Result of FASTA (omim) for
pFN21AF0188
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KF0188, 1277 aa
1>>>pF1KF0188 1277 - 1277 aa - 1277 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 11.1961+/-0.000474; mu= -5.0083+/- 0.029
mean_var=341.3325+/-69.066, 0's: 0 Z-trim(120.1): 237 B-trim: 140 in 2/52
Lambda= 0.069420
statistics sampled from 34577 (34885) to 34577 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.728), E-opt: 0.2 (0.409), width: 16
Scan time: 13.100
The best scores are: opt bits E(85289)
NP_001159743 (OMIM: 613324) spermatogenesis-associ (1277) 8684 885.0 0
NP_001273721 (OMIM: 613324) spermatogenesis-associ (1339) 8684 885.0 0
NP_694568 (OMIM: 613324) spermatogenesis-associate ( 652) 4446 460.3 1.9e-128
NP_001273724 (OMIM: 613324) spermatogenesis-associ ( 574) 3793 394.9 8.5e-109
NP_001273723 (OMIM: 613324) spermatogenesis-associ ( 596) 3793 394.9 8.8e-109
NP_001273722 (OMIM: 613324) spermatogenesis-associ ( 512) 2644 279.7 3.4e-74
NP_056135 (OMIM: 605216) rho guanine nucleotide ex ( 690) 2352 250.6 2.7e-65
XP_005263738 (OMIM: 605216) PREDICTED: rho guanine (1876) 2352 250.9 6e-65
XP_005263744 (OMIM: 605216) PREDICTED: rho guanine ( 567) 2320 247.3 2.2e-64
NP_127462 (OMIM: 605216) rho guanine nucleotide ex ( 670) 2225 237.9 1.8e-61
XP_011509576 (OMIM: 605216) PREDICTED: rho guanine (1870) 2200 235.7 2.3e-60
XP_011529192 (OMIM: 300429,300607) PREDICTED: rho ( 516) 2165 231.8 9.5e-60
XP_016884854 (OMIM: 300429,300607) PREDICTED: rho ( 516) 2165 231.8 9.5e-60
XP_016884853 (OMIM: 300429,300607) PREDICTED: rho ( 521) 2165 231.8 9.6e-60
XP_016884852 (OMIM: 300429,300607) PREDICTED: rho ( 521) 2165 231.8 9.6e-60
XP_016884855 (OMIM: 300429,300607) PREDICTED: rho ( 516) 2163 231.6 1.1e-59
NP_056000 (OMIM: 300429,300607) rho guanine nucleo ( 516) 2163 231.6 1.1e-59
XP_005262306 (OMIM: 300429,300607) PREDICTED: rho ( 523) 2163 231.6 1.1e-59
NP_001317424 (OMIM: 300429,300607) rho guanine nuc ( 495) 2084 223.7 2.5e-57
XP_005262307 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57
XP_005262308 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57
XP_016884856 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57
XP_016884857 (OMIM: 300429,300607) PREDICTED: rho ( 495) 2084 223.7 2.5e-57
XP_005263745 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57
XP_011509578 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57
XP_011509579 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57
XP_005263746 (OMIM: 605216) PREDICTED: rho guanine ( 483) 2071 222.3 6.2e-57
NP_001166950 (OMIM: 300429,300607) rho guanine nuc ( 463) 1847 199.9 3.4e-50
XP_011529194 (OMIM: 300429,300607) PREDICTED: rho ( 456) 1844 199.6 4.1e-50
XP_016884862 (OMIM: 300429,300607) PREDICTED: rho ( 414) 1808 196.0 4.6e-49
NP_001166951 (OMIM: 300429,300607) rho guanine nuc ( 414) 1808 196.0 4.6e-49
XP_016884864 (OMIM: 300429,300607) PREDICTED: rho ( 385) 1611 176.2 3.8e-43
XP_016884865 (OMIM: 300429,300607) PREDICTED: rho ( 375) 1607 175.8 4.9e-43
XP_016884866 (OMIM: 300429,300607) PREDICTED: rho ( 365) 1599 175.0 8.4e-43
XP_016884867 (OMIM: 300429,300607) PREDICTED: rho ( 362) 1595 174.6 1.1e-42
XP_016884868 (OMIM: 300429,300607) PREDICTED: rho ( 344) 1520 167.1 1.9e-40
XP_016884859 (OMIM: 300429,300607) PREDICTED: rho ( 472) 1407 155.8 6.3e-37
XP_016884858 (OMIM: 300429,300607) PREDICTED: rho ( 479) 1407 155.8 6.4e-37
XP_016884860 (OMIM: 300429,300607) PREDICTED: rho ( 451) 1328 147.9 1.5e-34
XP_016884861 (OMIM: 300429,300607) PREDICTED: rho ( 451) 1328 147.9 1.5e-34
XP_016884869 (OMIM: 300429,300607) PREDICTED: rho ( 305) 1280 143.0 3e-33
XP_016884863 (OMIM: 300429,300607) PREDICTED: rho ( 412) 1088 123.8 2.4e-27
NP_079446 (OMIM: 612139) phosphatidylinositol 3,4, ( 979) 651 80.4 6.9e-14
XP_011515914 (OMIM: 612139) PREDICTED: phosphatidy (1157) 651 80.4 7.9e-14
NP_079146 (OMIM: 612139) phosphatidylinositol 3,4, (1606) 651 80.5 1e-13
NP_065871 (OMIM: 606905) phosphatidylinositol 3,4, (1659) 602 75.6 3.1e-12
XP_016859720 (OMIM: 605216) PREDICTED: rho guanine (1441) 541 69.5 1.9e-10
XP_006723397 (OMIM: 611893,616763) PREDICTED: plec (1327) 397 55.0 4e-06
XP_016882640 (OMIM: 611893,616763) PREDICTED: plec (1371) 397 55.0 4.1e-06
XP_016882639 (OMIM: 611893,616763) PREDICTED: plec (1374) 397 55.0 4.1e-06
>>NP_001159743 (OMIM: 613324) spermatogenesis-associated (1277 aa)
initn: 8684 init1: 8684 opt: 8684 Z-score: 4716.7 bits: 885.0 E(85289): 0
Smith-Waterman score: 8684; 100.0% identity (100.0% similar) in 1277 aa overlap (1-1277:1-1277)
10 20 30 40 50 60
