Result of FASTA (omim) for
pFN21AB3107
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB3107, 165 aa
1>>>pF1KB3107 165 - 165 aa - 165 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2872+/-0.00028; mu= 13.5763+/- 0.018
mean_var=101.9788+/-21.673, 0's: 0 Z-trim(121.7): 341 B-trim: 2036 in 1/51
Lambda= 0.127005
statistics sampled from 38150 (38576) to 38150 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.798), E-opt: 0.2 (0.452), width: 16
Scan time: 5.240
The best scores are: opt bits E(85289)
XP_005271348 (OMIM: 603129) PREDICTED: LIM domain ( 165) 1202 229.5 1.9e-60
NP_006760 (OMIM: 603129) LIM domain transcription ( 165) 1202 229.5 1.9e-60
XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 554 110.7 9.5e-25
XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 ( 145) 554 110.7 9.5e-25
NP_001257357 (OMIM: 186921) rhombotin-1 isoform b ( 155) 554 110.8 1e-24
NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Ho ( 156) 554 110.8 1e-24
XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 ( 193) 554 110.9 1.2e-24
NP_001230538 (OMIM: 180386) LIM domain only protei ( 145) 539 108.0 6.4e-24
XP_006719173 (OMIM: 180386) PREDICTED: LIM domain ( 145) 539 108.0 6.4e-24
XP_011519065 (OMIM: 180386) PREDICTED: LIM domain ( 145) 539 108.0 6.4e-24
NP_001001395 (OMIM: 180386) LIM domain only protei ( 145) 539 108.0 6.4e-24
XP_011519064 (OMIM: 180386) PREDICTED: LIM domain ( 145) 539 108.0 6.4e-24
XP_006719174 (OMIM: 180386) PREDICTED: LIM domain ( 145) 539 108.0 6.4e-24
NP_061110 (OMIM: 180386) LIM domain only protein 3 ( 145) 539 108.0 6.4e-24
NP_001230539 (OMIM: 180386) LIM domain only protei ( 145) 539 108.0 6.4e-24
NP_001230540 (OMIM: 180386) LIM domain only protei ( 156) 539 108.0 6.7e-24
NP_001230541 (OMIM: 180386) LIM domain only protei ( 163) 539 108.0 6.9e-24
NP_001135787 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 451 91.9 4.8e-19
XP_016873222 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
NP_001135788 (OMIM: 180385) rhombotin-2 isoform 2 ( 158) 451 91.9 4.8e-19
XP_016873219 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
XP_016873220 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
XP_016873218 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
XP_016873216 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
XP_005252978 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
XP_016873217 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
XP_016873221 (OMIM: 180385) PREDICTED: rhombotin-2 ( 158) 451 91.9 4.8e-19
NP_005565 (OMIM: 180385) rhombotin-2 isoform 1 [Ho ( 227) 451 92.1 6.2e-19
NP_203129 (OMIM: 262700,602146) LIM/homeobox prote ( 390) 427 87.9 1.9e-17
XP_005245407 (OMIM: 606066) PREDICTED: LIM/homeobo ( 336) 426 87.7 1.9e-17
XP_016857338 (OMIM: 606066) PREDICTED: LIM/homeobo ( 378) 426 87.7 2.1e-17
NP_001014434 (OMIM: 606066) LIM/homeobox protein L ( 388) 426 87.7 2.1e-17
NP_064589 (OMIM: 606066) LIM/homeobox protein Lhx9 ( 397) 426 87.7 2.2e-17
XP_011508083 (OMIM: 606066) PREDICTED: LIM/homeobo ( 403) 426 87.8 2.2e-17
XP_006717386 (OMIM: 603759) PREDICTED: LIM/homeobo ( 314) 417 86.0 5.8e-17
NP_004780 (OMIM: 603759) LIM/homeobox protein Lhx2 ( 406) 417 86.1 6.8e-17
XP_016870657 (OMIM: 221750,600577) PREDICTED: LIM/ ( 373) 405 83.9 3e-16
XP_005263467 (OMIM: 221750,600577) PREDICTED: LIM/ ( 386) 405 83.9 3e-16
NP_835258 (OMIM: 221750,600577) LIM/homeobox prote ( 397) 405 83.9 3.1e-16
NP_055379 (OMIM: 221750,600577) LIM/homeobox prote ( 402) 405 83.9 3.1e-16
NP_665804 (OMIM: 609481) insulin gene enhancer pro ( 359) 395 82.0 1e-15
XP_016877994 (OMIM: 609481) PREDICTED: insulin gen ( 534) 395 82.2 1.3e-15
NP_071758 (OMIM: 605992) LIM/homeobox protein Lhx5 ( 402) 388 80.8 2.7e-15
