Result of FASTA (omim) for
pFN21AB4019
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB4019, 430 aa
1>>>pF1KB4019 430 - 430 aa - 430 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7396+/-0.000379; mu= 18.5417+/- 0.024
mean_var=142.1197+/-28.948, 0's: 0 Z-trim(118.1): 148 B-trim: 22 in 1/51
Lambda= 0.107584
statistics sampled from 30588 (30784) to 30588 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.704), E-opt: 0.2 (0.361), width: 16
Scan time: 9.900
The best scores are: opt bits E(85289)
XP_005245286 (OMIM: 176310) PREDICTED: pre-B-cell ( 430) 2813 448.1 2e-125
NP_002576 (OMIM: 176310) pre-B-cell leukemia trans ( 430) 2813 448.1 2e-125
XP_016856884 (OMIM: 176310) PREDICTED: pre-B-cell ( 406) 2608 416.3 7.3e-116
NP_001191892 (OMIM: 176310) pre-B-cell leukemia tr ( 420) 2608 416.3 7.4e-116
NP_006186 (OMIM: 176312) pre-B-cell leukemia trans ( 434) 2361 378.0 2.6e-104
XP_005245285 (OMIM: 176310) PREDICTED: pre-B-cell ( 486) 2212 354.9 2.6e-97
NP_001191890 (OMIM: 176310) pre-B-cell leukemia tr ( 347) 2182 350.1 5.3e-96
XP_016856885 (OMIM: 176310) PREDICTED: pre-B-cell ( 347) 2182 350.1 5.3e-96
NP_001128250 (OMIM: 176312) pre-B-cell leukemia tr ( 359) 2071 332.9 8.3e-91
XP_011507892 (OMIM: 176310) PREDICTED: pre-B-cell ( 462) 2007 323.1 9.5e-88
NP_002577 (OMIM: 176311) pre-B-cell leukemia trans ( 430) 1864 300.8 4.3e-81
NP_001317711 (OMIM: 176312) pre-B-cell leukemia tr ( 351) 1823 294.4 3.2e-79
XP_011507893 (OMIM: 176310) PREDICTED: pre-B-cell ( 403) 1581 256.9 7e-68
XP_011507894 (OMIM: 176310) PREDICTED: pre-B-cell ( 403) 1581 256.9 7e-68
NP_079521 (OMIM: 608127) pre-B-cell leukemia trans ( 374) 1580 256.7 7.4e-68
XP_006717193 (OMIM: 176312) PREDICTED: pre-B-cell ( 455) 1566 254.6 3.8e-67
XP_006717194 (OMIM: 176312) PREDICTED: pre-B-cell ( 372) 1549 251.9 2.1e-66
XP_016870275 (OMIM: 176312) PREDICTED: pre-B-cell ( 276) 1533 249.2 9.7e-66
XP_016882816 (OMIM: 608127) PREDICTED: pre-B-cell ( 343) 1292 211.9 2e-54
XP_016882815 (OMIM: 608127) PREDICTED: pre-B-cell ( 357) 1292 211.9 2.1e-54
XP_011526622 (OMIM: 608127) PREDICTED: pre-B-cell ( 391) 1292 212.0 2.2e-54
XP_011517057 (OMIM: 176312) PREDICTED: pre-B-cell ( 380) 1276 209.5 1.2e-53
XP_016882817 (OMIM: 608127) PREDICTED: pre-B-cell ( 327) 1224 201.3 2.9e-51
XP_011526624 (OMIM: 608127) PREDICTED: pre-B-cell ( 288) 1182 194.8 2.5e-49
XP_006722974 (OMIM: 608127) PREDICTED: pre-B-cell ( 288) 1182 194.8 2.5e-49
XP_016882818 (OMIM: 608127) PREDICTED: pre-B-cell ( 209) 810 136.8 4.9e-32
XP_006717196 (OMIM: 176312) PREDICTED: pre-B-cell ( 274) 643 111.1 3.7e-24
XP_016882819 (OMIM: 608127) PREDICTED: pre-B-cell ( 188) 301 57.8 2.8e-08
XP_016859632 (OMIM: 601739) PREDICTED: homeobox pr ( 352) 220 45.6 0.00025
XP_016859631 (OMIM: 601739) PREDICTED: homeobox pr ( 417) 220 45.6 0.00028
XP_016859630 (OMIM: 601739) PREDICTED: homeobox pr ( 433) 220 45.7 0.00028
NP_005404 (OMIM: 157170,269160,603714) homeobox pr ( 332) 203 42.9 0.0015
NP_758527 (OMIM: 601740) homeobox protein Meis2 is ( 306) 202 42.7 0.0016
XP_016877694 (OMIM: 601740) PREDICTED: homeobox pr ( 306) 202 42.7 0.0016
NP_002390 (OMIM: 601740) homeobox protein Meis2 is ( 381) 202 42.8 0.0018
XP_006720588 (OMIM: 601740) PREDICTED: homeobox pr ( 393) 202 42.8 0.0019
NP_733774 (OMIM: 601740) homeobox protein Meis2 is ( 394) 202 42.8 0.0019
NP_058628 (OMIM: 604994) homeobox protein SIX2 [Ho ( 291) 198 42.0 0.0024
XP_006720592 (OMIM: 601740) PREDICTED: homeobox pr ( 255) 196 41.7 0.0027
NP_001207411 (OMIM: 601740) homeobox protein Meis2 ( 470) 199 42.5 0.0029
NP_733776 (OMIM: 601740) homeobox protein Meis2 is ( 470) 199 42.5 0.0029
XP_016859635 (OMIM: 601739) PREDICTED: homeobox pr ( 246) 195 41.5 0.0029