pF1KF0 MTQAAVRPWAPCLENMTTAPNGLGPGPAAPCAGSDLKDAKMVTSLACGNGVCGCSPGGDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTQAAVRPWAPCLENMTTAPNGLGPGPAAPCAGSDLKDAKMVTSLACGNGVCGCSPGGDT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KF0 DTQEAKLSPAKLVRLFSTSRKRTGAHPERPHSMVLVGNSSTWNTLASFRKMGSFKKLKSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DTQEAKLSPAKLVRLFSTSRKRTGAHPERPHSMVLVGNSSTWNTLASFRKMGSFKKLKSS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KF0 VLKGIQSREGSNACSKGEASEHGLGKSIPNGAVPGAQASRGSPLAPGPACGALRPAEWGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLKGIQSREGSNACSKGEASEHGLGKSIPNGAVPGAQASRGSPLAPGPACGALRPAEWGT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KF0 LDGSDLEDTDDAFQRSTHRSRSLRRAYGLGRICLLDAPQNHATPTIATGQVPAVCEILVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LDGSDLEDTDDAFQRSTHRSRSLRRAYGLGRICLLDAPQNHATPTIATGQVPAVCEILVR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KF0 DPENNSMGYRRSKSTDNLAFLKKSSFKRKSTSNLADLRTAHDARVPQRTLSSSSTDSQKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DPENNSMGYRRSKSTDNLAFLKKSSFKRKSTSNLADLRTAHDARVPQRTLSSSSTDSQKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KF0 GSGRTKRWRSPIRAKDFDRVFKLVSNVTEAAWRRESPRSGAPSPGEASLRLQAHSRLHDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GSGRTKRWRSPIRAKDFDRVFKLVSNVTEAAWRRESPRSGAPSPGEASLRLQAHSRLHDD
310 320 330 340 350 360
370 380 390 400 410 420
pF1KF0 YSRRVSRSTEQDSRRGGAVMHGTTATCTVAPGFGSATSKGPHLDADTAVFPLETKSSWAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSRRVSRSTEQDSRRGGAVMHGTTATCTVAPGFGSATSKGPHLDADTAVFPLETKSSWAV
370 380 390 400 410 420
430 440 450 460 470 480
pF1KF0 ESDSSCTCSSLPSPIVQDVLSKDSCDPNAGSQLTFDPEQPPTPLRPTTPKPQSPQSPQSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESDSSCTCSSLPSPIVQDVLSKDSCDPNAGSQLTFDPEQPPTPLRPTTPKPQSPQSPQSP
430 440 450 460 470 480
490 500 510 520 530 540
pF1KF0 GAGSASCHSNHSALSANSEESEGRAEEPAQREPGPVSLQDPLEATHGDEGSKDLLVNIGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAGSASCHSNHSALSANSEESEGRAEEPAQREPGPVSLQDPLEATHGDEGSKDLLVNIGV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KF0 AAGPEEKEKEEVVPDGPWRRSSSQDEERTEAQRTPKRRWGSGRRPRPRPFSDYGQLASRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AAGPEEKEKEEVVPDGPWRRSSSQDEERTEAQRTPKRRWGSGRRPRPRPFSDYGQLASRS
550 560 570 580 590 600
610 620 630 640 650 660
pF1KF0 LSIPEDSVAADPQKEDRVDEDPQASMTSASPEDQNAPVGCPKGARRRRPISVIGGVSLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSIPEDSVAADPQKEDRVDEDPQASMTSASPEDQNAPVGCPKGARRRRPISVIGGVSLYG
610 620 630 640 650 660
670 680 690 700 710 720
pF1KF0 TNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRAS
670 680 690 700 710 720
730 740 750 760 770 780
pF1KF0 NVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVVCAEAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVVCAEAL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KF0 WDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSS
790 800 810 820 830 840
850 860 870 880 890 900
pF1KF0 STPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTG
850 860 870 880 890 900
910 920 930 940 950 960
pF1KF0 MFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYC
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KF0 NNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLK
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KF0 YTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSE
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KF0 LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDG
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KF0 RDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISE
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KF0 NQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKR
1210 1220 1230 1240 1250 1260
1270
pF1KF0 KSSLFWHTFNRLTPFRK
:::::::::::::::::
NP_001 KSSLFWHTFNRLTPFRK
1270
>>NP_001273721 (OMIM: 613324) spermatogenesis-associated (1339 aa)
initn: 8684 init1: 8684 opt: 8684 Z-score: 4716.4 bits: 885.0 E(85289): 0
Smith-Waterman score: 8684; 100.0% identity (100.0% similar) in 1277 aa overlap (1-1277:63-1339)
10 20 30
pF1KF0 MTQAAVRPWAPCLENMTTAPNGLGPGPAAP
::::::::::::::::::::::::::::::
NP_001 DVQGRCECQDGIPGDEGLELRSADSAVPVAMTQAAVRPWAPCLENMTTAPNGLGPGPAAP
40 50 60 70 80 90
40 50 60 70 80 90
pF1KF0 CAGSDLKDAKMVTSLACGNGVCGCSPGGDTDTQEAKLSPAKLVRLFSTSRKRTGAHPERP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CAGSDLKDAKMVTSLACGNGVCGCSPGGDTDTQEAKLSPAKLVRLFSTSRKRTGAHPERP
100 110 120 130 140 150
100 110 120 130 140 150
pF1KF0 HSMVLVGNSSTWNTLASFRKMGSFKKLKSSVLKGIQSREGSNACSKGEASEHGLGKSIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSMVLVGNSSTWNTLASFRKMGSFKKLKSSVLKGIQSREGSNACSKGEASEHGLGKSIPN
160 170 180 190 200 210
160 170 180 190 200 210
