Result of FASTA (omim) for
pFN21ASDA0396
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KSDA0396, 627 aa
1>>>pF1KSDA0396 627 - 627 aa - 627 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.6875+/-0.000778; mu= 6.1412+/- 0.047
mean_var=219.6157+/-48.752, 0's: 0 Z-trim(105.9): 626 B-trim: 576 in 2/50
Lambda= 0.086545
statistics sampled from 13238 (14015) to 13238 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.491), E-opt: 0.2 (0.164), width: 16
Scan time: 9.280
The best scores are: opt bits E(85289)
NP_056137 (OMIM: 613539) protein fem-1 homolog B [ ( 627) 4127 530.4 7.4e-150
XP_016877348 (OMIM: 613539) PREDICTED: protein fem ( 469) 3111 403.4 9.4e-112
XP_005272092 (OMIM: 608767) PREDICTED: protein fem ( 617) 1387 188.2 7.1e-47
NP_064562 (OMIM: 608767) protein fem-1 homolog C [ ( 617) 1387 188.2 7.1e-47
XP_016865136 (OMIM: 608767) PREDICTED: protein fem ( 464) 831 118.7 4.6e-26
NP_061178 (OMIM: 613538) protein fem-1 homolog A [ ( 669) 672 99.0 5.6e-20
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 355 59.9 8.6e-08
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 355 59.9 8.7e-08
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 355 59.9 8.7e-08
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 355 59.9 8.8e-08
XP_011542805 (OMIM: 182900,612641) PREDICTED: anky (1791) 355 59.9 8.9e-08
XP_016868817 (OMIM: 182900,612641) PREDICTED: anky (1792) 355 59.9 8.9e-08
XP_016868816 (OMIM: 182900,612641) PREDICTED: anky (1807) 355 59.9 8.9e-08
NP_065208 (OMIM: 182900,612641) ankyrin-1 isoform (1856) 355 59.9 9.1e-08
NP_000028 (OMIM: 182900,612641) ankyrin-1 isoform (1880) 355 59.9 9.2e-08
NP_065209 (OMIM: 182900,612641) ankyrin-1 isoform (1881) 355 59.9 9.2e-08
XP_011542804 (OMIM: 182900,612641) PREDICTED: anky (1889) 355 59.9 9.2e-08
XP_016868815 (OMIM: 182900,612641) PREDICTED: anky (1892) 355 59.9 9.2e-08
NP_001135918 (OMIM: 182900,612641) ankyrin-1 isofo (1897) 355 59.9 9.2e-08
XP_016868814 (OMIM: 182900,612641) PREDICTED: anky (1908) 355 59.9 9.3e-08
XP_011542803 (OMIM: 182900,612641) PREDICTED: anky (1913) 355 59.9 9.3e-08
XP_011542802 (OMIM: 182900,612641) PREDICTED: anky (1914) 355 59.9 9.3e-08
XP_005273533 (OMIM: 182900,612641) PREDICTED: anky (1921) 355 59.9 9.3e-08
XP_016868813 (OMIM: 182900,612641) PREDICTED: anky (1922) 355 59.9 9.3e-08
XP_016868812 (OMIM: 182900,612641) PREDICTED: anky (1936) 355 59.9 9.3e-08
XP_016868811 (OMIM: 182900,612641) PREDICTED: anky (1937) 355 59.9 9.3e-08
XP_016868810 (OMIM: 182900,612641) PREDICTED: anky (1940) 355 59.9 9.4e-08
XP_011542798 (OMIM: 182900,612641) PREDICTED: anky (1944) 355 59.9 9.4e-08
XP_016868809 (OMIM: 182900,612641) PREDICTED: anky (1946) 355 59.9 9.4e-08
XP_011542797 (OMIM: 182900,612641) PREDICTED: anky (1953) 355 59.9 9.4e-08
XP_011542796 (OMIM: 182900,612641) PREDICTED: anky (1954) 355 59.9 9.4e-08
XP_016868808 (OMIM: 182900,612641) PREDICTED: anky (1961) 355 59.9 9.4e-08
XP_011542793 (OMIM: 182900,612641) PREDICTED: anky (1968) 355 60.0 9.4e-08
XP_011542792 (OMIM: 182900,612641) PREDICTED: anky (1969) 355 60.0 9.4e-08
NP_065690 (OMIM: 263650,605706) receptor-interacti ( 784) 346 58.4 1.1e-07
XP_016863601 (OMIM: 106410,600919) PREDICTED: anky (1689) 341 58.1 2.9e-07
XP_016863597 (OMIM: 106410,600919) PREDICTED: anky (1772) 341 58.2 3e-07
XP_016863600 (OMIM: 106410,600919) PREDICTED: anky (1755) 339 57.9 3.5e-07
XP_016863599 (OMIM: 106410,600919) PREDICTED: anky (1763) 339 57.9 3.5e-07
XP_016863598 (OMIM: 106410,600919) PREDICTED: anky (1770) 339 57.9 3.5e-07
XP_016863596 (OMIM: 106410,600919) PREDICTED: anky (1797) 339 57.9 3.6e-07
XP_016863595 (OMIM: 106410,600919) PREDICTED: anky (1806) 339 57.9 3.6e-07
XP_016863594 (OMIM: 106410,600919) PREDICTED: anky (1810) 339 57.9 3.6e-07
XP_016863592 (OMIM: 106410,600919) PREDICTED: anky (1816) 339 57.9 3.6e-07
XP_016863593 (OMIM: 106410,600919) PREDICTED: anky (1818) 339 57.9 3.6e-07
XP_016863591 (OMIM: 106410,600919) PREDICTED: anky (1838) 339 57.9 3.6e-07
XP_016863590 (OMIM: 106410,600919) PREDICTED: anky (1839) 339 57.9 3.6e-07
XP_016863589 (OMIM: 106410,600919) PREDICTED: anky (1846) 339 57.9 3.6e-07
XP_016863588 (OMIM: 106410,600919) PREDICTED: anky (1850) 339 57.9 3.6e-07
XP_016863587 (OMIM: 106410,600919) PREDICTED: anky (1851) 339 57.9 3.6e-07
>>NP_056137 (OMIM: 613539) protein fem-1 homolog B [Homo (627 aa)
initn: 4127 init1: 4127 opt: 4127 Z-score: 2811.4 bits: 530.4 E(85289): 7.4e-150
