Result of FASTA (omim) for
pFN21AB5281
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5281, 272 aa
1>>>pF1KB5281 272 - 272 aa - 272 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7788+/-0.000268; mu= 2.4569+/- 0.017
mean_var=222.8349+/-44.393, 0's: 0 Z-trim(126.5): 25 B-trim: 85 in 1/61
Lambda= 0.085918
statistics sampled from 52735 (52767) to 52735 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.864), E-opt: 0.2 (0.619), width: 16
Scan time: 9.830
The best scores are: opt bits E(85289)
NP_620450 (OMIM: 606385) oligodendrocyte transcrip ( 271) 1786 232.7 5.7e-61
XP_005260965 (OMIM: 606386) PREDICTED: oligodendro ( 323) 317 50.6 4.2e-06
NP_005797 (OMIM: 606386) oligodendrocyte transcrip ( 323) 317 50.6 4.2e-06
NP_786923 (OMIM: 609323) oligodendrocyte transcrip ( 272) 310 49.7 6.8e-06
NP_542173 (OMIM: 609331) class E basic helix-loop- ( 241) 296 47.9 2.1e-05
NP_689627 (OMIM: 613483) class E basic helix-loop- ( 381) 291 47.5 4.5e-05
NP_803238 (OMIM: 608606) class A basic helix-loop- ( 189) 227 39.3 0.0065
>>NP_620450 (OMIM: 606385) oligodendrocyte transcription (271 aa)
initn: 1522 init1: 1522 opt: 1786 Z-score: 1215.6 bits: 232.7 E(85289): 5.7e-61
Smith-Waterman score: 1786; 99.6% identity (99.6% similar) in 272 aa overlap (1-272:1-271)
10 20 30 40 50 60
pF1KB5 MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSS
:::::::::::::::::::::::::::::::::::::::::::::::: :::::::::::
NP_620 MYYAVSQARVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSS-TSSTSSTSSSS
10 20 30 40 50
70 80 90 100 110 120
pF1KB5 TTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 DLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 DLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELRRALGEGA
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB5 GPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGA
180 190 200 210 220 230
250 260 270
pF1KB5 GGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
::::::::::::::::::::::::::::::::
NP_620 GGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
240 250 260 270
>>XP_005260965 (OMIM: 606386) PREDICTED: oligodendrocyte (323 aa)
initn: 385 init1: 159 opt: 317 Z-score: 230.5 bits: 50.6 E(85289): 4.2e-06
Smith-Waterman score: 355; 36.6% identity (51.0% similar) in 290 aa overlap (42-254:23-301)
20 30 40 50 60 70
pF1KB5 AVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSSTTAPLLPKAAR
:. :..:: :. .. . ::.: :
XP_005 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCP----
10 20 30 40
80 90 100
pF1KB5 EKPEAPAEPPGPGPGSGAHPG------------------------GSARPDAK---EEQQ
:: :: : ..::::: .:.. : : : .
XP_005 --PELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPEL
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB5 QQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILL
:::: ::::::::::.:::.:::.:::: .:: :: : :::::::::::::::::.
XP_005 QQLRLKINSRERKRMHDLNIAMDGLREV-MPY--AH--GPSVRKLSKIATLLLARNYILM
110 120 130 140 150 160
170 180 190 200
pF1KB5 LGSSLQELRRAL-----GEGAG--PAAPRLLLAGLPLLAAA--PGSV------------L
: .::.:..: . :. :: :.: : . :: ::. :... .
XP_005 LTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPI
170 180 190 200 210 220
210 220 230 240
pF1KB5 LAPGAVGPPDALRPAKYLSLALD----------EPPCGQFALP--------GGGAGGPGL
: :.:.. : : : .: .:: : . : :::.:: :
XP_005 LPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGA
230 240 250 260 270 280
250 260 270
pF1KB5 -----------CTCAVCKFPHLVPASLGLAAVQAQFSK
: :..:. :
XP_005 SGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK
290 300 310 320
>>NP_005797 (OMIM: 606386) oligodendrocyte transcription (323 aa)
initn: 385 init1: 159 opt: 317 Z-score: 230.5 bits: 50.6 E(85289): 4.2e-06
Smith-Waterman score: 355; 36.6% identity (51.0% similar) in 290 aa overlap (42-254:23-301)
20 30 40 50 60 70
pF1KB5 AVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSSTTAPLLPKAAR
:. :..:: :. .. . ::.: :
NP_005 MDSDASLVSSRPSSPEPDDLFLPARSKGSSGSAFTGGTVSSSTPSDCP----
10 20 30 40
80 90 100
pF1KB5 EKPEAPAEPPGPGPGSGAHPG------------------------GSARPDAK---EEQQ
:: :: : ..::::: .:.. : : : .
