Result of FASTA (omim) for
pFN21AB5662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5662, 372 aa
1>>>pF1KB5662 372 - 372 aa - 372 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.3808+/-0.000364; mu= 1.4572+/- 0.023
mean_var=369.3764+/-78.452, 0's: 0 Z-trim(124.0): 916 B-trim: 2412 in 1/61
Lambda= 0.066733
statistics sampled from 43536 (44740) to 43536 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.806), E-opt: 0.2 (0.525), width: 16
Scan time: 9.250
The best scores are: opt bits E(85289)
NP_079471 (OMIM: 609461) tribbles homolog 1 isofor ( 372) 2529 256.8 5.7e-68
NP_001269914 (OMIM: 609461) tribbles homolog 1 iso ( 206) 1378 145.7 9e-35
NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo ( 343) 1266 135.2 2.2e-31
XP_016883478 (OMIM: 607898) PREDICTED: tribbles ho ( 385) 992 108.9 2e-23
NP_001288130 (OMIM: 607898) tribbles homolog 3 iso ( 385) 992 108.9 2e-23
NP_001288122 (OMIM: 607898) tribbles homolog 3 iso ( 358) 988 108.5 2.6e-23
NP_001288125 (OMIM: 607898) tribbles homolog 3 iso ( 358) 988 108.5 2.6e-23
NP_001288119 (OMIM: 607898) tribbles homolog 3 iso ( 358) 988 108.5 2.6e-23
NP_001288117 (OMIM: 607898) tribbles homolog 3 iso ( 358) 988 108.5 2.6e-23
NP_066981 (OMIM: 607898) tribbles homolog 3 isofor ( 358) 988 108.5 2.6e-23
NP_001269476 (OMIM: 609437) serine/threonine-prote ( 435) 421 54.0 7.8e-07
NP_114406 (OMIM: 609437) serine/threonine-protein ( 435) 421 54.0 7.8e-07
NP_001269475 (OMIM: 609437) serine/threonine-prote ( 440) 421 54.0 7.9e-07
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 422 54.4 1.1e-06
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 407 52.5 1.8e-06
NP_001094064 (OMIM: 612760) SNF-related serine/thr ( 765) 413 53.5 1.9e-06
XP_005265302 (OMIM: 612760) PREDICTED: SNF-related ( 765) 413 53.5 1.9e-06
NP_060189 (OMIM: 612760) SNF-related serine/threon ( 765) 413 53.5 1.9e-06
NP_006243 (OMIM: 600497) 5'-AMP-activated protein ( 552) 409 52.9 2e-06
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 407 52.8 2.5e-06
NP_001243618 (OMIM: 607025) maternal embryonic leu ( 619) 407 52.8 2.5e-06
XP_011516385 (OMIM: 607025) PREDICTED: maternal em ( 619) 407 52.8 2.5e-06
XP_011516386 (OMIM: 607025) PREDICTED: maternal em ( 619) 407 52.8 2.5e-06
XP_011516384 (OMIM: 607025) PREDICTED: maternal em ( 619) 407 52.8 2.5e-06
XP_011516383 (OMIM: 607025) PREDICTED: maternal em ( 619) 407 52.8 2.5e-06
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622) 407 52.8 2.5e-06
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 407 52.8 2.6e-06
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 407 52.8 2.6e-06
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651) 407 52.8 2.6e-06
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651) 407 52.8 2.6e-06
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651) 407 52.8 2.6e-06
XP_011541028 (OMIM: 614776) PREDICTED: serine/thre ( 660) 402 52.4 3.6e-06
XP_005259384 (OMIM: 609235) PREDICTED: serine/thre ( 688) 402 52.4 3.7e-06
XP_005267700 (OMIM: 602678) PREDICTED: MAP/microtu ( 643) 400 52.2 4.1e-06
NP_742081 (OMIM: 607707) calcium/calmodulin-depend ( 449) 396 51.6 4.2e-06
XP_016876782 (OMIM: 602678) PREDICTED: MAP/microtu ( 708) 400 52.2 4.3e-06
NP_001122392 (OMIM: 602678) MAP/microtubule affini ( 713) 400 52.2 4.3e-06
XP_016876781 (OMIM: 602678) PREDICTED: MAP/microtu ( 722) 400 52.2 4.4e-06
XP_016876780 (OMIM: 602678) PREDICTED: MAP/microtu ( 728) 400 52.2 4.4e-06
NP_002367 (OMIM: 602678) MAP/microtubule affinity- ( 729) 400 52.2 4.4e-06
NP_742080 (OMIM: 607707) calcium/calmodulin-depend ( 479) 396 51.6 4.4e-06
XP_005267699 (OMIM: 602678) PREDICTED: MAP/microtu ( 737) 400 52.2 4.4e-06
XP_005267698 (OMIM: 602678) PREDICTED: MAP/microtu ( 738) 400 52.2 4.4e-06
XP_006720209 (OMIM: 602678) PREDICTED: MAP/microtu ( 739) 400 52.2 4.4e-06
NP_001122391 (OMIM: 602678) MAP/microtubule affini ( 744) 400 52.2 4.4e-06