Smith-Waterman score: 4127; 100.0% identity (100.0% similar) in 627 aa overlap (1-627:1-627)
10 20 30 40 50 60
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
10 20 30 40 50 60
70 80 90 100 110 120
pF1KSD VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KSD NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KSD NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KSD HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIH
250 260 270 280 290 300
310 320 330 340 350 360
pF1KSD AYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 AYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KSD EQCIKLWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 EQCIKLWLHALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KSD SMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 SMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPR
430 440 450 460 470 480
490 500 510 520 530 540
pF1KSD TREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 TREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIV
490 500 510 520 530 540
550 560 570 580 590 600
pF1KSD QYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 QYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCL
550 560 570 580 590 600
610 620
pF1KSD AARAVRANDINYQDQIPRTLEEFVGFH
:::::::::::::::::::::::::::
NP_056 AARAVRANDINYQDQIPRTLEEFVGFH
610 620
>>XP_016877348 (OMIM: 613539) PREDICTED: protein fem-1 h (469 aa)
initn: 3111 init1: 3111 opt: 3111 Z-score: 2127.3 bits: 403.4 E(85289): 9.4e-112
Smith-Waterman score: 3111; 100.0% identity (100.0% similar) in 469 aa overlap (159-627:1-469)
130 140 150 160 170 180
pF1KSD CFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGA
::::::::::::::::::::::::::::::
XP_016 MIAAYKGHTDVVRYLLEQRADPNAKAHCGA
10 20 30
190 200 210 220 230 240
pF1KSD TALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCDRRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLSHADCDRRS
40 50 60 70 80 90
250 260 270 280 290 300
pF1KSD RIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTEC
100 110 120 130 140 150
310 320 330 340 350 360
pF1KSD RNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIKLWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIKLWL
160 170 180 190 200 210
370 380 390 400 410 420
pF1KSD HALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNRVKNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HALHLRQKGNRNTHKDLLRFAQVFSQMIHLNETVKAPDIECVLRCSVLEIEQSMNRVKNI
220 230 240 250 260 270
430 440 450 460 470 480
pF1KSD SDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPRTREGFTLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNLIHLDPRTREGFTLL
280 290 300 310 320 330
490 500 510 520 530 540
pF1KSD HLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIVQYNRPISD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIVQYNRPISD
340 350 360 370 380 390
550 560 570 580 590 600
pF1KSD FLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCLAARAVRAN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLTLHSIIISLVEAGAHTDMTNKQNKTPLDKSTTGVSEILLKTQMKMSLKCLAARAVRAN
400 410 420 430 440 450
610 620
pF1KSD DINYQDQIPRTLEEFVGFH
:::::::::::::::::::
XP_016 DINYQDQIPRTLEEFVGFH
460
>>XP_005272092 (OMIM: 608767) PREDICTED: protein fem-1 h (617 aa)
initn: 1212 init1: 725 opt: 1387 Z-score: 962.5 bits: 188.2 E(85289): 7.1e-47
Smith-Waterman score: 1438; 40.7% identity (69.9% similar) in 634 aa overlap (8-627:7-616)
10 20 30 40 50 60
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
:..:: .::. :. :: ..:. .. :.. . .: .:::..::: ::
XP_005 MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLIS--EKTNG--ATPLLMAARYGHLD
10 20 30 40 50
70 80 90 100 110 120
pF1KSD VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
.:..:::. .. . :.: ::: .:.:: :: :..:::..::. :..:::.::.::.:
XP_005 MVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
::::::::::::.:.:::::::..:.. ..:.. .:::::. :::: ....::::. ::
XP_005 NSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
: :. : :::: ::.: .::.: :. . : . .:.::::: :. . ....:..:
XP_005 NRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTH
180 190 200 210 220 230
250 260 270 280 290
pF1KSD HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPP--
::. .. ::.:::::::.:.. .. :.. . .: :: :..: ::. : : :
XP_005 HAQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPV-PQTL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD IHAYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNM
: :: : . .:::.. : : ..:..:..:::::: .. :.:. : ::::::::.