NP_005 --PELSAELRGAMGSAGAHPGDKLGGSGFKSSSSSTSSSTSSAAASSTKKDKKQMTEPEL
50 60 70 80 90 100
110 120 130 140 150 160
pF1KB5 QQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILL
:::: ::::::::::.:::.:::.:::: .:: :: : :::::::::::::::::.
NP_005 QQLRLKINSRERKRMHDLNIAMDGLREV-MPY--AH--GPSVRKLSKIATLLLARNYILM
110 120 130 140 150 160
170 180 190 200
pF1KB5 LGSSLQELRRAL-----GEGAG--PAAPRLLLAGLPLLAAA--PGSV------------L
: .::.:..: . :. :: :.: : . :: ::. :... .
NP_005 LTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAATAHPAAAAHAAHHPAVHHPI
170 180 190 200 210 220
210 220 230 240
pF1KB5 LAPGAVGPPDALRPAKYLSLALD----------EPPCGQFALP--------GGGAGGPGL
: :.:.. : : : .: .:: : . : :::.:: :
NP_005 LPPAAAAAAAAAAAAAVSSASLPGSGLPSVGSIRPPHGLLKSPSAAAAAPLGGGGGGSGA
230 240 250 260 270 280
250 260 270
pF1KB5 -----------CTCAVCKFPHLVPASLGLAAVQAQFSK
: :..:. :
NP_005 SGGFQHWGGMPCPCSMCQVPPPHHHVSAMGAGSLPRLTSDAK
290 300 310 320
>>NP_786923 (OMIM: 609323) oligodendrocyte transcription (272 aa)
initn: 334 init1: 158 opt: 310 Z-score: 226.8 bits: 49.7 E(85289): 6.8e-06
Smith-Waterman score: 349; 42.3% identity (57.7% similar) in 227 aa overlap (83-272:52-268)
60 70 80 90 100
pF1KB5 TSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPG---SGAHPGG-SARPDAK----EEQQ
:: . .::. .: :.. : :..
NP_786 LRDHHHRHHHHQESRLNSVSSTQGDMMQKMPGESLSRAGAKAAGESSKYKIKKQLSEQDL
30 40 50 60 70 80
110 120 130 140 150 160
pF1KB5 QQLRRKINSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILL
:::: :::.::::::.:::::::.:::: .:: :: : :::::::::::::::::.
NP_786 QQLRLKINGRERKRMHDLNLAMDGLREV-MPY--AH--GPSVRKLSKIATLLLARNYILM
90 100 110 120 130
170 180 190 200 210
pF1KB5 LGSSLQELRRALGEGAGPAAPRLLL------AGLPLLAAA---P-----GSVLLAPGAVG
: :::.:..: .:: : . :: : :: : :..: . .: .
NP_786 LTSSLEEMKRLVGEIYGGHHSAFHCGTVGHSAGHPAHAANSVHPVHPILGGALSSGNASS
140 150 160 170 180 190
220 230 240 250
pF1KB5 PPDA--------LRPAKYLSLALDEPPCGQFALPGGG----AGGPGLCTCAVCKFP---H
: .: .:: . : : . :: :. :.: :: : : :..:..: :
NP_786 PLSAASLPAIGTIRPPHSLLKAPSTPPALQL---GSGFQHWAGLP--CPCTICQMPPPPH
200 210 220 230 240 250
260 270
pF1KB5 LVPASLGLAAVQAQFSK
: : . : . ::
NP_786 LSALSTANMARLSAESKDLLK
260 270
>>NP_542173 (OMIM: 609331) class E basic helix-loop-heli (241 aa)
initn: 290 init1: 141 opt: 296 Z-score: 218.1 bits: 47.9 E(85289): 2.1e-05
Smith-Waterman score: 296; 48.5% identity (70.6% similar) in 136 aa overlap (84-213:100-221)
60 70 80 90 100 110
pF1KB5 SSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINS
::::.: : :: ..:..:: .::.
