Result of FASTA (omim) for
pFN21AB4171
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4171, 1151 aa
1>>>pF1KB4171 1151 - 1151 aa - 1151 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.7310+/-0.000542; mu= -22.9035+/- 0.034
mean_var=766.3066+/-161.206, 0's: 0 Z-trim(124.0): 38 B-trim: 889 in 1/59
Lambda= 0.046331
statistics sampled from 44847 (44891) to 44847 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.777), E-opt: 0.2 (0.526), width: 16
Scan time: 12.680
The best scores are: opt bits E(85289)
XP_005269161 (OMIM: 601734) PREDICTED: SWI/SNF com (1151) 7744 533.8 2.2e-150
NP_001123892 (OMIM: 601734) SWI/SNF complex subuni (1152) 7732 533.0 3.9e-150
XP_005269159 (OMIM: 601734) PREDICTED: SWI/SNF com (1244) 7451 514.3 1.9e-144
NP_001317217 (OMIM: 601734) SWI/SNF complex subuni (1245) 7439 513.5 3.3e-144
NP_620706 (OMIM: 601734) SWI/SNF complex subunit S (1130) 7433 513.0 4e-144
XP_016875373 (OMIM: 601734) PREDICTED: SWI/SNF com (1129) 7432 513.0 4.2e-144
XP_011536995 (OMIM: 601734) PREDICTED: SWI/SNF com ( 994) 5707 397.6 2e-109
NP_003066 (OMIM: 601734) SWI/SNF complex subunit S (1214) 3970 281.6 2e-74
XP_005269160 (OMIM: 601734) PREDICTED: SWI/SNF com (1213) 3964 281.2 2.7e-74
XP_016875375 (OMIM: 601734) PREDICTED: SWI/SNF com (1099) 3933 279.1 1e-73
XP_016875374 (OMIM: 601734) PREDICTED: SWI/SNF com (1121) 3852 273.7 4.5e-72
XP_016875376 (OMIM: 601734) PREDICTED: SWI/SNF com ( 963) 3511 250.8 2.9e-65
NP_003065 (OMIM: 601732) SWI/SNF complex subunit S (1105) 2810 204.0 4.1e-51
XP_011532336 (OMIM: 601732) PREDICTED: SWI/SNF com ( 996) 2429 178.5 1.8e-43
>>XP_005269161 (OMIM: 601734) PREDICTED: SWI/SNF complex (1151 aa)
initn: 7744 init1: 7744 opt: 7744 Z-score: 2820.7 bits: 533.8 E(85289): 2.2e-150
Smith-Waterman score: 7744; 100.0% identity (100.0% similar) in 1151 aa overlap (1-1151:1-1151)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
1090 1100 1110 1120 1130 1140
1150
pF1KB4 PGTVTPVPPPQ
:::::::::::
XP_005 PGTVTPVPPPQ
1150
>>NP_001123892 (OMIM: 601734) SWI/SNF complex subunit SM (1152 aa)
initn: 4089 init1: 3971 opt: 7732 Z-score: 2816.3 bits: 533.0 E(85289): 3.9e-150
Smith-Waterman score: 7732; 99.9% identity (99.9% similar) in 1152 aa overlap (1-1151:1-1152)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL-TSASQQMLNFPDKGKEKP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_001 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB4 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB4 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB4 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB4 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP
1090 1100 1110 1120 1130 1140
1140 1150
pF1KB4 SPGTVTPVPPPQ
::::::::::::
NP_001 SPGTVTPVPPPQ
1150
>>XP_005269159 (OMIM: 601734) PREDICTED: SWI/SNF complex (1244 aa)
initn: 7522 init1: 7422 opt: 7451 Z-score: 2714.4 bits: 514.3 E(85289): 1.9e-144
Smith-Waterman score: 7451; 97.1% identity (98.0% similar) in 1149 aa overlap (1-1149:1-1144)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
::::::::::::::::::::::::...: .. : .: : : : . .: : :
XP_005 FPNQQTPPSMMPGAVPGSGHPGVAGNAP--LGLPFG--MPPPPPPPAP-SIIPFGSLADS
1090 1100 1110 1120 1130
1150
pF1KB4 PGTVTPVPPPQ
. :.::
XP_005 ISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGS
1140 1150 1160 1170 1180 1190
>>NP_001317217 (OMIM: 601734) SWI/SNF complex subunit SM (1245 aa)
initn: 7521 init1: 3971 opt: 7439 Z-score: 2710.1 bits: 513.5 E(85289): 3.3e-144
Smith-Waterman score: 7439; 97.0% identity (97.9% similar) in 1150 aa overlap (1-1149:1-1145)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL-TSASQQMLNFPDKGKEKP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_001 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB4 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB4 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB4 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB4 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP
:::::::::::::::::::::::::...: .. : .: : : : . .: :
NP_001 PFPNQQTPPSMMPGAVPGSGHPGVAGNAP--LGLPFG--MPPPPPPPAP-SIIPFGSLAD
