Result of FASTA (omim) for
pFN21AA0288
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KA0288, 1084 aa
1>>>pF1KA0288 1084 - 1084 aa - 1084 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.6445+/-0.000461; mu= -7.8346+/- 0.028
mean_var=337.7576+/-71.901, 0's: 0 Z-trim(120.2): 146 B-trim: 1480 in 2/57
Lambda= 0.069787
statistics sampled from 35098 (35248) to 35098 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.413), width: 16
Scan time: 17.320
The best scores are: opt bits E(85289)
NP_006028 (OMIM: 605314) histone deacetylase 4 [Ho (1084) 7222 742.0 4.4e-213
XP_011510525 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_006712941 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_011510523 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_011510524 (OMIM: 605314) PREDICTED: histone dea (1089) 7202 740.0 1.8e-212
XP_011510527 (OMIM: 605314) PREDICTED: histone dea (1079) 7173 737.0 1.3e-211
XP_006712940 (OMIM: 605314) PREDICTED: histone dea (1108) 7173 737.1 1.4e-211
XP_011510526 (OMIM: 605314) PREDICTED: histone dea (1084) 7153 735.0 5.4e-211
XP_011510522 (OMIM: 605314) PREDICTED: histone dea (1090) 7153 735.0 5.4e-211
XP_011510519 (OMIM: 605314) PREDICTED: histone dea (1113) 7153 735.0 5.5e-211
XP_011510521 (OMIM: 605314) PREDICTED: histone dea (1103) 7123 732.0 4.4e-210
XP_011510520 (OMIM: 605314) PREDICTED: histone dea (1108) 7103 730.0 1.8e-209
XP_006712942 (OMIM: 605314) PREDICTED: histone dea (1062) 7015 721.1 8.1e-207
XP_006712943 (OMIM: 605314) PREDICTED: histone dea (1062) 7015 721.1 8.1e-207
XP_011510528 (OMIM: 605314) PREDICTED: histone dea (1065) 6988 718.4 5.3e-206
XP_011510529 (OMIM: 605314) PREDICTED: histone dea (1041) 6883 707.8 8e-203
XP_016860884 (OMIM: 605314) PREDICTED: histone dea ( 917) 6083 627.3 1.3e-178
XP_016860883 (OMIM: 605314) PREDICTED: histone dea (1069) 5381 556.6 2.7e-157
XP_011510532 (OMIM: 605314) PREDICTED: histone dea ( 673) 4469 464.7 8.1e-130
XP_011513931 (OMIM: 606543) PREDICTED: histone dea (1088) 3947 412.3 8e-114
XP_011513940 (OMIM: 606543) PREDICTED: histone dea (1069) 3906 408.1 1.4e-112
NP_848512 (OMIM: 606543) histone deacetylase 9 iso (1069) 3906 408.1 1.4e-112
XP_011513941 (OMIM: 606543) PREDICTED: histone dea (1069) 3906 408.1 1.4e-112
XP_016868315 (OMIM: 606543) PREDICTED: histone dea (1066) 3878 405.3 9.7e-112
NP_848510 (OMIM: 606543) histone deacetylase 9 iso (1066) 3878 405.3 9.7e-112
XP_011513946 (OMIM: 606543) PREDICTED: histone dea (1038) 3834 400.9 2e-110
XP_011513947 (OMIM: 606543) PREDICTED: histone dea (1038) 3834 400.9 2e-110
XP_011513948 (OMIM: 606543) PREDICTED: histone dea (1035) 3806 398.0 1.4e-109
NP_478056 (OMIM: 606543) histone deacetylase 9 iso (1011) 3744 391.8 1.1e-107
XP_011513939 (OMIM: 606543) PREDICTED: histone dea (1071) 3496 366.8 3.7e-100
XP_011513938 (OMIM: 606543) PREDICTED: histone dea (1071) 3496 366.8 3.7e-100
XP_016868316 (OMIM: 606543) PREDICTED: histone dea (1043) 3480 365.2 1.1e-99
XP_011513944 (OMIM: 606543) PREDICTED: histone dea (1043) 3480 365.2 1.1e-99
XP_011513943 (OMIM: 606543) PREDICTED: histone dea (1043) 3480 365.2 1.1e-99
XP_011513937 (OMIM: 606543) PREDICTED: histone dea (1074) 3480 365.2 1.1e-99
XP_011513950 (OMIM: 606543) PREDICTED: histone dea (1074) 3480 365.2 1.1e-99
XP_011513951 (OMIM: 606543) PREDICTED: histone dea (1074) 3480 365.2 1.1e-99
XP_011513933 (OMIM: 606543) PREDICTED: histone dea (1096) 3480 365.2 1.1e-99
XP_016879481 (OMIM: 605315) PREDICTED: histone dea (1156) 2978 314.7 2e-84
XP_016879484 (OMIM: 605315) PREDICTED: histone dea (1113) 2961 313.0 6.2e-84
XP_011522451 (OMIM: 605315) PREDICTED: histone dea (1114) 2961 313.0 6.2e-84
XP_016879482 (OMIM: 605315) PREDICTED: histone dea (1152) 2961 313.0 6.4e-84
XP_005256962 (OMIM: 605315) PREDICTED: histone dea (1122) 2952 312.1 1.2e-83
XP_016879480 (OMIM: 605315) PREDICTED: histone dea (1160) 2952 312.1 1.2e-83