pF1KF0 GAVPGAQASRGSPLAPGPACGALRPAEWGTLDGSDLEDTDDAFQRSTHRSRSLRRAYGLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAVPGAQASRGSPLAPGPACGALRPAEWGTLDGSDLEDTDDAFQRSTHRSRSLRRAYGLG
220 230 240 250 260 270
220 230 240 250 260 270
pF1KF0 RICLLDAPQNHATPTIATGQVPAVCEILVRDPENNSMGYRRSKSTDNLAFLKKSSFKRKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RICLLDAPQNHATPTIATGQVPAVCEILVRDPENNSMGYRRSKSTDNLAFLKKSSFKRKS
280 290 300 310 320 330
280 290 300 310 320 330
pF1KF0 TSNLADLRTAHDARVPQRTLSSSSTDSQKLGSGRTKRWRSPIRAKDFDRVFKLVSNVTEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TSNLADLRTAHDARVPQRTLSSSSTDSQKLGSGRTKRWRSPIRAKDFDRVFKLVSNVTEA
340 350 360 370 380 390
340 350 360 370 380 390
pF1KF0 AWRRESPRSGAPSPGEASLRLQAHSRLHDDYSRRVSRSTEQDSRRGGAVMHGTTATCTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AWRRESPRSGAPSPGEASLRLQAHSRLHDDYSRRVSRSTEQDSRRGGAVMHGTTATCTVA
400 410 420 430 440 450
400 410 420 430 440 450
pF1KF0 PGFGSATSKGPHLDADTAVFPLETKSSWAVESDSSCTCSSLPSPIVQDVLSKDSCDPNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PGFGSATSKGPHLDADTAVFPLETKSSWAVESDSSCTCSSLPSPIVQDVLSKDSCDPNAG
460 470 480 490 500 510
460 470 480 490 500 510
pF1KF0 SQLTFDPEQPPTPLRPTTPKPQSPQSPQSPGAGSASCHSNHSALSANSEESEGRAEEPAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SQLTFDPEQPPTPLRPTTPKPQSPQSPQSPGAGSASCHSNHSALSANSEESEGRAEEPAQ
520 530 540 550 560 570
520 530 540 550 560 570
pF1KF0 REPGPVSLQDPLEATHGDEGSKDLLVNIGVAAGPEEKEKEEVVPDGPWRRSSSQDEERTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REPGPVSLQDPLEATHGDEGSKDLLVNIGVAAGPEEKEKEEVVPDGPWRRSSSQDEERTE
580 590 600 610 620 630
580 590 600 610 620 630
pF1KF0 AQRTPKRRWGSGRRPRPRPFSDYGQLASRSLSIPEDSVAADPQKEDRVDEDPQASMTSAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AQRTPKRRWGSGRRPRPRPFSDYGQLASRSLSIPEDSVAADPQKEDRVDEDPQASMTSAS
640 650 660 670 680 690
640 650 660 670 680 690
pF1KF0 PEDQNAPVGCPKGARRRRPISVIGGVSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PEDQNAPVGCPKGARRRRPISVIGGVSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKA
700 710 720 730 740 750
700 710 720 730 740 750
pF1KF0 VSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQ
760 770 780 790 800 810
760 770 780 790 800 810
pF1KF0 ASPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ASPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWW
820 830 840 850 860 870
820 830 840 850 860 870
pF1KF0 WGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVI
880 890 900 910 920 930
880 890 900 910 920 930
pF1KF0 REIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 REIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEK
940 950 960 970 980 990
940 950 960 970 980 990
pF1KF0 QYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQ
1000 1010 1020 1030 1040 1050
1000 1010 1020 1030 1040 1050
pF1KF0 QMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERK
1060 1070 1080 1090 1100 1110
1060 1070 1080 1090 1100 1110
pF1KF0 RKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVS
1120 1130 1140 1150 1160 1170
1120 1130 1140 1150 1160 1170
pF1KF0 CKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKK
1180 1190 1200 1210 1220 1230
1180 1190 1200 1210 1220 1230
pF1KF0 QEDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QEDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPH
1240 1250 1260 1270 1280 1290
1240 1250 1260 1270
pF1KF0 QGLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
1300 1310 1320 1330
>>NP_694568 (OMIM: 613324) spermatogenesis-associated pr (652 aa)
initn: 4446 init1: 4446 opt: 4446 Z-score: 2426.9 bits: 460.3 E(85289): 1.9e-128
Smith-Waterman score: 4446; 100.0% identity (100.0% similar) in 652 aa overlap (626-1277:1-652)
600 610 620 630 640 650
pF1KF0 LASRSLSIPEDSVAADPQKEDRVDEDPQASMTSASPEDQNAPVGCPKGARRRRPISVIGG
::::::::::::::::::::::::::::::
NP_694 MTSASPEDQNAPVGCPKGARRRRPISVIGG
10 20 30
660 670 680 690 700 710
pF1KF0 VSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 VSLYGTNQTEELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRR
40 50 60 70 80 90
720 730 740 750 760 770
pF1KF0 QMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 QMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGGEQLAINELISDGNVV
100 110 120 130 140 150
780 790 800 810 820 830
pF1KF0 CAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 CAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEEL
160 170 180 190 200 210
840 850 860 870 880 890
pF1KF0 SENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 SENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQC
220 230 240 250 260 270
900 910 920 930 940 950
pF1KF0 RKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 RKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAI
