Result of FASTA (omim) for
pFN21AB3475
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3475, 492 aa
1>>>pF1KB3475 492 - 492 aa - 492 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0399+/-0.000443; mu= 19.5021+/- 0.027
mean_var=69.5925+/-15.097, 0's: 0 Z-trim(110.3): 202 B-trim: 1002 in 1/47
Lambda= 0.153742
statistics sampled from 18453 (18675) to 18453 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.219), width: 16
Scan time: 7.250
The best scores are: opt bits E(85289)
NP_006507 (OMIM: 138140,143090,608885) solute carr ( 492) 3206 720.8 2.2e-207
NP_001033 (OMIM: 138190) solute carrier family 2, ( 509) 2133 482.8 1e-135
NP_008862 (OMIM: 138170) solute carrier family 2, ( 496) 2121 480.1 6.2e-135
NP_703150 (OMIM: 611039) solute carrier family 2, ( 520) 2064 467.5 4.1e-131
NP_001273162 (OMIM: 611039) solute carrier family ( 520) 2064 467.5 4.1e-131
XP_016874334 (OMIM: 611039) PREDICTED: solute carr ( 521) 2055 465.5 1.6e-130
XP_016874332 (OMIM: 611039) PREDICTED: solute carr ( 521) 2055 465.5 1.6e-130
XP_016874331 (OMIM: 611039) PREDICTED: solute carr ( 521) 2055 465.5 1.6e-130
XP_016874330 (OMIM: 611039) PREDICTED: solute carr ( 521) 2055 465.5 1.6e-130
XP_016874333 (OMIM: 611039) PREDICTED: solute carr ( 521) 2055 465.5 1.6e-130
NP_001273164 (OMIM: 611039) solute carrier family ( 497) 2051 464.6 2.9e-130
XP_016874336 (OMIM: 611039) PREDICTED: solute carr ( 497) 2051 464.6 2.9e-130
XP_005253374 (OMIM: 611039) PREDICTED: solute carr ( 497) 2051 464.6 2.9e-130
XP_016874335 (OMIM: 611039) PREDICTED: solute carr ( 497) 2051 464.6 2.9e-130
XP_011518864 (OMIM: 611039) PREDICTED: solute carr ( 497) 2051 464.6 2.9e-130
XP_011518865 (OMIM: 611039) PREDICTED: solute carr ( 497) 2051 464.6 2.9e-130
XP_005253372 (OMIM: 611039) PREDICTED: solute carr ( 497) 2051 464.6 2.9e-130
NP_001273163 (OMIM: 611039) solute carrier family ( 497) 2051 464.6 2.9e-130
NP_001273166 (OMIM: 611039) solute carrier family ( 535) 2051 464.6 3.1e-130
XP_011511389 (OMIM: 125853,138160,227810) PREDICTE ( 509) 1736 394.7 3.2e-109
NP_000331 (OMIM: 125853,138160,227810) solute carr ( 524) 1736 394.7 3.3e-109
XP_011518866 (OMIM: 611039) PREDICTED: solute carr ( 411) 1713 389.5 9.4e-108
XP_011518867 (OMIM: 611039) PREDICTED: solute carr ( 411) 1713 389.5 9.4e-108
NP_001273165 (OMIM: 611039) solute carrier family ( 411) 1713 389.5 9.4e-108
NP_001265587 (OMIM: 125853,138160,227810) solute c ( 405) 1637 372.7 1.1e-102
XP_011511391 (OMIM: 125853,138160,227810) PREDICTE ( 351) 1452 331.6 2.2e-90
NP_001265588 (OMIM: 125853,138160,227810) solute c ( 351) 1452 331.6 2.2e-90
NP_001315548 (OMIM: 138230) solute carrier family ( 501) 1340 306.9 8.8e-83
XP_016857630 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_016857624 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_005263548 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_016857627 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_016857626 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_016857623 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_016857622 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
XP_016857629 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
NP_003030 (OMIM: 138230) solute carrier family 2, ( 501) 1340 306.9 8.8e-83
XP_016857625 (OMIM: 138230) PREDICTED: solute carr ( 501) 1340 306.9 8.8e-83
NP_997303 (OMIM: 610371) solute carrier family 2, ( 512) 1296 297.1 7.7e-80
XP_011512162 (OMIM: 606142,612076) PREDICTED: solu ( 537) 1258 288.7 2.8e-77
NP_001001290 (OMIM: 606142,612076) solute carrier ( 511) 1256 288.3 3.6e-77
NP_064425 (OMIM: 606142,612076) solute carrier fam ( 540) 1256 288.3 3.8e-77
XP_011512161 (OMIM: 606142,612076) PREDICTED: solu ( 538) 1253 287.6 6e-77
XP_006714031 (OMIM: 606142,612076) PREDICTED: solu ( 563) 1253 287.6 6.2e-77
XP_016863946 (OMIM: 606142,612076) PREDICTED: solu ( 609) 1253 287.6 6.6e-77