XP_005 IMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSG
300 310 320 330 340 350
360 370 380 390 400
pF1KSD EFEQCIKLWLHALHLRQKG----NRNTHKDLLRFAQVFSQMIH------LNETVKAPDIE
.:..::.:: .:: ..:.. . : ..:: ::..:: :.. :. :: :.
XP_005 NFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLM
360 370 380 390 400 410
410 420 430 440 450 460
pF1KSD CVLRCSVLEIEQSMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCS-EEDQCKI
.: ::::::....... .: : : .:.:.:. :. :. :.:. :
XP_005 GILCKSVLEIERAIKQTQCPADPLQLNK------ALSIILHLICLLEKVPCTLEQDHFK-
420 430 440 450 460
470 480 490 500 510 520
pF1KSD NKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNA
.. :: ...: :: ...:. :::::..:: ::.::. :: .:..:::.::.
XP_005 KQTIYRFLKLHPRGKNNFSPLHLAVDKNTTC--VGRYPVCKFPSLQVTAILIECGADVNV
470 480 490 500 510 520
530 540 550 560 570 580
pF1KSD VDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDK-STTGVSE
:.. :: ::: . :.: :...: :...::: : :: ...: : . ...
XP_005 RDSDDNSPLHIAALNNHP--DIMNL------LIKSGAHFDATNLHKQTASDLLDEKEIAK
530 540 550 560 570
590 600 610 620
pF1KSD ILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH
:.. . .:.:::::.. . : :. .::. :: ::..:
XP_005 NLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
580 590 600 610
>>NP_064562 (OMIM: 608767) protein fem-1 homolog C [Homo (617 aa)
initn: 1212 init1: 725 opt: 1387 Z-score: 962.5 bits: 188.2 E(85289): 7.1e-47
Smith-Waterman score: 1438; 40.7% identity (69.9% similar) in 634 aa overlap (8-627:7-616)
10 20 30 40 50 60
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
:..:: .::. :. :: ..:. .. :.. . .: .:::..::: ::
NP_064 MDLKTAVFNAARDGKLRLLTKLLASKSKEEVSSLIS--EKTNG--ATPLLMAARYGHLD
10 20 30 40 50
70 80 90 100 110 120
pF1KSD VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
.:..:::. .. . :.: ::: .:.:: :: :..:::..::. :..:::.::.::.:
NP_064 MVEFLLEQCSASIEVGGSVNFDGETIEGAPPLWAASAAGHLKVVQSLLNHGASVNNTTLT
60 70 80 90 100 110
130 140 150 160 170 180
pF1KSD NSTPLRAACFDGRLDIVKYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADP
::::::::::::.:.:::::::..:.. ..:.. .:::::. :::: ....::::. ::
NP_064 NSTPLRAACFDGHLEIVKYLVEHKADLEVSNRHGHTCLMISCYKGHKEIAQYLLEKGADV
120 130 140 150 160 170
190 200 210 220 230 240
pF1KSD NAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLLS
: :. : :::: ::.: .::.: :. . : . .:.::::: :. . ....:..:
NP_064 NRKSVKGNTALHDCAESGSLDIMKMLLMYCAKMEKDGYGMTPLLSASVTGHTNIVDFLTH
180 190 200 210 220 230
250 260 270 280 290
pF1KSD HADCDRRSRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPP--
::. .. ::.:::::::.:.. .. :.. . .: :: :..: ::. : : :
NP_064 HAQTSKTERINALELLGATFVDKKR--DLLGALKYWKKAMNMRYSDRTNIISKPV-PQTL
240 250 260 270 280 290
300 310 320 330 340 350
pF1KSD IHAYGNRTECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNM
: :: : . .:::.. : : ..:..:..:::::: .. :.:. : ::::::::.
NP_064 IMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSG
300 310 320 330 340 350
360 370 380 390 400
pF1KSD EFEQCIKLWLHALHLRQKG----NRNTHKDLLRFAQVFSQMIH------LNETVKAPDIE
.:..::.:: .:: ..:.. . : ..:: ::..:: :.. :. :: :.
