS48 QQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDR
1020 1030 1040 1050 1060 1070
pF1KB9 EEKT
::::
CCDS48 EEKT
>>CCDS45320.1 RASGRF1 gene_id:5923|Hs108|chr15 (1257 aa)
initn: 386 init1: 175 opt: 531 Z-score: 329.7 bits: 73.2 E(32554): 4.8e-12
Smith-Waterman score: 542; 27.2% identity (58.3% similar) in 569 aa overlap (707-1251:722-1254)
680 690 700 710 720 730
pF1KB9 FLSRHGSLPVPSYKSVFRSYSQDFVPHHQASVPPFLPPTSSSSPHFPPAHQSQSSDLAVP
: :: : :..::: . .. .: .:
CCDS45 RSLELLFASGQNNKLLYGEPPKSPRATRKFSSPPPLSITKTSSPS-----RRRKLSLNIP
700 710 720 730 740
740 750 760 770 780 790
pF1KB9 TMAGPPPSTVDGPLSASQESSFHGNTVCLPSETSFTDSSENASEEAGEGEYVNLYSSGQS
..: ...: :.: . .: .: : . . :. .. ..:. :: :..
CCDS45 IITGG--KALD--LAALSCNS-NGYTSMYSAMSPFSKATLDTSK---------LYVSSSF
750 760 770 780 790
800 810 820 830 840
pF1KB9 SEELAPSRGEPPAGKDGHPRDPSAVS------------GVPGKDSRDG-SERAP-KSPDA
.... :..:. : :.::::.: . ..: :: .: .: ::: .
CCDS45 TNKI-PDEGDTTPEK---PEDPSALSKQSSEVSMREESDIDQNQSDDGDTETSPTKSPTT
800 810 820 830 840
850 860 870 880 890 900
pF1KB9 LESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLY
.:..... .:. :...:. . . .. .. . ..:. . . ... . :
CCDS45 PKSVKNKNS-SEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEGTPNKEKY
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB9 CEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDEL-C-LVE
. :.. . .. :.. : . ..... :::.. .. ::: : ..
CCDS45 RRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHS--QDFETNDELKCKVIG
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB9 LTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARP
. ::... ::. . .. .. :.: .. : :.. :. :. :.:: :.:
CCDS45 FLEEVMHD-PELLTQER-KAAANIIRTLTQE--DPGDNQITLEEITQ----MAEGVKAEP
970 980 990 1000 1010
1030 1040 1050 1060 1070
pF1KB9 GTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLL--WAKEQNEEKSPNLTQFTEHFNNMSY
... . :::::::::: .: :: : . : : ...:..: . . :.:::..:
CCDS45 --FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISN
1020 1030 1040 1050 1060 1070
1080 1090 1100 1110 1120 1130
pF1KB9 WVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLE--W---
. : :. .: . : . :.. . : :.:.:. : : :... . : ::. :
CCDS45 LIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKV
1080 1090 1100 1110 1120 1130
1140 1150 1160 1170 1180 1190
pF1KB9 QKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYI-DG
.:::. . . :..: . :. : ::.. .:::.::::. : ::.:.. :.:.: ::
CCDS45 SKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDG
1140 1150 1160 1170 1180 1190
1200 1210 1220 1230 1240 1250
pF1KB9 KVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRN
::::: . .:. .: :::. : .... . ... : : . ::.:.: ::.:.:.
CCDS45 LVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKL
1200 1210 1220 1230 1240 1250
1260
pF1KB9 ITRRKTDREEKT
CCDS45 PT
>>CCDS10309.1 RASGRF1 gene_id:5923|Hs108|chr15 (1273 aa)
initn: 386 init1: 175 opt: 529 Z-score: 328.4 bits: 73.0 E(32554): 5.7e-12
Smith-Waterman score: 542; 27.2% identity (58.3% similar) in 569 aa overlap (707-1251:738-1270)
680 690 700 710 720 730
pF1KB9 FLSRHGSLPVPSYKSVFRSYSQDFVPHHQASVPPFLPPTSSSSPHFPPAHQSQSSDLAVP
: :: : :..::: . .. .: .:
CCDS10 RSLELLFASGQNNKLLYGEPPKSPRATRKFSSPPPLSITKTSSPS-----RRRKLSLNIP
710 720 730 740 750 760
740 750 760 770 780 790
pF1KB9 TMAGPPPSTVDGPLSASQESSFHGNTVCLPSETSFTDSSENASEEAGEGEYVNLYSSGQS
..: ...: :.: . .: .: : . . :. .. ..:. :: :..