XP_016879485 (OMIM: 605315) PREDICTED: histone dea (1081) 2946 311.5 1.7e-83
XP_011522452 (OMIM: 605315) PREDICTED: histone dea (1113) 2946 311.5 1.8e-83
NP_005465 (OMIM: 605315) histone deacetylase 5 iso (1122) 2946 311.5 1.8e-83
XP_005256963 (OMIM: 605315) PREDICTED: histone dea (1122) 2946 311.5 1.8e-83
NP_001015053 (OMIM: 605315) histone deacetylase 5 (1123) 2946 311.5 1.8e-83
XP_016879479 (OMIM: 605315) PREDICTED: histone dea (1160) 2946 311.5 1.8e-83
>>NP_006028 (OMIM: 605314) histone deacetylase 4 [Homo s (1084 aa)
initn: 7222 init1: 7222 opt: 7222 Z-score: 3946.5 bits: 742.0 E(85289): 4.4e-213
Smith-Waterman score: 7222; 100.0% identity (100.0% similar) in 1084 aa overlap (1-1084:1-1084)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KA0 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KA0 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
490 500 510 520 530 540
550 560 570 580 590 600
pF1KA0 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
550 560 570 580 590 600
610 620 630 640 650 660
pF1KA0 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
610 620 630 640 650 660
670 680 690 700 710 720
pF1KA0 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
670 680 690 700 710 720
730 740 750 760 770 780
pF1KA0 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
730 740 750 760 770 780
790 800 810 820 830 840
pF1KA0 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
790 800 810 820 830 840
850 860 870 880 890 900
pF1KA0 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
850 860 870 880 890 900
910 920 930 940 950 960
pF1KA0 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KA0 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KA0 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
1030 1040 1050 1060 1070 1080
pF1KA0 EPPL
::::
NP_006 EPPL
>>XP_011510525 (OMIM: 605314) PREDICTED: histone deacety (1089 aa)
initn: 4395 init1: 4395 opt: 7202 Z-score: 3935.6 bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
1030 1040 1050 1060 1070 1080
1080
pF1KA0 EPMEEEPPL
:::::::::
XP_011 EPMEEEPPL
>>XP_006712941 (OMIM: 605314) PREDICTED: histone deacety (1089 aa)
initn: 4395 init1: 4395 opt: 7202 Z-score: 3935.6 bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
1030 1040 1050 1060 1070 1080
1080
pF1KA0 EPMEEEPPL
:::::::::
XP_006 EPMEEEPPL
>>XP_011510523 (OMIM: 605314) PREDICTED: histone deacety (1089 aa)
initn: 4395 init1: 4395 opt: 7202 Z-score: 3935.6 bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
1030 1040 1050 1060 1070 1080
1080
pF1KA0 EPMEEEPPL
:::::::::
XP_011 EPMEEEPPL
>>XP_011510524 (OMIM: 605314) PREDICTED: histone deacety (1089 aa)
initn: 4395 init1: 4395 opt: 7202 Z-score: 3935.6 bits: 740.0 E(85289): 1.8e-212
Smith-Waterman score: 7202; 99.5% identity (99.5% similar) in 1089 aa overlap (1-1084:1-1089)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
370 380 390 400 410 420
430 440 450 460 470
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
1030 1040 1050 1060 1070 1080
1080
pF1KA0 EPMEEEPPL
:::::::::
XP_011 EPMEEEPPL
>>XP_011510527 (OMIM: 605314) PREDICTED: histone deacety (1079 aa)
initn: 7173 init1: 7173 opt: 7173 Z-score: 3919.9 bits: 737.0 E(85289): 1.3e-211
Smith-Waterman score: 7173; 100.0% identity (100.0% similar) in 1077 aa overlap (8-1084:3-1079)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KA0 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQALQHL
420 430 440 450 460 470
490 500 510 520 530 540
pF1KA0 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQALLDEPY
480 490 500 510 520 530
550 560 570 580 590 600
pF1KA0 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQ
540 550 560 570 580 590
610 620 630 640 650 660
pF1KA0 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTGLVYDT
600 610 620 630 640 650
670 680 690 700 710 720
pF1KA0 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVHSEAHT
660 670 680 690 700 710
730 740 750 760 770 780