NP_064 NFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAELFSFMLQDRAKGLLGTTVTFDDLM
360 370 380 390 400 410
410 420 430 440 450 460
pF1KSD CVLRCSVLEIEQSMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCS-EEDQCKI
.: ::::::....... .: : : .:.:.:. :. :. :.:. :
NP_064 GILCKSVLEIERAIKQTQCPADPLQLNK------ALSIILHLICLLEKVPCTLEQDHFK-
420 430 440 450 460
470 480 490 500 510 520
pF1KSD NKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNA
.. :: ...: :: ...:. :::::..:: ::.::. :: .:..:::.::.
NP_064 KQTIYRFLKLHPRGKNNFSPLHLAVDKNTTC--VGRYPVCKFPSLQVTAILIECGADVNV
470 480 490 500 510 520
530 540 550 560 570 580
pF1KSD VDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTPLDK-STTGVSE
:.. :: ::: . :.: :...: :...::: : :: ...: : . ...
NP_064 RDSDDNSPLHIAALNNHP--DIMNL------LIKSGAHFDATNLHKQTASDLLDEKEIAK
530 540 550 560 570
590 600 610 620
pF1KSD ILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH
:.. . .:.:::::.. . : :. .::. :: ::..:
NP_064 NLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLETFVSLHR
580 590 600 610
>>XP_016865136 (OMIM: 608767) PREDICTED: protein fem-1 h (464 aa)
initn: 735 init1: 229 opt: 831 Z-score: 588.8 bits: 118.7 E(85289): 4.6e-26
Smith-Waterman score: 882; 37.6% identity (66.4% similar) in 455 aa overlap (187-627:29-463)
160 170 180 190 200 210
pF1KSD CLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVN
: :::: ::.: .::.: :. . : . .
XP_016 MLIEKVSKASTWLIFLLPKEHHIVFRSAGNTALHDCAESGSLDIMKMLLMYCAKMEKD
10 20 30 40 50
220 230 240 250 260 270
pF1KSD GHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIIKTYHYL
:.::::: :. . ....:..: ::. .. ::.:::::::.:.. .. :.. . .:
XP_016 GYGMTPLLSASVTGHTNIVDFLTHHAQTSKTERINALELLGATFVDKKR--DLLGALKYW
60 70 80 90 100 110
280 290 300 310 320 330
pF1KSD YLAMLERFQDGDNILEKEVLPP--IHAYGNRTECRNPQELESIRQDRDALHMEGLIVRER
:: :..: ::. : : : : :: : . .:::.. : : ..:..:..:::
XP_016 KKAMNMRYSDRTNIISKPV-PQTLIMAYDYAKEVNSAEELEGLIADPDEMRMQALLIRER
120 130 140 150 160 170
340 350 360 370 380 390
pF1KSD ILGADNIDVSHPIIYRGAVYADNMEFEQCIKLWLHALHLRQKG----NRNTHKDLLRFAQ
::: .. :.:. : ::::::::. .:..::.:: .:: ..:.. . : ..:: ::.
XP_016 ILGPSHPDTSYYIRYRGAVYADSGNFKRCINLWKYALDMQQSNLDPLSPMTASSLLSFAE
180 190 200 210 220 230
400 410 420 430 440
pF1KSD VFSQMIH------LNETVKAPDIECVLRCSVLEIEQSMNRVKNISDADVHNAMDNYECNL
.:: :.. :. :: :. .: ::::::....... .: : :
XP_016 LFSFMLQDRAKGLLGTTVTFDDLMGILCKSVLEIERAIKQTQCPADPLQLNKA------L
240 250 260 270 280
450 460 470 480 490 500
pF1KSD YTFLYLVCISTKTQCS-EEDQCKINKQIYNLIHLDPRTREGFTLLHLAVNSNTPVDDFHT
.:.:.:. :. :. :.:. : .. :: ...: :: ...:. :::::..:: .