NP_001315549 (OMIM: 138230) solute carrier family ( 457) 1232 282.9 1.3e-75
XP_011539126 (OMIM: 610371) PREDICTED: solute carr ( 517) 1183 272.1 2.7e-72
XP_016863947 (OMIM: 606142,612076) PREDICTED: solu ( 487) 1171 269.4 1.7e-71
XP_011512163 (OMIM: 606142,612076) PREDICTED: solu ( 486) 1157 266.3 1.4e-70
XP_011512160 (OMIM: 606142,612076) PREDICTED: solu ( 586) 1156 266.1 1.9e-70
>>NP_006507 (OMIM: 138140,143090,608885) solute carrier (492 aa)
initn: 3206 init1: 3206 opt: 3206 Z-score: 3844.1 bits: 720.8 E(85289): 2.2e-207
Smith-Waterman score: 3206; 100.0% identity (100.0% similar) in 492 aa overlap (1-492:1-492)
10 20 30 40 50 60
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB3 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB3 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB3 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB3 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KB3 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
370 380 390 400 410 420
430 440 450 460 470 480
pF1KB3 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
430 440 450 460 470 480
490
pF1KB3 ELFHPLGADSQV
::::::::::::
NP_006 ELFHPLGADSQV
490
>>NP_001033 (OMIM: 138190) solute carrier family 2, faci (509 aa)
initn: 2129 init1: 1905 opt: 2133 Z-score: 2557.7 bits: 482.8 E(85289): 1e-135
Smith-Waterman score: 2133; 65.5% identity (86.8% similar) in 493 aa overlap (2-489:14-506)
10 20 30 40
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTW
:: ....:: :.::: .::::::::::: :::::::::::. ::.::
NP_001 MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETW
10 20 30 40 50 60
50 60 70 80 90 100
pF1KB3 VHRYGE----SILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAF
. : : :: : ::::::.::::::::::::.:: .:.. . .::. .::. :.::
NP_001 LGRQGPEGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAV
70 80 90 100 110 120
110 120 130 140 150 160
pF1KB3 VSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGI
... :::... . :.::::::::.::.: :::.:.:::::::..:: ::::::::.::.:
NP_001 LGGSLMGLANAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAI
130 140 150 160 170 180
170 180 190 200 210 220
pF1KB3 VVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRA
:.:::::::.::.:..:. .::::::.. .::::: ..:::::::::.: : .: :. :
NP_001 VIGILIAQVLGLESLLGTASLWPLLLGLTVLPALLQLVLLPFCPESPRYLYIIQNLEGPA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KB3 KSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQL
.. ::.: : :::. : :.:.:.:.. ::. ...:.:. : ..:::..:::::::::::
NP_001 RKSLKRLTGWADVSGVLAELKDEKRKLERERPLSLLQLLGSRTHRQPLIIAVVLQLSQQL
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB3 SGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGM
::::::::::::::: ::: ::.:::::.:.:::.::.::...:::::::::::.:::::
NP_001 SGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVLLVERAGRRTLHLLGLAGM
310 320 330 340 350 360
350 360 370 380 390 400
pF1KB3 AGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAI
:::::::.:: :::..: :::.:::::::::::::.::::::::::::::::::::::.
NP_001 CGCAILMTVALLLLERVPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAM
370 380 390 400 410 420
410 420 430 440 450 460
pF1KB3 AVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIA
:::::::::::::.:: :::: . :::::..:.:::. :::::...::::.:::::.:.
NP_001 AVAGFSNWTSNFIIGMGFQYVAEAMGPYVFLLFAVLLLGFFIFTFLRVPETRGRTFDQIS
430 440 450 460 470 480
470 480 490
pF1KB3 SGF-RQGGASQSDKTPEELFHPLGADSQV
..: : . ... : .. :: :
NP_001 AAFHRTPSLLEQEVKPSTELEYLGPDEND
490 500
>>NP_008862 (OMIM: 138170) solute carrier family 2, faci (496 aa)
initn: 2101 init1: 2078 opt: 2121 Z-score: 2543.5 bits: 480.1 E(85289): 6.2e-135
Smith-Waterman score: 2121; 65.8% identity (87.6% similar) in 477 aa overlap (5-481:3-478)
10 20 30 40 50 60
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQKVIEEFYNQTWVHRYGESILPTT
..:.: :..:. :..::.::::::::::::.:.:.:: :.: . . . .
