Result of FASTA (omim) for
pFN21AB5017
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB5017, 338 aa
1>>>pF1KB5017 338 - 338 aa - 338 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1257+/-0.000298; mu= 3.9182+/- 0.019
mean_var=168.1439+/-35.137, 0's: 0 Z-trim(121.8): 19 B-trim: 2154 in 1/53
Lambda= 0.098909
statistics sampled from 38885 (38904) to 38885 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.786), E-opt: 0.2 (0.456), width: 16
Scan time: 7.360
The best scores are: opt bits E(85289)
NP_001231627 (OMIM: 601064) zinc finger protein 36 ( 338) 2302 339.9 4.5e-93
NP_004917 (OMIM: 601064) zinc finger protein 36, C ( 338) 2302 339.9 4.5e-93
NP_001231630 (OMIM: 601064) zinc finger protein 36 ( 407) 2302 340.0 5.3e-93
NP_008818 (OMIM: 612053) zinc finger protein 36, C ( 494) 674 107.7 5.3e-23
NP_003398 (OMIM: 190700) tristetraprolin [Homo sap ( 332) 509 84.1 4.7e-16
>>NP_001231627 (OMIM: 601064) zinc finger protein 36, C3 (338 aa)
initn: 2302 init1: 2302 opt: 2302 Z-score: 1791.9 bits: 339.9 E(85289): 4.5e-93
Smith-Waterman score: 2302; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338)
10 20 30 40 50 60
pF1KB5 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLS
250 260 270 280 290 300
310 320 330
pF1KB5 DQEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD
::::::::::::::::::::::::::::::::::::::
NP_001 DQEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD
310 320 330
>>NP_004917 (OMIM: 601064) zinc finger protein 36, C3H1 (338 aa)
initn: 2302 init1: 2302 opt: 2302 Z-score: 1791.9 bits: 339.9 E(85289): 4.5e-93
Smith-Waterman score: 2302; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:1-338)
10 20 30 40 50 60
pF1KB5 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGGGFPRRHSVTLPSS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB5 KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KFHQNQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELC
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB5 RPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 RPFEENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB5 ERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 ERRALAGARDLSADRPRLQHSFSFAGFPSAAATAAATGLLDSPTSITPPPILSADDLLGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB5 PTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSPQDSLS
250 260 270 280 290 300
310 320 330
pF1KB5 DQEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD
::::::::::::::::::::::::::::::::::::::
NP_004 DQEGYLSSSSSSHSGSDSPTLDNSRRLPIFSRLSISDD
310 320 330
>>NP_001231630 (OMIM: 601064) zinc finger protein 36, C3 (407 aa)
initn: 2302 init1: 2302 opt: 2302 Z-score: 1790.7 bits: 340.0 E(85289): 5.3e-93
Smith-Waterman score: 2302; 100.0% identity (100.0% similar) in 338 aa overlap (1-338:70-407)
10 20 30
pF1KB5 MTTTLVSATIFDLSEVLCKGNKMLNYSAPS
::::::::::::::::::::::::::::::
NP_001 GLQTGEAAPSPHRDLRDTPDPRPWLARTHRMTTTLVSATIFDLSEVLCKGNKMLNYSAPS
40 50 60 70 80 90
40 50 60 70 80 90
pF1KB5 AGGCLLDRKAVGTPAGGGFPRRHSVTLPSSKFHQNQLLSSLKGEPAPALSSRDSRFRDRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGGCLLDRKAVGTPAGGGFPRRHSVTLPSSKFHQNQLLSSLKGEPAPALSSRDSRFRDRS
100 110 120 130 140 150
100 110 120 130 140 150
pF1KB5 FSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFEENGACKYGDKCQFAHGIHELRSLTRH
160 170 180 190 200 210
160 170 180 190 200 210
pF1KB5 PKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRALAGARDLSADRPRLQHSFSFAGFPSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRALAGARDLSADRPRLQHSFSFAGFPSA
220 230 240 250 260 270
220 230 240 250 260 270
pF1KB5 AATAAATGLLDSPTSITPPPILSADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AATAAATGLLDSPTSITPPPILSADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPG
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB5 GGSPTTFLFRPMSESPHMFDSPPSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNSRRLPIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGSPTTFLFRPMSESPHMFDSPPSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNSRRLPIF
340 350 360 370 380 390
pF1KB5 SRLSISDD
::::::::
NP_001 SRLSISDD
400
>>NP_008818 (OMIM: 612053) zinc finger protein 36, C3H1 (494 aa)
initn: 941 init1: 552 opt: 674 Z-score: 534.0 bits: 107.7 E(85289): 5.3e-23
Smith-Waterman score: 737; 49.8% identity (64.2% similar) in 285 aa overlap (11-230:10-290)
10 20 30 40 50
pF1KB5 MTTTLVSATIFDLSEVLCKGNKMLNYSAPSAGGCLLDRKAVGTPAGG--------GFPRR
.:. . ::: .: : : . .::.::::::... :: ::
NP_008 MSTTLLSAFYDV-DFLCKTEKSL---ANLNLNNMLDKKAVGTPVAAAPSSGFAPGFLRR
10 20 30 40 50
60 70 80
pF1KB5 HSVT--------LPSS-----KF----HQNQLLSSLKGEPA-------P------ALSSR
::.. :: :: . .. :. : :. : :: ..