XP_016 SIILHLICLLEKVPCTLEQDHFK-KQTIYRFLKLHPRGKNNFSPLHLAVDKNTTCVGRYP
290 300 310 320 330 340
510 520 530 540 550 560
pF1KSD NDVCSFPNALVTKLLLDCGAEVNAVDNEGNSALHIIVQYNRPISDFLTLHSIIISLVEAG
::.::. :: .:..:::.::. :.. :: ::: . :.: :...: :...:
XP_016 --VCKFPSLQVTAILIECGADVNVRDSDDNSPLHIAALNNHP--DIMNL------LIKSG
350 360 370 380 390
570 580 590 600 610 620
pF1KSD AHTDMTNKQNKTPLDK-STTGVSEILLKTQMKMSLKCLAARAVRANDINYQDQIPRTLEE
:: : :: ...: : . ... :.. . .:.:::::.. . : :. .::. ::
XP_016 AHFDATNLHKQTASDLLDEKEIAKNLIQPINHTTLQCLAARVIVNHRIYYKGHIPEKLET
400 410 420 430 440 450
pF1KSD FVGFH
::..:
XP_016 FVSLHR
460
>>NP_061178 (OMIM: 613538) protein fem-1 homolog A [Homo (669 aa)
initn: 1098 init1: 349 opt: 672 Z-score: 479.6 bits: 99.0 E(85289): 5.6e-20
Smith-Waterman score: 1191; 35.8% identity (62.9% similar) in 674 aa overlap (8-612:7-654)
10 20 30 40 50 60
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAK
::.:: .::. : :: .::. .. : : :. :: .:::.:::: ::
NP_061 MDLRTAVYNAARDGKLQLLQKLLSGRSREELDELTGEVA--GG--GTPLLIAARYGHLD
10 20 30 40 50
70 80 90 100 110 120
pF1KSD VVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVT
::. :... .... :.:.::: .:.:: :: :..:::..::. :. .::.::.:: :
NP_061 VVEYLVDRCGASVEAGGSVHFDGETIEGAPPLWAASAAGHLDVVRSLLRRGASVNRTTRT
60 70 80 90 100 110
130 140 150 160 170
pF1KSD NSTPLRAACFDGRLDIVKYLV-ENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRAD
::::::::::::.:..:.::: :..:.. .::.. .:::::. :::: ...:::::: :.
NP_061 NSTPLRAACFDGHLEVVRYLVGEHQADLEVANRHGHTCLMISCYKGHREIARYLLEQGAQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KSD PNAKAHCGATALHFAAEAGHIDIVKELIKWRAAIVVNGHGMTPLKVAAESCKADVVELLL
: .. : :::: ::.: ..:.. :. .: . .:.::::: .:. . ....:: :.
NP_061 VNRRSAKGNTALHDCAESGSLEILQLLLGCKARMERDGYGMTPLLAASVTGHTNIVEYLI
180 190 200 210 220 230
240
pF1KSD -------------------------------------------------SHADC---DRR
:. .: .:.
NP_061 QEQPGQEQVAGGEAQPGLPQEDPSTSQGCAQPQGAPCCSSSPEEPLNGESYESCCPTSRE
240 250 260 270 280 290
250 260 270 280 290 300
pF1KSD SRIEALELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPP--IHAYGNR
. .::::::::.... .. :.. . .. :: : : :. . . : :: . ::
NP_061 AAVEALELLGATYVDKKR--DLLGALKHWRRAMELRHQGGEYLPKPE--PPQLVLAYDYS
300 310 320 330 340 350
310 320 330 340 350 360
pF1KSD TECRNPQELESIRQDRDALHMEGLIVRERILGADNIDVSHPIIYRGAVYADNMEFEQCIK
: . .:::.. : : ..:..:..:::::: .. :.:. : ::::::::. .::.::.
NP_061 REVNTTEELEALITDPDEMRMQALLIRERILGPSHPDTSYYIRYRGAVYADSGNFERCIR
360 370 380 390 400 410
370 380 390 400 410
pF1KSD LWLHALHLRQKG----NRNTHKDLLRFAQVFSQMIH-------LNETVKAPDIECVLRCS
:: .:: ..:.. . : ...: ::..:: ... :. . :. :: .
NP_061 LWKYALDMQQSNLEPLSPMTASSFLSFAELFSYVLQDRAAKGSLGTQIGFADLMGVLTKG
420 430 440 450 460 470
420 430 440 450 460 470
pF1KSD VLEIEQSMNRVKNISDADVHNAMDNYECNLYTFLYLVCISTKTQCSEEDQCKINKQIYNL
: :.:.... .. .:. .. : .:.:. . :..:. .. .. .: :
NP_061 VREVERALQLPREPGDSA------QFTKALAIILHLLYLLEKVECTPSQEHLKHQTVYRL
480 490 500 510 520
480 490 500 510 520 530
pF1KSD IHLDPRTREGFTLLHLAVNSNTPVDDFHTNDVCSFPNALVTKLLLDCGAEVNAVDNEGNS
.. :: ..::: ::.::...: . : ::. :.:.::::::. .. : ..:.
NP_061 LKCAPRGKNGFTPLHMAVDKDT--TNVGRYPVGRFPSLHVVKVLLDCGADPDSRDFDNNT
530 540 550 560 570 580
540 550 560 570 580 590
pF1KSD ALHIIVQYNRPISDFLTLHSIIISLVEAGAHTDMTNKQNKTP---LDKSTTGVSEILLKT
::: .: : : .:. .:.::::: : :: .:: ::.. ... ..