pF1KA0 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAVGCVVE
720 730 740 750 760 770
790 800 810 820 830 840
pF1KA0 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKILIVDWD
780 790 800 810 820 830
850 860 870 880 890 900
pF1KA0 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFTGGLDP
840 850 860 870 880 890
910 920 930 940 950 960
pF1KA0 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGYLTKQL
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KA0 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVRSMEKV
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KA0 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDEEPMEE
1020 1030 1040 1050 1060 1070
pF1KA0 EPPL
::::
XP_011 EPPL
>>XP_006712940 (OMIM: 605314) PREDICTED: histone deacety (1108 aa)
initn: 7173 init1: 7173 opt: 7173 Z-score: 3919.7 bits: 737.1 E(85289): 1.4e-211
Smith-Waterman score: 7173; 100.0% identity (100.0% similar) in 1077 aa overlap (8-1084:32-1108)
10 20 30
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATA
::::::::::::::::::::::::::::::
XP_006 NIDLCAFEIQKTSSPGYEVWFRKQYLAVDGDGLSGRDQPVELLNPARVNHMPSTVDVATA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTGLGALPLHAQSLVGADRVSPSIHKLR
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 QHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQ
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 PESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVE
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 PGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 PGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASA
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 TFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 TFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGK
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 CECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVD
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 SDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNS
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 VAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAP
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 DEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVE
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 GHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 GHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNEL
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 DPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVT
1030 1040 1050 1060 1070 1080
1060 1070 1080
pF1KA0 AMASLSVGVKPAEKRPDEEPMEEEPPL
:::::::::::::::::::::::::::
XP_006 AMASLSVGVKPAEKRPDEEPMEEEPPL
1090 1100
>>XP_011510526 (OMIM: 605314) PREDICTED: histone deacety (1084 aa)
initn: 4395 init1: 4395 opt: 7153 Z-score: 3909.0 bits: 735.0 E(85289): 5.4e-211
Smith-Waterman score: 7153; 99.5% identity (99.5% similar) in 1082 aa overlap (8-1084:3-1084)
10 20 30 40 50 60
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MFDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSLP
10 20 30 40 50
70 80 90 100 110 120
pF1KA0 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEMLA
60 70 80 90 100 110
130 140 150 160 170 180
pF1KA0 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFVL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KA0 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDFP
180 190 200 210 220 230
250 260 270 280 290 300
pF1KA0 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSGP
240 250 260 270 280 290
310 320 330 340 350 360
pF1KA0 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLPA
300 310 320 330 340 350
370 380 390 400 410 420
pF1KA0 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVLL
360 370 380 390 400 410
430 440 450 460 470
pF1KA0 EQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNAQ
420 430 440 450 460 470
480 490 500 510 520 530
pF1KA0 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQAL
