Result of FASTA (omim) for
pFN21AB4051
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4051, 341 aa
1>>>pF1KB4051 341 - 341 aa - 341 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 15.0509+/-0.000659; mu= -32.6598+/- 0.039
mean_var=937.3871+/-217.234, 0's: 0 Z-trim(112.5): 64 B-trim: 0 in 0/54
Lambda= 0.041890
statistics sampled from 21470 (21478) to 21470 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.607), E-opt: 0.2 (0.252), width: 16
Scan time: 7.060
The best scores are: opt bits E(85289)
NP_001230462 (OMIM: 610785) serine/threonine-prote ( 341) 2242 151.8 2e-36
NP_001230461 (OMIM: 610785) serine/threonine-prote ( 341) 2242 151.8 2e-36
NP_690048 (OMIM: 610785) serine/threonine-protein ( 341) 2242 151.8 2e-36
XP_005245800 (OMIM: 610785) PREDICTED: serine/thre ( 341) 2242 151.8 2e-36
XP_011539094 (OMIM: 610785) PREDICTED: serine/thre ( 257) 1642 115.4 1.4e-25
XP_006710444 (OMIM: 610785) PREDICTED: serine/thre ( 263) 1622 114.2 3.2e-25
NP_543026 (OMIM: 609370) serine/threonine-protein ( 534) 1532 109.1 2.2e-23
XP_011527476 (OMIM: 609370) PREDICTED: serine/thre ( 430) 478 45.3 0.00028
>>NP_001230462 (OMIM: 610785) serine/threonine-protein k (341 aa)
initn: 2242 init1: 2242 opt: 2242 Z-score: 775.0 bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
250 260 270 280 290 300
310 320 330 340
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
:::::::::::::::::::::::::::::::::::::::::
NP_001 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
310 320 330 340
>>NP_001230461 (OMIM: 610785) serine/threonine-protein k (341 aa)
initn: 2242 init1: 2242 opt: 2242 Z-score: 775.0 bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
250 260 270 280 290 300
310 320 330 340
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
:::::::::::::::::::::::::::::::::::::::::
NP_001 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
310 320 330 340
>>NP_690048 (OMIM: 610785) serine/threonine-protein kina (341 aa)
initn: 2242 init1: 2242 opt: 2242 Z-score: 775.0 bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_690 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
250 260 270 280 290 300
310 320 330 340
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
:::::::::::::::::::::::::::::::::::::::::
NP_690 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
310 320 330 340
>>XP_005245800 (OMIM: 610785) PREDICTED: serine/threonin (341 aa)
initn: 2242 init1: 2242 opt: 2242 Z-score: 775.0 bits: 151.8 E(85289): 2e-36
Smith-Waterman score: 2242; 100.0% identity (100.0% similar) in 341 aa overlap (1-341:1-341)
10 20 30 40 50 60
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSARVAVKKIRCHAPENVELALREFWALSSI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 KSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSM
250 260 270 280 290 300
310 320 330 340
pF1KB4 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
:::::::::::::::::::::::::::::::::::::::::
XP_005 NGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
310 320 330 340
>>XP_011539094 (OMIM: 610785) PREDICTED: serine/threonin (257 aa)
initn: 1642 init1: 1642 opt: 1642 Z-score: 580.4 bits: 115.4 E(85289): 1.4e-25
Smith-Waterman score: 1642; 97.6% identity (99.2% similar) in 255 aa overlap (87-341:3-257)
60 70 80 90 100 110
pF1KB4 LSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLW
: ..:.: .:::::::::::::::::::::
XP_011 MRGRSGSVYPELVETSLKGEIAFDPRSAYYLW
10 20 30
120 130 140 150 160 170
pF1KB4 FVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTR
40 50 60 70 80 90
180 190 200 210 220 230
pF1KB4 LDTSDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDTSDLEPTLKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTA
100 110 120 130 140 150
240 250 260 270 280 290
pF1KB4 KADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KADIFALGIIIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVK
160 170 180 190 200 210
300 310 320 330 340