NP_061 PLHIAAQNNCP--------AIMNALIEAGAHMDATNAFKKTAYELLDEKL--LARGTMQP
590 600 610 620 630
600 610 620
pF1KSD QMKMSLKCLAARAVRANDINYQDQIPRTLEEFVGFH
..:.::::::. : : :
NP_061 FNYVTLQCLAARALDKNKIPYKGFIPEDLEAFIELH
640 650 660
>>NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform 2 [H (1719 aa)
initn: 1280 init1: 273 opt: 355 Z-score: 260.8 bits: 59.9 E(85289): 8.6e-08
Smith-Waterman score: 387; 36.4% identity (65.4% similar) in 228 aa overlap (48-271:373-586)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :: ...:..:..::: .::
NP_065 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL--------KTG
350 360 370 380 390
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
. .:. . .: : : :. ::. .:: :...::. : ..: :::. : :. ...
NP_065 A-SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA
400 410 420 430 440 450
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:::..:.:... : :.: : :: :::..:. :::. :.:: . : : ::.::.
NP_065 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAARE
460 470 480 490 500 510
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAA-IVVNGHGMTPLKVAAESCKADVVELLL---SHADCDRRSRIEAL
::.. : :.. .:. .. .:.:::.:::. :. :.:::: .: . .. . :
NP_065 GHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL
520 530 540 550 560 570
260 270 280 290 300 310
pF1KSD ELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQE
.. : ..: ::.:
NP_065 HV-----AVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA
580 590 600 610 620
>--
initn: 238 init1: 238 opt: 307 Z-score: 228.5 bits: 53.9 E(85289): 5.5e-06
Smith-Waterman score: 307; 33.9% identity (66.1% similar) in 192 aa overlap (48-238:604-786)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :::......:.: :: : :
NP_065 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLL-------QYGG
580 590 600 610 620
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
.. .. ..:.: : :: :: :.: ::.:. :: : . .. :::. . .:.. ..
NP_065 SA--NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA
630 640 650 660 670 680
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:..... .. .... : : .:.. :. .:..::...:: :::.. : . :: ::.
NP_065 DVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ
690 700 710 720 730 740
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAAIV-VNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELL
:: ::: :.: :. :.. : ::: .: . .:...:
NP_065 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRM
750 760 770 780 790 800
260 270 280 290 300 310
pF1KSD GASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQELES
NP_065 SFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIPC
810 820 830 840 850 860
>--
initn: 384 init1: 213 opt: 288 Z-score: 215.6 bits: 51.5 E(85289): 2.8e-05
Smith-Waterman score: 288; 31.4% identity (60.6% similar) in 236 aa overlap (6-239:134-358)
10 20 30
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYL
: ..:.: ::. : . :. . .:
NP_065 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL
110 120 130 140 150 160
40 50 60 70 80 90
pF1KSD LGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCA
..: . .: : : ::::: .... .::.. . : : : : :
NP_065 INY-GTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT---------GFTPLHIA
170 180 190 200 210
100 110 120 130 140 150
pF1KSD AGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDN
: ...:..::...::.:: : .. :::. : : . .:. :.. .:.: .: .
NP_065 AHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL
220 230 240 250 260 270
160 170 180 190 200 210
pF1KSD TCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAI--
: : :: .::. . . ::.. : .::.. : . .:.::.. :.: :. :... : :
NP_065 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD
280 290 300 310 320 330
220 230 240 250 260 270
pF1KSD VVNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIIKTY
.. : .:::.:::. . :...::
NP_065 ITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLK
340 350 360 370 380 390
>>XP_011542807 (OMIM: 182900,612641) PREDICTED: ankyrin- (1751 aa)
initn: 1280 init1: 273 opt: 355 Z-score: 260.7 bits: 59.9 E(85289): 8.7e-08
Smith-Waterman score: 387; 36.4% identity (65.4% similar) in 228 aa overlap (48-271:406-619)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :: ...:..:..::: .::
XP_011 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL--------KTG
380 390 400 410 420
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
. .:. . .: : : :. ::. .:: :...::. : ..: :::. : :. ...
XP_011 A-SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA
430 440 450 460 470 480
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:::..:.:... : :.: : :: :::..:. :::. :.:: . : : ::.::.
XP_011 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAARE
490 500 510 520 530 540
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAA-IVVNGHGMTPLKVAAESCKADVVELLL---SHADCDRRSRIEAL
::.. : :.. .:. .. .:.:::.:::. :. :.:::: .: . .. . :
XP_011 GHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL
550 560 570 580 590 600
260 270 280 290 300 310
pF1KSD ELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQE
.. : ..: ::.:
XP_011 HV-----AVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA
610 620 630 640 650 660
>--
initn: 238 init1: 238 opt: 307 Z-score: 228.4 bits: 53.9 E(85289): 5.6e-06
Smith-Waterman score: 307; 33.9% identity (66.1% similar) in 192 aa overlap (48-238:637-819)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :::......:.: :: : :
XP_011 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLL-------QYGG
610 620 630 640 650
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
.. .. ..:.: : :: :: :.: ::.:. :: : . .. :::. . .:.. ..
XP_011 SA--NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA
660 670 680 690 700 710
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:..... .. .... : : .:.. :. .:..::...:: :::.. : . :: ::.