XP_011519893 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 196 41.8 0.0032
XP_006720590 (OMIM: 601740) PREDICTED: homeobox pr ( 331) 196 41.8 0.0032
XP_016859633 (OMIM: 601739) PREDICTED: homeobox pr ( 321) 195 41.6 0.0035
XP_016859634 (OMIM: 601739) PREDICTED: homeobox pr ( 321) 195 41.6 0.0035
XP_005264382 (OMIM: 601739) PREDICTED: homeobox pr ( 325) 195 41.6 0.0035
NP_758526 (OMIM: 601740) homeobox protein Meis2 is ( 388) 196 41.9 0.0035
XP_006720589 (OMIM: 601740) PREDICTED: homeobox pr ( 389) 196 41.9 0.0035
XP_006720587 (OMIM: 601740) PREDICTED: homeobox pr ( 400) 196 41.9 0.0036
>>XP_005245286 (OMIM: 176310) PREDICTED: pre-B-cell leuk (430 aa)
initn: 2813 init1: 2813 opt: 2813 Z-score: 2372.8 bits: 448.1 E(85289): 2e-125
Smith-Waterman score: 2813; 100.0% identity (100.0% similar) in 430 aa overlap (1-430:1-430)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
370 380 390 400 410 420
430
pF1KB4 PGSVHSDTSN
::::::::::
XP_005 PGSVHSDTSN
430
>>NP_002576 (OMIM: 176310) pre-B-cell leukemia transcrip (430 aa)
initn: 2813 init1: 2813 opt: 2813 Z-score: 2372.8 bits: 448.1 E(85289): 2e-125
Smith-Waterman score: 2813; 100.0% identity (100.0% similar) in 430 aa overlap (1-430:1-430)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
370 380 390 400 410 420
430
pF1KB4 PGSVHSDTSN
::::::::::
NP_002 PGSVHSDTSN
430
>>XP_016856884 (OMIM: 176310) PREDICTED: pre-B-cell leuk (406 aa)
initn: 2608 init1: 2608 opt: 2608 Z-score: 2201.1 bits: 416.3 E(85289): 7.3e-116
Smith-Waterman score: 2608; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
::::::::::::::::::::::::::::::::::::::::
XP_016 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISEIARTY
370 380 390 400
430
pF1KB4 PGSVHSDTSN
>>NP_001191892 (OMIM: 176310) pre-B-cell leukemia transc (420 aa)
initn: 2608 init1: 2608 opt: 2608 Z-score: 2201.0 bits: 416.3 E(85289): 7.4e-116
Smith-Waterman score: 2608; 100.0% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB4 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
::::::::::::::::::::::::::::::::::::::::
NP_001 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISHLPRHPRQAHYHFRLPTWHP
370 380 390 400 410 420
430
pF1KB4 PGSVHSDTSN
>>NP_006186 (OMIM: 176312) pre-B-cell leukemia transcrip (434 aa)
initn: 1266 init1: 1200 opt: 2361 Z-score: 1993.6 bits: 378.0 E(85289): 2.6e-104
Smith-Waterman score: 2361; 83.2% identity (93.9% similar) in 440 aa overlap (1-430:1-434)
10 20 30 40 50
pF1KB4 MDEQPRLMHSHAGVGMAGHP---GLS----QHLQDGAGGTEGEGGRKQDIGDILQQIMTI
::.: :.... :::..::: :.. : ..:: : ::::::::::.:::::
NP_006 MDDQSRMLQTLAGVNLAGHSVQGGMALPPPPHGHEGADGD----GRKQDIGDILHQIMTI
10 20 30 40 50
60 70 80 90 100 110
pF1KB4 TDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLL
::::::::::.::::::::::::::.::::::::: :::::::::.: ::::::::::::
NP_006 TDQSLDEAQAKKHALNCHRMKPALFSVLCEIKEKTGLSIRGAQEEDPPDPQLMRLDNMLL
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB4 AEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACN
::::.::::::::::::::::::::. ::::.:::::::::.::::::::::::::::::
NP_006 AEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYHTELEKYEQACN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB4 EFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_006 EFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEAVMILRSRFLDA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB4 RRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKK
:::::::.::::::::::::::::::::::::::::::::.:::::::::::::::::::
NP_006 RRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSNWFGNKRIRYKK
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB4 NIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFNMSNSGDLFMSV
::::::::::.:::::::::... : ...:.:::.:::: :::.:::. ::::.::..
