Result of FASTA (omim) for
pFN21AB5025
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5025, 239 aa
1>>>pF1KB5025 239 - 239 aa - 239 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.1522+/-0.000326; mu= 9.8141+/- 0.021
mean_var=168.3649+/-33.597, 0's: 0 Z-trim(122.5): 42 B-trim: 1401 in 2/56
Lambda= 0.098844
statistics sampled from 40709 (40759) to 40709 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.478), width: 16
Scan time: 7.890
The best scores are: opt bits E(85289)
NP_079478 (OMIM: 611617) EF-hand domain-containing ( 239) 1543 230.7 1.7e-60
NP_077305 (OMIM: 616450) EF-hand domain-containing ( 240) 972 149.3 5.5e-36
NP_001230181 (OMIM: 611617) EF-hand domain-contain ( 143) 867 134.1 1.2e-31
XP_011510226 (OMIM: 611617) PREDICTED: EF-hand dom ( 127) 789 123.0 2.5e-28
NP_001295324 (OMIM: 611617) EF-hand domain-contain ( 127) 789 123.0 2.5e-28
XP_005246057 (OMIM: 616450) PREDICTED: EF-hand dom ( 195) 587 94.3 1.6e-19
>>NP_079478 (OMIM: 611617) EF-hand domain-containing pro (239 aa)
initn: 1543 init1: 1543 opt: 1543 Z-score: 1207.2 bits: 230.7 E(85289): 1.7e-60
Smith-Waterman score: 1543; 100.0% identity (100.0% similar) in 239 aa overlap (1-239:1-239)
10 20 30 40 50 60
pF1KB5 MASEELACKLERRLRREEAEESGPQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MASEELACKLERRLRREEAEESGPQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 RRLDINEGAARPRRCRVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 RRLDINEGAARPRRCRVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMME
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 KLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 KLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDV
130 140 150 160 170 180
190 200 210 220 230
pF1KB5 ALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 ALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
190 200 210 220 230
>>NP_077305 (OMIM: 616450) EF-hand domain-containing pro (240 aa)
initn: 1025 init1: 834 opt: 972 Z-score: 767.1 bits: 149.3 E(85289): 5.5e-36
Smith-Waterman score: 972; 66.4% identity (83.8% similar) in 241 aa overlap (1-237:1-239)
10 20 30 40 50
pF1KB5 MASEELACKLERRLRREEAEESG--PQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQ
::..::: :: :::. : .: .: :. :.. : :. :.: .::: ::::.
NP_077 MATDELATKLSRRLQME-GEGGGETPEQPGLNGAAAAAAGAPDEAAEA-LGSADCELSAK
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 LSRRLDINEGAARPRRC--RVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELK
: :: :.:.: ..:. ::::::::: ::::. :::.:.::: :::::::::::::::
NP_077 LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 LMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLS
::::::::::::::::.::::::::::.:::::::::::.::::::::::::: .::.::
NP_077 LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQEDSGLCVLARLS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB5 EIDVALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKAN
::::. :::::::.::::::::.. .:.:: :.::::.:::.. :: . :.:::..:...
NP_077 EIDVSSEGVKGAKSFFEAKVQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
180 190 200 210 220 230
pF1KB5 FNT
:
NP_077 FK
240
>>NP_001230181 (OMIM: 611617) EF-hand domain-containing (143 aa)
initn: 867 init1: 867 opt: 867 Z-score: 689.0 bits: 134.1 E(85289): 1.2e-31
Smith-Waterman score: 867; 100.0% identity (100.0% similar) in 138 aa overlap (102-239:6-143)
80 90 100 110 120 130
pF1KB5 PRRCRVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGL
::::::::::::::::::::::::::::::
NP_001 MGELQYDAGRDGFIDLMELKLMMEKLGAPQTHLGL
10 20 30
140 150 160 170 180 190
pF1KB5 KSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNF
40 50 60 70 80 90
200 210 220 230
pF1KB5 FEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
100 110 120 130 140
>>XP_011510226 (OMIM: 611617) PREDICTED: EF-hand domain- (127 aa)
initn: 789 init1: 789 opt: 789 Z-score: 629.6 bits: 123.0 E(85289): 2.5e-28
Smith-Waterman score: 789; 100.0% identity (100.0% similar) in 127 aa overlap (113-239:1-127)
90 100 110 120 130 140
pF1KB5 EFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDF
::::::::::::::::::::::::::::::
XP_011 MELKLMMEKLGAPQTHLGLKSMIKEVDEDF
10 20 30
150 160 170 180 190 200
pF1KB5 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
40 50 60 70 80 90
210 220 230
pF1KB5 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
:::::::::::::::::::::::::::::::::::::
XP_011 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
100 110 120
>>NP_001295324 (OMIM: 611617) EF-hand domain-containing (127 aa)
initn: 789 init1: 789 opt: 789 Z-score: 629.6 bits: 123.0 E(85289): 2.5e-28
Smith-Waterman score: 789; 100.0% identity (100.0% similar) in 127 aa overlap (113-239:1-127)
90 100 110 120 130 140
pF1KB5 EFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKSMIKEVDEDF
::::::::::::::::::::::::::::::
NP_001 MELKLMMEKLGAPQTHLGLKSMIKEVDEDF
10 20 30
150 160 170 180 190 200
pF1KB5 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DGKLSFREFLLIFHKAAAGELQEDSGLMALAKLSEIDVALEGVKGAKNFFEAKVQALSSA
40 50 60 70 80 90
210 220 230
pF1KB5 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
:::::::::::::::::::::::::::::::::::::
NP_001 SKFEAELKAEQDERKREEEERRLRQAAFQKLKANFNT
100 110 120
>>XP_005246057 (OMIM: 616450) PREDICTED: EF-hand domain- (195 aa)
initn: 757 init1: 449 opt: 587 Z-score: 471.5 bits: 94.3 E(85289): 1.6e-19
Smith-Waterman score: 641; 50.6% identity (66.0% similar) in 241 aa overlap (1-237:1-194)
10 20 30 40 50
pF1KB5 MASEELACKLERRLRREEAEESG--PQLAPLGAPAPEPKPEPEPPARAPTASADAELSAQ
::..::: :: :::. : .: .: :. :.. : :. :.: .::: ::::.
XP_005 MATDELATKLSRRLQME-GEGGGETPEQPGLNGAAAAAAGAPDEAAEA-LGSADCELSAK
10 20 30 40 50
60 70 80 90 100 110
pF1KB5 LSRRLDINEGAARPRRC--RVFNPYTEFPEFSRRLIKDLESMFKLYDAGRDGFIDLMELK
: :: :.:.: ..:. ::::::::: ::::. :::.:.::: :::::::::::::::
XP_005 LLRRADLNQGIGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELK
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB5 LMMEKLGAPQTHLGLKSMIKEVDEDFDGKLSFREFLLIFHKAAAGELQEDSGLMALAKLS
::::::::::::::::.::::::::::.::::::
XP_005 LMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFRE--------------------------
120 130 140 150
180 190 200 210 220 230
pF1KB5 EIDVALEGVKGAKNFFEAKVQALSSASKFEAELKAEQDERKREEEERRLRQAAFQKLKAN
:::.. .:.:: :.::::.:::.. :: . :.:::..:...
XP_005 -------------------VQAINVSSRFEEEIKAEQEERKKQAEEMKQRKAAFKELQST
160 170 180 190
pF1KB5 FNT
:
XP_005 FK
239 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 22:13:50 2016 done: Thu Nov 3 22:13:51 2016
Total Scan time: 7.890 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]