NP_001122390 (OMIM: 602678) MAP/microtubule affini ( 753) 400 52.2 4.5e-06
NP_742079 (OMIM: 607707) calcium/calmodulin-depend ( 492) 396 51.6 4.5e-06
XP_016868154 (OMIM: 607707) PREDICTED: calcium/cal ( 493) 396 51.6 4.5e-06
XP_005249921 (OMIM: 607707) PREDICTED: calcium/cal ( 494) 396 51.6 4.5e-06
XP_016868153 (OMIM: 607707) PREDICTED: calcium/cal ( 502) 396 51.6 4.5e-06
>>NP_079471 (OMIM: 609461) tribbles homolog 1 isoform 1 (372 aa)
initn: 2529 init1: 2529 opt: 2529 Z-score: 1341.3 bits: 256.8 E(85289): 5.7e-68
Smith-Waterman score: 2529; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 SPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 VFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 EAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 DKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 FCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_079 FCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE
310 320 330 340 350 360
370
pF1KB5 YQEDSDISSFFC
::::::::::::
NP_079 YQEDSDISSFFC
370
>>NP_001269914 (OMIM: 609461) tribbles homolog 1 isoform (206 aa)
initn: 1378 init1: 1378 opt: 1378 Z-score: 745.3 bits: 145.7 E(85289): 9e-35
Smith-Waterman score: 1378; 100.0% identity (100.0% similar) in 206 aa overlap (167-372:1-206)
140 150 160 170 180 190
pF1KB5 LPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHC
::::::::::::::::::::::::::::::
NP_001 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
200 210 220 230 240 250
pF1KB5 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB5 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB5 SLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
160 170 180 190 200
>>NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo sapi (343 aa)
initn: 1283 init1: 1215 opt: 1266 Z-score: 684.5 bits: 135.2 E(85289): 2.2e-31
Smith-Waterman score: 1275; 61.9% identity (81.2% similar) in 320 aa overlap (56-371:35-342)
30 40 50 60 70 80
pF1KB5 TRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPP-GSPCSPQPPPAAPGAGGGSGS
: . .:: ::: :. : . .
NP_067 RSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCV------
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 APGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNIT
: :. :::: : .:: ::. .:.:.:: :::: :. ::... : . : .::::.
NP_067 ----SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNIN
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB5 GIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLG
:.:.::::::::::::...:::::.::. :.:::::::::: ::.:::::::....::
NP_067 QITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLR
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB5 DLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKA
:::::::.:. ::::...::::::..:..:.::.::::::::::::::::::.:.:::::
NP_067 DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKA
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB5 ADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPS
::::::::::::.::::::::: .::.:::::::::: ::: .::::.:::::.::::::
NP_067 ADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPS
240 250 260 270 280 290
330 340 350 360 370
pF1KB5 ERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
::::. ::: :::: :: . .: .:. :::.::. . . ... ::
NP_067 ERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
300 310 320 330 340
>>XP_016883478 (OMIM: 607898) PREDICTED: tribbles homolo (385 aa)
initn: 1019 init1: 928 opt: 992 Z-score: 541.4 bits: 108.9 E(85289): 2e-23
Smith-Waterman score: 992; 46.6% identity (70.1% similar) in 348 aa overlap (15-360:27-365)
10 20 30 40
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCP
: :. : :: .. :. :. :: . .. :
XP_016 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAG-SLSRKKRLELDDN--LDTERP
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RLSECSSPPDYLSPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSR
.. : :. : :: : ::.:: . . ..: ::.. :.:: : .. .
