Result of FASTA (omim) for
pFN21AB4141
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4141, 749 aa
1>>>pF1KB4141 749 - 749 aa - 749 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3292+/-0.000424; mu= 1.7307+/- 0.026
mean_var=241.3525+/-49.043, 0's: 0 Z-trim(118.5): 46 B-trim: 0 in 0/57
Lambda= 0.082556
statistics sampled from 31395 (31441) to 31395 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.369), width: 16
Scan time: 12.810
The best scores are: opt bits E(85289)
XP_016877594 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_011519791 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877593 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877592 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877591 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_011519790 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877590 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_011519792 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877598 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877601 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_011519793 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_011519794 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877600 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877599 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877596 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877595 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
XP_016877597 (OMIM: 602712) PREDICTED: amyloid bet ( 749) 5038 613.9 7.8e-175
NP_005494 (OMIM: 602712) amyloid beta A4 precursor ( 749) 5038 613.9 7.8e-175
XP_011519796 (OMIM: 602712) PREDICTED: amyloid bet ( 702) 4590 560.5 8.6e-159
XP_016877604 (OMIM: 602712) PREDICTED: amyloid bet ( 737) 2827 350.5 1.4e-95
XP_016877602 (OMIM: 602712) PREDICTED: amyloid bet ( 737) 2827 350.5 1.4e-95
XP_016877605 (OMIM: 602712) PREDICTED: amyloid bet ( 737) 2827 350.5 1.4e-95
XP_016877603 (OMIM: 602712) PREDICTED: amyloid bet ( 737) 2827 350.5 1.4e-95
XP_016877606 (OMIM: 602712) PREDICTED: amyloid bet ( 737) 2827 350.5 1.4e-95
NP_001123886 (OMIM: 602712) amyloid beta A4 precur ( 737) 2827 350.5 1.4e-95
XP_011519795 (OMIM: 602712) PREDICTED: amyloid bet ( 739) 2825 350.3 1.7e-95
XP_011519797 (OMIM: 602712) PREDICTED: amyloid bet ( 453) 2801 347.3 8.5e-95
NP_001154 (OMIM: 602414) amyloid beta A4 precursor ( 837) 2278 285.2 7.7e-76
XP_011516919 (OMIM: 602414) PREDICTED: amyloid bet ( 837) 2278 285.2 7.7e-76
XP_016870159 (OMIM: 602414) PREDICTED: amyloid bet ( 837) 2278 285.2 7.7e-76
XP_011519798 (OMIM: 602712) PREDICTED: amyloid bet ( 441) 2163 271.3 6.2e-72
XP_005252025 (OMIM: 602414) PREDICTED: amyloid bet ( 826) 1930 243.7 2.3e-63
NP_004877 (OMIM: 604262) amyloid beta A4 precursor ( 575) 1131 148.4 7.7e-35
XP_006723014 (OMIM: 604262) PREDICTED: amyloid bet ( 408) 772 105.6 4.4e-22
XP_006723013 (OMIM: 604262) PREDICTED: amyloid bet ( 650) 772 105.7 6.3e-22
>>XP_016877594 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_011519791 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_011 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_016877593 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_016877592 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_016877591 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_011519790 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_011 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_016877590 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_011519792 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_011 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_016877598 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>XP_016877601 (OMIM: 602712) PREDICTED: amyloid beta A4 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3259.8 bits: 613.9 E(85289): 7.8e-175
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
XP_016 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
749 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:28:04 2016 done: Thu Nov 3 21:28:06 2016
Total Scan time: 12.810 Total Display time: 0.270
Function used was FASTA [36.3.4 Apr, 2011]