280 290 300 310 320 330
960 970 980 990 1000 1010
pF1KF0 YSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 YSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQL
340 350 360 370 380 390
1020 1030 1040 1050 1060 1070
pF1KF0 AELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 AELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDIL
400 410 420 430 440 450
1080 1090 1100 1110 1120 1130
pF1KF0 DRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 DRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELV
460 470 480 490 500 510
1140 1150 1160 1170 1180 1190
pF1KF0 DLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 DLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMG
520 530 540 550 560 570
1200 1210 1220 1230 1240 1250
pF1KF0 MEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_694 MEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQGLHPIHQRHITMPTSVPQQQVFGL
580 590 600 610 620 630
1260 1270
pF1KF0 AEPKRKSSLFWHTFNRLTPFRK
::::::::::::::::::::::
NP_694 AEPKRKSSLFWHTFNRLTPFRK
640 650
>>NP_001273724 (OMIM: 613324) spermatogenesis-associated (574 aa)
initn: 3793 init1: 3793 opt: 3793 Z-score: 2074.2 bits: 394.9 E(85289): 8.5e-109
Smith-Waterman score: 3793; 100.0% identity (100.0% similar) in 556 aa overlap (722-1277:19-574)
700 710 720 730 740 750
pF1KF0 SARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQA
::::::::::::::::::::::::::::::
NP_001 MVARGEIARFWSLESLHLVSSDGGTEPSALVDDNGSEEDFSYEDLCQA
10 20 30 40
760 770 780 790 800 810
pF1KF0 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW
50 60 70 80 90 100
820 830 840 850 860 870
pF1KF0 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR
110 120 130 140 150 160
880 890 900 910 920 930
pF1KF0 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ
170 180 190 200 210 220
940 950 960 970 980 990
pF1KF0 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ
230 240 250 260 270 280
1000 1010 1020 1030 1040 1050
pF1KF0 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR
290 300 310 320 330 340
1060 1070 1080 1090 1100 1110
pF1KF0 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC
350 360 370 380 390 400
1120 1130 1140 1150 1160 1170
pF1KF0 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ
410 420 430 440 450 460
1180 1190 1200 1210 1220 1230
pF1KF0 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ
470 480 490 500 510 520
1240 1250 1260 1270
pF1KF0 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
530 540 550 560 570
>>NP_001273723 (OMIM: 613324) spermatogenesis-associated (596 aa)
initn: 3793 init1: 3793 opt: 3793 Z-score: 2074.0 bits: 394.9 E(85289): 8.8e-109
Smith-Waterman score: 3793; 100.0% identity (100.0% similar) in 556 aa overlap (722-1277:41-596)
700 710 720 730 740 750
pF1KF0 SARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQA
::::::::::::::::::::::::::::::
NP_001 KKQRKKLDQGLILKKEKYRKEKKCASLSFEVSSDGGTEPSALVDDNGSEEDFSYEDLCQA
20 30 40 50 60 70
760 770 780 790 800 810
pF1KF0 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW
80 90 100 110 120 130
820 830 840 850 860 870
pF1KF0 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR
140 150 160 170 180 190
880 890 900 910 920 930
pF1KF0 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ
200 210 220 230 240 250
940 950 960 970 980 990
pF1KF0 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ
260 270 280 290 300 310
1000 1010 1020 1030 1040 1050
pF1KF0 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR
320 330 340 350 360 370
1060 1070 1080 1090 1100 1110
pF1KF0 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC
380 390 400 410 420 430
1120 1130 1140 1150 1160 1170
pF1KF0 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ
440 450 460 470 480 490
1180 1190 1200 1210 1220 1230
pF1KF0 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ
500 510 520 530 540 550
1240 1250 1260 1270
pF1KF0 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
560 570 580 590
>>NP_001273722 (OMIM: 613324) spermatogenesis-associated (512 aa)
initn: 2644 init1: 2644 opt: 2644 Z-score: 1453.0 bits: 279.7 E(85289): 3.4e-74
Smith-Waterman score: 3252; 88.8% identity (88.8% similar) in 556 aa overlap (722-1277:19-512)
700 710 720 730 740 750
pF1KF0 SARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQA
::::::::::::::::::::::::::::::
NP_001 MVARGEIARFWSLESLHLVSSDGGTEPSALVDDNGSEEDFSYEDLCQA
10 20 30 40
760 770 780 790 800 810
pF1KF0 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SPRYLQPGGEQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWW
50 60 70 80 90 100
820 830 840 850 860 870
pF1KF0 GRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIR
::::::::::::::::