1090 1100 1110 1120 1130
1140 1150
pF1KB4 SPGTVTPVPPPQ
: . :.::
NP_001 SISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLG
1140 1150 1160 1170 1180 1190
>>NP_620706 (OMIM: 601734) SWI/SNF complex subunit SMARC (1130 aa)
initn: 4251 init1: 3971 opt: 7433 Z-score: 2708.4 bits: 513.0 E(85289): 4e-144
Smith-Waterman score: 7539; 98.0% identity (98.0% similar) in 1152 aa overlap (1-1151:1-1130)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL-TSASQQMLNFPDKGKEKP
::::::::::::::::::::::::::::::::::::::::: ::::::::::::::::::
NP_620 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELQTSASQQMLNFPDKGKEKP
550 560 570 580 590 600
600 610 620 630 640 650
pF1KB4 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGS
610 620 630 640 650 660
660 670 680 690 700 710
pF1KB4 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVA
670 680 690 700 710 720
720 730 740 750 760 770
pF1KB4 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPE
730 740 750 760 770 780
780 790 800 810 820 830
pF1KB4 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKE
790 800 810 820 830 840
840 850 860 870 880 890
pF1KB4 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAA
850 860 870 880 890 900
900 910 920 930 940 950
pF1KB4 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLA
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KB4 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 DRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVA
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KB4 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPS
1030 1040 1050 1060 1070 1080
1080 1090 1100 1110 1120 1130
pF1KB4 PFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAP
::::::::::::::::::::::::: :::::::::::::
NP_620 PFPNQQTPPSMMPGAVPGSGHPGVA----------------------DPGTPLPPDPTAP
1090 1100 1110
1140 1150
pF1KB4 SPGTVTPVPPPQ
::::::::::::
NP_620 SPGTVTPVPPPQ
1120 1130
>>XP_016875373 (OMIM: 601734) PREDICTED: SWI/SNF complex (1129 aa)
initn: 7591 init1: 7411 opt: 7432 Z-score: 2708.1 bits: 513.0 E(85289): 4.2e-144
Smith-Waterman score: 7551; 98.1% identity (98.1% similar) in 1151 aa overlap (1-1151:1-1129)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KB4 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
730 740 750 760 770 780
790 800 810 820 830 840
pF1KB4 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
790 800 810 820 830 840
850 860 870 880 890 900
pF1KB4 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KB4 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KB4 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KB4 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KB4 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
:::::::::::::::::::::::: ::::::::::::::
XP_016 FPNQQTPPSMMPGAVPGSGHPGVA----------------------DPGTPLPPDPTAPS
1090 1100 1110
1150
pF1KB4 PGTVTPVPPPQ
:::::::::::
XP_016 PGTVTPVPPPQ
1120
>>XP_011536995 (OMIM: 601734) PREDICTED: SWI/SNF complex (994 aa)
initn: 5789 init1: 3464 opt: 5707 Z-score: 2085.7 bits: 397.6 E(85289): 2e-109
Smith-Waterman score: 5707; 96.2% identity (97.3% similar) in 899 aa overlap (252-1149:1-894)
230 240 250 260 270 280
pF1KB4 EASVEDAPTPEKPRKVHAKWILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEV
::::::::::::::::::::::::::::::
XP_011 MNEEDYEVNDDKNPVSRRKKISAKTLTDEV
10 20 30
290 300 310 320 330 340
pF1KB4 NSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NSPDSDRRDKKGGNYKKRKRSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTK
40 50 60 70 80 90
350 360 370 380 390 400
pF1KB4 DMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMDEPSPVPNVEEVTLPKTVNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTG
100 110 120 130 140 150
410 420 430 440 450 460
pF1KB4 NKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKGEQTKNPDLHEDNVTEQTHHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEI
160 170 180 190 200 210
470 480 490 500 510 520
pF1KB4 YLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAYRNFMIDTYRLNPQEYLTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPT
220 230 240 250 260 270
530 540 550 560 570 580