NP_006 NIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFNLPNSGDMFMNM
300 310 320 330 340 350
360 370 380 390 400 410
pF1KB4 QSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATT
::::::::::.:::::::::::::::::.:::::::::.....:::....::::::::::
NP_006 QSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNLNANGGWQDATT
360 370 380 390 400 410
420 430
pF1KB4 PSSVTSPTEGPGSVHSDTSN
::::::::::::::::::::
NP_006 PSSVTSPTEGPGSVHSDTSN
420 430
>>XP_005245285 (OMIM: 176310) PREDICTED: pre-B-cell leuk (486 aa)
initn: 2212 init1: 2212 opt: 2212 Z-score: 1868.1 bits: 354.9 E(85289): 2.6e-97
Smith-Waterman score: 2518; 87.9% identity (87.9% similar) in 462 aa overlap (25-430:25-486)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::
XP_005 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKT--------------------------------
::::::::::::::::::::::::::::
XP_005 AQARKHALNCHRMKPALFNVLCEIKEKTELKEARSRNCPSLFFLVTRIQSSVRHRVLSSA
70 80 90 100 110 120
90 100 110 120
pF1KB4 ------------------------VLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGG
::::::::::::::::::::::::::::::::::::
XP_005 STSGNPVTPQPTHHHPSFGWGEGKVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGG
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB4 GSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLR
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB4 EQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQA
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB4 TEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 TEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANI
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB4 YAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVG
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB4 ANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 ANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSV
430 440 450 460 470 480
430
pF1KB4 HSDTSN
::::::
XP_005 HSDTSN
>>NP_001191890 (OMIM: 176310) pre-B-cell leukemia transc (347 aa)
initn: 2292 init1: 2182 opt: 2182 Z-score: 1844.6 bits: 350.1 E(85289): 5.3e-96
Smith-Waterman score: 2182; 99.1% identity (99.4% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
:::::::::::::::::::::::::::::::::. :
NP_001 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGGYPSPCYQPDRRIQ
310 320 330 340
370 380 390 400 410 420
pF1KB4 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
>>XP_016856885 (OMIM: 176310) PREDICTED: pre-B-cell leuk (347 aa)
initn: 2292 init1: 2182 opt: 2182 Z-score: 1844.6 bits: 350.1 E(85289): 5.3e-96
Smith-Waterman score: 2182; 99.1% identity (99.4% similar) in 337 aa overlap (1-337:1-337)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB4 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB4 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB4 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB4 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQG
:::::::::::::::::::::::::::::::::. :
XP_016 EANIYAAKTAVTATNVSAHGSQANSPSTPNSAGGYPSPCYQPDRRIQ
310 320 330 340
370 380 390 400 410 420
pF1KB4 AQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEG
>>NP_001128250 (OMIM: 176312) pre-B-cell leukemia transc (359 aa)
initn: 1200 init1: 1200 opt: 2071 Z-score: 1751.3 bits: 332.9 E(85289): 8.3e-91
Smith-Waterman score: 2071; 88.1% identity (97.5% similar) in 361 aa overlap (73-430:1-359)
50 60 70 80 90 100
pF1KB4 IGDILQQIMTITDQSLDEAQARKHALNCHRMKPALFNVLCEIKEKTVLSIRGAQEEEPTD