XP_011 DVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ
720 730 740 750 760 770
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAAIV-VNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELL
:: ::: :.: :. :.. : ::: .: . .:...:
XP_011 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRM
780 790 800 810 820 830
260 270 280 290 300 310
pF1KSD GASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQELES
XP_011 SFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIPC
840 850 860 870 880 890
>--
initn: 384 init1: 213 opt: 288 Z-score: 215.5 bits: 51.5 E(85289): 2.9e-05
Smith-Waterman score: 288; 31.4% identity (60.6% similar) in 236 aa overlap (6-239:167-391)
10 20 30
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYL
: ..:.: ::. : . :. . .:
XP_011 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL
140 150 160 170 180 190
40 50 60 70 80 90
pF1KSD LGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCA
..: . .: : : ::::: .... .::.. . : : : : :
XP_011 INY-GTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT---------GFTPLHIA
200 210 220 230 240
100 110 120 130 140 150
pF1KSD AGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDN
: ...:..::...::.:: : .. :::. : : . .:. :.. .:.: .: .
XP_011 AHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL
250 260 270 280 290 300
160 170 180 190 200 210
pF1KSD TCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAI--
: : :: .::. . . ::.. : .::.. : . .:.::.. :.: :. :... : :
XP_011 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD
310 320 330 340 350 360
220 230 240 250 260 270
pF1KSD VVNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIIKTY
.. : .:::.:::. . :...::
XP_011 ITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLK
370 380 390 400 410 420
>>XP_011542806 (OMIM: 182900,612641) PREDICTED: ankyrin- (1752 aa)
initn: 1280 init1: 273 opt: 355 Z-score: 260.7 bits: 59.9 E(85289): 8.7e-08
Smith-Waterman score: 387; 36.4% identity (65.4% similar) in 228 aa overlap (48-271:406-619)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :: ...:..:..::: .::
XP_011 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL--------KTG
380 390 400 410 420
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
. .:. . .: : : :. ::. .:: :...::. : ..: :::. : :. ...
XP_011 A-SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA
430 440 450 460 470 480
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:::..:.:... : :.: : :: :::..:. :::. :.:: . : : ::.::.
XP_011 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAARE
490 500 510 520 530 540
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAA-IVVNGHGMTPLKVAAESCKADVVELLL---SHADCDRRSRIEAL
::.. : :.. .:. .. .:.:::.:::. :. :.:::: .: . .. . :
XP_011 GHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL
550 560 570 580 590 600
260 270 280 290 300 310
pF1KSD ELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQE
.. : ..: ::.:
XP_011 HV-----AVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA
610 620 630 640 650 660
>--
initn: 238 init1: 238 opt: 307 Z-score: 228.4 bits: 53.9 E(85289): 5.6e-06
Smith-Waterman score: 307; 33.9% identity (66.1% similar) in 192 aa overlap (48-238:637-819)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :::......:.: :: : :
XP_011 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLL-------QYGG
610 620 630 640 650
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
.. .. ..:.: : :: :: :.: ::.:. :: : . .. :::. . .:.. ..
XP_011 SA--NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA
660 670 680 690 700 710
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:..... .. .... : : .:.. :. .:..::...:: :::.. : . :: ::.
XP_011 DVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ
720 730 740 750 760 770
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAAIV-VNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELL
:: ::: :.: :. :.. : ::: .: . .:...:
XP_011 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRM
780 790 800 810 820 830
260 270 280 290 300 310
pF1KSD GASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQELES
XP_011 SFPETVDEILDVSEDEGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVESPAIPRIPC
840 850 860 870 880 890
>--
initn: 384 init1: 213 opt: 288 Z-score: 215.5 bits: 51.5 E(85289): 2.9e-05
Smith-Waterman score: 288; 31.4% identity (60.6% similar) in 236 aa overlap (6-239:167-391)
10 20 30
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYL
: ..:.: ::. : . :. . .:
XP_011 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL
140 150 160 170 180 190
40 50 60 70 80 90
pF1KSD LGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCA
..: . .: : : ::::: .... .::.. . : : : : :
XP_011 INY-GTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT---------GFTPLHIA
200 210 220 230 240
100 110 120 130 140 150
pF1KSD AGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDN
: ...:..::...::.:: : .. :::. : : . .:. :.. .:.: .: .
XP_011 AHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL
250 260 270 280 290 300
160 170 180 190 200 210
pF1KSD TCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAI--
: : :: .::. . . ::.. : .::.. : . .:.::.. :.: :. :... : :
XP_011 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD
310 320 330 340 350 360
220 230 240 250 260 270
pF1KSD VVNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIIKTY
.. : .:::.:::. . :...::
XP_011 ITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLK
370 380 390 400 410 420
>>XP_016868818 (OMIM: 182900,612641) PREDICTED: ankyrin- (1759 aa)
initn: 1280 init1: 273 opt: 355 Z-score: 260.7 bits: 59.9 E(85289): 8.8e-08
Smith-Waterman score: 387; 36.4% identity (65.4% similar) in 228 aa overlap (48-271:406-619)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :: ...:..:..::: .::
XP_016 HVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL--------KTG
380 390 400 410 420
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
. .:. . .: : : :. ::. .:: :...::. : ..: :::. : :. ...
