Result of FASTA (ccds) for
pFN21AB5662
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5662, 372 aa
1>>>pF1KB5662 372 - 372 aa - 372 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 10.0339+/-0.000917; mu= -2.5026+/- 0.055
mean_var=304.9786+/-64.924, 0's: 0 Z-trim(116.1): 302 B-trim: 3 in 1/53
Lambda= 0.073441
statistics sampled from 16351 (16690) to 16351 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.805), E-opt: 0.2 (0.513), width: 16
Scan time: 2.850
The best scores are: opt bits E(32554)
CCDS6357.1 TRIB1 gene_id:10221|Hs108|chr8 ( 372) 2529 280.8 1.3e-75
CCDS64971.1 TRIB1 gene_id:10221|Hs108|chr8 ( 206) 1378 158.6 4.4e-39
CCDS1683.1 TRIB2 gene_id:28951|Hs108|chr2 ( 343) 1266 147.0 2.4e-35
CCDS77554.1 TRIB3 gene_id:57761|Hs108|chr20 ( 385) 992 118.0 1.4e-26
CCDS12997.1 TRIB3 gene_id:57761|Hs108|chr20 ( 358) 988 117.5 1.8e-26
>>CCDS6357.1 TRIB1 gene_id:10221|Hs108|chr8 (372 aa)
initn: 2529 init1: 2529 opt: 2529 Z-score: 1470.8 bits: 280.8 E(32554): 1.3e-75
Smith-Waterman score: 2529; 100.0% identity (100.0% similar) in 372 aa overlap (1-372:1-372)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 SPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 SPPGSPCSPQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRCK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 VFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 VFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 EAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 EAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 DKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 DKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB5 FCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS63 FCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPE
310 320 330 340 350 360
370
pF1KB5 YQEDSDISSFFC
::::::::::::
CCDS63 YQEDSDISSFFC
370
>>CCDS64971.1 TRIB1 gene_id:10221|Hs108|chr8 (206 aa)
initn: 1378 init1: 1378 opt: 1378 Z-score: 815.1 bits: 158.6 E(32554): 4.4e-39
Smith-Waterman score: 1378; 100.0% identity (100.0% similar) in 206 aa overlap (167-372:1-206)
140 150 160 170 180 190
pF1KB5 LPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHC
::::::::::::::::::::::::::::::
CCDS64 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
200 210 220 230 240 250
pF1KB5 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
260 270 280 290 300 310
pF1KB5 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
100 110 120 130 140 150
320 330 340 350 360 370
pF1KB5 SLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 SLLRREPSERLTAPEILLHPWFESVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
160 170 180 190 200
>>CCDS1683.1 TRIB2 gene_id:28951|Hs108|chr2 (343 aa)
initn: 1283 init1: 1215 opt: 1266 Z-score: 748.0 bits: 147.0 E(32554): 2.4e-35
Smith-Waterman score: 1275; 61.9% identity (81.2% similar) in 320 aa overlap (56-371:35-342)
30 40 50 60 70 80
pF1KB5 TRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYLSPP-GSPCSPQPPPAAPGAGGGSGS
: . .:: ::: :. : . .
CCDS16 RSTPITIARYGRSRNKTQDFEELSSIRSAEPSQSFSPNLGSPSPPETPNLSHCV------
10 20 30 40 50
90 100 110 120 130 140
pF1KB5 APGPSRIADYLLLPLAEREHVSRALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNIT
: :. :::: : .:: ::. .:.:.:: :::: :. ::... : . : .::::.
CCDS16 ----SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAHSNIN
60 70 80 90 100 110
150 160 170 180 190 200
pF1KB5 GIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLG
:.:.::::::::::::...:::::.::. :.:::::::::: ::.:::::::....::
CCDS16 QITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGGLVLR
120 130 140 150 160 170
210 220 230 240 250 260
pF1KB5 DLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKA
:::::::.:. ::::...::::::..:..:.::.::::::::::::::::::.:.:::::
CCDS16 DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSYSGKA
180 190 200 210 220 230
270 280 290 300 310 320
pF1KB5 ADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPS
::::::::::::.::::::::: .::.:::::::::: ::: .::::.:::::.::::::
CCDS16 ADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILRREPS
240 250 260 270 280 290
330 340 350 360 370
pF1KB5 ERLTAPEILLHPWFE---SVLEPGYIDSEIGTSDQIVPEYQEDSDISSFFC
::::. ::: :::: :: . .: .:. :::.::. . . ... ::
CCDS16 ERLTSQEILDHPWFSTDFSVSNSAYGAKEV--SDQLVPDVNMEENLDPFFN
300 310 320 330 340
>>CCDS77554.1 TRIB3 gene_id:57761|Hs108|chr20 (385 aa)
initn: 1019 init1: 928 opt: 992 Z-score: 590.5 bits: 118.0 E(32554): 1.4e-26
Smith-Waterman score: 992; 46.6% identity (70.1% similar) in 348 aa overlap (15-360:27-365)
10 20 30 40
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCP
: :. : :: .. :. :. :: . .. :
CCDS77 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAG-SLSRKKRLELDDN--LDTERP
10 20 30 40 50
50 60 70 80 90 100
pF1KB5 RLSECSSPPDYLSPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSR
.. : :. : :: : ::.:: . . ..: ::.. :.:: : .. .
CCDS77 VQKRARSGPQ---PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQ
60 70 80 90 100 110
110 120 130 140 150 160
pF1KB5 ALCIHTGRELRCKVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDM
:: :: : :::.:... ..:: .:: :.... .::. : :.:: . :::
CCDS77 ALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDM
120 130 140 150 160 170
170 180 190 200 210 220
pF1KB5 HSYVRSRKRLREEEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLE
:: ::::.:. : ::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.::
CCDS77 HSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KB5 DTHIMKGEDDALSDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDS
:. .. : ::.: :::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::
CCDS77 DSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDS
240 250 260 270 280 290
290 300 310 320 330 340
pF1KB5 DPSALFSKIRRGQFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GY
.: ::.::::: . .: .: ::::.: ::::::.::::: ::::::... : .
CCDS77 EPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAP
300 310 320 330 340 350
350 360 370
pF1KB5 IDSEIGTSDQIVPEYQEDSDISSFFC
:.. . :.::.
CCDS77 TRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
360 370 380
>>CCDS12997.1 TRIB3 gene_id:57761|Hs108|chr20 (358 aa)
initn: 1019 init1: 928 opt: 988 Z-score: 588.6 bits: 117.5 E(32554): 1.8e-26
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (17-360:2-338)
10 20 30 40 50 60
pF1KB5 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
:. : :: .. :. :. :: . .. : .. : :.
CCDS12 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
10 20 30 40
70 80 90 100 110
pF1KB5 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
CCDS12 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
50 60 70 80 90
120 130 140 150 160 170
pF1KB5 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
CCDS12 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
100 110 120 130 140 150
180 190 200 210 220 230
pF1KB5 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
CCDS12 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KB5 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
CCDS12 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
220 230 240 250 260 270
300 310 320 330 340 350
pF1KB5 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
CCDS12 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
280 290 300 310 320 330
360 370
pF1KB5 PEYQEDSDISSFFC
:.
CCDS12 PDGLGLDEAREEEGDREVVLYG
340 350
372 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 17:53:42 2016 done: Thu Nov 3 17:53:43 2016
Total Scan time: 2.850 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]