NP_008 MGTQKVTPALIFAITVATIGSFQFGYNTGVINAPEKIIKEFINKTLTDKGNAPPSEVL
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 LTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLMMNLLAFVSAVLMGFSKLGKSFE
::.::::::::::::::::::::::::::::::::::..:::: ... .::. :..:: :
NP_008 LTSLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLIVNLLAVTGGCFMGLCKVAKSVE
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB3 MLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGTLHQLGIVVGILIAQVFGLDSIM
::::::..::..::: :::::::.::.::::::::.:::.:::::::::.::.:::. :.
NP_008 MLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGTLNQLGIVVGILVAQIFGLEFIL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB3 GNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINRNEENRAKSVLKKLRGTADVTHD
:...::::::.. ..::.:: .:::::::::::::::.::. ::..:..: :: ::..:
NP_008 GSEELWPLLLGFTILPAILQSAALPFCPESPRFLLINRKEEENAKQILQRLWGTQDVSQD
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB3 LQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVLQLSQQLSGINAVFYYSTSIFEK
.::::.:: .: .::.::.::::: .:::::.:..:::::::::::::::::::.::.
NP_008 IQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVLQLSQQLSGINAVFYYSTGIFKD
240 250 260 270 280 290
310 320 330 340 350 360
pF1KB3 AGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHLIGLAGMAGCAILMTIALALLEQ
::::.:.:::::.:.::: :::::::.::::::::::.:::.::: :. :::..: : ..
NP_008 AGVQEPIYATIGAGVVNTIFTVVSLFLVERAGRRTLHMIGLGGMAFCSTLMTVSLLLKDN
300 310 320 330 340 350
370 380 390 400 410 420
pF1KB3 LPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQGPRPAAIAVAGFSNWTSNFIVGM
::.. : ::. ::::::.::::::::::::::::::::::.:::: :::::::.::.
NP_008 YNGMSFVCIGAILVFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGCSNWTSNFLVGL
360 370 380 390 400 410
430 440 450 460 470 480
pF1KB3 CFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGRTFDEIASGFRQGGASQSDKTPE
: . . : ::::::: .:. :. ::.::::::.::::..:. .: .: : .:.. .
NP_008 LFPSAAHYLGAYVFIIFTGFLITFLAFTFFKVPETRGRTFEDITRAF-EGQAHGADRSGK
420 430 440 450 460 470
490
pF1KB3 ELFHPLGADSQV
.
NP_008 DGVMEMNSIEPAKETTTNV
480 490
>>NP_703150 (OMIM: 611039) solute carrier family 2, faci (520 aa)
initn: 2016 init1: 2016 opt: 2064 Z-score: 2474.8 bits: 467.5 E(85289): 4.1e-131
Smith-Waterman score: 2064; 63.6% identity (85.9% similar) in 481 aa overlap (1-481:23-502)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQK
:.: . .: :..:. :..::.::::::::::::.
NP_703 MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPET
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 VIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLM
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::.
NP_703 IIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGT
.:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.::
NP_703 VNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGT
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 LHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINR
:.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: ::::::::::::
NP_703 LNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 NEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVL
..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..::
NP_703 KKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 QLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHL
:::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::.
NP_703 QLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHM
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 IGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQG
:::.::: :. :::..: : .. ::.. : ::. ::: ::.:::::::::::::::::
NP_703 IGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 PRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGR
:::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.::
NP_703 PRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGR
430 440 450 460 470 480
460 470 480 490
pF1KB3 TFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
::..:. .: .: : .:.. ..
NP_703 TFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
>>NP_001273162 (OMIM: 611039) solute carrier family 2, f (520 aa)
initn: 2016 init1: 2016 opt: 2064 Z-score: 2474.8 bits: 467.5 E(85289): 4.1e-131
Smith-Waterman score: 2064; 63.6% identity (85.9% similar) in 481 aa overlap (1-481:23-502)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQK
:.: . .: :..:. :..::.::::::::::::.
NP_001 MEFHNGGHVSGIGGFLVSLTSRMKPHTLAVTPALIFAITVATIGSFQFGYNTGVINAPET
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 VIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLM
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::.
NP_001 IIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSMLI
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALGT
.:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.::
NP_001 VNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFGT
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 LHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLINR
:.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: ::::::::::::
NP_001 LNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLINR
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 NEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVVL
..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..::
NP_001 KKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIVL
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 QLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLHL
:::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::.