XP_016 A-SIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVA
430 440 450 460 470 480
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:::..:.:... : :.: : :: :::..:. :::. :.:: . : : ::.::.
XP_016 KYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAARE
490 500 510 520 530 540
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAA-IVVNGHGMTPLKVAAESCKADVVELLL---SHADCDRRSRIEAL
::.. : :.. .:. .. .:.:::.:::. :. :.:::: .: . .. . :
XP_016 GHVETVLALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPL
550 560 570 580 590 600
260 270 280 290 300 310
pF1KSD ELLGASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQE
.. : ..: ::.:
XP_016 HV-----AVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQYGGSA
610 620 630 640 650 660
>--
initn: 238 init1: 238 opt: 307 Z-score: 228.3 bits: 53.9 E(85289): 5.6e-06
Smith-Waterman score: 307; 33.9% identity (66.1% similar) in 192 aa overlap (48-238:637-819)
20 30 40 50 60 70
pF1KSD LTLAALLLNRSESDIRYLLGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTG
::: :::......:.: :: : :
XP_016 HVAVHHNNLDIVKLLLPRGGSPHSPAWNGYTPLHIAAKQNQVEVARSLL-------QYGG
610 620 630 640 650
80 90 100 110 120 130
pF1KSD TVRFDGYVIDGATALWCAAGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIV
.. .. ..:.: : :: :: :.: ::.:. :: : . .. :::. . .:.. ..
XP_016 SA--NAESVQGVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPVA
660 670 680 690 700 710
140 150 160 170 180 190
pF1KSD KYLVENNANISIANKYDNTCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEA
:..... .. .... : : .:.. :. .:..::...:: :::.. : . :: ::.
XP_016 DVLIKHGVMVDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQ
720 730 740 750 760 770
200 210 220 230 240 250
pF1KSD GHIDIVKELIKWRAAIV-VNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELL
:: ::: :.: :. :.. : ::: .: . .:...:
XP_016 GHTDIVTLLLKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLKVVTDETSFVLVSDKHRM
780 790 800 810 820 830
260 270 280 290 300 310
pF1KSD GASFANDRENYDIIKTYHYLYLAMLERFQDGDNILEKEVLPPIHAYGNRTECRNPQELES
XP_016 SFPETVDEILDVSEDEGTAHITIMGEELISFKAERRDSRDVDEEKELLDFVPKLDQVVES
840 850 860 870 880 890
>--
initn: 384 init1: 213 opt: 288 Z-score: 215.5 bits: 51.5 E(85289): 2.9e-05
Smith-Waterman score: 288; 31.4% identity (60.6% similar) in 236 aa overlap (6-239:167-391)
10 20 30
pF1KSD MEGLAGYVYKAASEGKVLTLAALLLNRSESDIRYL
: ..:.: ::. : . :. . .:
XP_016 VNAQSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHL
140 150 160 170 180 190
40 50 60 70 80 90
pF1KSD LGYVSQQGGQRSTPLIIAARNGHAKVVRLLLEHYRVQTQQTGTVRFDGYVIDGATALWCA
..: . .: : : ::::: .... .::.. . : : : : :
XP_016 INY-GTKGKVRLPALHIAARNDDTRTAAVLLQNDPNPDVLSKT---------GFTPLHIA
200 210 220 230 240
100 110 120 130 140 150
pF1KSD AGAGHFEVVKLLVSHGANVNHTTVTNSTPLRAACFDGRLDIVKYLVENNANISIANKYDN
: ...:..::...::.:: : .. :::. : : . .:. :.. .:.: .: .
XP_016 AHYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDEL
250 260 270 280 290 300
160 170 180 190 200 210
pF1KSD TCLMIAAYKGHTDVVRYLLEQRADPNAKAHCGATALHFAAEAGHIDIVKELIKWRAAI--
: : :: .::. . . ::.. : .::.. : . .:.::.. :.: :. :... : :
XP_016 TPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEIDD
310 320 330 340 350 360
220 230 240 250 260 270
pF1KSD VVNGHGMTPLKVAAESCKADVVELLLSHADCDRRSRIEALELLGASFANDRENYDIIKTY
.. : .:::.:::. . :...::
XP_016 ITLDH-LTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLLK
370 380 390 400 410 420
627 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 18:31:47 2016 done: Thu Nov 3 18:31:48 2016
Total Scan time: 9.280 Total Display time: 0.130
Function used was FASTA [36.3.4 Apr, 2011]