NP_001 GRSEDKEAWFPASFVR--------------------------------------------
110 120
880 890 900 910 920 930
pF1KF0 EIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ
::::::::::::::::::::::::::::::::::::::::::
NP_001 ------------------GYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQ
130 140 150 160
940 950 960 970 980 990
pF1KF0 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQ
170 180 190 200 210 220
1000 1010 1020 1030 1040 1050
pF1KF0 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKR
230 240 250 260 270 280
1060 1070 1080 1090 1100 1110
pF1KF0 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITKQGKSQQRTFFLFDHQLVSC
290 300 310 320 330 340
1120 1130 1140 1150 1160 1170
pF1KF0 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQ
350 360 370 380 390 400
1180 1190 1200 1210 1220 1230
pF1KF0 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAGHGKSKGYNRCPVAPPHQ
410 420 430 440 450 460
1240 1250 1260 1270
pF1KF0 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
470 480 490 500 510
>>NP_056135 (OMIM: 605216) rho guanine nucleotide exchan (690 aa)
initn: 2275 init1: 1140 opt: 2352 Z-score: 1293.1 bits: 250.6 E(85289): 2.7e-65
Smith-Waterman score: 2352; 60.3% identity (81.9% similar) in 587 aa overlap (696-1277:118-690)
670 680 690 700 710 720
pF1KF0 ELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSD
: .:::.: ::...: .. .. . :
NP_056 RLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAMP-D
90 100 110 120 130 140
730 740 750 760 770 780
pF1KF0 GGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGG--EQLAINELISDGNVVCAEALWDH
:. . .. .:. :::::. :.:: ..: .: .::: ::::::::::::.::::::::::
NP_056 GALDTAVCADEVGSEEDL-YDDLHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDH
150 160 170 180 190 200
790 800 810 820 830 840
pF1KF0 VTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTP
::::::::::::::::.:..:.:..::::: : :.:::::::::::::.: .....
NP_056 VTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLA
210 220 230 240 250 260
850 860 870 880 890 900
pF1KF0 SEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFT
.. :... . .:.::::::: ::..::: ::::::::::::.:::::.. ::.
NP_056 GNSGAEDGGAEAQS---SKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFS
270 280 290 300 310 320
910 920 930 940 950 960
pF1KF0 VAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNH
:: ::::::::::. :. :.: ::...:.:.:::::.:.:::..: : :::::::::
NP_056 EEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNH
330 340 350 360 370 380
970 980 990 1000 1010 1020
pF1KF0 PGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTT
:.::.::. : : .:: .:::::::::.::::..:::::::::::::::::::::::::
NP_056 PNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTH
390 400 410 420 430 440
1030 1040 1050 1060 1070 1080
pF1KF0 QEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIH
.: :.....:: .:::::: :::::::.::.:::::.:: :: ::: :.: ::::::.
NP_056 PQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIY
450 460 470 480 490 500
1090 1100 1110 1120 1130 1140
pF1KF0 SGELTKITK-QGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRD
:::::..:. :.::::: ::::::::. :::::::::.:::::::::: .:.::: ::.:
NP_056 SGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKD
510 520 530 540 550 560
1150 1160 1170 1180 1190 1200
pF1KF0 KDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISENQ
.: ..:.::::.: .: . .:.:..: :.: :::.: : ::..:: :.: :. :.: :
NP_056 RDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQ
570 580 590 600 610 620
1210 1220 1230 1240 1250 1260
pF1KF0 KKLAMLNAQKAG-HGKSKGYNR-CPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKR
.: :::::.: :: :. .: : .. .:.: ..:.. :::::. ::::.:
NP_056 RKQAMLNASKQQVTGKPKAVGRPCYLT---------RQKHPALPSNRPQQQVLVLAEPRR
630 640 650 660 670
1270
pF1KF0 KSSLFWHTFNRLTPFRK
: : :::...::.::::
NP_056 KPSTFWHSISRLAPFRK
680 690
>>XP_005263738 (OMIM: 605216) PREDICTED: rho guanine nuc (1876 aa)
initn: 2338 init1: 1140 opt: 2352 Z-score: 1287.1 bits: 250.9 E(85289): 6e-65
Smith-Waterman score: 2458; 39.4% identity (62.8% similar) in 1254 aa overlap (77-1277:677-1876)
50 60 70 80 90 100
pF1KF0 CGNGVCGCSPGGDTDTQEAKLSPAKLVRLFSTSRKRT--GAHPERPHSMVLVGNSSTWNT
: .: .: : . : : . . ..... .
XP_005 NAGPVPETLPRDFPKERPESPLSTGETPCESPTRGKTPAGNECELPAAPIQGAGDGALQR
650 660 670 680 690 700
110 120 130 140 150 160
pF1KF0 LASFRKMGSFKKLKSSVLKGIQSREGSNACSKGEASEHGLGKSIPNGAVPG-AQASRGS-
.:. ..: ... . ...: . .::. : :. :. : : : :.::.
XP_005 VAQAAELGRVLVPQAASEETPSTEEPPGERLRGESRSSGSGERGPEEAPEGGAAAARGQR
710 720 730 740 750 760
170 180 190 200 210 220
pF1KF0 PLAPGPACGALRPAE--WGTLDGSDLEDTDDAFQRSTHRSRSLRRAYGLGRICLLDAPQN
: .: ::.: . : :.. .:.. : :.:. :: ..: .