NP_542 APRAPAQAAESSGEQSGDEDDAFEQRRRRRGPGSAAD--GRRRP----REQRSLRLSINA
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB5 RERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELR
:::.::.::: :.:.:: :: :: :: .. ::::::::::::.::::. ...:.:.:
NP_542 RERRRMHDLNDALDGLRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALDEMR
130 140 150 160 170
180 190 200 210 220
pF1KB5 RA---LGEGAGPAAPRLLLAGLPLLAAAPGSV--LLAPGAVGP-PDALRPAKYLSLALDE
: :..: : ::: . . :: . ..: . : .:.:: ::
NP_542 RLVAFLNQGQGLAAP---VNAAPLTPFGQATVCPFSAGAALGPCPDKCAAFSGTPSALCK
180 190 200 210 220 230
230 240 250 260 270
pF1KB5 PPCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
NP_542 HCHEKP
240
>>NP_689627 (OMIM: 613483) class E basic helix-loop-heli (381 aa)
initn: 274 init1: 164 opt: 291 Z-score: 212.1 bits: 47.5 E(85289): 4.5e-05
Smith-Waterman score: 293; 43.0% identity (65.6% similar) in 151 aa overlap (82-229:218-355)
60 70 80 90 100 110
pF1KB5 STSSTSSSSTTAPLLPKAAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKI
: : :::. ..:. . : ..:. :: .:
NP_689 HLHGGASVPPGGLGGGGGGGSSSGSSGGGGGSGSGSGGSSSSSSSSSKKSKEQKALRLNI
190 200 210 220 230 240
120 130 140 150 160 170
pF1KB5 NSRERKRMQDLNLAMDALREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQE
:.:::.::.::: :.: :: :: :: :: .. ::::::::::::.::::. ...:.:
NP_689 NARERRRMHDLNDALDELRAVI-PY--AHSPSV--RKLSKIATLLLAKNYILMQAQALEE
250 260 270 280 290 300
180 190 200 210 220
pF1KB5 LRRA---LGEGAGPAAPRLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEP
.:: :..: . .: :.:: ::: ... :.: : . : .. :
NP_689 MRRLVAYLNQGQAISA-----ASLPSSAAAAAAAAALHPALG---AYEQAAGYPFSAGLP
310 320 330 340 350
230 240 250 260 270
pF1KB5 PCGQFALPGGGAGGPGLCTCAVCKFPHLVPASLGLAAVQAQFSK
:
NP_689 PAASCPEKCALFNSVSSSLCKQCTEKP
360 370 380
>>NP_803238 (OMIM: 608606) class A basic helix-loop-heli (189 aa)
initn: 236 init1: 88 opt: 227 Z-score: 173.3 bits: 39.3 E(85289): 0.0065
Smith-Waterman score: 227; 36.7% identity (59.9% similar) in 147 aa overlap (39-182:10-147)
10 20 30 40 50 60
pF1KB5 RVNAVPGTMLRPQRPGDLQLGASLYELVGYRQPPSSSSSSSTSSTSSTSSSSTTAPLLPK
:. : ... .. . . .: . .: :
NP_803 MKTKNRPPRRRAPVQDTEATPGEGTPDGSLPNPGPEPAK
10 20 30
70 80 90 100 110 120
pF1KB5 AAREKPEAPAEPPGPGPGSGAHPGGSARPDAKEEQQQQLRRKINSRERKRMQDLNLAMDA
. : .: : : .:: : .:: :. : ...... : : . : :::.::. :: :..:
NP_803 GLRSRP-ARAAARAPGEGRRRRPGPSG-PGGRRDSSIQRRLESNERERQRMHKLNNAFQA
40 50 60 70 80 90
130 140 150 160 170 180
pF1KB5 LREVILPYSAAHCQGAPGRKLSKIATLLLARNYILLLGSSLQELR--RALG-EGAGPAAP
::::: :. : .::::: :: ::.::: : ... . : : :: ::
NP_803 LREVI-PHVRAD------KKLSKIETLTLAKNYIKSLTATILTMSSSRLPGLEGPGPKLY
100 110 120 130 140 150
190 200 210 220 230 240
pF1KB5 RLLLAGLPLLAAAPGSVLLAPGAVGPPDALRPAKYLSLALDEPPCGQFALPGGGAGGPGL
NP_803 QHYQQQQQVAGGALGATEAQPQGHLQRYSTQIHSFREGT
160 170 180
272 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:25:58 2016 done: Thu Nov 3 22:25:59 2016
Total Scan time: 9.830 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]