NP_001 QLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLHM
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 IGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQG
:::.::: :. :::..: : .. ::.. : ::. ::: ::.:::::::::::::::::
NP_001 IGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 PRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKGR
:::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.::
NP_001 PRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRGR
430 440 450 460 470 480
460 470 480 490
pF1KB3 TFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
::..:. .: .: : .:.. ..
NP_001 TFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
>>XP_016874334 (OMIM: 611039) PREDICTED: solute carrier (521 aa)
initn: 2016 init1: 2016 opt: 2055 Z-score: 2464.0 bits: 465.5 E(85289): 1.6e-130
Smith-Waterman score: 2055; 64.2% identity (86.3% similar) in 475 aa overlap (7-481:30-503)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQ
:.: :..:. :..::.::::::::::::.
XP_016 MDNRQNGGSFLCTSEDDRQENKVENNKEVKVTPALIFAITVATIGSFQFGYNTGVINAPE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 KVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::
XP_016 TIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALG
..:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.:
XP_016 IVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 TLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLIN
::.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: :::::::::::
XP_016 TLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLIN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 RNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVV
:..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..:
XP_016 RKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLH
::::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::
XP_016 LQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLH
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQ
.:::.::: :. :::..: : .. ::.. : ::. ::: ::.::::::::::::::::
XP_016 MIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 GPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKG
::::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.:
XP_016 GPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRG
430 440 450 460 470 480
460 470 480 490
pF1KB3 RTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
:::..:. .: .: : .:.. ..
XP_016 RTFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
>>XP_016874332 (OMIM: 611039) PREDICTED: solute carrier (521 aa)
initn: 2016 init1: 2016 opt: 2055 Z-score: 2464.0 bits: 465.5 E(85289): 1.6e-130
Smith-Waterman score: 2055; 64.2% identity (86.3% similar) in 475 aa overlap (7-481:30-503)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQ
:.: :..:. :..::.::::::::::::.
XP_016 MDNRQNGGSFLCTSEDDRQENKVENNKEVKVTPALIFAITVATIGSFQFGYNTGVINAPE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 KVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::
XP_016 TIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALG
..:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.:
XP_016 IVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 TLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLIN
::.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: :::::::::::
XP_016 TLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLIN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 RNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVV
:..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..:
XP_016 RKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLH
::::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::
XP_016 LQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLH
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQ
.:::.::: :. :::..: : .. ::.. : ::. ::: ::.::::::::::::::::
XP_016 MIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 GPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKG
::::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.:
XP_016 GPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRG
430 440 450 460 470 480
460 470 480 490
pF1KB3 RTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
:::..:. .: .: : .:.. ..
XP_016 RTFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
>>XP_016874331 (OMIM: 611039) PREDICTED: solute carrier (521 aa)
initn: 2016 init1: 2016 opt: 2055 Z-score: 2464.0 bits: 465.5 E(85289): 1.6e-130
Smith-Waterman score: 2055; 64.2% identity (86.3% similar) in 475 aa overlap (7-481:30-503)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQ
:.: :..:. :..::.::::::::::::.
XP_016 MDNRQNGGSFLCTSEDDRQENKVENNKEVKVTPALIFAITVATIGSFQFGYNTGVINAPE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 KVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::
XP_016 TIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALG
..:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.:
XP_016 IVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 TLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLIN
::.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: :::::::::::
XP_016 TLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLIN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 RNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVV
:..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..:
XP_016 RKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLH
::::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::
XP_016 LQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLH
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQ
.:::.::: :. :::..: : .. ::.. : ::. ::: ::.::::::::::::::::
XP_016 MIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 GPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKG
::::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.:
XP_016 GPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRG
430 440 450 460 470 480
460 470 480 490
pF1KB3 RTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
:::..:. .: .: : .:.. ..
XP_016 RTFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
>>XP_016874330 (OMIM: 611039) PREDICTED: solute carrier (521 aa)
initn: 2016 init1: 2016 opt: 2055 Z-score: 2464.0 bits: 465.5 E(85289): 1.6e-130
Smith-Waterman score: 2055; 64.2% identity (86.3% similar) in 475 aa overlap (7-481:30-503)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQ
:.: :..:. :..::.::::::::::::.