XP_005 PRVP-----ALEPPQPPRGLRKGAQEPGKRPTFSKVT----SFRK----GRPLATESPGG
770 780 790 800 810
230 240 250 260 270
pF1KF0 HATPTIATGQVPAVC-EILVRDPENNSMGYRRSKSTDNLAFLKKSSFKRKSTSNLADLRT
.:: . . : : :. . : ... : :.. . . .: ::
XP_005 VPAPTTEGRRWGSSGPEGLPRENPPAAAG----RDAPPLHHGDASAWPEFVPQAAGD-RT
820 830 840 850 860
280 290 300 310 320 330
pF1KF0 AHDARVPQR----TLSSSSTDSQKLGSGRTKRWRSPIRAKDFDRVFKLVSNVTEA-AWRR
: : . . :.: . .:.. .. : : .. .::. . . : :: :. . ..
XP_005 AGPAGAGHTGTSGDLGSRGPSSESCNAKRLKTTEKKLRAR-LALAHKTFSNFIESIVLEK
870 880 890 900 910 920
340 350 360 370 380 390
pF1KF0 ESPRSGAPSPGEASLRLQAHSRLHDDYSRRVSRSTEQDSRRGGAVMHGTTATCTVAPGFG
:. . .:: .. . .:::.. : .: . : . ... . ...:.
XP_005 ENTHERSPSSPKGE---KEKSRLRQGSWRAFLKSKDAGSPKKPTLVSLPLGPEVLSPAET
930 940 950 960 970 980
400 410 420 430 440 450
pF1KF0 SATSKGPHLDADTAVFPLETKSSWAVESDSSCTCSSLPSPIVQDVLSKDSCDPNAGSQLT
.. . : . :: .. :: :. ::: :: . . .:. :
XP_005 DSHCEERAEDKEGYVF----SDHWAPPLASTPLSSSLVSP-----EHRRKSEPTIKCTAT
990 1000 1010 1020 1030
460 470 480 490 500 510
pF1KF0 FDPEQP-PTPLRPTTPKPQSPQSPQSPGAGSASCHSNHSA--LSANSEESEGRAEEPAQR
. . :. . : :: ::.. :: : . :: :. .. . : :
XP_005 QEGGRYLPSGIFPEKSWLASPGSPRAQQAGIAHTLPSSSACCLAYENPGTPCRPTSPKPL
1040 1050 1060 1070 1080 1090
520 530 540 550 560
pF1KF0 EPGPVSLQDPLEATHGDEGSKDLLVNIGV------AAGPEEKEKEEVVPDGPWR-----R
: : . . :. . .:: .:..: ..: :. : .: : .
XP_005 SPRPSAQRMGLH--YPGRGSAISMVSLGSYSYVDSSSGDPERPK---IPKGQTSFLLSLQ
1100 1110 1120 1130 1140 1150
570 580 590 600 610
pF1KF0 SSSQDEERTEAQRTPKRRWGSGRRP--RPRPFSD----YGQLASR--SLSIPEDSVAADP
. .:::.. :... . : : : : : :. . . :.. : : . . .:
XP_005 TLNQDEQKEESREGGQGPRGLGTVPWLRDLPGSENHMPWEEPAGEKPSCSHSQKAFHMEP
1160 1170 1180 1190 1200 1210
620 630 640 650 660
pF1KF0 QKEDRVDED--PQASMT-SASPEDQNAPVGCPKGARRRRPISVIGGVSLYGTNQTEELDN
.. : : . :: .:: . :.: .: :.:: . : : : ..:..
XP_005 AQKPCFTTDMVTWALLCISAETVRGEAP-SQPRGIPHRSPVSV-DDLWLEKT-QRKKLQK
1220 1230 1240 1250 1260
670 680 690 700 710
pF1KF0 LLTQPASRPPMPA-HQ----------VPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMR
.. : . : :. . .... : .:::.: ::...: ..
XP_005 Q-AHVERRLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTP
1270 1280 1290 1300 1310 1320
720 730 740 750 760 770
pF1KF0 ASNVSSDGGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGG--EQLAINELISDGNVVC
.. . ::. . .. .:. :::::. :.:: ..: .: .::: ::::::::::::.:::
XP_005 GTAMP-DGALDTAVCADEVGSEEDL-YDDLHSSSHHYSHPGGGGEQLAINELISDGSVVC
1330 1340 1350 1360 1370 1380
780 790 800 810 820 830
pF1KF0 AEALWDHVTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELS
:::::::::::::::::::::::.:..:.:..::::: : :.:::::::::::::.: .