XP_016 VQKRARSGPQ---PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 ALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDM
:: :: : :::.:... ..:: .:: :.... .::. : :.:: . :::
XP_016 ALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 HSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLE
:: ::::.:. : ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.::
XP_016 HSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDS
:. .. : ::.: :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::
XP_016 DSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 DPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GY
.: ::.::::: . .: .: ::::.: ::::::.::::: ::::::... : .
XP_016 EPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAP
300 310 320 330 340 350
350 360 370
pF1KB5 IDSEIGTSDQIVPEYQEDSDISSFFC
:.. . :.::.
XP_016 TRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
360 370 380
>>NP_001288130 (OMIM: 607898) tribbles homolog 3 isoform (385 aa)
initn: 1019 init1: 928 opt: 992 Z-score: 541.4 bits: 108.9 E(85289): 2e-23
Smith-Waterman score: 992; 46.6% identity (70.1% similar) in 348 aa overlap (15-360:27-365)
10 20 30 40
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCP
: :. : :: .. :. :. :: . .. :
NP_001 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAG-SLSRKKRLELDDN--LDTERP
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RLSECSSPPDYLSPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSR
.. : :. : :: : ::.:: . . ..: ::.. :.:: : .. .
NP_001 VQKRARSGPQ---PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 ALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDM
:: :: : :::.:... ..:: .:: :.... .::. : :.:: . :::
NP_001 ALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 HSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLE
:: ::::.:. : ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.::
NP_001 HSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDS
:. .. : ::.: :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::
NP_001 DSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 DPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GY
.: ::.::::: . .: .: ::::.: ::::::.::::: ::::::... : .
NP_001 EPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAP
300 310 320 330 340 350
350 360 370
pF1KB5 IDSEIGTSDQIVPEYQEDSDISSFFC
:.. . :.::.
NP_001 TRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
360 370 380
>>NP_001288122 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 1019 init1: 928 opt: 988 Z-score: 539.6 bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
:. : :: .. :. :. :: . .. : .. : :.
NP_001 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
10 20 30 40
70 80 90 100 110
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
280 290 300 310 320 330
360 370
pF1KB5 PEYQEDSDISSFFC
:.
NP_001 PDGLGLDEAREEEGDREVVLYG
340 350
>>NP_001288125 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 1019 init1: 928 opt: 988 Z-score: 539.6 bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
:. : :: .. :. :. :: . .. : .. : :.
NP_001 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
10 20 30 40
70 80 90 100 110
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
280 290 300 310 320 330
360 370
pF1KB5 PEYQEDSDISSFFC
:.
NP_001 PDGLGLDEAREEEGDREVVLYG
340 350
>>NP_001288119 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 1019 init1: 928 opt: 988 Z-score: 539.6 bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
:. : :: .. :. :. :: . .. : .. : :.
NP_001 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
10 20 30 40
70 80 90 100 110
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
280 290 300 310 320 330
360 370
pF1KB5 PEYQEDSDISSFFC
:.
NP_001 PDGLGLDEAREEEGDREVVLYG
340 350
>>NP_001288117 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 1019 init1: 928 opt: 988 Z-score: 539.6 bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
:. : :: .. :. :. :: . .. : .. : :.
NP_001 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
10 20 30 40
70 80 90 100 110
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
NP_001 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
NP_001 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_001 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
NP_001 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
NP_001 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
280 290 300 310 320 330
360 370
pF1KB5 PEYQEDSDISSFFC
:.
NP_001 PDGLGLDEAREEEGDREVVLYG
340 350
>>NP_066981 (OMIM: 607898) tribbles homolog 3 isoform 1 (358 aa)
initn: 1019 init1: 928 opt: 988 Z-score: 539.6 bits: 108.5 E(85289): 2.6e-23
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
:. : :: .. :. :. :: . .. : .. : :.
NP_066 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
10 20 30 40
70 80 90 100 110
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
NP_066 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
NP_066 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_066 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
NP_066 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
NP_066 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
280 290 300 310 320 330
360 370
pF1KB5 PEYQEDSDISSFFC
:.
NP_066 PDGLGLDEAREEEGDREVVLYG
340 350
372 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:53:43 2016 done: Thu Nov 3 17:53:45 2016
Total Scan time: 9.250 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]