480 490 500 510 520 530
540 550 560 570 580 590
pF1KA0 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQAL
540 550 560 570 580 590
600 610 620 630 640 650
pF1KA0 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTTG
600 610 620 630 640 650
660 670 680 690 700 710
pF1KA0 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTVH
660 670 680 690 700 710
720 730 740 750 760 770
pF1KA0 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLAV
720 730 740 750 760 770
780 790 800 810 820 830
pF1KA0 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKIL
780 790 800 810 820 830
840 850 860 870 880 890
pF1KA0 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAFT
840 850 860 870 880 890
900 910 920 930 940 950
pF1KA0 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFGY
900 910 920 930 940 950
960 970 980 990 1000 1010
pF1KA0 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAVR
960 970 980 990 1000 1010
1020 1030 1040 1050 1060 1070
pF1KA0 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPDE
1020 1030 1040 1050 1060 1070
1080
pF1KA0 EPMEEEPPL
:::::::::
XP_011 EPMEEEPPL
1080
>>XP_011510522 (OMIM: 605314) PREDICTED: histone deacety (1090 aa)
initn: 4395 init1: 4395 opt: 7153 Z-score: 3909.0 bits: 735.0 E(85289): 5.4e-211
Smith-Waterman score: 7153; 99.5% identity (99.5% similar) in 1082 aa overlap (8-1084:9-1090)
10 20 30 40 50
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSL
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MRKLGPREDGLSGRDQPVELLNPARVNHMPSTVDVATALPLQVAPSAVPMDLRLDHQFSL
10 20 30 40 50 60
60 70 80 90 100 110
pF1KA0 PVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQHEQLSRQHEAQLHEHIKQQQEML
70 80 90 100 110 120
120 130 140 150 160 170
pF1KA0 AMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKNKEKGKESAVASTEVKMKLQEFV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KA0 LNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPPQSGVSTSYNHPVLGMYDAKDDF
190 200 210 220 230 240
240 250 260 270 280 290
pF1KA0 PLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVVTALKKRPLDVTDSACSSAPGSG
250 260 270 280 290 300
300 310 320 330 340 350
pF1KA0 PSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVAREGSAAPLPLYTSPSLPNITLGLP
310 320 330 340 350 360
360 370 380 390 400 410
pF1KA0 ATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYLSTSPLERDGGAAHSPLLQHMVL
370 380 390 400 410 420
420 430 440 450 460 470
pF1KA0 LEQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNA
:::::::::::: :::::::::::::::::::::::::::::::::::::::::::
XP_011 LEQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPSIHKLRQHRPLGRTQSAPLPQNA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KA0 QALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPSEPARQPESHPEETEEELREHQA
490 500 510 520 530 540
540 550 560 570 580 590
pF1KA0 LLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQA
550 560 570 580 590 600
600 610 620 630 640 650
pF1KA0 LLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPTKPRFTT
610 620 630 640 650 660
660 670 680 690 700 710
pF1KA0 GLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQETGLRGKCECIRGRKATLEELQTV
670 680 690 700 710 720
720 730 740 750 760 770
pF1KA0 HSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCGGVGVDSDTIWNEVHSAGAARLA
730 740 750 760 770 780
780 790 800 810 820 830
pF1KA0 VGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGFCYFNSVAVAAKLLQQRLSVSKI
790 800 810 820 830 840
840 850 860 870 880 890
pF1KA0 LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFPGSGAPDEVGTGPGVGFNVNMAF
850 860 870 880 890 900
900 910 920 930 940 950
pF1KA0 TGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSGFDAVEGHPTPLGGYNLSARCFG
910 920 930 940 950 960
960 970 980 990 1000 1010
pF1KA0 YLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSALLGNELDPLPEKVLQQRPNANAV
970 980 990 1000 1010 1020
1020 1030 1040 1050 1060 1070