NP_001243043 (OMIM: 604425) LIM/homeobox protein L ( 346) 387 80.5 2.8e-15
NP_001001933 (OMIM: 604425) LIM/homeobox protein L ( 356) 387 80.5 2.8e-15
XP_016856806 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 387 80.6 2.9e-15
XP_016856805 (OMIM: 604425) PREDICTED: LIM/homeobo ( 363) 387 80.6 2.9e-15
XP_005251973 (OMIM: 608215) PREDICTED: LIM/homeobo ( 230) 382 79.4 4e-15
NP_001229263 (OMIM: 608215) LIM/homeobox protein L ( 363) 382 79.6 5.4e-15
NP_001229262 (OMIM: 608215) LIM/homeobox protein L ( 366) 382 79.6 5.4e-15
>>XP_005271348 (OMIM: 603129) PREDICTED: LIM domain tran (165 aa)
initn: 1202 init1: 1202 opt: 1202 Z-score: 1206.3 bits: 229.5 E(85289): 1.9e-60
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
70 80 90 100 110 120
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:::::::::::::::::::::::::::::::::::::::::::::
XP_005 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
130 140 150 160
>>NP_006760 (OMIM: 603129) LIM domain transcription fact (165 aa)
initn: 1202 init1: 1202 opt: 1202 Z-score: 1206.3 bits: 229.5 E(85289): 1.9e-60
Smith-Waterman score: 1202; 100.0% identity (100.0% similar) in 165 aa overlap (1-165:1-165)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
70 80 90 100 110 120
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:::::::::::::::::::::::::::::::::::::::::::::
NP_006 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
130 140 150 160
>>XP_011518401 (OMIM: 186921) PREDICTED: rhombotin-1 iso (145 aa)
initn: 635 init1: 551 opt: 554 Z-score: 565.3 bits: 110.7 E(85289): 9.5e-25
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:11-142)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
: ::::. :: ::.:: :.:.::: ::::.::. .::..
XP_011 MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
:.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : .
XP_011 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ
60 70 80 90 100 110
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:. ::.: :. ..:. : . .:: ..:
XP_011 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
120 130 140
>>XP_011518400 (OMIM: 186921) PREDICTED: rhombotin-1 iso (145 aa)
initn: 635 init1: 551 opt: 554 Z-score: 565.3 bits: 110.7 E(85289): 9.5e-25
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:11-142)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
: ::::. :: ::.:: :.:.::: ::::.::. .::..
XP_011 MLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
:.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : .
XP_011 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ
60 70 80 90 100 110
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:. ::.: :. ..:. : . .:: ..:
XP_011 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
120 130 140
>>NP_001257357 (OMIM: 186921) rhombotin-1 isoform b [Hom (155 aa)
initn: 638 init1: 554 opt: 554 Z-score: 564.9 bits: 110.8 E(85289): 1e-24
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:21-152)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
: ::::. :: ::.:: :.:.::: ::::.::. .::..
NP_001 MVLDQEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
:.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. : .
NP_001 GSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCNQ
70 80 90 100 110 120
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:. ::.: :. ..:. : . .:: ..:
NP_001 RFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
130 140 150
>>NP_002306 (OMIM: 186921) rhombotin-1 isoform a [Homo s (156 aa)
initn: 638 init1: 554 opt: 554 Z-score: 564.9 bits: 110.8 E(85289): 1e-24
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:22-153)
10 20 30 40 50
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGD
: ::::. :: ::.:: :.:.::: ::::.::. .::.