CCDS10 IITGG--KALD--LAALSCNS-NGYTSMYSAMSPFSKATLDTSK---------LYVSSSF
770 780 790 800
800 810 820 830 840
pF1KB9 SEELAPSRGEPPAGKDGHPRDPSAVS------------GVPGKDSRDG-SERAP-KSPDA
.... :..:. : :.::::.: . ..: :: .: .: ::: .
CCDS10 TNKI-PDEGDTTPEK---PEDPSALSKQSSEVSMREESDIDQNQSDDGDTETSPTKSPTT
810 820 830 840 850 860
850 860 870 880 890 900
pF1KB9 LESAQSEEEVDELSLIDHNEIMSRLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLY
.:..... .:. :...:. . . .. .. . ..:. . . ... . :
CCDS10 PKSVKNKNS-SEFPLFSYNNGVVMTSCRELDNNRSALSAASAFAIATAGANEGTPNKEKY
870 880 890 900 910 920
910 920 930 940 950 960
pF1KB9 CEAFLTTYRTFISPEELIKKLQYRYEKFSPFADTFKKRVSKNTFFVLVRVVDEL-C-LVE
. :.. . .. :.. : . ..... :::.. .. ::: : ..
CCDS10 RRMSLASAGFPPDQRNGDKEFVIRRAATNRVLNVLRHWVSKHS--QDFETNDELKCKVIG
930 940 950 960 970 980
970 980 990 1000 1010 1020
pF1KB9 LTEEILKLLMELVFRLVCNGELSLARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARP
. ::... ::. . .. .. :.: .. : :.. :. :. :.:: :.:
CCDS10 FLEEVMHD-PELLTQER-KAAANIIRTLTQE--DPGDNQITLEEITQ----MAEGVKAEP
990 1000 1010 1020 1030
1030 1040 1050 1060 1070
pF1KB9 GTLHDFHSHEIAEQLTLLDAELFYKIEIPEVLL--WAKEQNEEKSPNLTQFTEHFNNMSY
... . :::::::::: .: :: : . : : ...:..: . . :.:::..:
CCDS10 --FENHSALEIAEQLTLLDHLVFKKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISN
1040 1050 1060 1070 1080 1090
1080 1090 1100 1110 1120 1130
pF1KB9 WVRSIIMLQEKAQDRERLLLKFIKIMKHLRKLNNFNSYLAILSALDSAPIRRLE--W---
. : :. .: . : . :.. . : :.:.:. : : :... . : ::. :
CCDS10 LIASEIIRNEDINARVSAIEKWVAVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKV
1100 1110 1120 1130 1140 1150
1140 1150 1160 1170 1180 1190
pF1KB9 QKQTSEGLAEYCTLIDSSSSFRAYRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYI-DG
.:::. . . :..: . :. : ::.. .:::.::::. : ::.:.. :.:.: ::
CCDS10 SKQTKALIDKLQKLVSSEGRFKNLREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDG
1160 1170 1180 1190 1200 1210
1200 1210 1220 1230 1240 1250
pF1KB9 KVNFSKRWQQFNILDSMRCFQQAHYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRN
::::: . .:. .: :::. : .... . ... : : . ::.:.: ::.:.:.