::::::.::::::::: :::::::::.: :
NP_001 MKPALFSVLCEIKEKTGLSIRGAQEEDPPD
10 20 30
110 120 130 140 150 160
pF1KB4 PQLMRLDNMLLAEGVAGPEKGGGSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYH
:::::::::::::::.::::::::::::::::::::. ::::.:::::::::.:::::::
NP_001 PQLMRLDNMLLAEGVSGPEKGGGSAAAAAAAAASGGS-SDNSIEHSDYRAKLTQIRQIYH
40 50 60 70 80
170 180 190 200 210 220
pF1KB4 TELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEA
:::::::::::::::::::::::::::::::::::::::.::::::::::::::::::::
NP_001 TELEKYEQACNEFTTHVMNLLREQSRTRPISPKEIERMVGIIHRKFSSIQMQLKQSTCEA
90 100 110 120 130 140
230 240 250 260 270 280
pF1KB4 VMILRSRFLDARRKRRNFNKQATEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSN
::::::::::::::::::.::::::::::::::::::::::::::::::::.::::::::
NP_001 VMILRSRFLDARRKRRNFSKQATEILNEYFYSHLSNPYPSEEAKEELAKKCSITVSQVSN
150 160 170 180 190 200
290 300 310 320 330
pF1KB4 WFGNKRIRYKKNIGKFQEEANIYAAKTAVTATNVSA---HGSQANSPSTPNSAGSSSSFN
:::::::::::::::::::::.:::::::::... : ...:.:::.:::: :::.:::
NP_001 WFGNKRIRYKKNIGKFQEEANLYAAKTAVTAAHAVAAAVQNNQTNSPTTPNS-GSSGSFN
210 220 230 240 250 260
340 350 360 370 380 390
pF1KB4 MSNSGDLFMSVQSLNGDSYQGAQVGANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGI
. ::::.::..::::::::::.:::::::::::::::::.:::::::::.....:::...
NP_001 LPNSGDMFMNMQSLNGDSYQGSQVGANVQSQVDTLRHVINQTGGYSDGLGGNSLYSPHNL
270 280 290 300 310 320
400 410 420 430
pF1KB4 SANGGWQDATTPSSVTSPTEGPGSVHSDTSN
.::::::::::::::::::::::::::::::
NP_001 NANGGWQDATTPSSVTSPTEGPGSVHSDTSN
330 340 350
>>XP_011507892 (OMIM: 176310) PREDICTED: pre-B-cell leuk (462 aa)
initn: 2007 init1: 2007 opt: 2007 Z-score: 1696.4 bits: 323.1 E(85289): 9.5e-88
Smith-Waterman score: 2313; 87.0% identity (87.0% similar) in 432 aa overlap (25-400:25-456)
10 20 30 40 50 60
pF1KB4 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
::::::::::::::::::::::::::::::::::::
XP_011 MDEQPRLMHSHAGVGMAGHPGLSQHLQDGAGGTEGEGGRKQDIGDILQQIMTITDQSLDE
10 20 30 40 50 60
70 80
pF1KB4 AQARKHALNCHRMKPALFNVLCEIKEKT--------------------------------
::::::::::::::::::::::::::::
XP_011 AQARKHALNCHRMKPALFNVLCEIKEKTELKEARSRNCPSLFFLVTRIQSSVRHRVLSSA
70 80 90 100 110 120
90 100 110 120
pF1KB4 ------------------------VLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGG
::::::::::::::::::::::::::::::::::::
XP_011 STSGNPVTPQPTHHHPSFGWGEGKVLSIRGAQEEEPTDPQLMRLDNMLLAEGVAGPEKGG
130 140 150 160 170 180
130 140 150 160 170 180
pF1KB4 GSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSAAAAAAAAASGGAGSDNSVEHSDYRAKLSQIRQIYHTELEKYEQACNEFTTHVMNLLR
190 200 210 220 230 240
190 200 210 220 230 240
pF1KB4 EQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQSRTRPISPKEIERMVSIIHRKFSSIQMQLKQSTCEAVMILRSRFLDARRKRRNFNKQA
250 260 270 280 290 300
250 260 270 280 290 300
pF1KB4 TEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TEILNEYFYSHLSNPYPSEEAKEELAKKCGITVSQVSNWFGNKRIRYKKNIGKFQEEANI
310 320 330 340 350 360
310 320 330 340 350 360
pF1KB4 YAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YAAKTAVTATNVSAHGSQANSPSTPNSAGSSSSFNMSNSGDLFMSVQSLNGDSYQGAQVG
370 380 390 400 410 420
370 380 390 400 410 420
pF1KB4 ANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISANGGWQDATTPSSVTSPTEGPGSV
::::::::::::::::::::::::::::::::::::
XP_011 ANVQSQVDTLRHVISQTGGYSDGLAASQMYSPQGISEIARTY
430 440 450 460
430
pF1KB4 HSDTSN
430 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 21:21:37 2016 done: Thu Nov 3 21:21:38 2016
Total Scan time: 9.900 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]