Result of FASTA (ccds) for
pFN21AB4141
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4141, 749 aa
1>>>pF1KB4141 749 - 749 aa - 749 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9596+/-0.00101; mu= 3.6264+/- 0.061
mean_var=199.6879+/-39.729, 0's: 0 Z-trim(110.8): 22 B-trim: 0 in 0/53
Lambda= 0.090761
statistics sampled from 11837 (11854) to 11837 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.706), E-opt: 0.2 (0.364), width: 16
Scan time: 4.310
The best scores are: opt bits E(32554)
CCDS10022.1 APBA2 gene_id:321|Hs108|chr15 ( 749) 5038 672.8 5.3e-193
CCDS45197.1 APBA2 gene_id:321|Hs108|chr15 ( 737) 2827 383.3 7.3e-106
CCDS6630.1 APBA1 gene_id:320|Hs108|chr9 ( 837) 2278 311.5 3.6e-84
CCDS12110.1 APBA3 gene_id:9546|Hs108|chr19 ( 575) 1131 161.2 4.3e-39
>>CCDS10022.1 APBA2 gene_id:321|Hs108|chr15 (749 aa)
initn: 5038 init1: 5038 opt: 5038 Z-score: 3578.5 bits: 672.8 E(32554): 5.3e-193
Smith-Waterman score: 5038; 99.9% identity (99.9% similar) in 749 aa overlap (1-749:1-749)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
430 440 450 460 470 480
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
550 560 570 580 590 600
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
610 620 630 640 650 660
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
670 680 690 700 710 720
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
CCDS10 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
730 740
>>CCDS45197.1 APBA2 gene_id:321|Hs108|chr15 (737 aa)
initn: 2827 init1: 2827 opt: 2827 Z-score: 2014.0 bits: 383.3 E(32554): 7.3e-106
Smith-Waterman score: 4933; 98.3% identity (98.3% similar) in 749 aa overlap (1-749:1-737)
10 20 30 40 50 60
pF1KB4 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MAHRKLESVGSGMLDHRVRPGPVPHSQEPESEDMELPLEGYVPEGLELAALRPESPAPEE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QECHNHSPDGDSSSDYVNNTSEEEDYDEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 YLAHSAHPVDTDECQEAVEEWTDSAGPHPHGHEAEGSQDYPDGQLPIPEDEPSVLEAHDQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 EEDGHYCASKEGYQDYYPEEANGNTGASPYRLRRGDGDLEDQEEDIDQIVAEIKMSLSMT
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 SITSASEASPEHGPEPGPEDSVEACPPIKASCSPSRHEARPKSLNLLPEAKHPGDPQRGF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 KPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
:::::::::: :::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KPKTRTPEERLKWPHEQVCNGLEQPRKQQRSDLNGPVDNNNIPETKKVASFPSFVAVPGP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSE
::::::::::::::::::::::::::::::::::::::::::::: :::
CCDS45 CEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVK------------NSE
370 380 390 400
430 440 450 460 470 480
pF1KB4 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 GDAQTLTEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSAS
410 420 430 440 450 460
490 500 510 520 530 540
pF1KB4 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 QDCIETTPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQ
470 480 490 500 510 520
550 560 570 580 590 600
pF1KB4 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 KEYSDIINTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANM
530 540 550 560 570 580
610 620 630 640 650 660
pF1KB4 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTV
590 600 610 620 630 640
670 680 690 700 710 720
pF1KB4 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 LIKRPDLKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQAL
650 660 670 680 690 700
730 740
pF1KB4 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
:::::::::::::::::::::::::::::
CCDS45 SNSVGEIHMKTMPAAMFRLLTGQETPLYI
710 720 730
>>CCDS6630.1 APBA1 gene_id:320|Hs108|chr9 (837 aa)
initn: 2033 init1: 1894 opt: 2278 Z-score: 1624.7 bits: 311.5 E(32554): 3.6e-84
Smith-Waterman score: 2395; 55.4% identity (70.9% similar) in 773 aa overlap (57-749:79-837)
30 40 50 60 70 80
pF1KB4 QEPESEDMELPLEGYVPEGLELAALRPESPAPEEQECHNHSPDGDSSSDYVNNTSEEEDY
: :. :::. ... : . . . :
CCDS66 GRHQRGRALEDLRAQLGQEEEERGECLARSASTESGFHNHTDTAEG--DVIAAARDGYDA
50 60 70 80 90 100
90 100 110 120 130
pF1KB4 DEGLPEEEEGITYYIRYCPEDDSYLEGMDCNGEEYLAHSA-------HPVDTDECQEAV-
... :.:. .: ..: :: . : : . . : . : : .. .: ..:.