pF1KB4 PMGPPPTSHFHVLADTPSGLVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMGPPPTSHFHVLADTPSGLVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPEL
280 290 300 310 320 330
590 600 610 620 630 640
pF1KB4 -TSASQQMLNFPDKGKEKPTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QTSASQQMLNFPDKGKEKPTDMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLL
340 350 360 370 380 390
650 660 670 680 690 700
pF1KB4 EALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EALEMYKDDWNKVSEHVGSRTQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSG
400 410 420 430 440 450
710 720 730 740 750 760
pF1KB4 NPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NPVMSTVAFLASVVDPRVASAAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKAD
460 470 480 490 500 510
770 780 790 800 810 820
pF1KB4 PAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAFGLESSGIAGTTSDEPERIEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKT
520 530 540 550 560 570
830 840 850 860 870 880
pF1KB4 SEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAPKKDEEKGKEGDSEKESEKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVE
580 590 600 610 620 630
890 900 910 920 930 940
pF1KB4 RDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RDIGEGNLSTAAAAALAAAAVKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELE
640 650 660 670 680 690
950 960 970 980 990 1000
pF1KB4 TIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TIMDREREALEYQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQ
700 710 720 730 740 750
1010 1020 1030 1040 1050 1060
pF1KB4 PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PIPPTGAAGPPAVHGLAVAPASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGA
760 770 780 790 800 810
1070 1080 1090 1100 1110 1120
pF1KB4 PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLP
::::::::::::::::::::::::::::::::::::::::::::...: .. : .:
XP_011 PQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAP--LGLPFG--MP
820 830 840 850 860
1130 1140 1150
pF1KB4 SASPLPDPGTPLPPDPTAPSPGTVTPVPPPQ
: : :. .: : : . :.::
XP_011 PPPPPPAPSI-IPFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHP
870 880 890 900 910 920
>>NP_003066 (OMIM: 601734) SWI/SNF complex subunit SMARC (1214 aa)
initn: 7305 init1: 3755 opt: 3970 Z-score: 1457.1 bits: 281.6 E(85289): 2e-74
Smith-Waterman score: 7176; 94.4% identity (95.3% similar) in 1149 aa overlap (1-1149:1-1114)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
:::::::::: :::::::::::::::::::
NP_003 LVPLQPKTPQQ------------------------------TSASQQMLNFPDKGKEKPT
550 560 570
610 620 630 640 650 660
pF1KB4 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB4 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB4 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB4 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB4 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB4 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB4 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB4 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KB4 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
::::::::::::::::::::::::...: .. : .: : : : . .: : :
NP_003 FPNQQTPPSMMPGAVPGSGHPGVAGNAP--LGLPFG--MPPPPPPPAP-SIIPFGSLADS
1060 1070 1080 1090 1100
1150
pF1KB4 PGTVTPVPPPQ
. :.::
NP_003 ISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGS
1110 1120 1130 1140 1150 1160
>>XP_005269160 (OMIM: 601734) PREDICTED: SWI/SNF complex (1213 aa)
initn: 7312 init1: 3762 opt: 3964 Z-score: 1454.9 bits: 281.2 E(85289): 2.7e-74
Smith-Waterman score: 7176; 94.4% identity (95.3% similar) in 1149 aa overlap (1-1149:1-1113)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
:::::::::: :::::::::::::::::::
XP_005 LVPLQPKTPQ-------------------------------TSASQQMLNFPDKGKEKPT
550 560
610 620 630 640 650 660
pF1KB4 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
570 580 590 600 610 620
670 680 690 700 710 720
pF1KB4 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
630 640 650 660 670 680
730 740 750 760 770 780
pF1KB4 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
690 700 710 720 730 740
790 800 810 820 830 840