pF1KA0 RSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEEAETVTAMASLSVGVKPAEKRPD
1030 1040 1050 1060 1070 1080
1080
pF1KA0 EEPMEEEPPL
::::::::::
XP_011 EEPMEEEPPL
1090
>>XP_011510519 (OMIM: 605314) PREDICTED: histone deacety (1113 aa)
initn: 4395 init1: 4395 opt: 7153 Z-score: 3908.8 bits: 735.0 E(85289): 5.5e-211
Smith-Waterman score: 7153; 99.5% identity (99.5% similar) in 1082 aa overlap (8-1084:32-1113)
10 20 30
pF1KA0 MSSQSHPDGLSGRDQPVELLNPARVNHMPSTVDVATA
::::::::::::::::::::::::::::::
XP_011 NIDLCAFEIQKTSSPGYEVWFRKQYLAVDGDGLSGRDQPVELLNPARVNHMPSTVDVATA
10 20 30 40 50 60
40 50 60 70 80 90
pF1KA0 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LPLQVAPSAVPMDLRLDHQFSLPVAEPALREQQLQQELLALKQKQQIQRQILIAEFQRQH
70 80 90 100 110 120
100 110 120 130 140 150
pF1KA0 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQLSRQHEAQLHEHIKQQQEMLAMKHQQELLEHQRKLERHRQEQELEKQHREQKLQQLKN
130 140 150 160 170 180
160 170 180 190 200 210
pF1KA0 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KEKGKESAVASTEVKMKLQEFVLNKKKALAHRNLNHCISSDPRYWYGKTQHSSLDQSSPP
190 200 210 220 230 240
220 230 240 250 260 270
pF1KA0 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QSGVSTSYNHPVLGMYDAKDDFPLRKTASEPNLKLRSRLKQKVAERRSSPLLRRKDGPVV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KA0 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TALKKRPLDVTDSACSSAPGSGPSSPNNSSGSVSAENGIAPAVPSIPAETSLAHRLVARE
310 320 330 340 350 360
340 350 360 370 380 390
pF1KA0 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSAAPLPLYTSPSLPNITLGLPATGPSAGTAGQQDAERLTLPALQQRLSLFPGTHLTPYL
370 380 390 400 410 420
400 410 420 430 440 450
pF1KA0 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVT-----GLGALPLHAQSLVGADRVSPS
:::::::::::::::::::::::::::::::::: :::::::::::::::::::::
XP_011 STSPLERDGGAAHSPLLQHMVLLEQPPAQAPLVTDWYLSGLGALPLHAQSLVGADRVSPS
430 440 450 460 470 480
460 470 480 490 500 510
pF1KA0 IHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IHKLRQHRPLGRTQSAPLPQNAQALQHLVIQQQHQQFLEKHKQQFQQQQLQMNKIIPKPS
490 500 510 520 530 540
520 530 540 550 560 570
pF1KA0 EPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EPARQPESHPEETEEELREHQALLDEPYLDRLPGQKEAHAQAGVQVKQEPIESDEEEAEP
550 560 570 580 590 600
580 590 600 610 620 630
pF1KA0 PREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQS
610 620 630 640 650 660
640 650 660 670 680 690
pF1KA0 SPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQET
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPASATFPVSVQEPPTKPRFTTGLVYDTLMLKHQCTCGSSSSHPEHAGRIQSIWSRLQET
670 680 690 700 710 720
700 710 720 730 740 750
pF1KA0 GLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLRGKCECIRGRKATLEELQTVHSEAHTLLYGTNPLNRQKLDSKKLLGSLASVFVRLPCG
730 740 750 760 770 780
760 770 780 790 800 810
pF1KA0 GVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GVGVDSDTIWNEVHSAGAARLAVGCVVELVFKVATGELKNGFAVVRPPGHHAEESTPMGF
790 800 810 820 830 840
820 830 840 850 860 870
pF1KA0 CYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CYFNSVAVAAKLLQQRLSVSKILIVDWDVHHGNGTQQAFYSDPSVLYMSLHRYDDGNFFP
850 860 870 880 890 900
880 890 900 910 920 930
pF1KA0 GSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GSGAPDEVGTGPGVGFNVNMAFTGGLDPPMGDAEYLAAFRTVVMPIASEFAPDVVLVSSG
910 920 930 940 950 960
940 950 960 970 980 990
pF1KA0 FDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FDAVEGHPTPLGGYNLSARCFGYLTKQLMGLAGGRIVLALEGGHDLTAICDASEACVSAL
970 980 990 1000 1010 1020
1000 1010 1020 1030 1040 1050
pF1KA0 LGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGNELDPLPEKVLQQRPNANAVRSMEKVMEIHSKYWRCLQRTTSTAGRSLIEAQTCENEE
1030 1040 1050 1060 1070 1080
1060 1070 1080
pF1KA0 AETVTAMASLSVGVKPAEKRPDEEPMEEEPPL
::::::::::::::::::::::::::::::::
XP_011 AETVTAMASLSVGVKPAEKRPDEEPMEEEPPL
1090 1100 1110
1084 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:38:08 2016 done: Thu Nov 3 19:38:10 2016
Total Scan time: 17.320 Total Display time: 0.500
Function used was FASTA [36.3.4 Apr, 2011]