XP_005 AEALWDHVTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPA
1390 1400 1410 1420 1430 1440
840 850 860 870 880 890
pF1KF0 ENSSSTPSEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCR
.... .. :... . .:.::::::: ::..::: ::::::::::::.::::
XP_005 DDDAPLAGNSGAEDGGAEAQS---SKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCR
1450 1460 1470 1480 1490 1500
900 910 920 930 940 950
pF1KF0 KHTGMFTVAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIY
:.. ::. :: ::::::::::. :. :.: ::...:.:.:::::.:.:::..: : ::
XP_005 KRADMFSEEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIY
1510 1520 1530 1540 1550 1560
960 970 980 990 1000 1010
pF1KF0 SEYCNNHPGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLA
::::::::.::.::. : : .:: .:::::::::.::::..:::::::::::::::::::
XP_005 SEYCNNHPNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLA
1570 1580 1590 1600 1610 1620
1020 1030 1040 1050 1060 1070
pF1KF0 ELLKYTTQEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILD
:::::: .: :.....:: .:::::: :::::::.::.:::::.:: :: ::: :.:
XP_005 ELLKYTHPQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLV
1630 1640 1650 1660 1670 1680
1080 1090 1100 1110 1120 1130
pF1KF0 RSSELIHSGELTKITK-QGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELV
::::::.:::::..:. :.::::: ::::::::. :::::::::.:::::::::: .:.:
XP_005 RSSELIYSGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVV
1690 1700 1710 1720 1730 1740
1140 1150 1160 1170 1180 1190
pF1KF0 DLGDGRDKDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMG
:: ::.:.: ..:.::::.: .: . .:.:..: :.: :::.: : ::..:: :.: :
XP_005 DLEDGKDRDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETG
1750 1760 1770 1780 1790 1800
1200 1210 1220 1230 1240 1250
pF1KF0 MEISENQKKLAMLNAQKAG-HGKSKGYNR-CPVAPPHQGLHPIHQRHITMPTSVPQQQVF
. :.: :.: :::::.: :: :. .: : .. .:.: ..:.. :::::.
XP_005 FSITELQRKQAMLNASKQQVTGKPKAVGRPCYLT---------RQKHPALPSNRPQQQVL
1810 1820 1830 1840 1850
1260 1270
pF1KF0 GLAEPKRKSSLFWHTFNRLTPFRK
::::.:: : :::...::.::::
XP_005 VLAEPRRKPSTFWHSISRLAPFRK
1860 1870
>>XP_005263744 (OMIM: 605216) PREDICTED: rho guanine nuc (567 aa)
initn: 2309 init1: 1140 opt: 2320 Z-score: 1277.0 bits: 247.3 E(85289): 2.2e-64
Smith-Waterman score: 2320; 61.5% identity (82.6% similar) in 564 aa overlap (719-1277:17-567)
690 700 710 720 730 740
pF1KF0 KAVSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSDGGTEPSALVDDNGSEEDFSYEDL
:. . ::. . .. .:. :::::. :.::
XP_005 MRGAVSRSWSLESLRSATAAMPDGALDTAVCADEVGSEEDL-YDDL
10 20 30 40
750 760 770 780 790 800
pF1KF0 CQASPRYLQPGG--EQLAINELISDGNVVCAEALWDHVTMDDQELGFKAGDVIQVLEASN
..: .: .::: ::::::::::::.::::::::::::::::::::::::::.:..:.:
XP_005 HSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDHVTMDDQELGFKAGDVIEVMDATN
50 60 70 80 90 100
810 820 830 840 850 860
pF1KF0 KDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTPSEEQDEEASQSRHRHCENKQQMR
..::::: : :.:::::::::::::.: ..... .. :... . .:.:::
XP_005 REWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLAGNSGAEDGGAEAQS---SKDQMR
110 120 130 140 150 160
870 880 890 900 910 920
pF1KF0 TNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFTVAQLATIFGNIEDIYKFQRKFLK
:::: ::..::: ::::::::::::.:::::.. ::. :: ::::::::::. :. :.:
XP_005 TNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFSEEQLRTIFGNIEDIYRCQKAFVK
170 180 190 200 210 220
930 940 950 960 970 980
pF1KF0 DLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNHPGACLELANLMKQGKYRHFFEAC
::...:.:.:::::.:.:::..: : ::::::::::.::.::. : : .:: .:::::
XP_005 ALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNHPNACVELSRLTKLSKYVYFFEAC
230 240 250 260 270 280
990 1000 1010 1020 1030 1040
pF1KF0 RLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTTQEHGDYSNIKAAYEAMKNVACLI
::::.::::..::::::::::::::::::::::::: .: :.....:: .:::::: ::
XP_005 RLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTHPQHRDFKDVEAALHAMKNVAQLI
290 300 310 320 330 340
1050 1060 1070 1080 1090 1100