pF1KB4 KKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKSMNGRMKQLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
220 230 240 250
>>XP_006710444 (OMIM: 610785) PREDICTED: serine/threonin (263 aa)
initn: 1622 init1: 1622 opt: 1622 Z-score: 573.8 bits: 114.2 E(85289): 3.2e-25
Smith-Waterman score: 1622; 100.0% identity (100.0% similar) in 246 aa overlap (96-341:18-263)
70 80 90 100 110 120
pF1KB4 NVIHLEECILQKDGMVQKMSHGSNSSLYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGG
::::::::::::::::::::::::::::::
XP_006 MHRAFHPSEPRTPARSSLVETSLKGEIAFDPRSAYYLWFVMDFCDGG
10 20 30 40
130 140 150 160 170 180
pF1KB4 DMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DMNEYLLSRKPNRKTNTSFMLQLSSALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPT
50 60 70 80 90 100
190 200 210 220 230 240
pF1KB4 LKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LKVADFGLSKVCSASGQNPEEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGI
110 120 130 140 150 160
250 260 270 280 290 300
pF1KB4 IIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IIWAMLERITFIDTETKKELLGSYVKQGTEIVPVGEALLENPKMELLIPVKKKSMNGRMK
170 180 190 200 210 220
310 320 330 340
pF1KB4 QLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
::::::::::::::::::::::::::::::::::::
XP_006 QLIKEMLAANPQDRPDAFELELRLVQIAFKDSSWET
230 240 250 260
>>NP_543026 (OMIM: 609370) serine/threonine-protein kina (534 aa)
initn: 1491 init1: 527 opt: 1532 Z-score: 540.9 bits: 109.1 E(85289): 2.2e-23
Smith-Waterman score: 1532; 69.3% identity (87.0% similar) in 339 aa overlap (3-332:197-530)
10 20 30
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSA
:..:.:.:. :.:::::::::::: ...:
NP_543 AAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGA
170 180 190 200 210 220
40 50 60 70 80 90
pF1KB4 RVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSS-
::::::::: ::::::::: :::::.:.: .: ::...:::.::..:..:.::::..::
NP_543 RVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQ
230 240 250 260 270 280
100 110 120 130 140 150
pF1KB4 LYLQLVETSLKGE-IAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSS
:::.::::::::: : . ::::::.::.:::.:.:.:::.:. :: ::::::.:
NP_543 LYLRLVETSLKGERILGYAEEPCYLWFVMEFCEGGDLNQYVLSRRPDPATNKSFMLQLTS
290 300 310 320 330 340
160 170 180 190 200
pF1KB4 ALAFLHKNQIIHRDLKPDNILISQTRLDTSDLEPTLKVADFGLSKVCSA------SGQNP
:.::::::.:.:::::::::::.. : : : ::::::::::::.. :..
NP_543 AIAFLHKNHIVHRDLKPDNILITE-RSGT----PILKVADFGLSKVCAGLAPRGKEGNQD
350 360 370 380 390 400
210 220 230 240 250 260
pF1KB4 EEPVSVNKCFLSTACGTDFYMAPEVWEGHYTAKADIFALGIIIWAMLERITFIDTETKKE
.. :.::: .::.:::.:::::::::::::::::::::::::::::.:::::::.:::::
NP_543 NKNVNVNKYWLSSACGSDFYMAPEVWEGHYTAKADIFALGIIIWAMIERITFIDSETKKE
410 420 430 440 450 460
270 280 290 300 310 320
pF1KB4 LLGSYVKQGTEIVPVGEALLENPKMELLIPVKKK-SMNGRMKQLIKEMLAANPQDRPDAF
:::.:.::::::::::::::::::::: :: :.. ::. .:::.:.:::::::::::::
NP_543 LLGTYIKQGTEIVPVGEALLENPKMELHIPQKRRTSMSEGIKQLLKDMLAANPQDRPDAF
470 480 490 500 510 520
330 340
pF1KB4 ELELRLVQIAFKDSSWET
::: :. :.
NP_543 ELETRMDQVTCAA
530
>>XP_011527476 (OMIM: 609370) PREDICTED: serine/threonin (430 aa)
initn: 448 init1: 426 opt: 478 Z-score: 197.7 bits: 45.3 E(85289): 0.00028
Smith-Waterman score: 478; 68.6% identity (92.2% similar) in 102 aa overlap (3-103:293-394)
10 20 30
pF1KB4 MVSSQPKYDLIREVGRGSYGVVYEAVIRKTSA
:..:.:.:. :.:::::::::::: ...:
XP_011 AAAARAMDPVAAEAPGEAFLARRRPEGGGGSARPRYSLLAEIGRGSYGVVYEAVAGRSGA
270 280 290 300 310 320
40 50 60 70 80 90
pF1KB4 RVAVKKIRCHAPENVELALREFWALSSIKSQHPNVIHLEECILQKDGMVQKMSHGSNSS-
::::::::: ::::::::: :::::.:.: .: ::...:::.::..:..:.::::..::
XP_011 RVAVKKIRCDAPENVELALAEFWALTSLKRRHQNVVQFEECVLQRNGLAQRMSHGNKSSQ
330 340 350 360 370 380
100 110 120 130 140 150
pF1KB4 LYLQLVETSLKGEIAFDPRSAYYLWFVMDFCDGGDMNEYLLSRKPNRKTNTSFMLQLSSA
:::.::::::::
XP_011 LYLRLVETSLKGRFLGTHSLTTSPPEDGRGYRWWPGRLAISRQLDPAM
390 400 410 420 430
341 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:22:55 2016 done: Thu Nov 3 21:22:56 2016
Total Scan time: 7.060 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]