CCDS66 ERAQDPEDES-AYAVQYRPEAEEYTEQAEAEHAEATHRRALPNHLHFHSLEHEEAMNAAY
110 120 130 140 150 160
140 150 160 170
pF1KB4 -------------------EEWTDSAGPHPHGHEAEGSQ---DYPDGQLPIPEDEPSVLE
: ..: .: . : .: :. : :: : . :.: .
CCDS66 SGYVYTHRLFHRGEDEPYSEPYADYGGLQEHVYEEIGDAPELDARDG-LRLYEQERDEAA
170 180 190 200 210 220
180 190 200 210 220 230
pF1KB4 AHDQEEDG----HYCASKEGYQDYYPEEANGNTGASPY-RLRRGDGDLEDQEEDIDQIVA
:. :: : :: ..: .: .::. .:: :. : .::::::::::
CCDS66 AYRQEALGARLHHYDERSDGESDSPEKEAE----FAPYPRM-----DSYEQEEDIDQIVA
230 240 250 260 270
240 250 260 270
pF1KB4 EIKMSLSMTSITSASEASPEHGPE----PGPEDSVEACPPIKASCSPSR-----------
:.:.:.: :. .:.: :: . : : . : ..: . .:
CCDS66 EVKQSMSSQSLDKAAEDMPEAEQDLERPPTPAGGRPDSPGLQAPAGQQRAVGPAGGGEAG
280 290 300 310 320 330
280 290 300 310 320
pF1KB4 ----HEARPK-SLNL--LPEAKHPGDPQRGFKPKTRTPEERPKWPHEQV------CNGL-
.: : :: . . :: . . .: : ..: : .: :.
CCDS66 QRYSKEKRDAISLAIKDIKEAIEEVKTRTIRSPYTPDEPKEPIWVMRQDISPTRDCDDQR
340 350 360 370 380 390
330 340 350 360
pF1KB4 ----EQPRKQQRSDLNG-----------PVDNNNIPETKK-VASFPSFVAVPGPCEPEDL
..: . : :.. ::. .. :..: .::::..: :::::.::::
CCDS66 PMDGDSPSPGSSSPLGAESSSTSLHPSDPVEASTNKESRKSLASFPTYVEVPGPCDPEDL
400 410 420 430 440 450
370 380 390 400 410 420
pF1KB4 IDGIIFAANYLGSTQLLSERNPSKNIRMMQAQEAVSRVKRMQKAAKIKKKANSEGDAQTL
::::::::::::::::::...::::.:::::::::::.: :: :: .::: ::..: .
CCDS66 IDGIIFAANYLGSTQLLSDKTPSKNVRMMQAQEAVSRIKMAQKLAKSRKKA-PEGESQPM
460 470 480 490 500 510
430 440 450 460 470 480
pF1KB4 TEVDLFISTQRIKVLNADTQETMMDHALRTISYIADIGNIVVLMARRRMPRSASQDCIET
:::::::::::::::::::::::::: ::::::::::::::::::::::::: ::. .:.
CCDS66 TEVDLFISTQRIKVLNADTQETMMDHPLRTISYIADIGNIVVLMARRRMPRSNSQENVEA
520 530 540 550 560 570
490 500 510 520 530 540
pF1KB4 TPGAQEGKKQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDI
. .:.::.::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS66 SHPSQDGKRQYKMICHVFESEDAQLIAQSIGQAFSVAYQEFLRANGINPEDLSQKEYSDL
580 590 600 610 620 630
550 560 570 580 590 600
pF1KB4 INTQEMYNDDLIHFSNSENCKELQLEKHKGEILGVVVVESGWGSILPTVILANMMNGGPA
.:::.::::::::::.:::::.. .::.::::::::.:::::::::::::.::::.::::
CCDS66 LNTQDMYNDDLIHFSKSENCKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPA
640 650 660 670 680 690
610 620 630 640 650 660
pF1KB4 ARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPD
.::::.::::::::::::::::::.:::.::::::::..:::::: :::::::::.:::
CCDS66 EKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVTTVLIRRPD
700 710 720 730 740 750
670 680 690 700 710 720
pF1KB4 LKYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATAHEKIVQALSNSVGE
:.::::::::::::::::::::::::::::::::::::::::::: :::::. :::.:::
CCDS66 LRYQLGFSVQNGIICSLMRGGIAERGGVRVGHRIIEINGQSVVATPHEKIVHILSNAVGE
760 770 780 790 800 810
730 740
pF1KB4 IHMKTMPAAMFRLLTGQETPLYI
::::::::::.::::.:: :.::
CCDS66 IHMKTMPAAMYRLLTAQEQPVYI
820 830
>>CCDS12110.1 APBA3 gene_id:9546|Hs108|chr19 (575 aa)