XP_016 MDNRQNGGSFLCTSEDDRQENKVENNKEVKVTPALIFAITVATIGSFQFGYNTGVINAPE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 KVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::
XP_016 TIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALG
..:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.:
XP_016 IVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 TLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLIN
::.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: :::::::::::
XP_016 TLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLIN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 RNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVV
:..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..:
XP_016 RKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLH
::::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::
XP_016 LQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLH
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQ
.:::.::: :. :::..: : .. ::.. : ::. ::: ::.::::::::::::::::
XP_016 MIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 GPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKG
::::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.:
XP_016 GPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRG
430 440 450 460 470 480
460 470 480 490
pF1KB3 RTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
:::..:. .: .: : .:.. ..
XP_016 RTFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
>>XP_016874333 (OMIM: 611039) PREDICTED: solute carrier (521 aa)
initn: 2016 init1: 2016 opt: 2055 Z-score: 2464.0 bits: 465.5 E(85289): 1.6e-130
Smith-Waterman score: 2055; 64.2% identity (86.3% similar) in 475 aa overlap (7-481:30-503)
10 20 30
pF1KB3 MEPSSKKLTGRLMLAVGGAVLGSLQFGYNTGVINAPQ
:.: :..:. :..::.::::::::::::.
XP_016 MDNRQNGGSFLCTSEDDRQENKVENNKEVKVTPALIFAITVATIGSFQFGYNTGVINAPE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB3 KVIEEFYNQTWVHRYGESILPTTLTTLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
.:.:: :.: . . . . ::.::::::::::::::::::::::::::::::::::
XP_016 TIIKEFINKTLTDKANAPPSEVLLTNLWSLSVAIFSVGGMIGSFSVGLFVNRFGRRNSML
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB3 MMNLLAFVSAVLMGFSKLGKSFEMLILGRFIIGVYCGLTTGFVPMYVGEVSPTALRGALG
..:::: ... :::. :...: :::::::..::..::: :::::::.::.::::::::.:
XP_016 IVNLLAATGGCLMGLCKIAESVEMLILGRLVIGLFCGLCTGFVPMYIGEISPTALRGAFG
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB3 TLHQLGIVVGILIAQVFGLDSIMGNKDLWPLLLSIIFIPALLQCIVLPFCPESPRFLLIN
::.:::::.:::.::.:::. :.:...:::.::.. ..::.:: .:: :::::::::::
XP_016 TLNQLGIVIGILVAQIFGLELILGSEELWPVLLGFTILPAILQSAALPCCPESPRFLLIN
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB3 RNEENRAKSVLKKLRGTADVTHDLQEMKEESRQMMREKKVTILELFRSPAYRQPILIAVV
:..:. : .:..: :: ::..:.::::.:: .: .::.::.::::: .:::::.:..:
XP_016 RKKEENATRILQRLWGTQDVSQDIQEMKDESARMSQEKQVTVLELFRVSSYRQPIIISIV
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB3 LQLSQQLSGINAVFYYSTSIFEKAGVQQPVYATIGSGIVNTAFTVVSLFVVERAGRRTLH
::::::::::::::::::.::. ::::::.::::..:.::: ::..:::.::::::::::
XP_016 LQLSQQLSGINAVFYYSTGIFKDAGVQQPIYATISAGVVNTIFTLLSLFLVERAGRRTLH
310 320 330 340 350 360
340 350 360 370 380 390
pF1KB3 LIGLAGMAGCAILMTIALALLEQLPWMSYLSIVAIFGFVAFFEVGPGPIPWFIVAELFSQ
.:::.::: :. :::..: : .. ::.. : ::. ::: ::.::::::::::::::::
XP_016 MIGLGGMAFCSTLMTVSLLLKNHYNGMSFVCIGAILVFVACFEIGPGPIPWFIVAELFSQ
370 380 390 400 410 420
400 410 420 430 440 450
pF1KB3 GPRPAAIAVAGFSNWTSNFIVGMCFQYVEQLCGPYVFIIFTVLLVLFFIFTYFKVPETKG
::::::.:::: :::::::.::. : . : ::::::: .:. :. ::.::::::.:
XP_016 GPRPAAMAVAGCSNWTSNFLVGLLFPSAAYYLGAYVFIIFTGFLITFLAFTFFKVPETRG
430 440 450 460 470 480
460 470 480 490
pF1KB3 RTFDEIASGFRQGGASQSDKTPEELFHPLGADSQV
:::..:. .: .: : .:.. ..
XP_016 RTFEDITRAF-EGQAHGADRSGKDGVMGMNSIEPAKETTTNV
490 500 510 520
492 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 13:22:47 2016 done: Thu Nov 3 13:22:48 2016
Total Scan time: 7.250 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]