pF1KF0 NERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIHSGELTKITK-QGKSQQRTFFLFD
:::::.::.:::::.:: :: ::: :.: ::::::.:::::..:. :.::::: :::::
XP_005 NERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIYSGELTRVTQPQAKSQQRMFFLFD
350 360 370 380 390 400
1110 1120 1130 1140 1150 1160
pF1KF0 HQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRDKDCNLSVKNAFKLVSRTTDEVYL
:::. :::::::::.:::::::::: .:.::: ::.:.: ..:.::::.: .: . .:
XP_005 HQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKDRDLHVSIKNAFRLHRGATGDSHL
410 420 430 440 450 460
1170 1180 1190 1200 1210 1220
pF1KF0 FCAKKQEDKARWLQACADERRRVQEDKEMGMEISENQKKLAMLNAQKAG-HGKSKGYNR-
.:..: :.: :::.: : ::..:: :.: :. :.: :.: :::::.: :: :. .:
XP_005 LCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQRKQAMLNASKQQVTGKPKAVGRP
470 480 490 500 510 520
1230 1240 1250 1260 1270
pF1KF0 CPVAPPHQGLHPIHQRHITMPTSVPQQQVFGLAEPKRKSSLFWHTFNRLTPFRK
: .. .:.: ..:.. :::::. ::::.:: : :::...::.::::
XP_005 CYLT---------RQKHPALPSNRPQQQVLVLAEPRRKPSTFWHSISRLAPFRK
530 540 550 560
>>NP_127462 (OMIM: 605216) rho guanine nucleotide exchan (670 aa)
initn: 1611 init1: 1140 opt: 2225 Z-score: 1224.6 bits: 237.9 E(85289): 1.8e-61
Smith-Waterman score: 2225; 60.5% identity (81.1% similar) in 562 aa overlap (696-1251:118-668)
670 680 690 700 710 720
pF1KF0 ELDNLLTQPASRPPMPAHQVPPYKAVSARFRPFTFSQSTPIGLDRVGRRRQMRASNVSSD
: .:::.: ::...: .. .. . :
NP_127 RLHIGAVHKDGVKCWRKTIITSPESLNLPRRSHPLSQSAPTGLNHMGWPEHTPGTAMP-D
90 100 110 120 130 140
730 740 750 760 770 780
pF1KF0 GGTEPSALVDDNGSEEDFSYEDLCQASPRYLQPGG--EQLAINELISDGNVVCAEALWDH
:. . .. .:. :::::. :.:: ..: .: .::: ::::::::::::.::::::::::
NP_127 GALDTAVCADEVGSEEDL-YDDLHSSSHHYSHPGGGGEQLAINELISDGSVVCAEALWDH
150 160 170 180 190 200
790 800 810 820 830 840
pF1KF0 VTMDDQELGFKAGDVIQVLEASNKDWWWGRSEDKEAWFPASFVRLRVNQEELSENSSSTP
::::::::::::::::.:..:.:..::::: : :.:::::::::::::.: .....
NP_127 VTMDDQELGFKAGDVIEVMDATNREWWWGRVADGEGWFPASFVRLRVNQDEPADDDAPLA
210 220 230 240 250 260
850 860 870 880 890 900
pF1KF0 SEEQDEEASQSRHRHCENKQQMRTNVIREIMDTERVYIKHLRDICEGYIRQCRKHTGMFT
.. :... . .:.::::::: ::..::: ::::::::::::.:::::.. ::.
NP_127 GNSGAEDGGAEAQ---SSKDQMRTNVINEILSTERDYIKHLRDICEGYVRQCRKRADMFS
270 280 290 300 310 320
910 920 930 940 950 960
pF1KF0 VAQLATIFGNIEDIYKFQRKFLKDLEKQYNKEEPHLSEIGSCFLQNQEGFAIYSEYCNNH
:: ::::::::::. :. :.: ::...:.:.:::::.:.:::..: : :::::::::
NP_127 EEQLRTIFGNIEDIYRCQKAFVKALEQRFNRERPHLSELGACFLEHQADFQIYSEYCNNH
330 340 350 360 370 380
970 980 990 1000 1010 1020
pF1KF0 PGACLELANLMKQGKYRHFFEACRLLQQMIDIAIDGFLLTPVQKICKYPLQLAELLKYTT
:.::.::. : : .:: .:::::::::.::::..:::::::::::::::::::::::::
NP_127 PNACVELSRLTKLSKYVYFFEACRLLQKMIDISLDGFLLTPVQKICKYPLQLAELLKYTH
390 400 410 420 430 440
1030 1040 1050 1060 1070 1080
pF1KF0 QEHGDYSNIKAAYEAMKNVACLINERKRKLESIDKIARWQVSIVGWEGLDILDRSSELIH
.: :.....:: .:::::: :::::::.::.:::::.:: :: ::: :.: ::::::.
NP_127 PQHRDFKDVEAALHAMKNVAQLINERKRRLENIDKIAQWQSSIEDWEGEDLLVRSSELIY
450 460 470 480 490 500
1090 1100 1110 1120 1130 1140
pF1KF0 SGELTKITK-QGKSQQRTFFLFDHQLVSCKKDLLRRDMLYYKGRLDMDEMELVDLGDGRD
:::::..:. :.::::: ::::::::. :::::::::.:::::::::: .:.::: ::.:
NP_127 SGELTRVTQPQAKSQQRMFFLFDHQLIYCKKDLLRRDVLYYKGRLDMDGLEVVDLEDGKD
510 520 530 540 550 560
1150 1160 1170 1180 1190 1200
pF1KF0 KDCNLSVKNAFKLVSRTTDEVYLFCAKKQEDKARWLQACADERRRVQEDKEMGMEISENQ
.: ..:.::::.: .: . .:.:..: :.: :::.: : ::..:: :.: :. :.: :
NP_127 RDLHVSIKNAFRLHRGATGDSHLLCTRKPEQKQRWLKAFAREREQVQLDQETGFSITELQ
570 580 590 600 610 620
1210 1220 1230 1240 1250
pF1KF0 KKLAMLNAQKAG-HGKSKGYNRCPVAPPHQ--GLHPIHQRHITMPTSVPQQQVFGLAEPK
.: :::::.: :: :: : .::: . : .: .: : ::.:
NP_127 RKQAMLNASKQQVTGKPKG--RRTAAPPPRLPGPYPAD----IIPFSEPQSQAS
630 640 650 660 670
1260 1270
pF1KF0 RKSSLFWHTFNRLTPFRK
1277 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 19:26:05 2016 done: Thu Nov 3 19:26:07 2016
Total Scan time: 13.100 Total Display time: 0.320
Function used was FASTA [36.3.4 Apr, 2011]