initn: 1602 init1: 934 opt: 1131 Z-score: 815.4 bits: 161.2 E(32554): 4.3e-39
Smith-Waterman score: 1633; 47.3% identity (68.2% similar) in 626 aa overlap (142-749:5-575)
120 130 140 150 160
pF1KB4 EGMDCNGEEYLAHSAHPVDTDECQEAVEEWTDSAGPH-PHGHEAEGSQDY--------PD
: : .: : . . :: .: ::
CCDS12 MDFPTISRSPSGPPAMDLEGPRDILVPSEDLTPD
10 20 30
170 180 190 200 210
pF1KB4 GQL-PIPEDEPSVLEAHDQEEDGHYCASKEGYQDY--YPEEANGNT--GAS-PYRLRRGD
.: :.: :. : . .:. . .: :.. : . : . :: : .. :
CCDS12 SQWDPMP-GGPGSLSRMELDES----SLQELVQQFEALPGDLVGPSPGGAPCPLHIATGH
40 50 60 70 80
220 230 240 250 260 270
pF1KB4 GDLEDQE-EDIDQIVAEIKMSLSMTSITSASEASPEHGPEPGPEDSVEACPPIKASCSPS
: : .:: : ... .. .. : : . :::. .: : . .:
CCDS12 G-LASQEIADAHGLLSAEAGRDDLLGLLHCEECPPS---QTGPEEPLEPAPRL---LQPP
90 100 110 120 130 140
280 290 300 310 320 330
pF1KB4 RHEARPKSLNLLPE-AKHPGDPQRGFKPKTRTPEERPKWPHEQVCNGLEQPRKQQRSDLN
. : . :: .. . :.: . .. .:: : : : : : :..
CCDS12 ED---PDEDSDSPEWVEGASAEQEGSRSSSSSPE--P-W-LETV--PLVTPEE-------
150 160 170 180
340 350 360 370 380 390
pF1KB4 GPVDNNNIPETKKVASFPSFVAVPGPCEPEDLIDGIIFAANYLGSTQLLSERNPSKNIRM
: . . ::: .::.:. :::::. :::.::.::.: :::::::.::::: . ::
CCDS12 -PPAGAQSPET--LASYPAPQEVPGPCDHEDLLDGVIFGARYLGSTQLVSERNPPTSTRM
190 200 210 220 230 240
400 410 420 430 440 450
pF1KB4 MQAQEAVSRVKRMQKAAKIKKKANSEGDAQTLTEVDLFISTQRIKVLNADTQETMMDHAL
::.::..::: .:..: .::::::.::.:::::.::.::.::::::
CCDS12 AQAREAMDRVK------------APDGETQPMTEVDLFVSTKRIKVLTADSQEAMMDHAL
250 260 270 280 290
460 470 480 490 500 510
pF1KB4 RTISYIADIGNIVVLMARRRMPRS-ASQDCIETTPGAQEGKKQYKMICHVFESEDAQLIA
.:::: :::: ..:::::::. : : :: .:.. :::.:::: .:::::::
CCDS12 HTISYTADIGCVLVLMARRRLARRPAPQD---------HGRRLYKMLCHVFYAEDAQLIA
300 310 320 330 340
520 530 540 550 560 570
pF1KB4 QSIGQAFSVAYQEFLRANGINPEDLSQKEYSDIINTQEMYNDDLIHFSNSENCKELQLEK
:.:::::..::..::: .::.: :: .. ...: :: :::::.::.:..:::
CCDS12 QAIGQAFAAAYSQFLRESGIDP---SQVGVHPSPGACHLHNGDLDHFSNSDNCREVHLEK
350 360 370 380 390
580 590 600 610 620 630
pF1KB4 HKGEILGVVVVESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLAT
..:: :::..:::::::.:::...::...:::: ::: :::::.. .::::::::::::.
CCDS12 RRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAA
400 410 420 430 440 450
640 650 660 670 680 690
pF1KB4 CQGIIKGLKNQTQVKLNIVSCPPVTTVLIKRPDLKYQLGFSVQNGIICSLMRGGIAERGG
::. .. :.::.: :.:: ::::::..:.:: . :::: :..::::::.:::::::::
CCDS12 CQAAVRETKSQTSVTLSIVHCPPVTTAIIHRPHAREQLGFCVEDGIICSLLRGGIAERGG
460 470 480 490 500 510
700 710 720 730 740
pF1KB4 VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETPLYI
.::::::::::::::::: : .:.. :... ::.:.:::::: .::::::: :.:.
CCDS12 IRVGHRIIEINGQSVVATPHARIIELLTEAYGEVHIKTMPAATYRLLTGQEQPVYL
520 530 540 550 560 570
749 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:28:04 2016 done: Thu Nov 3 21:28:04 2016
Total Scan time: 4.310 Total Display time: 0.100
Function used was FASTA [36.3.4 Apr, 2011]