pF1KB4 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
750 760 770 780 790 800
850 860 870 880 890 900
pF1KB4 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
810 820 830 840 850 860
910 920 930 940 950 960
pF1KB4 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KB4 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KB4 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KB4 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
::::::::::::::::::::::::...: .. : .: : : : . .: : :
XP_005 FPNQQTPPSMMPGAVPGSGHPGVAGNAP--LGLPFG--MPPPPPPPAP-SIIPFGSLADS
1050 1060 1070 1080 1090 1100
1150
pF1KB4 PGTVTPVPPPQ
. :.::
XP_005 ISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNLPATTTMPSSLPLGPGLGS
1110 1120 1130 1140 1150 1160
>>XP_016875375 (OMIM: 601734) PREDICTED: SWI/SNF complex (1099 aa)
initn: 4035 init1: 3755 opt: 3933 Z-score: 1444.3 bits: 279.1 E(85289): 1e-73
Smith-Waterman score: 7276; 95.4% identity (95.4% similar) in 1151 aa overlap (1-1151:1-1099)
10 20 30 40 50 60
pF1KB4 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAVRKKDGGPNVKYYEAADTVTQFDNVRLWLGKNYKKYIQAEPPTNKSLSSLVVQLLQFQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEVFGKHVSNAPLTKLPIKCFLDFKAGGSLCHILAAAYKFKSDQGWRRYDFQNPSRMDRN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEMFMTIEKSLVQNNCLSRPNIFLCPEIEPKLLGKLKDIIKRHQGTVTEDKNNASHVVYP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VPGNLEEEEWVRPVMKRDKQVLLHWGYYPDSYDTWIPASEIEASVEDAPTPEKPRKVHAK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WILDTDTFNEWMNEEDYEVNDDKNPVSRRKKISAKTLTDEVNSPDSDRRDKKGGNYKKRK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RSPSPSPTPEAKKKNAKKGPSTPYTKSKRGHREEEQEDLTKDMDEPSPVPNVEEVTLPKT
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNTKKDSESAPVKGGTMTDLDEQEDESMETTGKDEDENSTGNKGEQTKNPDLHEDNVTEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 THHIIIPSYAAWFDYNSVHAIERRALPEFFNGKNKSKTPEIYLAYRNFMIDTYRLNPQEY
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LTSTACRRNLAGDVCAIMRVHAFLEQWGLINYQVDAESRPTPMGPPPTSHFHVLADTPSG
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 LVPLQPKTPQGRQVDADTKAGRKGKELDDLVPETAKGKPELTSASQQMLNFPDKGKEKPT
:::::::::: :::::::::::::::::::
XP_016 LVPLQPKTPQQ------------------------------TSASQQMLNFPDKGKEKPT
550 560 570
610 620 630 640 650 660
pF1KB4 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMQNFGLRTDMYTKKNVPSKSKAAASATREWTEQETLLLLEALEMYKDDWNKVSEHVGSR
580 590 600 610 620 630
670 680 690 700 710 720
pF1KB4 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TQDECILHFLRLPIEDPYLEDSEASLGPLAYQPIPFSQSGNPVMSTVAFLASVVDPRVAS
640 650 660 670 680 690
730 740 750 760 770 780
pF1KB4 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAKSALEEFSKMKEEVPTALVEAHVRKVEEAAKVTGKADPAFGLESSGIAGTTSDEPER
700 710 720 730 740 750
790 800 810 820 830 840
pF1KB4 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IEESGNDEARVEGQATDEKKEPKEPREGGGAIEEEAKEKTSEAPKKDEEKGKEGDSEKES
760 770 780 790 800 810
850 860 870 880 890 900
pF1KB4 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKSDGDPIVDPEKEKEPKEGQEEVLKEVVESEGERKTKVERDIGEGNLSTAAAAALAAAA
820 830 840 850 860 870
910 920 930 940 950 960
pF1KB4 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VKAKHLAAVEERKIKSLVALLVETQMKKLEIKLRHFEELETIMDREREALEYQRQQLLAD
880 890 900 910 920 930
970 980 990 1000 1010 1020
pF1KB4 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RQAFHMEQLKYAEMRARQQHFQQMHQQQQQPPPALPPGSQPIPPTGAAGPPAVHGLAVAP
940 950 960 970 980 990
1030 1040 1050 1060 1070 1080
pF1KB4 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ASVVPAPAGSGAPPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSP
1000 1010 1020 1030 1040 1050
1090 1100 1110 1120 1130 1140
pF1KB4 FPNQQTPPSMMPGAVPGSGHPGVAAQSPAIVAAVQGNLLPSASPLPDPGTPLPPDPTAPS
:::::::::::::::::::::::: ::::::::::::::
XP_016 FPNQQTPPSMMPGAVPGSGHPGVA----------------------DPGTPLPPDPTAPS
1060 1070 1080
1150
pF1KB4 PGTVTPVPPPQ
:::::::::::
XP_016 PGTVTPVPPPQ
1090
1151 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:31:06 2016 done: Thu Nov 3 21:31:08 2016
Total Scan time: 12.680 Total Display time: 0.420
Function used was FASTA [36.3.4 Apr, 2011]