NP_008 HSASNLHALAHPAPSPGSCSPKFPGAANGSSCGSAAAGGPTSYGTLKEPSGGGGTALLNK
60 70 80 90 100 110
90 100 110 120 130
pF1KB5 DSRFRDRSFSEGGER---LLPTQKQP---GGGQVNSSRYKTELCRPFEENGACKYGDKCQ
...::::::::.:.: :: :.: ::.:.::.::::::::::::.:.::::.:::
NP_008 ENKFRDRSFSENGDRSQHLLHLQQQQKGGGGSQINSTRYKTELCRPFEESGTCKYGEKCQ
120 130 140 150 160 170
140 150 160 170 180 190
pF1KB5 FAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRAL--AGAR-DLSA
::::.::::::::::::::::::::::::::::::::::::::.::: .:: :: :
NP_008 FAHGFHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNADERRPAPSGGASGDLRA
180 190 200 210 220 230
200 210 220 230
pF1KB5 --------------DRPRLQHSFSFAGFPSA----AATAAATGLLDSPTSITPPPILSAD
::.:.::.::.::::. . . ::::::: ::::
NP_008 FGTRDALHLGFPREPRPKLHHSLSFSGFPSGHHQPPGGLESPLLLDSPTSRTPPPPSCSS
240 250 260 270 280 290
240 250 260 270 280 290
pF1KB5 DLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSPPSP
NP_008 ASSCSSSASSCSSASAASTPSGAPTCCASAAAAAAAALLYGTGGAEDLLAPGAPCAACSS
300 310 320 330 340 350
>--
initn: 240 init1: 152 opt: 280 Z-score: 230.2 bits: 51.5 E(85289): 4.4e-06
Smith-Waterman score: 280; 60.2% identity (79.5% similar) in 83 aa overlap (264-338:413-494)
240 250 260 270 280
pF1KB5 ADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGS-----PTTF-LFRPMSESPH
:: ::.:.. : .: : : .:.::
NP_008 FAAVAAAAYYRSQQQQQQQGLAPPAQPPAPPSATLPAGAAAPPSPPFSFQLPRRLSDSP-
390 400 410 420 430 440
290 300 310 320 330
pF1KB5 MFDSPPSPQDSLSDQEGYLSSS--SSSHSGSDSPTLDNSRRLPIFSRLSISDD
.::.:::: :::::...:::.: :.: :::.::.:: .::::::::::::::
NP_008 VFDAPPSPPDSLSDRDSYLSGSLSSGSLSGSESPSLDPGRRLPIFSRLSISDD
450 460 470 480 490
>>NP_003398 (OMIM: 190700) tristetraprolin [Homo sapiens (332 aa)
initn: 494 init1: 377 opt: 509 Z-score: 409.3 bits: 84.1 E(85289): 4.7e-16
Smith-Waterman score: 530; 40.2% identity (56.0% similar) in 266 aa overlap (95-337:90-332)
70 80 90 100 110 120
pF1KB5 NQLLSSLKGEPAPALSSRDSRFRDRSFSEGGERLLPTQKQPGGGQVNSSRYKTELCRPFE
: .: :. .: . ... ::::::::: :
NP_003 LPGRSTSLVEGRSCGWVPPPPGFAPLAPRLGPELSPSPTSPTATSTTPSRYKTELCRTFS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB5 ENGACKYGDKCQFAHGIHELRSLTRHPKYKTELCRTFHTIGFCPYGPRCHFIHNAEERRA
:.: :.:: :::::::. :::. .::::::::::. :. : :::: ::::::: : :
NP_003 ESGRCRYGAKCQFAHGLGELRQANRHPKYKTELCHKFYLQGRCPYGSRCHFIHNPSEDLA
120 130 140 150 160 170
190 200 210 220 230
pF1KB5 LAGARDLSADRPRLQHSFSFAGFPSAAATAAAT-GLLD--------SPTSITPPP---IL
: : :..:.::.:.::. :. :: ::.: ::: :
NP_003 APG------HPPVLRQSISFSGLPSGRRTSPPPPGLAGPSLSSSSFSPSSSPPPPGDLPL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB5 SADDLLGSPTLPDGTNNPFAFSSQELASLFAPSMGLPGGGSPTTFLFRPMSESPHMFDSP
: . . ..: : . .: :. : :: : :
NP_003 SPSAFSAAPGTPLARRDPTPVCCPSCRRATPISVWGPLGG-----LVRT-----------
240 250 260 270
300 310 320 330
pF1KB5 PSPQDSLSDQEGYLSSSSSSHSGSDSPTLDNS-----------RRLPIFSRLSISDD
:: :. :: . : .::.:: .:::::... . ::::::.:.:.:.
NP_003 PSVQSLGSDPDEY-ASSGSSLGGSDSPVFEAGVFAPPQPVAAPRRLPIFNRISVSE
280 290 300 310 320 330
338 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 15:46:35 2016 done: Thu Nov 3 15:46:36 2016
Total Scan time: 7.360 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]