CCDS10 LVNFSKMRMISHIIREIRQFQQTAYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKL
1220 1230 1240 1250 1260 1270
1260
pF1KB9 ITRRKTDREEKT
CCDS10 PT
>>CCDS42065.1 RASGRF1 gene_id:5923|Hs108|chr15 (489 aa)
initn: 350 init1: 175 opt: 510 Z-score: 323.2 bits: 70.6 E(32554): 1.1e-11
Smith-Waterman score: 518; 28.0% identity (59.5% similar) in 486 aa overlap (790-1251:18-486)
760 770 780 790 800 810
pF1KB9 GNTVCLPSETSFTDSSENASEEAGEGEYVNLYSSGQSSEELAPSRGEPPAGKDGHPRDPS
:: :.. .... :..:. : :.:::
CCDS42 MYSAMSPFSKATLDTSKLYVSSSFTNKI-PDEGDTTPEK---PEDPS
10 20 30 40
820 830 840 850 860
pF1KB9 AVS------------GVPGKDSRDG-SERAP-KSPDALESAQSEEEVDELSLIDHNEIMS
:.: . ..: :: .: .: ::: . .:..... .:. :...:. .
CCDS42 ALSKQSSEVSMREESDIDQNQSDDGDTETSPTKSPTTPKSVKNKNS-SEFPLFSYNNGVV
50 60 70 80 90 100
870 880 890 900 910 920
pF1KB9 RLTLKQEGDDGPDVRGGSGDILLVHATETDRKDLVLYCEAFLTTYRTFISPEELIKKLQY
. .. .. . ..:. . . ... . : . :.. . .. :..
CCDS42 MTSCRELDNNRSALSAASAFAIATAGANEGTPNKEKYRRMSLASAGFPPDQRNGDKEFVI
110 120 130 140 150 160
930 940 950 960 970 980
pF1KB9 RYEKFSPFADTFKKRVSKNTFFVLVRVVDEL-C-LVELTEEILKLLMELVFRLVCNGELS
: . ..... :::.. .. ::: : .. . ::... ::. . .. .
CCDS42 RRAATNRVLNVLRHWVSKHS--QDFETNDELKCKVIGFLEEVMHD-PELLTQER-KAAAN
170 180 190 200 210
990 1000 1010 1020 1030 1040
pF1KB9 LARVLRKNILDKVDQKKLLRCATSSQPLAARGVAARPGTLHDFHSHEIAEQLTLLDAELF
. :.: .. : :.. :. :. :.:: :.: ... . :::::::::: .:
CCDS42 IIRTLTQE--DPGDNQITLEEITQ----MAEGVKAEP--FENHSALEIAEQLTLLDHLVF
220 230 240 250 260 270
1050 1060 1070 1080 1090 1100
pF1KB9 YKIEIPEVLL--WAKEQNEEKSPNLTQFTEHFNNMSYWVRSIIMLQEKAQDRERLLLKFI
:: : . : : ...:..: . . :.:::..: . : :. .: . : . :..
CCDS42 KKIPYEEFFGQGWMKLEKNERTPYIMKTTKHFNDISNLIASEIIRNEDINARVSAIEKWV
280 290 300 310 320 330
1110 1120 1130 1140 1150
pF1KB9 KIMKHLRKLNNFNSYLAILSALDSAPIRRLE--W---QKQTSEGLAEYCTLIDSSSSFRA
. : :.:.:. : : :... . : ::. : .:::. . . :..: . :.
CCDS42 AVADICRCLHNYNAVLEITSSMNRSAIFRLKKTWLKVSKQTKALIDKLQKLVSSEGRFKN
340 350 360 370 380 390
1160 1170 1180 1190 1200 1210
pF1KB9 YRAALSEVEPPCIPYLGLILQDLTFVHLGNPDYI-DGKVNFSKRWQQFNILDSMRCFQQA
: ::.. .:::.::::. : ::.:.. :.:.: :: ::::: . .:. .: :::.
CCDS42 LREALKNCDPPCVPYLGMYLTDLAFIEEGTPNYTEDGLVNFSKMRMISHIIREIRQFQQT
400 410 420 430 440 450
1220 1230 1240 1250 1260
pF1KB9 HYDMRRNDDIINFFNDFSDHLAEEALWELSLKIKPRNITRRKTDREEKT
: .... . ... : : . ::.:.: ::.:.:.
CCDS42 AYKIEHQAKVTQYLLDQSFVMDEESLYESSLRIEPKLPT
460 470 480
1264 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 23:09:05 2016 done: Thu Nov 3 23:09:06 2016
Total Scan time: 6.010 Total Display time: 0.250
Function used was FASTA [36.3.4 Apr, 2011]