NP_002 MMVLDKEDGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGE
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB3 IGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCR
.:.. :::...:::: ::.::::..: :.::.. ::: :.::::. ::::: ::.:. :
NP_002 VGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHLDCFACQLCN
70 80 90 100 110 120
120 130 140 150 160
pF1KB3 NRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
.:. ::.: :. ..:. : . .:: ..:
NP_002 QRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
130 140 150
>>XP_006718291 (OMIM: 186921) PREDICTED: rhombotin-1 iso (193 aa)
initn: 601 init1: 551 opt: 554 Z-score: 563.8 bits: 110.9 E(85289): 1.2e-24
Smith-Waterman score: 554; 52.3% identity (78.8% similar) in 132 aa overlap (21-152:59-190)
10 20 30 40 50
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKC
: ::::. :: ::.:: :.:.::: ::::
XP_006 GEVDVLGWKSGLGGAHWGVPMLSVQPKGKQKGCAGCNRKIKDRYLLKALDKYWHEDCLKC
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB3 SCCQAQLGDIGTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHL
.::. .::..:.. :::...:::: ::.::::..: :.::.. ::: :.::::. :::::
XP_006 ACCDCRLGEVGSTLYTKANLILCRRDYLRLFGTTGNCAACSKLIPAFEMVMRARDNVYHL
90 100 110 120 130 140
120 130 140 150 160
pF1KB3 KCFTCSTCRNRLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
::.:. : .:. ::.: :. ..:. : . .:: ..:
XP_006 DCFACQLCNQRFCVGDKFFLKNNMILCQMDYEEGQLNGTFESQVQ
150 160 170 180 190
>>NP_001230538 (OMIM: 180386) LIM domain only protein 3 (145 aa)
initn: 546 init1: 508 opt: 539 Z-score: 550.4 bits: 108.0 E(85289): 6.4e-24
Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
: ::::. :: ::.:: :.:.::: ::::.::. .::..
NP_001 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
:.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : .
NP_001 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ
60 70 80 90 100 110
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:. ::.: :. ..:. : .:.
NP_001 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
120 130 140
>>XP_006719173 (OMIM: 180386) PREDICTED: LIM domain only (145 aa)
initn: 546 init1: 508 opt: 539 Z-score: 550.4 bits: 108.0 E(85289): 6.4e-24
Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
: ::::. :: ::.:: :.:.::: ::::.::. .::..
XP_006 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
:.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : .
XP_006 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ
60 70 80 90 100 110
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:. ::.: :. ..:. : .:.
XP_006 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
120 130 140
>>XP_011519065 (OMIM: 180386) PREDICTED: LIM domain only (145 aa)
initn: 546 init1: 508 opt: 539 Z-score: 550.4 bits: 108.0 E(85289): 6.4e-24
Smith-Waterman score: 539; 53.2% identity (78.6% similar) in 126 aa overlap (21-146:11-136)
10 20 30 40 50 60
pF1KB3 MVNPGSSSQPPPVTAGSLSWKRCAGCGGKIADRFLLYAMDSYWHSRCLKCSCCQAQLGDI
: ::::. :: ::.:: :.:.::: ::::.::. .::..
XP_011 MLSVQPDTKPKGCAGCNRKIKDRYLLKALDKYWHEDCLKCACCDCRLGEV
10 20 30 40 50
70 80 90 100 110 120
pF1KB3 GTSCYTKSGMILCRNDYIRLFGNSGACSACGQSIPASELVMRAQGNVYHLKCFTCSTCRN
:.. :::...:::: ::.:::: .: :.::.. ::: :.::::. ::::: ::.:. : .
XP_011 GSTLYTKANLILCRRDYLRLFGVTGNCAACSKLIPAFEMVMRAKDNVYHLDCFACQLCNQ
60 70 80 90 100 110
130 140 150 160
pF1KB3 RLVPGDRFHYINGSLFCEHDRPTALINGHLNSLQSNPLLPDQKVC
:. ::.: :. ..:. : .:.
XP_011 RFCVGDKFFLKNNMILCQTDYEEGLMKEGYAPQVR
120 130 140
165 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Thu Nov 3 12:27:23 2016 done: Thu Nov 3 12:27:24 2016
Total Scan time: 5.240 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]